-
1
-
-
0024467154
-
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
-
Kobayashi, M., L. Fitz, M. Ryan, R.M. Hewick, S.C. Clark, S. Chan, R. Loudon, F. Sherman, B. Perussia, and G. Trinchieri. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J. Exp. Med. 170:827-846.
-
(1989)
J. Exp. Med
, vol.170
, pp. 827-846
-
-
Kobayashi, M.1
Fitz, L.2
Ryan, M.3
Hewick, R.M.4
Clark, S.C.5
Chan, S.6
Loudon, R.7
Sherman, F.8
Perussia, B.9
Trinchieri, G.10
-
2
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann, B., R. Lesley, B. Blom, J.C. Timans, Y. Xu, B. Hunte, F. Vega, N. Yu, J. Wang, K. Singh, et al. 2000. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity. 13:715-725.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
Vega, F.7
Yu, N.8
Wang, J.9
Singh, K.10
-
3
-
-
33845606612
-
IL-12p40: An inherently agonistic cytokine
-
Cooper, A.M., and S.A. Khader. 2007. IL-12p40: an inherently agonistic cytokine. Trends Immunol. 28:33-38.
-
(2007)
Trends Immunol
, vol.28
, pp. 33-38
-
-
Cooper, A.M.1
Khader, S.A.2
-
4
-
-
0026701132
-
Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells
-
D'Andrea, A., M. Rengaraju, N.M. Valiante, J. Chehimi, M. Kubin, M. Aste, S.H. Chan, M. Kobayashi, D. Young, E. Nickbarg, et al. 1992. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J. Exp. Med. 176:1387-1398.
-
(1992)
J. Exp. Med
, vol.176
, pp. 1387-1398
-
-
D'Andrea, A.1
Rengaraju, M.2
Valiante, N.M.3
Chehimi, J.4
Kubin, M.5
Aste, M.6
Chan, S.H.7
Kobayashi, M.8
Young, D.9
Nickbarg, E.10
-
5
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3:133-146.
-
(2003)
Nat. Rev. Immunol
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
6
-
-
33749600724
-
Inborn errors of IL-12/23- and IFN-gamma-mediated immunity: Molecular, cellular, and clinical features
-
Filipe-Santos, O., J. Bustamante, A. Chapgier, G. Vogt, L. de Beaucoudrey, J. Feinberg, E. Jouanguy, S. Boisson-Dupuis, C. Fieschi, C. Picard, and J.L. Casanova. 2006. Inborn errors of IL-12/23- and IFN-gamma-mediated immunity: molecular, cellular, and clinical features. Semin. Immunol. 18:347-361.
-
(2006)
Semin. Immunol
, vol.18
, pp. 347-361
-
-
Filipe-Santos, O.1
Bustamante, J.2
Chapgier, A.3
Vogt, G.4
de Beaucoudrey, L.5
Feinberg, J.6
Jouanguy, E.7
Boisson-Dupuis, S.8
Fieschi, C.9
Picard, C.10
Casanova, J.L.11
-
7
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua, D.J., J. Sherlock, Y. Chen, C.A. Murphy, B. Joyce, B. Seymour, L. Lucian, W. To, S. Kwan, T. Churakova, et al. 2003. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature. 421:744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
-
8
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish, C.L., Y. Chen, W.M. Blumenschein, J. Mattson, B. Basham, J.D. Sedgwick, T. McClanahan, R.A. Kastelein, and D.J. Cua. 2005. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201:233-240.
-
(2005)
J. Exp. Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
9
-
-
0346962972
-
Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
-
Murphy, C.A., C.L. Langrish, Y. Chen, W. Blumenschein, T. McClanahan, R.A. Kastelein, J.D. Sedgwick, and D.J. Cua. 2003. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J. Exp. Med. 198:1951-1957.
-
(2003)
J. Exp. Med
, vol.198
, pp. 1951-1957
-
-
Murphy, C.A.1
Langrish, C.L.2
Chen, Y.3
Blumenschein, W.4
McClanahan, T.5
Kastelein, R.A.6
Sedgwick, J.D.7
Cua, D.J.8
-
10
-
-
33746534417
-
IL-23 promotes tumour incidence and growth
-
Langowski, J.L., X. Zhang, L. Wu, J.D. Mattson, T. Chen, K. Smith, B. Basham, T. McClanahan, R.A. Kastelein, and M. Oft. 2006. IL-23 promotes tumour incidence and growth. Nature. 442:461-465.
-
(2006)
Nature
, vol.442
, pp. 461-465
-
-
Langowski, J.L.1
Zhang, X.2
Wu, L.3
Mattson, J.D.4
Chen, T.5
Smith, K.6
Basham, B.7
McClanahan, T.8
Kastelein, R.A.9
Oft, M.10
-
11
-
-
33750505009
-
Interleukin-23 drives innate and T cell-mediated intestinal inflammation
-
Hue, S., P. Ahern, S. Buonocore, M.C. Kullberg, D.J. Cua, B.S. McKenzie, F. Powrie, and K.J. Maloy. 2006. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J. Exp. Med. 203:2473-2483.
-
(2006)
J. Exp. Med
, vol.203
, pp. 2473-2483
-
-
Hue, S.1
Ahern, P.2
Buonocore, S.3
Kullberg, M.C.4
Cua, D.J.5
McKenzie, B.S.6
Powrie, F.7
Maloy, K.J.8
-
12
-
-
33750530394
-
IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis
-
Kullberg, M.C., D. Jankovic, C.G. Feng, S. Hue, P.L. Gorelick, B.S. McKenzie, D.J. Cua, F. Powrie, A.W. Cheever, K.J. Maloy, and A. Sher. 2006. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. J. Exp. Med. 203:2485-2494.
-
(2006)
J. Exp. Med
, vol.203
, pp. 2485-2494
-
-
Kullberg, M.C.1
Jankovic, D.2
Feng, C.G.3
Hue, S.4
Gorelick, P.L.5
McKenzie, B.S.6
Cua, D.J.7
Powrie, F.8
Cheever, A.W.9
Maloy, K.J.10
Sher, A.11
-
13
-
-
33747089041
-
Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
-
Uhlig, H.H., B.S. McKenzie, S. Hue, C. Thompson, B. Joyce-Shaikh, R. Stepankova, N. Robinson, S. Buonocore, H. Tlaskalova-Hogenova, D.J. Cua, and F. Powrie. 2006. Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity. 25:309-318.
-
(2006)
Immunity
, vol.25
, pp. 309-318
-
-
Uhlig, H.H.1
McKenzie, B.S.2
Hue, S.3
Thompson, C.4
Joyce-Shaikh, B.5
Stepankova, R.6
Robinson, N.7
Buonocore, S.8
Tlaskalova-Hogenova, H.9
Cua, D.J.10
Powrie, F.11
-
14
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen, D., J. Cheung, H. Scheerens, F. Poulet, T. McClanahan, B. McKenzie, M.A. Kleinschek, A. Owyang, J. Mattson, W. Blumenschein, et al. 2006. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J. Clin. Invest. 116:1310-1316.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
Kleinschek, M.A.7
Owyang, A.8
Mattson, J.9
Blumenschein, W.10
-
15
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr, R.H., K.D. Taylor, S.R. Brant, J.D. Rioux, M.S. Silverberg, M.J. Daly, A.H. Steinhart, C. Abraham, M. Regueiro, A. Griffiths, et al. 2006. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 314:1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
-
16
-
-
0035524488
-
Toll-like receptors and innate immunity
-
Medzhitov, R. 2001. Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1:135-145.
-
(2001)
Nat. Rev. Immunol
, vol.1
, pp. 135-145
-
-
Medzhitov, R.1
-
17
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira, S., S. Uematsu, and O. Takeuchi. 2006. Pathogen recognition and innate immunity. Cell. 124:783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
18
-
-
4143131229
-
Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity
-
Whitmore, M.M., M.J. DeVeer, A. Edling, R.K. Oates, B. Simons, D. Lindner, and B.R. Williams. 2004. Synergistic activation of innate immunity by double-stranded RNA and CpG DNA promotes enhanced antitumor activity. Cancer Res. 64:5850-5860.
-
(2004)
Cancer Res
, vol.64
, pp. 5850-5860
-
-
Whitmore, M.M.1
DeVeer, M.J.2
Edling, A.3
Oates, R.K.4
Simons, B.5
Lindner, D.6
Williams, B.R.7
-
19
-
-
33847183077
-
Cooperation of Toll-like receptor signals in innate immune defence
-
Trinchieri, G., and A. Sher. 2007. Cooperation of Toll-like receptor signals in innate immune defence. Nat. Rev. Immunol. 7:179-190.
-
(2007)
Nat. Rev. Immunol
, vol.7
, pp. 179-190
-
-
Trinchieri, G.1
Sher, A.2
-
20
-
-
18644364701
-
A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells
-
Gautier, G., M. Humbert, F. Deauvieau, M. Scuiller, J. Hiscott, E.E. Bates, G. Trinchieri, C. Caux, and P. Garrone. 2005. A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J. Exp. Med. 201:1435-1446.
-
(2005)
J. Exp. Med
, vol.201
, pp. 1435-1446
-
-
Gautier, G.1
Humbert, M.2
Deauvieau, F.3
Scuiller, M.4
Hiscott, J.5
Bates, E.E.6
Trinchieri, G.7
Caux, C.8
Garrone, P.9
-
21
-
-
23944489407
-
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
-
Napolitani, G., A. Rinaldi, F. Bertoni, F. Sallusto, and A. Lanzavecchia. 2005. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat. Immunol. 6:769-776.
-
(2005)
Nat. Immunol
, vol.6
, pp. 769-776
-
-
Napolitani, G.1
Rinaldi, A.2
Bertoni, F.3
Sallusto, F.4
Lanzavecchia, A.5
-
22
-
-
0034194222
-
Biosynthesis and posttranslational regulation of human IL-12
-
Carra, G., F. Gerosa, and G. Trinchieri. 2000. Biosynthesis and posttranslational regulation of human IL-12. J. Immunol. 164:4752-4761.
-
(2000)
J. Immunol
, vol.164
, pp. 4752-4761
-
-
Carra, G.1
Gerosa, F.2
Trinchieri, G.3
-
23
-
-
29144434113
-
TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis
-
Bafica, A., C.A. Scanga, C.G. Feng, C. Leifer, A. Cheever, and A. Sher. 2005. TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. J. Exp. Med. 202:1715-1724.
-
(2005)
J. Exp. Med
, vol.202
, pp. 1715-1724
-
-
Bafica, A.1
Scanga, C.A.2
Feng, C.G.3
Leifer, C.4
Cheever, A.5
Sher, A.6
-
24
-
-
0033618562
-
Host defense mechanisms triggered by microbial lipo-proteins through toll-like receptors
-
Brightbill, H.D., D.H. Libraty, S.R. Krutzik, R.B. Yang, J.T. Belisle, J.R. Bleharski, M. Maitland, M.V. Norgard, S.E. Plevy, S.T. Smale, et al. 1999. Host defense mechanisms triggered by microbial lipo-proteins through toll-like receptors. Science. 285:732-736.
-
(1999)
Science
, vol.285
, pp. 732-736
-
-
Brightbill, H.D.1
Libraty, D.H.2
Krutzik, S.R.3
Yang, R.B.4
Belisle, J.T.5
Bleharski, J.R.6
Maitland, M.7
Norgard, M.V.8
Plevy, S.E.9
Smale, S.T.10
-
25
-
-
77951073629
-
NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis
-
Ferwerda, G., S.E. Girardin, B.J. Kullberg, L. Le Bourhis, D.J. de Jong, D.M. Langenberg, R. van Crevel, G.J. Adema, T.H. Ottenhoff, J.W. Van der Meer, and M.G. Netea. 2005. NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. PLoS Pathog. 1:e34.
-
(2005)
PLoS Pathog
, vol.1
-
-
Ferwerda, G.1
Girardin, S.E.2
Kullberg, B.J.3
Le Bourhis, L.4
de Jong, D.J.5
Langenberg, D.M.6
van Crevel, R.7
Adema, G.J.8
Ottenhoff, T.H.9
Van der Meer, J.W.10
Netea, M.G.11
-
26
-
-
4344575766
-
IL-6 and IL-10 induction from dendritic cells in response to Mycobacterium tuberculosis is predominantly dependent on TLR2-mediated recognition
-
Jang, S., S. Uematsu, S. Akira, and P. Salgame. 2004. IL-6 and IL-10 induction from dendritic cells in response to Mycobacterium tuberculosis is predominantly dependent on TLR2-mediated recognition. J. Immunol. 173:3392-3397.
-
(2004)
J. Immunol
, vol.173
, pp. 3392-3397
-
-
Jang, S.1
Uematsu, S.2
Akira, S.3
Salgame, P.4
-
27
-
-
0033215123
-
Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis
-
Means, T.K., S. Wang, E. Lien, A. Yoshimura, D.T. Golenbock, and M.J. Fenton. 1999. Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis. J. Immunol. 163:3920-3927.
-
(1999)
J. Immunol
, vol.163
, pp. 3920-3927
-
-
Means, T.K.1
Wang, S.2
Lien, E.3
Yoshimura, A.4
Golenbock, D.T.5
Fenton, M.J.6
-
28
-
-
10844264782
-
Analysis of the CARD15 variants R702W, G908R and L1007fs in Italian IBD patients
-
Giachino, D., M.M. van Duist, S. Regazzoni, D. Gregori, M. Bardessono, P. Salacone, N. Scaglione, R. Sostegni, N. Sapone, F. Bresso, et al. 2004. Analysis of the CARD15 variants R702W, G908R and L1007fs in Italian IBD patients. Eur. J. Hum. Genet. 12:206-212.
-
(2004)
Eur. J. Hum. Genet
, vol.12
, pp. 206-212
-
-
Giachino, D.1
van Duist, M.M.2
Regazzoni, S.3
Gregori, D.4
Bardessono, M.5
Salacone, P.6
Scaglione, N.7
Sostegni, R.8
Sapone, N.9
Bresso, F.10
-
29
-
-
0038558249
-
Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2
-
Gantner, B.N., R.M. Simmons, S.J. Canavera, S. Akira, and D.M. Underhill. 2003. Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J. Exp. Med. 197:1107-1117.
-
(2003)
J. Exp. Med
, vol.197
, pp. 1107-1117
-
-
Gantner, B.N.1
Simmons, R.M.2
Canavera, S.J.3
Akira, S.4
Underhill, D.M.5
-
30
-
-
0038558248
-
Dectin-1 mediates the biological effects of β-glucans
-
Brown, G.D., J. Herre, D.L. Williams, J.A. Willment, A.S. Marshall, and S. Gordon. 2003. Dectin-1 mediates the biological effects of β-glucans. J. Exp. Med. 197:1119-1124.
-
(2003)
J. Exp. Med
, vol.197
, pp. 1119-1124
-
-
Brown, G.D.1
Herre, J.2
Williams, D.L.3
Willment, J.A.4
Marshall, A.S.5
Gordon, S.6
-
31
-
-
0037767231
-
Differential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles
-
Qi, H., T.L. Denning, and L. Soong. 2003. Differential induction of interleukin-10 and interleukin-12 in dendritic cells by microbial toll-like receptor activators and skewing of T-cell cytokine profiles. Infect. Immun. 71:3337-3342.
-
(2003)
Infect. Immun
, vol.71
, pp. 3337-3342
-
-
Qi, H.1
Denning, T.L.2
Soong, L.3
-
32
-
-
20244363662
-
-
Rogers, N.C., E.C. Slack, A.D. Edwards, M.A. Nolte, O. Schulz, E. Schweighoffer, D.L. Williams, S. Gordon, V.L. Tybulewicz, G.D. Brown, and C. Reis e Sousa. 2005. Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity. 22:507-517.
-
Rogers, N.C., E.C. Slack, A.D. Edwards, M.A. Nolte, O. Schulz, E. Schweighoffer, D.L. Williams, S. Gordon, V.L. Tybulewicz, G.D. Brown, and C. Reis e Sousa. 2005. Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity. 22:507-517.
-
-
-
-
33
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen, M., R.J. Hocking, C.J. Atkins, R.M. Locksley, and B. Stockinger. 2006. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 24:179-189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
34
-
-
35348948374
-
Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells
-
van Beelen, A.J., Z. Zelinkova, E.W. Taanman-Kueter, F.J. Muller, D.W. Hommes, S.A. Zaat, M.L. Kapsenberg, and E.C. de Jong. 2007. Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells. Immunity. 27:660-669.
-
(2007)
Immunity
, vol.27
, pp. 660-669
-
-
van Beelen, A.J.1
Zelinkova, Z.2
Taanman-Kueter, E.W.3
Muller, F.J.4
Hommes, D.W.5
Zaat, S.A.6
Kapsenberg, M.L.7
de Jong, E.C.8
-
35
-
-
34548125305
-
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
-
Acosta-Rodriguez, E.V., G. Napolitani, A. Lanzavecchia, and F. Sallusto. 2007. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat. Immunol. 8:942-949.
-
(2007)
Nat. Immunol
, vol.8
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
36
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
Wilson, N.J., K. Boniface, J.R. Chan, B.S. McKenzie, W.M. Blumenschein, J.D. Mattson, B. Basham, K. Smith, T. Chen, F. Morel, et al. 2007. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat. Immunol. 8:950-957.
-
(2007)
Nat. Immunol
, vol.8
, pp. 950-957
-
-
Wilson, N.J.1
Boniface, K.2
Chan, J.R.3
McKenzie, B.S.4
Blumenschein, W.M.5
Mattson, J.D.6
Basham, B.7
Smith, K.8
Chen, T.9
Morel, F.10
-
37
-
-
0029040855
-
Regulation of interleukin-12 expression in human monocytes: Selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes
-
Hayes, M.P., J. Wang, and M.A. Norcross. 1995. Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes. Blood. 86:646-650.
-
(1995)
Blood
, vol.86
, pp. 646-650
-
-
Hayes, M.P.1
Wang, J.2
Norcross, M.A.3
-
38
-
-
0028911482
-
Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: Priming for IL-12 and tumor necrosis factor α production
-
D'Andrea, A., X. Ma, M. Aste-Amezaga, C. Paganin, and G. Trinchieri. 1995. Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor α production. J. Exp. Med. 181:537-546.
-
(1995)
J. Exp. Med
, vol.181
, pp. 537-546
-
-
D'Andrea, A.1
Ma, X.2
Aste-Amezaga, M.3
Paganin, C.4
Trinchieri, G.5
-
39
-
-
0030064148
-
The interleukin 12 p40 gene promoter is primed by interferon γ in monocytic cells
-
Ma, X., J.M. Chow, G. Gri, G. Carra, F. Gerosa, S.F. Wolf, R. Dzialo, and G. Trinchieri. 1996. The interleukin 12 p40 gene promoter is primed by interferon γ in monocytic cells. J. Exp. Med. 183:147-157.
-
(1996)
J. Exp. Med
, vol.183
, pp. 147-157
-
-
Ma, X.1
Chow, J.M.2
Gri, G.3
Carra, G.4
Gerosa, F.5
Wolf, S.F.6
Dzialo, R.7
Trinchieri, G.8
-
40
-
-
0033697454
-
-
Schulz, O., D.A. Edwards, M. Schito, J. Aliberti, S. Manickasingham, A. Sher, and C. Reis e Sousa. 2000. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity. 13:453-462.
-
Schulz, O., D.A. Edwards, M. Schito, J. Aliberti, S. Manickasingham, A. Sher, and C. Reis e Sousa. 2000. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity. 13:453-462.
-
-
-
-
41
-
-
0034650811
-
Disparate intracellular processing of human IL-12 preprotein subunits: Atypical processing of the P35 signal peptide
-
Murphy, F.J., M.P. Hayes, and P.R. Burd. 2000. Disparate intracellular processing of human IL-12 preprotein subunits: atypical processing of the P35 signal peptide. J. Immunol. 164:839-847.
-
(2000)
J. Immunol
, vol.164
, pp. 839-847
-
-
Murphy, F.J.1
Hayes, M.P.2
Burd, P.R.3
-
42
-
-
34248655973
-
Correlates of immune protection from tuberculosis
-
Fletcher, H.A. 2007. Correlates of immune protection from tuberculosis. Curr. Mol. Med. 7:319-325.
-
(2007)
Curr. Mol. Med
, vol.7
, pp. 319-325
-
-
Fletcher, H.A.1
-
43
-
-
34248562792
-
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
-
Khader, S.A., G.K. Bell, J.E. Pearl, J.J. Fountain, J. Rangel-Moreno, G.E. Cilley, F. Shen, S.M. Eaton, S.L. Gaffen, S.L. Swain, et al. 2007. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat. Immunol. 8:369-377.
-
(2007)
Nat. Immunol
, vol.8
, pp. 369-377
-
-
Khader, S.A.1
Bell, G.K.2
Pearl, J.E.3
Fountain, J.J.4
Rangel-Moreno, J.5
Cilley, G.E.6
Shen, F.7
Eaton, S.M.8
Gaffen, S.L.9
Swain, S.L.10
-
44
-
-
33947195292
-
IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis Bacille Calmette-Guerin infection
-
Umemura, M., A. Yahagi, S. Hamada, M.D. Begum, H. Watanabe, K. Kawakami, T. Suda, K. Sudo, S. Nakae, Y. Iwakura, and G. Matsuzaki. 2007. IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis Bacille Calmette-Guerin infection. J. Immunol. 178:3786-3796.
-
(2007)
J. Immunol
, vol.178
, pp. 3786-3796
-
-
Umemura, M.1
Yahagi, A.2
Hamada, S.3
Begum, M.D.4
Watanabe, H.5
Kawakami, K.6
Suda, T.7
Sudo, K.8
Nakae, S.9
Iwakura, Y.10
Matsuzaki, G.11
-
45
-
-
33845441578
-
Interleukin-23 restores immunity to Mycobacterium tuberculosis infection in IL-12p40-deficient mice and is not required for the development of IL-17-secreting T cell responses
-
Wozniak, T.M., A.A. Ryan, and W.J. Britton. 2006. Interleukin-23 restores immunity to Mycobacterium tuberculosis infection in IL-12p40-deficient mice and is not required for the development of IL-17-secreting T cell responses. J. Immunol. 177:8684-8692.
-
(2006)
J. Immunol
, vol.177
, pp. 8684-8692
-
-
Wozniak, T.M.1
Ryan, A.A.2
Britton, W.J.3
-
46
-
-
23244458100
-
IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available
-
Khader, S.A., J.E. Pearl, K. Sakamoto, L. Gilmartin, G.K. Bell, D.M. Jelley-Gibbs, N. Ghilardi, F. deSauvage, and A.M. Cooper. 2005. IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available. J. Immunol. 175:788-795.
-
(2005)
J. Immunol
, vol.175
, pp. 788-795
-
-
Khader, S.A.1
Pearl, J.E.2
Sakamoto, K.3
Gilmartin, L.4
Bell, G.K.5
Jelley-Gibbs, D.M.6
Ghilardi, N.7
deSauvage, F.8
Cooper, A.M.9
-
47
-
-
0035903288
-
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
-
Kadowaki, N., S. Ho, S. Antonenko, R.W. Malefyt, R.A. Kastelein, F. Bazan, and Y.J. Liu. 2001. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J. Exp. Med. 194:863-869.
-
(2001)
J. Exp. Med
, vol.194
, pp. 863-869
-
-
Kadowaki, N.1
Ho, S.2
Antonenko, S.3
Malefyt, R.W.4
Kastelein, R.A.5
Bazan, F.6
Liu, Y.J.7
-
48
-
-
34249026701
-
-
LeibundGut-Landmann, S., O. Gross, M.J. Robinson, F. Osorio, E.C. Slack, S.V. Tsoni, E. Schweighoffer, V. Tybulewicz, G.D. Brown, J. Ruland, and C. Reis e Sousa. 2007. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat. Immunol. 8:630-638.
-
LeibundGut-Landmann, S., O. Gross, M.J. Robinson, F. Osorio, E.C. Slack, S.V. Tsoni, E. Schweighoffer, V. Tybulewicz, G.D. Brown, J. Ruland, and C. Reis e Sousa. 2007. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat. Immunol. 8:630-638.
-
-
-
-
49
-
-
0027240219
-
Interleukin-10 inhibits human lymphocyte IFN-γ production by suppressing natural killer cell stimulatory factor/interleukin-12 synthesis in accessory cells
-
D'Andrea, A., M. Aste-Amezaga, N.M. Valiante, X. Ma, M. Kubin, and G. Trinchieri. 1993. Interleukin-10 inhibits human lymphocyte IFN-γ production by suppressing natural killer cell stimulatory factor/interleukin-12 synthesis in accessory cells. J. Exp. Med. 178:1041-1048.
-
(1993)
J. Exp. Med
, vol.178
, pp. 1041-1048
-
-
D'Andrea, A.1
Aste-Amezaga, M.2
Valiante, N.M.3
Ma, X.4
Kubin, M.5
Trinchieri, G.6
-
50
-
-
10344243503
-
IL-10 released by concomitant TLR2 stimulation blocks the induction of a subset of Th1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells
-
Re, F., and J.L. Strominger. 2004. IL-10 released by concomitant TLR2 stimulation blocks the induction of a subset of Th1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells. J. Immunol. 173:7548-7555.
-
(2004)
J. Immunol
, vol.173
, pp. 7548-7555
-
-
Re, F.1
Strominger, J.L.2
-
51
-
-
1542409922
-
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells
-
Netea, M.G., R. Sutmuller, C. Hermann, C.A. Van der Graaf, J.W. Van der Meer, J.H. van Krieken, T. Hartung, G. Adema, and B.J. Kullberg. 2004. Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells. J. Immunol. 172:3712-3718.
-
(2004)
J. Immunol
, vol.172
, pp. 3712-3718
-
-
Netea, M.G.1
Sutmuller, R.2
Hermann, C.3
Van der Graaf, C.A.4
Van der Meer, J.W.5
van Krieken, J.H.6
Hartung, T.7
Adema, G.8
Kullberg, B.J.9
-
52
-
-
1842477227
-
A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells
-
Dillon, S., A. Agrawal, T. Van Dyke, G. Landreth, L. McCauley, A. Koh, C. Maliszewski, S. Akira, and B. Pulendran. 2004. A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells. J. Immunol. 172:4733-4743.
-
(2004)
J. Immunol
, vol.172
, pp. 4733-4743
-
-
Dillon, S.1
Agrawal, A.2
Van Dyke, T.3
Landreth, G.4
McCauley, L.5
Koh, A.6
Maliszewski, C.7
Akira, S.8
Pulendran, B.9
-
53
-
-
32444432610
-
Toll-like receptor 2 controls expansion and function of regulatory T cells
-
Sutmuller, R.P., M.H. den Brok, M. Kramer, E.J. Bennink, L.W. Toonen, B.J. Kullberg, L.A. Joosten, S. Akira, M.G. Netea, and G.J. Adema. 2006. Toll-like receptor 2 controls expansion and function of regulatory T cells. J. Clin. Invest. 116:485-494.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 485-494
-
-
Sutmuller, R.P.1
den Brok, M.H.2
Kramer, M.3
Bennink, E.J.4
Toonen, L.W.5
Kullberg, B.J.6
Joosten, L.A.7
Akira, S.8
Netea, M.G.9
Adema, G.J.10
-
54
-
-
0142156744
-
Differential regulation of interleukin (IL)-12 p35 and p40 gene expression and interferon (IFN)-γ-primed IL-12 production by IFN regulatory factor 1
-
Liu, J., S. Cao, L.M. Herman, and X. Ma. 2003. Differential regulation of interleukin (IL)-12 p35 and p40 gene expression and interferon (IFN)-γ-primed IL-12 production by IFN regulatory factor 1. J. Exp. Med. 198:1265-1276.
-
(2003)
J. Exp. Med
, vol.198
, pp. 1265-1276
-
-
Liu, J.1
Cao, S.2
Herman, L.M.3
Ma, X.4
-
55
-
-
0029112744
-
Inhibition of IL-10 expression by IFN-gamma upregulates transcription of TNF-alpha in human monocytes
-
Donnelly, R.P., S.L. Freeman, and M.P. Hayes. 1995. Inhibition of IL-10 expression by IFN-gamma upregulates transcription of TNF-alpha in human monocytes. J. Immunol. 155:1420-1427.
-
(1995)
J. Immunol
, vol.155
, pp. 1420-1427
-
-
Donnelly, R.P.1
Freeman, S.L.2
Hayes, M.P.3
-
56
-
-
33845930737
-
IFN-gamma negatively regulates CpG-induced IL-10 in bone marrow-derived dendritic cells
-
Flores, R.R., K.A. Diggs, L.M. Tait, and P.A. Morel. 2007. IFN-gamma negatively regulates CpG-induced IL-10 in bone marrow-derived dendritic cells. J. Immunol. 178:211-218.
-
(2007)
J. Immunol
, vol.178
, pp. 211-218
-
-
Flores, R.R.1
Diggs, K.A.2
Tait, L.M.3
Morel, P.A.4
-
57
-
-
33646595287
-
IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins
-
Hu, X., P.K. Paik, J. Chen, A. Yarilina, L. Kockeritz, T.T. Lu, J.R. Woodgett, and L.B. Ivashkiv. 2006. IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins. Immunity. 24:563-574.
-
(2006)
Immunity
, vol.24
, pp. 563-574
-
-
Hu, X.1
Paik, P.K.2
Chen, J.3
Yarilina, A.4
Kockeritz, L.5
Lu, T.T.6
Woodgett, J.R.7
Ivashkiv, L.B.8
-
58
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
Acosta-Rodriguez, E.V., L. Rivino, J. Geginat, D. Jarrossay, M. Gattorno, A. Lanzavecchia, F. Sallusto, and G. Napolitani. 2007. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat. Immunol. 8:639-646.
-
(2007)
Nat. Immunol
, vol.8
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
Rivino, L.2
Geginat, J.3
Jarrossay, D.4
Gattorno, M.5
Lanzavecchia, A.6
Sallusto, F.7
Napolitani, G.8
-
59
-
-
0034658107
-
Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans: Implications for initiation of T helper cell immunity in vitro and in vivo
-
d'Ostiani, C.F., G. Del Sero, A. Bacci, C. Montagnoli, A. Spreca, A. Mencacci, P. Ricciardi-Castagnoli, and L. Romani. 2000. Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans: implications for initiation of T helper cell immunity in vitro and in vivo. J. Exp. Med. 191:1661-1674.
-
(2000)
J. Exp. Med
, vol.191
, pp. 1661-1674
-
-
d'Ostiani, C.F.1
Del Sero, G.2
Bacci, A.3
Montagnoli, C.4
Spreca, A.5
Mencacci, A.6
Ricciardi-Castagnoli, P.7
Romani, L.8
-
60
-
-
0842347722
-
The interaction of human dendritic cells with yeast and germ-tube forms of Candida albicans leads to efficient fungal processing, dendritic cell maturation, and acquisition of a Th1 response-promoting function
-
Romagnoli, G., R. Nisini, P. Chiani, S. Mariotti, R. Teloni, A. Cassone, and A. Torosantucci. 2004. The interaction of human dendritic cells with yeast and germ-tube forms of Candida albicans leads to efficient fungal processing, dendritic cell maturation, and acquisition of a Th1 response-promoting function. J. Leukoc. Biol. 75:117-126.
-
(2004)
J. Leukoc. Biol
, vol.75
, pp. 117-126
-
-
Romagnoli, G.1
Nisini, R.2
Chiani, P.3
Mariotti, S.4
Teloni, R.5
Cassone, A.6
Torosantucci, A.7
-
61
-
-
17144370549
-
Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments
-
Gantner, B.N., R.M. Simmons, and D.M. Underhill. 2005. Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments. EMBO J. 24:1277-1286.
-
(2005)
EMBO J
, vol.24
, pp. 1277-1286
-
-
Gantner, B.N.1
Simmons, R.M.2
Underhill, D.M.3
-
62
-
-
3242814586
-
Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice
-
Huang, W., L. Na, P.L. Fidel, and P. Schwarzenberger. 2004. Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J. Infect. Dis. 190:624-631.
-
(2004)
J. Infect. Dis
, vol.190
, pp. 624-631
-
-
Huang, W.1
Na, L.2
Fidel, P.L.3
Schwarzenberger, P.4
-
63
-
-
30744434833
-
IL-23 enhances the inflammatory cell response in Cryptococcus neoformans infection and induces a cytokine pattern distinct from IL-12
-
Kleinschek, M.A., U. Muller, S.J. Brodie, W. Stenzel, G. Kohler, W.M. Blumenschein, R.K. Straubinger, T. McClanahan, R.A. Kastelein, and G. Alber. 2006. IL-23 enhances the inflammatory cell response in Cryptococcus neoformans infection and induces a cytokine pattern distinct from IL-12. J. Immunol. 176:1098-1106.
-
(2006)
J. Immunol
, vol.176
, pp. 1098-1106
-
-
Kleinschek, M.A.1
Muller, U.2
Brodie, S.J.3
Stenzel, W.4
Kohler, G.5
Blumenschein, W.M.6
Straubinger, R.K.7
McClanahan, T.8
Kastelein, R.A.9
Alber, G.10
-
64
-
-
33846963844
-
Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans
-
Saijo, S., N. Fujikado, T. Furuta, S.H. Chung, H. Kotaki, K. Seki, K. Sudo, S. Akira, Y. Adachi, N. Ohno, et al. 2007. Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans. Nat. Immunol. 8:39-46.
-
(2007)
Nat. Immunol
, vol.8
, pp. 39-46
-
-
Saijo, S.1
Fujikado, N.2
Furuta, T.3
Chung, S.H.4
Kotaki, H.5
Seki, K.6
Sudo, K.7
Akira, S.8
Adachi, Y.9
Ohno, N.10
-
65
-
-
33846962860
-
Dectin-1 is required for beta-glucan recognition and control of fungal infection
-
Taylor, P.R., S.V. Tsoni, J.A. Willment, K.M. Dennehy, M. Rosas, H. Findon, K. Haynes, C. Steele, M. Botto, S. Gordon, and G.D. Brown. 2007. Dectin-1 is required for beta-glucan recognition and control of fungal infection. Nat. Immunol. 8:31-38.
-
(2007)
Nat. Immunol
, vol.8
, pp. 31-38
-
-
Taylor, P.R.1
Tsoni, S.V.2
Willment, J.A.3
Dennehy, K.M.4
Rosas, M.5
Findon, H.6
Haynes, K.7
Steele, C.8
Botto, M.9
Gordon, S.10
Brown, G.D.11
-
66
-
-
0021005310
-
Immunoprecipitation of proteins from cell-free translations
-
Anderson, D.J., and G. Blobel. 1983. Immunoprecipitation of proteins from cell-free translations. Methods Enzymol. 96:111-120.
-
(1983)
Methods Enzymol
, vol.96
, pp. 111-120
-
-
Anderson, D.J.1
Blobel, G.2
-
67
-
-
0000923841
-
Polyacrylamide gel electrophoresis of viral protein
-
K. Maramarosch and H. Koprowski, editors. Academic Press, New York
-
Maizel, J.V. 1971. Polyacrylamide gel electrophoresis of viral protein. In Methods in Virology. Vol. 5. K. Maramarosch and H. Koprowski, editors. Academic Press, New York. 179-191.
-
(1971)
Methods in Virology
, vol.5
, pp. 179-191
-
-
Maizel, J.V.1
-
68
-
-
0016697588
-
A genetic marker in the variable region of rabbit immunoglobulin heavy chain
-
Mole, L.R. 1975. A genetic marker in the variable region of rabbit immunoglobulin heavy chain. Biochem. J. 151:351-359.
-
(1975)
Biochem. J
, vol.151
, pp. 351-359
-
-
Mole, L.R.1
|