Isolation, cloning and structural characterization of boophilin, a multifunctional Kunitz-type proteinase inhibitor from the cattle tick

PLoS ONE

Volumn 3, Issue 2, 2008, Pages 1-17

  Macedo Ribeiro, Sandra ^a,b   Almeida, Carla ^a   Calisto, Bárbara M ^b,g   Friedrich, Thomas ^c   Mentele, Reinhard ^d   Stürzebecher, Jörg ^e   Fuentes Prior, Pablo ^f   Pereira, Pedro José Barbosa ^b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c BASF SE   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

^e Zentrum fur Vaskulare Biol und Med   (Germany)

^f Institut Català de Ciències Cardiovasculars   (Spain)

^g INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BOOPHILIN; PLASMIN; SERINE PROTEINASE INHIBITOR; THROMBIN; TRYPSIN; MULTIPROTEIN COMPLEX; PROTEINASE INHIBITOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BOOPHILUS MICROPLUS; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITION; ESCHERICHIA COLI; GENE OVEREXPRESSION; IN VIVO STUDY; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STEREOSPECIFICITY; ANIMAL; BINDING SITE; CATTLE; CHEMISTRY; ISOLATION AND PURIFICATION; METABOLISM; PROTEIN BINDING; TICK; X RAY CRYSTALLOGRAPHY;

ANIMALIA; BOOPHILUS MICROPLUS; BOVINAE; ESCHERICHIA COLI;

ANIMALS; BINDING SITES; CATTLE; CRYSTALLOGRAPHY, X-RAY; MULTIPROTEIN COMPLEXES; PROTEASE INHIBITORS; PROTEIN BINDING; THROMBIN; TICKS; TRYPSIN;

EID: 45849130590     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001624     Document Type: Article

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