Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin: Implications for KD1 specificity of inhibition

Journal of Biological Chemistry

Volumn 280, Issue 30, 2005, Pages 27832-27838

  Schmidt, Amy E ^a,b   Chand, Hitendra S ^c   Cascio, Dulio ^a   Kisiel, Walter ^c   Bajaj, S Paul ^a,b,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^d JOINT REPLACEMENT INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; ELECTROSTATICS; HYDROPHOBICITY; MOLECULES; TISSUE;

ELECTROSTATIC INTERACTIONS; HYDROPHOBIC INTERFACES; TISSUE FACTORS; WATER MOLECULES;

BIOCHEMISTRY;

APROTININ; ARGININE; CHYMOTRYPSIN; PLACENTA PROTEIN 5; PLASMIN; THROMBOPLASTIN; TRYPSIN; TYROSINE;

ANIMAL CELL; ARTICLE; COLLAGEN SYNTHESIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; HYDROPHOBICITY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS; TISSUE SPECIFICITY;

ANIMALS; CATTLE; CHYMOTRYPSIN; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; ESCHERICHIA COLI; FACTOR VIIA; GLYCOPROTEINS; HUMANS; LEUCINE; MODELS, MOLECULAR; NEOPLASM METASTASIS; OXYGEN; PHENYLALANINE; PLASMIN; PROTEASE INHIBITORS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SERINE; TRYPSIN;

BOVINAE;

EID: 23044502564     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M504105200     Document Type: Article

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