메뉴 건너뛰기




Volumn 61, Issue 17, 2004, Pages 2168-2172

Gene silencing in DNA damage repair

Author keywords

Cancer; DNA methylation; DNA repair; Heterochromatin; Histone modification

Indexed keywords

DNA; HISTONE; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH3; PROTEIN MSH6; VON HIPPEL LINDAU PROTEIN;

EID: 4644229963     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-004-4178-9     Document Type: Review
Times cited : (11)

References (35)
  • 1
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch R. and Bird A. (2003) Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33: 245-254
    • (2003) Nat. Genet. , vol.33 , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 2
    • 0042528729 scopus 로고    scopus 로고
    • Heterochromatin and epigenetic control of gene expression
    • Grewal S. I. and Moazed D. (2003) Heterochromatin and epigenetic control of gene expression. Science 301: 798-802
    • (2003) Science , vol.301 , pp. 798-802
    • Grewal, S.I.1    Moazed, D.2
  • 3
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones P. A. and Laird P. W. (1999) Cancer epigenetics comes of age. Nat. Genet. 21: 163-167
    • (1999) Nat. Genet. , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 4
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P. A. and Baylin S. B. (2002) The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3: 415-428
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 5
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • Herman J. G. and Baylin S. B. (2003) Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 349: 2042-2054
    • (2003) N. Engl. J. Med. , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 6
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • Knudson A. G. Jr (1971) Mutation and cancer: statistical study of retinoblastoma. Proc. Natl. Acad. Sci. USA 68: 820-823
    • (1971) Proc. Natl. Acad. Sci. USA , vol.68 , pp. 820-823
    • Knudson Jr., A.G.1
  • 7
    • 0030739106 scopus 로고    scopus 로고
    • Molecular basis of HNPCC: Mutations of MMR genes
    • Papadopoulos N. and Lindblom A. (1997) Molecular basis of HNPCC: mutations of MMR genes. Human Mut. 10: 89-99
    • (1997) Human Mut. , vol.10 , pp. 89-99
    • Papadopoulos, N.1    Lindblom, A.2
  • 8
    • 13144266670 scopus 로고    scopus 로고
    • Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
    • Herman J. G., Umar A., Polyak K., Graff J. R., Ahuja N., Issa J. P. et al. (1998) Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc. Natl. Acad. Sci. USA 95: 6870-6875
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6870-6875
    • Herman, J.G.1    Umar, A.2    Polyak, K.3    Graff, J.R.4    Ahuja, N.5    Issa, J.P.6
  • 9
    • 0035870248 scopus 로고    scopus 로고
    • A gene hypermethylation profile of human cancer
    • Esteller M., Corn P. G., Baylin S. B. and Herman J. G. (2001) A gene hypermethylation profile of human cancer. Cancer Res. 61: 3225-3229
    • (2001) Cancer Res. , vol.61 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3    Herman, J.G.4
  • 11
    • 0035874892 scopus 로고    scopus 로고
    • 6- methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis
    • 6-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis. Cancer Res. 61: 4689-4692
    • (2001) Cancer Res. , vol.61 , pp. 4689-4692
    • Esteller, M.1    Risques, R.A.2    Toyota, M.3    Capella, G.4    Moreno, V.5    Peinado, M.A.6
  • 12
    • 0032706744 scopus 로고    scopus 로고
    • hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis
    • Esteller M., Catasus L., Matias-Guiu X., Mutter G. L., Prat J., Baylin S. B. et al. (1999) hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis. Am. J. Pathol. 155: 1767-1772
    • (1999) Am. J. Pathol. , vol.155 , pp. 1767-1772
    • Esteller, M.1    Catasus, L.2    Matias-Guiu, X.3    Mutter, G.L.4    Prat, J.5    Baylin, S.B.6
  • 14
    • 0034282793 scopus 로고    scopus 로고
    • Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1
    • Fleisher A. S., Esteller M., Harpaz N., Leytin A., Rashid A., Xu Y. et al. (2000) Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1. Cancer Res. 60: 4864-4868
    • (2000) Cancer Res. , vol.60 , pp. 4864-4868
    • Fleisher, A.S.1    Esteller, M.2    Harpaz, N.3    Leytin, A.4    Rashid, A.5    Xu, Y.6
  • 15
    • 0037115964 scopus 로고    scopus 로고
    • Gene silencing in phenomena related to DNA repair
    • Mukai T. and Sekiguchi M. (2002) Gene silencing in phenomena related to DNA repair. Oncogene 21: 9033-9042
    • (2002) Oncogene , vol.21 , pp. 9033-9042
    • Mukai, T.1    Sekiguchi, M.2
  • 16
    • 0032574814 scopus 로고    scopus 로고
    • Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes
    • Kawate H., Sakumi K., Tsuzuki T., Nakatsuru Y., Ishikawa T., Takahashi S. et al. (1998) Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes. Proc. Natl. Acad. Sci. USA 95: 5116-5120
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5116-5120
    • Kawate, H.1    Sakumi, K.2    Tsuzuki, T.3    Nakatsuru, Y.4    Ishikawa, T.5    Takahashi, S.6
  • 17
    • 0037463277 scopus 로고    scopus 로고
    • CpG methylation of MGMT and hMLH1 promoter in hepatocellular carcinoma associated with hepatitis viral infection
    • Matsukura S., Soejima H., Nakagawachi T., Yakushiji H., Ogawa A., Fukuhara M. et al. (2003) CpG methylation of MGMT and hMLH1 promoter in hepatocellular carcinoma associated with hepatitis viral infection. Br. J. Cancer 88: 521-529
    • (2003) Br. J. Cancer , vol.88 , pp. 521-529
    • Matsukura, S.1    Soejima, H.2    Nakagawachi, T.3    Yakushiji, H.4    Ogawa, A.5    Fukuhara, M.6
  • 19
    • 0037005988 scopus 로고    scopus 로고
    • Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma
    • Esteller M., Gaidano G., Goodman S. N., Zagonel V., Capello D., Botto B. et al. (2002) Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma. J. Natl. Cancer Inst. 94: 26-32
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 26-32
    • Esteller, M.1    Gaidano, G.2    Goodman, S.N.3    Zagonel, V.4    Capello, D.5    Botto, B.6
  • 21
    • 0036256948 scopus 로고    scopus 로고
    • Deficient expression of O(6)-methylguanine-DNA methyltransferase combined with mismatch-repair proteins hMLH1 and hMSH2 is related to poor prognosis in human biliary tract carcinoma
    • Kohya N., Miyazaki K., Matsukura S., Yakushiji H., Kitajima Y., Kitahara K. et al. (2002) Deficient expression of O(6)-methylguanine-DNA methyltransferase combined with mismatch-repair proteins hMLH1 and hMSH2 is related to poor prognosis in human biliary tract carcinoma. Ann. Surg. Oncol. 9: 371-379
    • (2002) Ann. Surg. Oncol. , vol.9 , pp. 371-379
    • Kohya, N.1    Miyazaki, K.2    Matsukura, S.3    Yakushiji, H.4    Kitajima, Y.5    Kitahara, K.6
  • 23
    • 0036494563 scopus 로고    scopus 로고
    • Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic Mice
    • Eads C. A., Nickel A. E. and Laird P. W. (2002) Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic Mice. Cancer Res. 62: 1296-1299
    • (2002) Cancer Res. , vol.62 , pp. 1296-1299
    • Eads, C.A.1    Nickel, A.E.2    Laird, P.W.3
  • 24
    • 18344390653 scopus 로고    scopus 로고
    • DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
    • Rhee I., Bachman K. E., Park B. H., Jair K. W., Yen R. W., Schuebel K. E. et al. (2002) DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 416: 552-556
    • (2002) Nature , vol.416 , pp. 552-556
    • Rhee, I.1    Bachman, K.E.2    Park, B.H.3    Jair, K.W.4    Yen, R.W.5    Schuebel, K.E.6
  • 25
    • 0034720284 scopus 로고    scopus 로고
    • CpG methylation is maintained in human cancer cells lacking DNMT1
    • Rhee I., Jair K. W., Yen R. W., Lengauer C., Herman J. G., Kinzler K. W. et al. (2000) CpG methylation is maintained in human cancer cells lacking DNMT1. Nature 404: 1003-1007
    • (2000) Nature , vol.404 , pp. 1003-1007
    • Rhee, I.1    Jair, K.W.2    Yen, R.W.3    Lengauer, C.4    Herman, J.G.5    Kinzler, K.W.6
  • 26
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T. and Allis C. D. (2001) Translating the histone code. Science 293: 1074-1080
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 27
    • 0036591878 scopus 로고    scopus 로고
    • The many faces of histone lysine methylation
    • Lachner M. and Jenuwein T. (2002) The many faces of histone lysine methylation. Curr. Opin. Cell Biol. 14: 286-298
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 286-298
    • Lachner, M.1    Jenuwein, T.2
  • 28
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • Tate P. H. and Bird A. P. (1993) Effects of DNA methylation on DNA-binding proteins and gene expression. Curr. Opin. Genet. Dev. 3: 226-231
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 226-231
    • Tate, P.H.1    Bird, A.P.2
  • 29
    • 0037591867 scopus 로고    scopus 로고
    • Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression
    • Fujita N., Watanabe S., Ichimura T., Tsuruzoe S., Shinkai Y., Tachibana M. et al. (2003) Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression. J. Biol. Chem. 278: 24132-24138
    • (2003) J. Biol. Chem. , vol.278 , pp. 24132-24138
    • Fujita, N.1    Watanabe, S.2    Ichimura, T.3    Tsuruzoe, S.4    Shinkai, Y.5    Tachibana, M.6
  • 30
    • 0037423186 scopus 로고    scopus 로고
    • The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation
    • Fuks F., Hurd P. J., Wolf D., Nan X., Bird A. P. and Kouzarides T. (2003) The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation. J. Biol. Chem. 278: 4035-4040
    • (2003) J. Biol. Chem. , vol.278 , pp. 4035-4040
    • Fuks, F.1    Hurd, P.J.2    Wolf, D.3    Nan, X.4    Bird, A.P.5    Kouzarides, T.6
  • 32
    • 0037115392 scopus 로고    scopus 로고
    • Dependence of histone modifications and gene expression on DNA hypermethylation in cancer
    • Fahrner J. A., Eguchi S., Herman J. G. and Baylin S. B. (2002) Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. Cancer Res. 62: 7213-7218
    • (2002) Cancer Res. , vol.62 , pp. 7213-7218
    • Fahrner, J.A.1    Eguchi, S.2    Herman, J.G.3    Baylin, S.B.4
  • 33
    • 0037215568 scopus 로고    scopus 로고
    • Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer
    • Kondo Y., Shen L. and Issa J. P. (2003) Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. Mol. Cell. Biol. 23: 206-215
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 206-215
    • Kondo, Y.1    Shen, L.2    Issa, J.P.3
  • 34
    • 0035891265 scopus 로고    scopus 로고
    • A histone H3 methyltransferase controls DNA methylation in Neurospora crassa
    • Tamaru H. and Selker E. U. (2001) A histone H3 methyltransferase controls DNA methylation in Neurospora crassa. Nature 414: 277-283
    • (2001) Nature , vol.414 , pp. 277-283
    • Tamaru, H.1    Selker, E.U.2
  • 35
    • 0037041422 scopus 로고    scopus 로고
    • Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase
    • Jackson J. P., Lindroth A. M., Cao X. and Jacobsen S. E. (2002) Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature 416: 556-560
    • (2002) Nature , vol.416 , pp. 556-560
    • Jackson, J.P.1    Lindroth, A.M.2    Cao, X.3    Jacobsen, S.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.