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Volumn 46, Issue 11, 2008, Pages 675-683

Inflammatory/anti-inflammatory mechanisms in the brain following exposure to stress;Mecanismos inflamatorios/antiinflamatorios en el cerebro tras la exposición a estrés

Author keywords

15d PGJ2; Catecholamines; Cytosines; Glucocorticoids; Glutamate; Neuroinflammation; PPAR gamma; Stress

Indexed keywords

CYTOSINE DERIVATIVE; FREE RADICAL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRIC OXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN SYNTHASE; STRESS HORMONE; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 45249083893     PISSN: 02100010     EISSN: None     Source Type: Journal    
DOI: 10.33588/rn.4611.2008073     Document Type: Article
Times cited : (9)

References (85)
  • 1
    • 2942687605 scopus 로고    scopus 로고
    • Elaborate interactions between the immune and nervous systems
    • Steinman L. Elaborate interactions between the immune and nervous systems. Nat Immunol 2004; 5: 575-81.
    • (2004) Nat Immunol , vol.5 , pp. 575-581
    • Steinman, L.1
  • 2
    • 26844433194 scopus 로고    scopus 로고
    • Antiinflammatory action of glucocorticoids -new mechanisms for old drugs
    • Rhen T, Cidlowski JA. Antiinflammatory action of glucocorticoids -new mechanisms for old drugs. N Engl J Med 2005; 353: 1711-23.
    • (2005) N Engl J Med , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 3
    • 34249007019 scopus 로고
    • A syndrome produced by diverse nocuous agents
    • Selye H. A syndrome produced by diverse nocuous agents. Nature 1936; 138: 32.
    • (1936) Nature , vol.138 , pp. 32
    • Selye, H.1
  • 4
    • 0027231058 scopus 로고
    • Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: Comparison to hippocampus and basal ganglia
    • Moghaddam B. Stress preferentially increases extraneuronal levels of excitatory amino acids in the prefrontal cortex: comparison to hippocampus and basal ganglia. J Neurochem 1993; 60: 1650-7.
    • (1993) J Neurochem , vol.60 , pp. 1650-1657
    • Moghaddam, B.1
  • 5
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • Lucas SM, Rothwell NJ, Gibson RM. The role of inflammation in CNS injury and disease. Br J Pharmacol 2006; 147 (Suppl 1): S232-40.
    • (2006) Br J Pharmacol , vol.147 , Issue.SUPPL. 1
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 6
    • 0036307544 scopus 로고    scopus 로고
    • Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity
    • Elenkov IJ, Chrousos GP. Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity. Ann N Y Acad Sci 2002; 966: 290-303.
    • (2002) Ann N Y Acad Sci , vol.966 , pp. 290-303
    • Elenkov, I.J.1    Chrousos, G.P.2
  • 7
    • 0036911319 scopus 로고    scopus 로고
    • Stress and the inflammatory response: A review of neurogenic inflammation
    • Black PH. Stress and the inflammatory response: a review of neurogenic inflammation. Brain Behav Immun 2002; 16: 622-53.
    • (2002) Brain Behav Immun , vol.16 , pp. 622-653
    • Black, P.H.1
  • 8
    • 0042731701 scopus 로고    scopus 로고
    • Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons
    • Klotz L, Sastre M, Kreutz A, Gavrilyuk V, Klockgether T, Feinstein DL, et al. Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. J Neurochem 2003; 86: 907-16.
    • (2003) J Neurochem , vol.86 , pp. 907-916
    • Klotz, L.1    Sastre, M.2    Kreutz, A.3    Gavrilyuk, V.4    Klockgether, T.5    Feinstein, D.L.6
  • 9
    • 33846661385 scopus 로고    scopus 로고
    • An inflammatory review of glucocorticoid actions in the CNS
    • Sorrells SF, Sapolsky RM. An inflammatory review of glucocorticoid actions in the CNS. Brain Behav Immun 2006; 21: 259-272.
    • (2006) Brain Behav Immun , vol.21 , pp. 259-272
    • Sorrells, S.F.1    Sapolsky, R.M.2
  • 10
    • 0034049874 scopus 로고    scopus 로고
    • Glucocorticoids in T cell development and function
    • Ashwell JD, Lu FW, Vacchio MS. Glucocorticoids in T cell development and function. Annu Rev Immunol 2000; 18: 309-45.
    • (2000) Annu Rev Immunol , vol.18 , pp. 309-345
    • Ashwell, J.D.1    Lu, F.W.2    Vacchio, M.S.3
  • 11
    • 0034464826 scopus 로고    scopus 로고
    • CBP (CREB binding protein) integrates NF-kappaB (nuclear factor-kappaB) and glucocorticoid receptor physical interactions and antagonism
    • McKay LI, Cidlowski JA. CBP (CREB binding protein) integrates NF-kappaB (nuclear factor-kappaB) and glucocorticoid receptor physical interactions and antagonism. Mol Endocrinol 2000; 14: 1222-34.
    • (2000) Mol Endocrinol , vol.14 , pp. 1222-1234
    • McKay, L.I.1    Cidlowski, J.A.2
  • 12
    • 0030318063 scopus 로고    scopus 로고
    • Stress, glucocorticoids, and damage to the nervous system: The current state of confusion
    • Sapolsky RM. Stress, glucocorticoids, and damage to the nervous system: the current state of confusion. Stress 1996; 1: 1-19.
    • (1996) Stress , vol.1 , pp. 1-19
    • Sapolsky, R.M.1
  • 13
    • 0028133260 scopus 로고
    • Physiological elevations of glucocorticoids potentiate glutamate accumulation in the hippocampus
    • Stein-Behrens BA, Lin WJ, Sapolsky RM. Physiological elevations of glucocorticoids potentiate glutamate accumulation in the hippocampus. J Neurochem 1994 63: 596-602.
    • (1994) J Neurochem , vol.63 , pp. 596-602
    • Stein-Behrens, B.A.1    Lin, W.J.2    Sapolsky, R.M.3
  • 14
    • 33645566358 scopus 로고    scopus 로고
    • Chronic unpredictable stress exacerbates lipopolysaccharide-induced activation of nuclear factor-kappaB in the frontal cortex and hippocampus via glucocorticoid secretion
    • Munhoz CD, Lepsch LB, Kawamoto EM, Malta MB, De Sá-Lima L, Avellar MC, et al. Chronic unpredictable stress exacerbates lipopolysaccharide-induced activation of nuclear factor-kappaB in the frontal cortex and hippocampus via glucocorticoid secretion. J Neurosci 2006; 26: 3813-20.
    • (2006) J Neurosci , vol.26 , pp. 3813-3820
    • Munhoz, C.D.1    Lepsch, L.B.2    Kawamoto, E.M.3    Malta, M.B.4    De Sá-Lima, L.5    Avellar, M.C.6
  • 15
    • 0037312860 scopus 로고    scopus 로고
    • Novel glucocorticoid effects on acute inflammation in the CNS
    • Dinkel K, MacPherson A, Sapolsky RM. Novel glucocorticoid effects on acute inflammation in the CNS. J Neurochem 2003; 84: 705-16.
    • (2003) J Neurochem , vol.84 , pp. 705-716
    • Dinkel, K.1    MacPherson, A.2    Sapolsky, R.M.3
  • 16
    • 22044446806 scopus 로고    scopus 로고
    • Glucocorticoids worsen excitotoxin-induced expression of pro-inflammatory cytokines in hippocampal cultures
    • MacPherson A, Dinkel K, Sapolsky RM. Glucocorticoids worsen excitotoxin-induced expression of pro-inflammatory cytokines in hippocampal cultures. Exp Neurol 2005; 194: 376-83.
    • (2005) Exp Neurol , vol.194 , pp. 376-383
    • MacPherson, A.1    Dinkel, K.2    Sapolsky, R.M.3
  • 17
    • 0032797940 scopus 로고    scopus 로고
    • Glucocorticoids stimulate inflammatory 5-lipoxygenase gene expression and protein translocation in the brain
    • Uz T, Dwivedi Y, Savani PD, Impagnatiello F, Pandey G, Manev H. Glucocorticoids stimulate inflammatory 5-lipoxygenase gene expression and protein translocation in the brain. J Neurochem 1999; 73: 693-9.
    • (1999) J Neurochem , vol.73 , pp. 693-699
    • Uz, T.1    Dwivedi, Y.2    Savani, P.D.3    Impagnatiello, F.4    Pandey, G.5    Manev, H.6
  • 18
    • 29244481976 scopus 로고    scopus 로고
    • Stress-induced elevation of glucocorticoids increases microglia proliferation through NMDA receptor activation
    • Nair A, Bonneau RH. Stress-induced elevation of glucocorticoids increases microglia proliferation through NMDA receptor activation. J Neuroimmunol 2006; 171: 72-85.
    • (2006) J Neuroimmunol , vol.171 , pp. 72-85
    • Nair, A.1    Bonneau, R.H.2
  • 20
    • 0023921318 scopus 로고
    • Adrenocorticotropin release induced by intracerebroventricular injection of recombinant human interleukin-1 in rats possible involvement of prostaglandin
    • Katsuura G, Gottschall PE, Dahl RR, Arimura A. Adrenocorticotropin release induced by intracerebroventricular injection of recombinant human interleukin-1 in rats possible involvement of prostaglandin. Endocrinology 1988; 122: 1773-9.
    • (1988) Endocrinology , vol.122 , pp. 1773-1779
    • Katsuura, G.1    Gottschall, P.E.2    Dahl, R.R.3    Arimura, A.4
  • 21
    • 0034062158 scopus 로고    scopus 로고
    • Cytokines and the brain implications for clinical psychiatry
    • Kronfol Z, Remick DG. Cytokines and the brain implications for clinical psychiatry. Am J Psychiatry 2000; 157: 683-94.
    • (2000) Am J Psychiatry , vol.157 , pp. 683-694
    • Kronfol, Z.1    Remick, D.G.2
  • 22
    • 0037643307 scopus 로고    scopus 로고
    • The role of the cytokine network in psychological stress
    • Kim YK, Maes M. The role of the cytokine network in psychological stress. Acta Neuropsychiatrica 2003; 15: 148-55.
    • (2003) Acta Neuropsychiatrica , vol.15 , pp. 148-155
    • Kim, Y.K.1    Maes, M.2
  • 23
    • 0032423321 scopus 로고    scopus 로고
    • Glucocorticoid-induced type 1/type 2 cytokine alterations in humans: A model for stress- related immune dysfunction
    • Agarwal SK, Marshall GD Jr. Glucocorticoid-induced type 1/type 2 cytokine alterations in humans: a model for stress- related immune dysfunction. J Interferon Cytokine Res 1998; 18: 1059-68.
    • (1998) J Interferon Cytokine Res , vol.18 , pp. 1059-1068
    • Agarwal, S.K.1    Marshall Jr., G.D.2
  • 24
    • 0442272538 scopus 로고    scopus 로고
    • When not enough is too much: The role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders
    • Raison CL, Miller AH. When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders. Am J Psychiatry 2003; 160: 1554-65.
    • (2003) Am J Psychiatry , vol.160 , pp. 1554-1565
    • Raison, C.L.1    Miller, A.H.2
  • 25
    • 0033282371 scopus 로고    scopus 로고
    • Effects of cytokines on cerebral neurotransmission. Comparison with the effects of stress
    • Dunn AJ, Wang J, Ando T. Effects of cytokines on cerebral neurotransmission. Comparison with the effects of stress. Adv Exp Med Biol 1999; 461: 117-27.
    • (1999) Adv Exp Med Biol , vol.461 , pp. 117-127
    • Dunn, A.J.1    Wang, J.2    Ando, T.3
  • 26
    • 0009466560 scopus 로고    scopus 로고
    • Induction of cytokine receptors by glucocorticoids: Functional and pathological significance
    • Wiegers GJ, Reul JM. Induction of cytokine receptors by glucocorticoids: functional and pathological significance. Trends Pharmacol Sci 1998; 19: 317-21.
    • (1998) Trends Pharmacol Sci , vol.19 , pp. 317-321
    • Wiegers, G.J.1    Reul, J.M.2
  • 27
    • 0036063103 scopus 로고    scopus 로고
    • Involvement of inflammatory cytokines in central nervous system injury
    • Wang CX, Shuaib A. Involvement of inflammatory cytokines in central nervous system injury. Prog Neurobiol 2002; 67: 161-72.
    • (2002) Prog Neurobiol , vol.67 , pp. 161-172
    • Wang, C.X.1    Shuaib, A.2
  • 28
    • 0036148669 scopus 로고    scopus 로고
    • The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress
    • Madrigal JL, Hurtado O, Moro MA, Lizasoain I, Lorenzo P, Castrillo A, et al. The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress. Neuropsychopharmacology 2002; 26: 155-63.
    • (2002) Neuropsychopharmacology , vol.26 , pp. 155-163
    • Madrigal, J.L.1    Hurtado, O.2    Moro, M.A.3    Lizasoain, I.4    Lorenzo, P.5    Castrillo, A.6
  • 29
    • 0034986981 scopus 로고    scopus 로고
    • Up-regulation of TNFa convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices
    • Hurtado O, Cárdenas A, Lizasoain I, Boscá L, Leza JC, Lorenzo P, et al. Up-regulation of TNFa convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices. Neuropharmacology 2001; 40: 1094-102.
    • (2001) Neuropharmacology , vol.40 , pp. 1094-1102
    • Hurtado, O.1    Cárdenas, A.2    Lizasoain, I.3    Boscá, L.4    Leza, J.C.5    Lorenzo, P.6
  • 30
    • 0034534995 scopus 로고    scopus 로고
    • Interleukin 1 in the brain: Biology, pathology and therapeutic target
    • Rothwell NJ, Luheshi GN. Interleukin 1 in the brain: biology, pathology and therapeutic target. Trends Neurosci 2000; 23: 618-25.
    • (2000) Trends Neurosci , vol.23 , pp. 618-625
    • Rothwell, N.J.1    Luheshi, G.N.2
  • 31
    • 0032521115 scopus 로고    scopus 로고
    • Exposure to acute stress induces brain interleukin-1beta protein in the rat
    • Nguyen KT, Deak T, Owens SM, Kohno T, Fleshner M, Watkins LR, et al. Exposure to acute stress induces brain interleukin-1beta protein in the rat. J Neurosci 1998; 18: 2239-46.
    • (1998) J Neurosci , vol.18 , pp. 2239-2246
    • Nguyen, K.T.1    Deak, T.2    Owens, S.M.3    Kohno, T.4    Fleshner, M.5    Watkins, L.R.6
  • 33
    • 0031600021 scopus 로고    scopus 로고
    • Cytokines for psychologists: Implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition
    • Maier SF, Watkins LR. Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition. Psychol Rev 1998; 105: 83-107.
    • (1998) Psychol Rev , vol.105 , pp. 83-107
    • Maier, S.F.1    Watkins, L.R.2
  • 34
    • 26244440570 scopus 로고    scopus 로고
    • Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines
    • Johnson JD, Campisi J, Sharkey CM, Kennedy SL, Nickerson M, Greenwood BN, et al. Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines. Neuroscience 2005; 135: 1295-307.
    • (2005) Neuroscience , vol.135 , pp. 1295-1307
    • Johnson, J.D.1    Campisi, J.2    Sharkey, C.M.3    Kennedy, S.L.4    Nickerson, M.5    Greenwood, B.N.6
  • 35
    • 0030058649 scopus 로고    scopus 로고
    • Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: A study on IL-6-deficient mice
    • Chai Z, Gatti S, Toniatti C, Poli V, Bartfai T. Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice. J Exp Med 1996; 183: 311-6.
    • (1996) J Exp Med , vol.183 , pp. 311-316
    • Chai, Z.1    Gatti, S.2    Toniatti, C.3    Poli, V.4    Bartfai, T.5
  • 36
    • 0028543542 scopus 로고
    • Immobilization stress may increase plasma interleukin 6 via central and peripheral catecholamines
    • Takaki A, Huang QH, Somogyvari-Vigh A, Arimura A. Immobilization stress may increase plasma interleukin 6 via central and peripheral catecholamines. Neuroimmunomodulation 1994; 1: 335-42.
    • (1994) Neuroimmunomodulation , vol.1 , pp. 335-342
    • Takaki, A.1    Huang, Q.H.2    Somogyvari-Vigh, A.3    Arimura, A.4
  • 38
    • 0035012146 scopus 로고    scopus 로고
    • Mechanisms and mediators of psychological stress-induced rise in core temperature
    • Oka T, Oka K, Hori T. Mechanisms and mediators of psychological stress-induced rise in core temperature. Psychosom Med 2001; 63: 476-86.
    • (2001) Psychosom Med , vol.63 , pp. 476-486
    • Oka, T.1    Oka, K.2    Hori, T.3
  • 39
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa-B proteins: New discoveries and insights
    • Baldwin AS Jr. The NF-kappa B and I kappa-B proteins: new discoveries and insights. Annu Rev Immunol 1996; 14: 649-83.
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 40
    • 0035143678 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor kappaB-mediated mechanisms
    • Madrigal JL, Moro MA, Lizasoain I, Lorenzo P, Castrillo A, Boscá L, et al. Inducible nitric oxide synthase expression in brain cortex after acute restraint stress is regulated by nuclear factor kappaB-mediated mechanisms. J Neurochem 2001; 76: 532-8.
    • (2001) J Neurochem , vol.76 , pp. 532-538
    • Madrigal, J.L.1    Moro, M.A.2    Lizasoain, I.3    Lorenzo, P.4    Castrillo, A.5    Boscá, L.6
  • 42
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43: 109-42.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 43
    • 0028922422 scopus 로고
    • Nitric oxide: Pathophysiological mechanisms
    • Gross SS, Wolin MS. Nitric oxide: pathophysiological mechanisms. Annu Rev Physiol 1995; 57: 737-69.
    • (1995) Annu Rev Physiol , vol.57 , pp. 737-769
    • Gross, S.S.1    Wolin, M.S.2
  • 44
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls, and controls
    • Nathan C, Xie QW. Nitric oxide synthases: roles, tolls, and controls. Cell 1994; 78: 915-8.
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.W.2
  • 46
    • 0027207985 scopus 로고
    • NOS mRNA in the paraventricular nucleus of young and old rats after immobilization stress
    • Calza L, Giardino L, Ceccatelli S. NOS mRNA in the paraventricular nucleus of young and old rats after immobilization stress. Neuroreport 1993; 4: 627-30.
    • (1993) Neuroreport , vol.4 , pp. 627-630
    • Calza, L.1    Giardino, L.2    Ceccatelli, S.3
  • 47
    • 0027226328 scopus 로고
    • Effects of repeated stress on plasma arginine levels in young and old rats
    • Milakofsky L, Harris N, Vogel WH. Effects of repeated stress on plasma arginine levels in young and old rats. Physiol Behav 1993; 54: 725-8.
    • (1993) Physiol Behav , vol.54 , pp. 725-728
    • Milakofsky, L.1    Harris, N.2    Vogel, W.H.3
  • 48
    • 0033958105 scopus 로고    scopus 로고
    • Chronic stress induces the expression of inducible nitric oxide synthase in rat brain cortex
    • Olivenza, R, Moro MA, Lizasoain I, Lorenzo P, Fernández AP, Rodrigo J, et al. Chronic stress induces the expression of inducible nitric oxide synthase in rat brain cortex. J Neurochem 2000; 74: 785-91.
    • (2000) J Neurochem , vol.74 , pp. 785-791
    • Olivenza, R.1    Moro, M.A.2    Lizasoain, I.3    Lorenzo, P.4    Fernández, A.P.5    Rodrigo, J.6
  • 49
    • 0037205158 scopus 로고    scopus 로고
    • Stress-induced increase in extracellular sucrose space in rats is mediated by nitric oxide
    • Madrigal JL, Moro MA, Lizasoain I, Lorenzo P, Leza JC. Stress-induced increase in extracellular sucrose space in rats is mediated by nitric oxide. Brain Res 2002; 938: 87-91.
    • (2002) Brain Res , vol.938 , pp. 87-91
    • Madrigal, J.L.1    Moro, M.A.2    Lizasoain, I.3    Lorenzo, P.4    Leza, J.C.5
  • 50
    • 0035132510 scopus 로고    scopus 로고
    • Glutathione depletion, lipid peroxidation and mitochondrial dysfunction are induced by chronic stress in rat brain
    • Madrigal JL, Olivenza R, Moro MA, Lizasoain I, Lorenzo P, Rodrigo P, et al. Glutathione depletion, lipid peroxidation and mitochondrial dysfunction are induced by chronic stress in rat brain. Neuropsychopharmacology 2001; 24: 420-29.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 420-429
    • Madrigal, J.L.1    Olivenza, R.2    Moro, M.A.3    Lizasoain, I.4    Lorenzo, P.5    Rodrigo, P.6
  • 51
    • 0030992849 scopus 로고    scopus 로고
    • Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase A2
    • Miettinen S, Fusco FR, Yrjanheikki J, Keinanen R, Hirvonen T, Roivainen R, et al. Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase A2. Proc Natl Acad Sci U S A 1997; 94: 6500-5.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 6500-6505
    • Miettinen, S.1    Fusco, F.R.2    Yrjanheikki, J.3    Keinanen, R.4    Hirvonen, T.5    Roivainen, R.6
  • 52
    • 0030909616 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage
    • Nogawa S, Zhang F, Ross ME, Iadecola C. Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage. J Neurosci 1997; 17: 2746-55.
    • (1997) J Neurosci , vol.17 , pp. 2746-2755
    • Nogawa, S.1    Zhang, F.2    Ross, M.E.3    Iadecola, C.4
  • 53
    • 0032190264 scopus 로고    scopus 로고
    • Cyclooxygenase and inflammation in Alzheimer's disease: Experimental approaches and clinical interventions
    • Pasinetti GM. Cyclooxygenase and inflammation in Alzheimer's disease: experimental approaches and clinical interventions. J Neurosci Res 1998; 54: 1-6.
    • (1998) J Neurosci Res , vol.54 , pp. 1-6
    • Pasinetti, G.M.1
  • 54
    • 0034799564 scopus 로고    scopus 로고
    • Cyclooxyge nase-2 inhibitor ns-398 protects neuronal cultures from lipopolysaccharide-induced neurotoxicity
    • Araki E, Forster C, Dubinsky JM, Ross ME, Iadecola C. Cyclooxyge nase-2 inhibitor ns-398 protects neuronal cultures from lipopolysaccharide-induced neurotoxicity. Stroke 2001; 32: 2370-5.
    • (2001) Stroke , vol.32 , pp. 2370-2375
    • Araki, E.1    Forster, C.2    Dubinsky, J.M.3    Ross, M.E.4    Iadecola, C.5
  • 55
    • 0037059399 scopus 로고    scopus 로고
    • Prostaglandin E(2) induces caspase-dependent apoptosis in rat cortical cells
    • Takadera T, Yumoto H, Tozuka Y, Ohyashiki T. Prostaglandin E(2) induces caspase-dependent apoptosis in rat cortical cells. Neurosci Lett 2002; 317: 61-4.
    • (2002) Neurosci Lett , vol.317 , pp. 61-64
    • Takadera, T.1    Yumoto, H.2    Tozuka, Y.3    Ohyashiki, T.4
  • 56
    • 0017091041 scopus 로고
    • Mechanism for irreversible self-deactivation of prostaglandin synthetase
    • Egan RW, Paxton J, Kuehl FA Jr. Mechanism for irreversible self-deactivation of prostaglandin synthetase. J Biol Chem 1976; 251: 7329-35.
    • (1976) J Biol Chem , vol.251 , pp. 7329-7335
    • Egan, R.W.1    Paxton, J.2    Kuehl Jr., F.A.3
  • 57
    • 0027290813 scopus 로고
    • Expression of a mitogen-inducible cyclooxygenase in brain neurones: Regulation by synaptic activity and glucocorticoids
    • Yamagata K, Andreasson KI, Kaufmann WE, Barnes CA, Worley PF. Expression of a mitogen-inducible cyclooxygenase in brain neurones: regulation by synaptic activity and glucocorticoids. Neuron 1993; 11: 371-86.
    • (1993) Neuron , vol.11 , pp. 371-386
    • Yamagata, K.1    Andreasson, K.I.2    Kaufmann, W.E.3    Barnes, C.A.4    Worley, P.F.5
  • 58
    • 0141957340 scopus 로고    scopus 로고
    • Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats
    • Katafuchi T, Takaki A, Take S, Kondo T, Yoshimura M. Endotoxin inhibitor blocks heat exposure-induced expression of brain cytokine mRNA in aged rats. Brain Res Mol Brain Res 2003; 118: 24-32.
    • (2003) Brain Res Mol Brain Res , vol.118 , pp. 24-32
    • Katafuchi, T.1    Takaki, A.2    Take, S.3    Kondo, T.4    Yoshimura, M.5
  • 59
    • 9244233792 scopus 로고    scopus 로고
    • Cyclooxygenase 2, pS2, inducible nitric oxid-e synthase and transforming growth factor alpha in gastric adaptation to stress
    • Nie SN, Sun HC, Wu XH, Qian XM. Cyclooxygenase 2, pS2, inducible nitric oxid-e synthase and transforming growth factor alpha in gastric adaptation to stress. World J Gastroenterol 2004; 10: 3537-41.
    • (2004) World J Gastroenterol , vol.10 , pp. 3537-3541
    • Nie, S.N.1    Sun, H.C.2    Wu, X.H.3    Qian, X.M.4
  • 63
    • 33646590972 scopus 로고    scopus 로고
    • Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic inflammatory response syndrome
    • Zacharowski K, Zacharowski PA, Koch A, Baban A, Tran N, Berkels R, et al. Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic inflammatory response syndrome. Proc Natl Acad Sci U S A 2006; 103: 6392-7.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 6392-6397
    • Zacharowski, K.1    Zacharowski, P.A.2    Koch, A.3    Baban, A.4    Tran, N.5    Berkels, R.6
  • 64
    • 0032518022 scopus 로고    scopus 로고
    • Protective and damaging effects of stress mediators
    • McEwen BS. Protective and damaging effects of stress mediators. N Engl J Med 1998; 338: 171-9.
    • (1998) N Engl J Med , vol.338 , pp. 171-179
    • McEwen, B.S.1
  • 65
    • 0037272881 scopus 로고    scopus 로고
    • Therapeutic potential of peroxisome proliferator-activated receptor agonists for neurological disease
    • Feinstein DL. Therapeutic potential of peroxisome proliferator-activated receptor agonists for neurological disease. Diabetes Technol Ther 2003; 5: 67-73.
    • (2003) Diabetes Technol Ther , vol.5 , pp. 67-73
    • Feinstein, D.L.1
  • 66
    • 0036010783 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma (PPARgamma) and its ligands: A review
    • Houseknecht KL, Cole BM, Steele PJ. Peroxisome proliferator-activated receptor gamma (PPARgamma) and its ligands: a review. Domest Anim Endocrinol 2002; 22: 1-23.
    • (2002) Domest Anim Endocrinol , vol.22 , pp. 1-23
    • Houseknecht, K.L.1    Cole, B.M.2    Steele, P.J.3
  • 67
    • 0030952937 scopus 로고    scopus 로고
    • Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta
    • Forman BM, Chen J, Evans RM. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proc Natl Acad Sci U S A 1997; 94: 4312-7.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 4312-4317
    • Forman, B.M.1    Chen, J.2    Evans, R.M.3
  • 68
    • 0028587764 scopus 로고
    • Localization of the peroxisome proliferator-activated receptor in the brain
    • Kainu T, Wikstrom AC, Gustafsson JA, Pelto-Huikko M. Localization of the peroxisome proliferator-activated receptor in the brain. Neuroreport 1994; 5: 2481-5.
    • (1994) Neuroreport , vol.5 , pp. 2481-2485
    • Kainu, T.1    Wikstrom, A.C.2    Gustafsson, J.A.3    Pelto-Huikko, M.4
  • 69
    • 20444398490 scopus 로고    scopus 로고
    • Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator- activated receptor gamma activation
    • Luna-Medina R, Cortes-Canteli M, Alonso M, Santos A, Martínez A, Pérez-Castillo A. Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator- activated receptor gamma activation. J Biol Chem 2005; 280: 21453-62.
    • (2005) J Biol Chem , vol.280 , pp. 21453-21462
    • Luna-Medina, R.1    Cortes-Canteli, M.2    Alonso, M.3    Santos, A.4    Martínez, A.5    Pérez-Castillo, A.6
  • 70
    • 16844374020 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma activation decreases neuroinflammation in brain after stress in rats
    • García-Bueno B, Madrigal JL, Lizasoain I, Moro MA, Lorenzo P, Leza JC. Peroxisome proliferator-activated receptor gamma activation decreases neuroinflammation in brain after stress in rats. Biol Psychiatry 2005; 57: 885-94.
    • (2005) Biol Psychiatry , vol.57 , pp. 885-894
    • García-Bueno, B.1    Madrigal, J.L.2    Lizasoain, I.3    Moro, M.A.4    Lorenzo, P.5    Leza, J.C.6
  • 71
    • 16844368096 scopus 로고    scopus 로고
    • The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/ nitrosative mediators in brain after acute stress in rats
    • García-Bueno B, Madrigal JL, Lizasoain I, Moro MA, Lorenzo P, Leza JC. The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/ nitrosative mediators in brain after acute stress in rats. Psychopharmacology (Berl) 2005; 180: 513-22.
    • (2005) Psychopharmacology (Berl) , vol.180 , pp. 513-522
    • García-Bueno, B.1    Madrigal, J.L.2    Lizasoain, I.3    Moro, M.A.4    Lorenzo, P.5    Leza, J.C.6
  • 72
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998; 391: 79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 73
    • 0033378706 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine induced apoptotic cell death by inhibition of inducible nitric oxide synthase
    • Heneka MT, Feinstein DL, Galea E, Gleichmann M, Wullner U, Klockgether T. Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine induced apoptotic cell death by inhibition of inducible nitric oxide synthase. J Neuroimmunol 1999; 100: 156-68.
    • (1999) J Neuroimmunol , vol.100 , pp. 156-168
    • Heneka, M.T.1    Feinstein, D.L.2    Galea, E.3    Gleichmann, M.4    Wullner, U.5    Klockgether, T.6
  • 74
    • 34249071696 scopus 로고    scopus 로고
    • Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats
    • García-Bueno B, Caso JR, Pérez-Nievas BG, Lorenzo P, Leza JC. Effects of peroxisome proliferator-activated receptor gamma agonists on brain glucose and glutamate transporters after stress in rats. Neuropsychopharmacology 2007; 32: 1251-60.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 1251-1260
    • García-Bueno, B.1    Caso, J.R.2    Pérez-Nievas, B.G.3    Lorenzo, P.4    Leza, J.C.5
  • 75
    • 0033622133 scopus 로고    scopus 로고
    • Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxydelta(12,14)-prostaglandin J(2) in activated murine macrophages
    • Castrillo A, Díaz-Guerra MJ, Hortelano S, Martín-Sanz P, Boscá L. Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxydelta(12,14)-prostaglandin J(2) in activated murine macrophages. Mol Cell Biol 2000; 20: 1692-8.
    • (2000) Mol Cell Biol , vol.20 , pp. 1692-1698
    • Castrillo, A.1    Díaz-Guerra, M.J.2    Hortelano, S.3    Martín-Sanz, P.4    Boscá, L.5
  • 76
    • 0035341427 scopus 로고    scopus 로고
    • Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma
    • Niino M, Iwabuchi K, Kikuchi S, Ato M, Morohashi T, Ogata A, et al. Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma. J Neuroimmunol 2001; 116: 40-8.
    • (2001) J Neuroimmunol , vol.116 , pp. 40-48
    • Niino, M.1    Iwabuchi, K.2    Kikuchi, S.3    Ato, M.4    Morohashi, T.5    Ogata, A.6
  • 77
    • 0036326074 scopus 로고    scopus 로고
    • Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease
    • Breidert T, Callebert J, Heneka MT, Landreth G, Launay JM, Hirsch EC. Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease. J Neurochem 2002; 82: 615-24.
    • (2002) J Neurochem , vol.82 , pp. 615-624
    • Breidert, T.1    Callebert, J.2    Heneka, M.T.3    Landreth, G.4    Launay, J.M.5    Hirsch, E.C.6
  • 78
    • 10044289268 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma ligands reduce inflammation and infarction size in transient focal ischemia
    • Sundararajan S, Gamboa JL, Victor NA, Wanderi EW, Lust WD, Landreth GE. Peroxisome proliferator-activated receptor-gamma ligands reduce inflammation and infarction size in transient focal ischemia. Neuroscience 2005; 130: 685-96.
    • (2005) Neuroscience , vol.130 , pp. 685-696
    • Sundararajan, S.1    Gamboa, J.L.2    Victor, N.A.3    Wanderi, E.W.4    Lust, W.D.5    Landreth, G.E.6
  • 79
    • 31444445868 scopus 로고    scopus 로고
    • Rosiglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2) cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms
    • Pereira MP, Hurtado O, Cárdenas A, Boscá L, Castillo J, Dávalos A, et al. Rosiglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2) cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms. J Cereb Blood Flow Metab 2006; 26: 218-29.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 218-229
    • Pereira, M.P.1    Hurtado, O.2    Cárdenas, A.3    Boscá, L.4    Castillo, J.5    Dávalos, A.6
  • 80
    • 20444363048 scopus 로고    scopus 로고
    • Increased plasma levels of 15-deoxydelta prostaglandin J2 are associated with good outcome in acute atherothrombotic ischemic stroke
    • Blanco M, Moro MA, Dávalos A, Leira R, Castellanos M, Serena J, et al. Increased plasma levels of 15-deoxydelta prostaglandin J2 are associated with good outcome in acute atherothrombotic ischemic stroke. Stroke 2005; 36: 1189-94.
    • (2005) Stroke , vol.36 , pp. 1189-1194
    • Blanco, M.1    Moro, M.A.2    Dávalos, A.3    Leira, R.4    Castellanos, M.5    Serena, J.6
  • 81
    • 0034651101 scopus 로고    scopus 로고
    • Inflammatory mechanisms in Alzheimer's disease: Inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists
    • Combs CK, Johnson DE, Karlo JC, Cannady SB, Landreth GE. Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists. J Neurosci 2000; 20: 558-67.
    • (2000) J Neurosci , vol.20 , pp. 558-567
    • Combs, C.K.1    Johnson, D.E.2    Karlo, J.C.3    Cannady, S.B.4    Landreth, G.E.5
  • 82
    • 20444499367 scopus 로고    scopus 로고
    • Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice
    • Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, et al. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain 2005; 128
    • (2005) Brain , pp. 128
    • Heneka, M.T.1    Sastre, M.2    Dumitrescu-Ozimek, L.3    Hanke, A.4    Dewachter, I.5    Kuiperi, C.6
  • 83
    • 20444499367 scopus 로고    scopus 로고
    • Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice
    • Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, et al. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain 2005; 128: 1442-53.
    • (2005) Brain , vol.128 , pp. 1442-1453
    • Heneka, M.T.1    Sastre, M.2    Dumitrescu-Ozimek, L.3    Hanke, A.4    Dewachter, I.5    Kuiperi, C.6


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