IFN-γ Suppresses IL-10 Production and Synergizes with TLR2 by Regulating GSK3 and CREB/AP-1 Proteins

Immunity

Volumn 24, Issue 5, 2006, Pages 563-574

  Hu, Xiaoyu ^a   Paik, Paul K ^b   Chen, Janice ^c   Yarilina, Anna ^a   Kockeritz, Lisa ^d   Lu, Theresa T ^c   Woodgett, James R ^d   Ivashkiv, Lionel B ^a,b,c  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c Weill Cornell Graduate School of Biomedical Sciences   (United States)

^d PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

MOLIMMUNO

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GAMMA INTERFERON; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 10; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; STAT3 PROTEIN; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; ZYMOSAN;

ANTIGEN ANTIBODY COMPLEX; ARTHRITIS; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; PERITONITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION;

ANIMALS; ARTHRITIS; CREB-BINDING PROTEIN; DISEASE MODELS, ANIMAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; MICE; MODELS, IMMUNOLOGICAL; PERITONITIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TOLL-LIKE RECEPTOR 2; TRANSCRIPTION FACTOR AP-1; TRANSFECTION;

EID: 33646595287     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2006.02.014     Document Type: Article

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