메뉴 건너뛰기




Volumn 88, Issue 4, 1996, Pages 569-576

Treatment of established adjuvant arthritis in rats with monoclonal antibody to CD18 and very late activation antigen-4 integrins suppresses neutrophil and T-lymphocyte migration to the joints and improves clinical disease

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CD18 ANTIGEN; INTEGRIN; MONOCLONAL ANTIBODY;

EID: 0030035865     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.d01-695.x     Document Type: Article
Times cited : (59)

References (51)
  • 1
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • SPRINGER T.A. (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76, 301.
    • (1994) Cell , vol.76 , pp. 301
    • Springer, T.A.1
  • 2
    • 0027935309 scopus 로고
    • Leukocyte-endothelial adhesion molecules
    • CARLOS T.M. & HARLAN J.M. (1994) Leukocyte-endothelial adhesion molecules. Blood 84, 2068.
    • (1994) Blood , vol.84 , pp. 2068
    • Carlos, T.M.1    Harlan, J.M.2
  • 3
    • 0027407109 scopus 로고
    • Endothelial-leukocyte adhesion molecules
    • BEVILACQUA M.P. (1993) Endothelial-leukocyte adhesion molecules. Annu Rev Immunol 11, 767.
    • (1993) Annu Rev Immunol , vol.11 , pp. 767
    • Bevilacqua, M.P.1
  • 4
    • 0027285631 scopus 로고
    • Adhesion molecules in cell interactions
    • HOGG N. & LANDIS R.C. (1993) Adhesion molecules in cell interactions. Curr Opin Immunol 5, 383.
    • (1993) Curr Opin Immunol , vol.5 , pp. 383
    • Hogg, N.1    Landis, R.C.2
  • 6
    • 0027248750 scopus 로고
    • PECAM-1 is required for transendothelial migration of leukocytes
    • MULLER W.A., WEIGL S.A., DENG X. & PHILLIPS D.M. (1993) PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 178, 449.
    • (1993) J Exp Med , vol.178 , pp. 449
    • Muller, W.A.1    Weigl, S.A.2    Deng, X.3    Phillips, D.M.4
  • 8
    • 0026520089 scopus 로고
    • Leukocyte adhesion deficiency: Clinical and postmortem observations
    • HAWKINS H.K., MAFFELFINGER S.C. & ANDERSON D.C. (1992) Leukocyte adhesion deficiency: clinical and postmortem observations. Pediatr Pathol 12, 119.
    • (1992) Pediatr Pathol , vol.12 , pp. 119
    • Hawkins, H.K.1    Maffelfinger, S.C.2    Anderson, D.C.3
  • 9
    • 0028208244 scopus 로고
    • Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4
    • VONDERHEIDE R.H., TEDDER T.F., SPRINGER T.A. & STAUNTON D.E. (1994) Residues within a conserved amino acid motif of domains 1 and 4 of VCAM-1 are required for binding to VLA-4. J Cell Biol 125, 215.
    • (1994) J Cell Biol , vol.125 , pp. 215
    • Vonderheide, R.H.1    Tedder, T.F.2    Springer, T.A.3    Staunton, D.E.4
  • 11
    • 0028294140 scopus 로고
    • Monocytes use either CD11 CD18 or VLA-4 to migrate across human endothelium in vitro
    • MEERSCHAERT J. & FURIE M.B. (1994) Monocytes use either CD11 CD18 or VLA-4 to migrate across human endothelium in vitro. J Immunol 152, 1915.
    • (1994) J Immunol , vol.152 , pp. 1915
    • Meerschaert, J.1    Furie, M.B.2
  • 12
    • 0029061303 scopus 로고
    • In vivo blood monocyte migration to acute inflammatory reactions, IL-1α, TNF-α, IFM-gamma, and C5a utilizes LFA-1, Mac-1, and VLA-4: The relative importance of each integrin
    • ISSEKUTZ T.B. (1995) In vivo blood monocyte migration to acute inflammatory reactions, IL-1α, TNF-α, IFM-gamma, and C5a utilizes LFA-1, Mac-1, and VLA-4: the relative importance of each integrin. J Immunol 154, 6533.
    • (1995) J Immunol , vol.154 , pp. 6533
    • Issekutz, T.B.1
  • 13
    • 0027217903 scopus 로고
    • CD18-independent neutrophil and mononuclear leukocyte emigration into the peritoneum of rabbits
    • WINN R.K. & HARLAN J.M. (1993) CD18-independent neutrophil and mononuclear leukocyte emigration into the peritoneum of rabbits. J Clin Invest 92, 1168.
    • (1993) J Clin Invest , vol.92 , pp. 1168
    • Winn, R.K.1    Harlan, J.M.2
  • 14
    • 0027145638 scopus 로고
    • The VLA-4 integrin can mediate CD11/CD18 independent transendothelial migration of human monocytes
    • CHULUYAN H.E. & ISSEKUTZ A.C. (1993) The VLA-4 integrin can mediate CD11/CD18 independent transendothelial migration of human monocytes. J Clin Invest 92, 2768.
    • (1993) J Clin Invest , vol.92 , pp. 2768
    • Chuluyan, H.E.1    Issekutz, A.C.2
  • 15
    • 0028963907 scopus 로고
    • Monocyte migration to arthritis in the rat utilizes both CD11/CD18 and very late activation antigen 4 integrin mechanisms
    • ISSEKUTZ A.C. & ISSEKUTZ T.B. (1995) Monocyte migration to arthritis in the rat utilizes both CD11/CD18 and very late activation antigen 4 integrin mechanisms. J Exp Med 181, 1197.
    • (1995) J Exp Med , vol.181 , pp. 1197
    • Issekutz, A.C.1    Issekutz, T.B.2
  • 16
    • 0025304539 scopus 로고
    • Rheumatoid arthritis : Pathophysiology and implication for therapy
    • HARRIS E.D. (1990) Rheumatoid arthritis : pathophysiology and implication for therapy. N Engl J Med 322, 1277.
    • (1990) N Engl J Med , vol.322 , pp. 1277
    • Harris, E.D.1
  • 17
    • 0023832901 scopus 로고
    • Polymorphonuclear leukocytes induce damage to the articular cartilage in acute immunologic arthritis in rabbits
    • FOSTER S.J., CUNLIFFE D.J. & MCCORMICK M.E. (1988) Polymorphonuclear leukocytes induce damage to the articular cartilage in acute immunologic arthritis in rabbits. Biochem Phurmacol 37, 1181.
    • (1988) Biochem Phurmacol , vol.37 , pp. 1181
    • Foster, S.J.1    Cunliffe, D.J.2    Mccormick, M.E.3
  • 18
    • 0026461963 scopus 로고
    • Mechanisms of host tissue damage by cytokine-activated neutrophils
    • FERRANTE A., KOWANKO I.C. & BATES E.J. (1992) Mechanisms of host tissue damage by cytokine-activated neutrophils. Immunol Ser 57, 499.
    • (1992) Immunol Ser , vol.57 , pp. 499
    • Ferrante, A.1    Kowanko, I.C.2    Bates, E.J.3
  • 19
    • 0028903607 scopus 로고
    • The role of adhesion molecules in the development of autoimmune arthritis
    • MIKECZ K., BRENNAN F.R., KIMM J.H. & GLANT T.T. (1995) The role of adhesion molecules in the development of autoimmune arthritis. Scand J Rheumatol 24, 99.
    • (1995) Scand J Rheumatol , vol.24 , pp. 99
    • Mikecz, K.1    Brennan, F.R.2    Kimm, J.H.3    Glant, T.T.4
  • 20
    • 0026348189 scopus 로고
    • ICAM-1-dependent pathway is critically involved in the pathogenesis of adjuvant arthritis in rats
    • IIGO Y., TAKASHI T., TAMATANI T. et al. (1991) ICAM-1-dependent pathway is critically involved in the pathogenesis of adjuvant arthritis in rats. J Immunol 147, 4167.
    • (1991) J Immunol , vol.147 , pp. 4167
    • Iigo, Y.1    Takashi, T.2    Tamatani, T.3
  • 21
    • 0028083224 scopus 로고
    • Synthetic fibronectin peptides suppress arthritis in rats by interrupting leukocyte adhesion and recruitment
    • WAHL S.M., ALLEN J.B., HINES K.L. et al. (1994) Synthetic fibronectin peptides suppress arthritis in rats by interrupting leukocyte adhesion and recruitment. J Clin Invest 94, 655.
    • (1994) J Clin Invest , vol.94 , pp. 655
    • Wahl, S.M.1    Allen, J.B.2    Hines, K.L.3
  • 22
    • 0026725640 scopus 로고
    • Amelioration of antigen-induced arthritis in rabbits treated with monoclonal antibodies to leukocyte adhesion molecules
    • JASIN H.E., LIGHTFOOT E., DAVIS L.S., ROTHLEIN R., FAANES R.B. & LIPSKY P.E. (1992) Amelioration of antigen-induced arthritis in rabbits treated with monoclonal antibodies to leukocyte adhesion molecules. Arthritis Rheum 35, 541.
    • (1992) Arthritis Rheum , vol.35 , pp. 541
    • Jasin, H.E.1    Lightfoot, E.2    Davis, L.S.3    Rothlein, R.4    Faanes, R.B.5    Lipsky, P.E.6
  • 23
    • 0026647093 scopus 로고
    • Increased binding of synovial T lymphocytes from rheumatoid arthritis to endothelial-leukocyte adhesion molecule-1 (ELAM-I) and vascular cell adhesion molecule-1 (VCAM-1)
    • POSTIGO A.A., GARCIA-VICUÑA R., DIAZ-GONZALEZ F. et al. (1992) Increased binding of synovial T lymphocytes from rheumatoid arthritis to endothelial-leukocyte adhesion molecule-1 (ELAM-I) and vascular cell adhesion molecule-1 (VCAM-1). J Clin Invest 89, 1445.
    • (1992) J Clin Invest , vol.89 , pp. 1445
    • Postigo, A.A.1    Garcia-Vicuña, R.2    Diaz-Gonzalez, F.3
  • 25
    • 0028125641 scopus 로고
    • Differential distribution of intercellular adhesion molecules (ICAM-1, ICAM-2, and ICAM-3) and the MS-1 antigen in normal and diseased human synovia: Their possible pathogenetic and clinical significance in rheumatoid arthritis
    • SZEKANECZ Z., HAINES G.K., LIN T.R. et al. (1994) Differential distribution of intercellular adhesion molecules (ICAM-1, ICAM-2, and ICAM-3) and the MS-1 antigen in normal and diseased human synovia: their possible pathogenetic and clinical significance in rheumatoid arthritis. Arthritis Rheum 37, 221.
    • (1994) Arthritis Rheum , vol.37 , pp. 221
    • Szekanecz, Z.1    Haines, G.K.2    Lin, T.R.3
  • 26
    • 0027536187 scopus 로고
    • Detection of increased levels of circulating intercellular adhesion molecule 1 in some patients with rheumatoid arthritis but not in patients with systemic lupus erythematosus: Lack of correlation with levels of circulating vascular cell adhesion molecule 1
    • MASON J.C., KAPAHI P. & HASKARD D.O. (1993) Detection of increased levels of circulating intercellular adhesion molecule 1 in some patients with rheumatoid arthritis but not in patients with systemic lupus erythematosus: lack of correlation with levels of circulating vascular cell adhesion molecule 1. Arthritis Rheum 36, 519.
    • (1993) Arthritis Rheum , vol.36 , pp. 519
    • Mason, J.C.1    Kapahi, P.2    Haskard, D.O.3
  • 27
    • 0027220527 scopus 로고
    • Increased levels of circulating intercellular adhesion molecule 1 in the sera of patients with rheumatoid arthritis
    • CUSH J.J., ROTHLEIN R., LINDSLEY H.B., MAINOLFI E.A. & LISPKY P.E. (1993) Increased levels of circulating intercellular adhesion molecule 1 in the sera of patients with rheumatoid arthritis. Arthritis Rheum 36, 1098.
    • (1993) Arthritis Rheum , vol.36 , pp. 1098
    • Cush, J.J.1    Rothlein, R.2    Lindsley, H.B.3    Mainolfi, E.A.4    Lispky, P.E.5
  • 28
    • 0027241419 scopus 로고
    • Soluble intercellular adhesion molecule-1 (sICAM-1) in patients with rheumatoid arthritis and systemic lupus erythema-tosus
    • MACHOLD K.P., KIENER H.P., GRANINGER W. & GRANINGER W.B. (1993) Soluble intercellular adhesion molecule-1 (sICAM-1) in patients with rheumatoid arthritis and systemic lupus erythema-tosus. Clin Immunol Immunopathol 68, 74.
    • (1993) Clin Immunol Immunopathol , vol.68 , pp. 74
    • Machold, K.P.1    Kiener, H.P.2    Graninger, W.3    Graninger, W.B.4
  • 29
    • 0028355977 scopus 로고
    • Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule 1
    • KAVANAUGH A.F., DAVIS L.S., NICHOLS L.A. et al. (1994) Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule 1. Arthritis Rheum 37, 992.
    • (1994) Arthritis Rheum , vol.37 , pp. 992
    • Kavanaugh, A.F.1    Davis, L.S.2    Nichols, L.A.3
  • 30
    • 0027255804 scopus 로고
    • A major portion of polymorphonuclear leukocyte and T lymphocyte migration to arthritic joints in the rat is via LFA-1/MAC-1-independent mechanisms
    • ISSEKUTZ A.C. & ISSEKUTZ T.B. (1993) A major portion of polymorphonuclear leukocyte and T lymphocyte migration to arthritic joints in the rat is via LFA-1/MAC-1-independent mechanisms. Clin Immunol Immunopathol 67, 257.
    • (1993) Clin Immunol Immunopathol , vol.67 , pp. 257
    • Issekutz, A.C.1    Issekutz, T.B.2
  • 31
    • 0026326328 scopus 로고
    • T lymphocyte migration to arthritic joints and dermal inflammation in the rat: Differing migration patterns and the involvement of VLA-4
    • ISSEKUTZ T.B. & ISSEKUTZ A.C. (1991) T lymphocyte migration to arthritic joints and dermal inflammation in the rat: differing migration patterns and the involvement of VLA-4. Clin Immunol Immunopathol 61, 436.
    • (1991) Clin Immunol Immunopathol , vol.61 , pp. 436
    • Issekutz, T.B.1    Issekutz, A.C.2
  • 33
    • 0025942325 scopus 로고
    • Effect of a new monoclonal antibody, TA-2, that inhibits lymphocyte adherence to cytokine stimulated endothelium in the rat
    • ISSEKUTZ T.B. & WYKRETOWICZ A. (1991) Effect of a new monoclonal antibody, TA-2, that inhibits lymphocyte adherence to cytokine stimulated endothelium in the rat. J Immunol 147, 109.
    • (1991) J Immunol , vol.147 , pp. 109
    • Issekutz, T.B.1    Wykretowicz, A.2
  • 34
    • 0026343689 scopus 로고
    • Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody: A likely role for VLA-4 in vivo
    • ISSEKUTZ T.B. (1991) Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody: a likely role for VLA-4 in vivo. J Immunol 147, 4178.
    • (1991) J Immunol , vol.147 , pp. 4178
    • Issekutz, T.B.1
  • 35
    • 0025974691 scopus 로고
    • Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies
    • TAMATANI T., KOTANI M. & MIYASAKA M. (1991) Characterization of the rat leukocyte integrin, CD11/CD18, by the use of LFA-1 subunit-specific monoclonal antibodies. Eur J Immunol 21, 627.
    • (1991) Eur J Immunol , vol.21 , pp. 627
    • Tamatani, T.1    Kotani, M.2    Miyasaka, M.3
  • 36
    • 0026774801 scopus 로고
    • The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of polymorphonuclear leucocytes to inflammatory reactions in the rat
    • ISSEKUTZ A.C. & ISSEKUTZ T.B. (1992) The contribution of LFA-1 (CD11a/CD18) and MAC-1 (CD11b/CD18) to the in vivo migration of polymorphonuclear leucocytes to inflammatory reactions in the rat. Immunology 76, 655.
    • (1992) Immunology , vol.76 , pp. 655
    • Issekutz, A.C.1    Issekutz, T.B.2
  • 37
    • 0025823186 scopus 로고
    • Quantitation and kinetics of polymorphonuclear leukocyte and lymphocyte accumulation in joints during adjuvant arthritis in the rat
    • ISSEKUTZ A.C. & ISSEKUTZ T.B. (1991) Quantitation and kinetics of polymorphonuclear leukocyte and lymphocyte accumulation in joints during adjuvant arthritis in the rat. Lab Invest 64, 656.
    • (1991) Lab Invest , vol.64 , pp. 656
    • Issekutz, A.C.1    Issekutz, T.B.2
  • 39
    • 0023614493 scopus 로고
    • Harvesting the noncirculating pool of polymorphonuclear leukocytes in rats by hetastarch exchange transfusion (HET): Yield and functional assessment
    • WILLIAMS W.H. Jr., MOSER K.M., ULICH T. & CAIRO M.S. (1987) Harvesting the noncirculating pool of polymorphonuclear leukocytes in rats by hetastarch exchange transfusion (HET): yield and functional assessment. J Leukocyte Biol 42, 455.
    • (1987) J Leukocyte Biol , vol.42 , pp. 455
    • Williams Jr., W.H.1    Moser, K.M.2    Ulich, T.3    Cairo, M.S.4
  • 41
    • 0025856309 scopus 로고
    • Role of lymphocyte adhesion receptors in transient interactions and cell locomotion
    • DUSTIN M. L. & SPRINGER T. A. (1991) Role of lymphocyte adhesion receptors in transient interactions and cell locomotion. Annu Rev Immunol 9, 27.
    • (1991) Annu Rev Immunol , vol.9 , pp. 27
    • Dustin, M.L.1    Springer, T.A.2
  • 42
    • 0028116223 scopus 로고
    • Neutrophils migrate to delayed-type hypersensitivity reactions in joints, but not in skin: The mechanism is LFA-1/Mac-1 independent
    • GAO J.X., ISSEKUTZ A.C. & ISSEKUTZ T.B. (1994) Neutrophils migrate to delayed-type hypersensitivity reactions in joints, but not in skin: the mechanism is LFA-1/Mac-1 independent. J Immunol 153, 5689.
    • (1994) J Immunol , vol.153 , pp. 5689
    • Gao, J.X.1    Issekutz, A.C.2    Issekutz, T.B.3
  • 43
    • 0025230704 scopus 로고
    • Cd18-dependent and -independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits
    • DOERSCHUK C.M., WINN R.K., COXSON H.O. & HARLAN J.M. (1990) Cd18-dependent and -independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits. J Immunol 144, 2327.
    • (1990) J Immunol , vol.144 , pp. 2327
    • Doerschuk, C.M.1    Winn, R.K.2    Coxson, H.O.3    Harlan, J.M.4
  • 44
    • 0028966515 scopus 로고
    • CD11/CD18 independent transendothelial migration of human polymorphonuclear leukocytes (PMNL) and monocytes: Involvement of distinct and unique mechanisms
    • ISSEKUTZ A.C., CHULUYAN H.E. & LOPES N. (1995) CD11/CD18 independent transendothelial migration of human polymorphonuclear leukocytes (PMNL) and monocytes: involvement of distinct and unique mechanisms. J Leukocyte Biol 57, 553.
    • (1995) J Leukocyte Biol , vol.57 , pp. 553
    • Issekutz, A.C.1    Chuluyan, H.E.2    Lopes, N.3
  • 45
    • 0027377497 scopus 로고
    • Differential expression in rheumatoid synovium and synovial fluid of α4β7 integrin
    • LAZAROVITS A.I. & KARSH J. (1993) Differential expression in rheumatoid synovium and synovial fluid of α4β7 integrin. J Immunol 151, 6482.
    • (1993) J Immunol , vol.151 , pp. 6482
    • Lazarovits, A.I.1    Karsh, J.2
  • 47
    • 0028144871 scopus 로고
    • The role of tumor necrosis factor α and interleukin-1 in polymorphonuclear leukocyte and T-lymphocyte recruitment to joint inflammation in adjuvant arthritis
    • ISSEKUTZ A.C., MEAGER A., OTTERNESS I. & ISSEKUTZ T.B. (1994) The role of tumor necrosis factor α and interleukin-1 in polymorphonuclear leukocyte and T-lymphocyte recruitment to joint inflammation in adjuvant arthritis. Clin Exp Immunol 97, 26.
    • (1994) Clin Exp Immunol , vol.97 , pp. 26
    • Issekutz, A.C.1    Meager, A.2    Otterness, I.3    Issekutz, T.B.4
  • 48
    • 9344237564 scopus 로고
    • Effect of cyclosporin A on PMNL and T-lymphocyte migration to joints in adjuvant arthritis
    • Abstract
    • ISSEKUTZ A.C. & ISSEKUTZ T.B. (1994) Effect of cyclosporin A on PMNL and T-lymphocyte migration to joints in adjuvant arthritis. Canad J Physiol Pharmacol 72 S1, 266 (Abstract).
    • (1994) Canad J Physiol Pharmacol , vol.72 S1 , pp. 266
    • Issekutz, A.C.1    Issekutz, T.B.2
  • 49
    • 0026061858 scopus 로고
    • The mechanism of action of cyclosporine: A perspective for the 90's
    • HALLORAN P.F. & MADRENAS J. (1991) The mechanism of action of cyclosporine: a perspective for the 90's. Clin Biochem 24, 3.
    • (1991) Clin Biochem , vol.24 , pp. 3
    • Halloran, P.F.1    Madrenas, J.2
  • 50
    • 0026602739 scopus 로고
    • TNFα - A pivotal role in rheumatoid arthritis?
    • BRENNAN F.M., MAINI R.N. & FELDMANN M. (1992) TNFα - a pivotal role in rheumatoid arthritis? Br J Rheumatol 31, 293.
    • (1992) Br J Rheumatol , vol.31 , pp. 293
    • Brennan, F.M.1    Maini, R.N.2    Feldmann, M.3
  • 51
    • 0029071643 scopus 로고
    • Chemokines and tissue injury
    • FURIE M.B. & RANDOLPH G.J. (1995) Chemokines and tissue injury. Am J Pathol 146, 1287.
    • (1995) Am J Pathol , vol.146 , pp. 1287
    • Furie, M.B.1    Randolph, G.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.