Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue

Biochemistry

Volumn 37, Issue 47, 1998, Pages 16601-16611

  Strickland, Corey L ^a   Windsor, William T ^a   Syto, Rosalinda ^a   Wang, Lynn ^a   Bond, Richard ^a   Wu, Zhen ^a   Schwartz, Jeffrey ^a   Le, Hung V ^a   Beese, Lorena S ^b   Weber, Patricia C ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GERANYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE; PYROPHOSPHATE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; RAT;

ALKYL AND ARYL TRANSFERASES; ANIMALS; BINDING SITES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; FARNESOL; HUMANS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; OLIGOPEPTIDES; PHOSPHONIC ACIDS; POLYISOPRENYL PHOSPHATES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; SUBSTRATE SPECIFICITY;

EID: 0032564385     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981197z     Document Type: Article

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