The second Kunitz domain of human tissue factor pathway inhibitor: Cloning, structure determination and interaction with factor Xa

Journal of Molecular Biology

Volumn 269, Issue 3, 1997, Pages 395-407

  Burgering, Maurits J M ^a   Orbons, Leon P M ^a   Van Der Doelen, Antoon ^a   Mulders, John ^a   Theunissen, Henri J M ^a   Grootenhuis, Peter D J ^a   Bode, Wolfram ^b   Huber, Robert ^b   Stubbs, Milton T ^b  

^a NV ORGANON   (Netherlands)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

Blood coagulation; Kunitz type protease inhibitor; Nuclear magnetic resonance; Protein structure; X ray crystallography

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7A; GLYCOPROTEIN; TISSUE FACTOR PATHWAY INHIBITOR; TRYPSIN; TYROSINE;

AQUEOUS SOLUTION; ARTICLE; COMPARATIVE STUDY; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG DESIGN; ELECTRICITY; ESCHERICHIA COLI; GEL PERMEATION CHROMATOGRAPHY; HEMOSTASIS; ION EXCHANGE; MOLECULAR CLONING; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; R FACTOR; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI; SUIDAE;

EID: 0031566430     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.1029     Document Type: Article

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