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Archiv der Pharmazie

Volumn 337, Issue 4, 2004, Pages 213-218

Non-thiol farnesyltransferase inhibitors: Utilization of the near aryl binding site by 5-arylacetylaminobenzophenones

(4) Mitsch, Andreas b Böhm, Markus b,c Sattler, Isabel d Schlitzer, Martin a

a UNIVERSITY OF MUNICH (Germany)

b PHILIPPS UNIVERSITY MARBURG (Germany)

c PFIZER INC (United States)

d BIOMATERIALS DEPARTMENT (Germany)

Author keywords

Aryl binding site; Non thiol farnesyltransferase inhibitors; Structure activity relationships

Indexed keywords

BENZOPHENONE DERIVATIVE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; ZINC ION; ENZYME INHIBITOR; FARNESYL TRANS TRANSFERASE; TRANSFERASE;

ARTICLE; CATALYSIS; DRUG BINDING SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; CHEMICAL STRUCTURE; DRUG ANTAGONISM; SYNTHESIS;

ALKYL AND ARYL TRANSFERASES; BENZOPHENONES; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4544239376 PISSN: 03656233 EISSN: None Source Type: Journal
DOI: 10.1002/ardp.200300843 Document Type: Article

Times cited : (4)

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