Helicobacter Infections in Mice

The Mouse in Biomedical Research

Volumn 2, Issue , 2007, Pages 407-435

  Fox, James G ^a   Whary, Mark T ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 44649124404     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012369454-6/50045-5     Document Type: Chapter

References (193)

1. Andrutis K.A., Fox J.G., Schauer D.B., Marini R.P., Murphy J.C., Yan L., et al. Inability of an isogenic urease-negative mutant stain of Helicobacter mustelae to colonize the ferret stomach. Infect. Immun. 1995, 63:3722-3725.
2. Assreuy J., Cunha F.Q., Epperlein M., Noronha-Dutra A., O'Donnell C.A., Liew F.Y., et al. Production of nitric oxide and Superoxide by activated macrophages and killing ofLeishmania major. Eur. J. Immunol. 1994, 24:672-676.
3. Bannasch P. (Personal communication).
4. Bannasch P., Benner U., Enzmann H., Hacker H.J. Tigroid cell foci and neoplastic nodules in the liver of rats treated with a single dose of aflatoxin Bl. Carcinogenesis 1985, 6:1641-1648.
5. Beckwith C.S., Franklin C.L., Hook R.R., Besch-Williford C.L., Riley L.K. Fecal PCR assay for diagnosis of Helicobacter infection in laboratory rodents. J. Clin. Microbiol. 1997, 35:1620-1623.
6. Beckwith C.S., McGee D.J., Mobley H.L., Riley L.K. Cloning expression and catalytic activity of Helicobacter hepaticus urease. Infect. Immun. 2001, 69:5914-5920.
7. Berg D.J., Davidson N, Kuhn R., Muller W., Menon S., Holland G., et al. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4 (+) THl-like responses. J. Clin. Invest. 1996, 98:1010-1020.
8. Blaser M.J., Atherton J.C. Helicobacter pylori persistence: biology and disease. J. Clin. Invest. 2004, 113:321-333.
9. Boutin S., Rogers A., Shen Z., Love J., Fry R., Nambiar P., et al. Hepatic temporal gene expression profiling in Helicobacter hepaticus infected A/JCr mice. Toxicol Pathol. 2004, 32:678-693.
10. Bucher J.R., Hailey J.R., Roycroft J.R., Haseman J.K., Sills R.C., Grumbein S.L., et al. Inhalation toxicity and carcinogenicity studies of cobalt sulfate. Toxicol. Sci. 1999, 49:56-67.
11. Burich A., Hershberg R., Waggie K., Zeng W., Brabb T., Westlich G., et al. Helicobacter-induced inflammatory bowel disease in IL-10-and T cell-deficient mice. Am. J. Physiol Gastrointest. Liver Physiol 2001, 281:G764-G778.
12. Burney S., Niles J.C., Dedon P.C., Tannenbaum S.R. DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite. Chem. Res. Toxicol. 1999, 12:513-520.
13. Cadet J., Douki T., Ravanat J.L. Artifacts associated with the measurement of oxidized DNA bases. Environ. Health Perspect. 1997, 105:1034-1039.
14. Cahill R.J., Foltz C.J., Fox J.G., Dangler C.A., Powrie F., Schauer D.B. Inflammatory bowel disease: an immunity-mediated condition trig-gered by bacterial infection with. Helicobacter hepaticus. Infect. Immun. 1997, 65:3126-3131.
15. Cahill R.J., Kilgallen C., Beattie S., Hamilton H., O'Morain C. Gastric epithelial cell kinetics in the progression from normal mucosa to gas-tric carcinoma. Gut 1996, 38:177-181.
16. Canella K.A., Diwan B.A., Gorelick P.L., Donovan P.J., Sipowicz M.A., Kasprzak K.S., et al. Liver tumorigenesis by Helicobacter hepati-cus: considerations of mechanism. In Vivo 1996, 10:285-292.
17. Chin E.Y, Dangler C.A., Fox J.G., Schauer D.B. Helicobacter hepaticus infection triggers inflammatory bowel disease in T cell receptor alphabeta mutant mice. Comp. Med. 2000, 50:586-594.
18. Clyne M., Labigne A., Drumm B. Helicobacter pylori requires an acidic environment to survive in the presence of urea. Infect. Immun. 1995, 63:1669-1673.
19. Coletta P.L., Muller A.M., Jones E.A., Muhl B., Holwell S., Clarke D., et al. Lymphodepletion in the ApcMin/+ mouse model of intestinal tumorigenesis. Blood 2004, 103:1050-1058.
20. Compton S.R., Ball-Goodrich L.J., Zeiss C.J., Johnson L.K., Johnson E.A., Macy J.D. Pathogenesis of mouse hepatitis virus infection in gamma interferon-deficient mice is modulated by co-infection with. Helicobacter hepaticus. Comp. Med. 2003, 53:197-206.
21. Correa P. Bacterial infections as a cause of cancer. J. Natl. Cancer Inst. 2003, 95:E3.
22. Corthesy-Theulaz L, Porta N., Glauser M., Saraga E., Vaney A.C., Haas R., et al. Oral immunization with Helicobacter pylori urease B subunit as a treatment against Helicobacter infection in mice. Gastroenterology 1995, 109:115-121.
23. Crabtree J.E., Ferrero R.L., Kusters J.G. The mouse colonizing Helicobacter pylori strain SSI may lack a functional cag pathogenicity island. Helicobacter 2002, 7:139-140].
24. Crabtree J.E., Ferrero R.L., Kusters J.G. The mouse colonizing Helicobacter pylori strain SSI may lack a functional cag pathogenicity island. Helicobacter 2002, 7:131-140. author reply.
25. Crabtree J.E., Shallcross T.M., Heatley R.V., Wyatt J.I. Mucosal tumour necrosis factor alpha and interleukin-6 in patients with Helicobacter pylori associated gastritis. Gut 1991, 32:1473-1477.
26. Danon S.J., Luria B.J., Mankoski R.E., Eaton K.A. RFLP and RAPD analysis of in vivo genetic interactions between strains of. Helicobacter pylori. Helicobacter 1998, 3:254-259.
27. Davies G.R., Banatvala N., Collins C.E., Sheaff M.T., Abdi Y, Clements L., et al. Relationship between infective load of Helicobacter pylori and reactive oxygen metabolite production in antral mucosa. Scand. J. Gastroenterol. 1994, 29:419-424.
28. Dedon P.C., Plastaras J.P., Rouzer C.A., Marnett L.J. Indirect mutagenesis by oxidative DNA damage: formation of the pyrimidopurinone adduct of deoxyguanosine by base propenal. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:11113-11116.
29. Dewhirst F.E., Fox J.G., Mendes E.N., Paster B.J., Gates C.E., Kirkbride C.A., et al. 'Flexispira rappini' strains represent at least 10 Helicobacter taxa. Int. J. Syst. Evol Microbiol. 2000, 50 Pt 5:1781-1787.
30. Dewhirst F.E., Fox J.G., On S.L. Recommended minimal stan-dards for describing new species of the genus. Helicobacter. Int. J. Syst. Evol. Microbiol. 2000, 50:2231-2237. Pt 6.
31. Dial E.J., Hall L.R., Romero J.J., Lechago J., Fox J.G., Lichtenberger L.M. Altered gastrin regulation in mice infected with. Helicobacter felis. Dig. Dis. Sci. 2000, 45:1308-1314.
32. Dieleman L.A., Arends A., Tonkonogy S.L., Goerres M.S., Craft D.W., Grenther W., et al. Helicobacter hepaticus does not induce or poten-tiate colitis in interleukin-10-deficient mice. Infect. Immun. 2000, 68:5107-5113.
33. Dindzans V.J., Skamene E., Levy G.A. Susceptibility/resistance to mouse hepatitis virus strain 3 and macrophage procoagulant activity are genetically linked and controlled by two non-H-2-linked genes. J. Immunol. 1986, 137:2355-2360.
34. Diwan B.A., Ward J.M., Ramljak D., Anderson L.M. Promotion by Helicobacter hepaticus-induced hepatitis of hepatic tumors initiated by N-nitrosodimethylamine in male A/JCr mice. Toxicol Pathol. 1997, 25:597-605.
35. Drazenovich N.L., Franklin C.L., Livingston R.S., Besselsen D.G. Detection of rodent Helicobacter spp. by use of fluorogenic nucle-ase polymerase chain reaction assays. Comp. Med. 2002, 52:347-353.
36. Drinkwater N.R. Genetic control of hepatocarcinogenesis in C3H mice. Drug Metab. Rev. 1994, 26:201-208.
37. Drinkwater N.R., Ginsler J.J. Genetic control of hepatocarcinogen-esis in C57BL/6J and C3H/HeJ inbred mice. Carcinogenesis 1986, 7:1701-1707.
38. Eaton K.A., Gilbert J.V., Joyce E.A., Wanken A.E., Thevenot T., Baker P., et al. In vivo complementation of ureB restores the ability of Helicobacter pylori to colonize. Infect. Immun. 2002, 70:771-778.
39. El-Omar E.M., Carrington M., Chow W.H., McColl K.E., Bream J.H., Young H.A., et al. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 2000, 404:398-402.
40. El-Omar E.M., Carrington M., Chow W.H., McColl K.E., Bream J.H., Young H.A., et al. The role of interleukin-1 polymorphisms in the pathogenesis of gastric cancer. Nature 2001, 412:99.
41. Enno A., O'Rourke J.L., Howlett C.R., Jack A., Dixon M.F., Lee A. MALToma-like lesions in the murine gastric mucosa after long-term infection with Helicobacter felis. A mouse model of Helicobacter pylori-induced gastric lymphoma. Am. J. Pathol. 1995, 147:217-222.
42. Erdman S., Fox J.G., Dangler C.A., Feldman D., Horwitz B.H. Typhlocolitis in NF-kappa B-deficient mice. J. Immunol. 2001, 166:1443-1447.
43. Erdman S.E., Poutahidis T., Tomczak M., Rogers A.B., Cormier K., Plank B., et al. CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice. Am. J. Pathol. 2003, 162:691-702.
44. Erdman S.E., Rao V.P., Poutahidis T., Ihrig M.M., Ge Z., Feng Y, et al. CD4 (+) CD25 (+) regulatory lymphocytes require interleukin 10 to interrupt colon carcinogenesis in mice. Cancer Res. 2003, 63:6042-6050.
45. Fan X., Gunasena H., Gonzales M., Alamanza Z., Cheng G., Ye C., et al. Helicobacter pylori urease binds to class II MHC molecules on gastric epithelial cells to initiate apoptosis. Gastroenterology 1998, 114:G0485.
46. Feng S., Hodzic E., Kendall L.V., Smith A., Freet K., Barthold S.W. Cloning and expression of a Helicobacter bilis immunoreactive protein. Clin. Diagn. Lab. Immunol. 2002, 9:627-632.
47. Flavell D.J., Lucas S.B. Promotion of N-nitrosodimethylamine-initiated bile duct carcinogenesis in the hamster by the human liver fluke. Opisthorchis viverrini. Carcinogenesis 1983, 4:927-930.
48. Floyd R.A. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis 1990, 11:1447-1450.
49. Foltz C.J., Fox J.G., Cahill R., Murphy J.C., Yan L., Shames B., et al. Spontaneous inflammatory bowel disease in multiple mutant mouse lines: association with colonization by. Helicobacter hepaticus. Helicobacter 1998, 3:69-78.
50. Foltz C.J., Fox J.G., Yan L., Shames B. Evaluation of antibiotic therapies for eradication of. Helicobacter hepaticus. Antimicrob. Agents Chemother. 1995, 39:1292-1294.
51. Foltz C.J., Fox J.G., Yan L., Shames B. Evaluation of various oral antimicrobial formulations for eradication of Helicobacter hepaticus. Lab. Anim. Sci. 1996, 46:193-197.
52. Fox J.G. The non-H pylori helicobacters: their expanding role in gastrointestinal and systemic diseases. Gut 2002, 50:273-283.
53. Fox J.G., Beck P., Dangler C.A., Whary M.T., Wang T.C., Shi H.N., et al. Concurrent enteric helminth infection modulates inflamma-tion and gastric immune responses and reduces helicobacter-induced gastric atrophy. Nat. Med. 2000, 6:536-542.
54. Fox J.G., Dangler C.A., Schauer D.B. Inflammatory Bowel Disease in Mouse Models: Role of Gastrointestinal Microbiota As Proinflammatory Modulators. Pathology of genetically engineered mice 2000, 299-315. Iowa State University Press, Ames Iowa. J. Ward, J. Mahler, R. Maronpot, J. Sundberg, R. Frederickson (Eds.).
55. Fox J.G., Dangler C.A., Taylor N.S., King A., Koh T.J., Wang T.C. High-salt diet induces gastric epithelial hyperplasia and parietal cell loss and enhances Helicobacter pylori colonization in C57BL/6 mice. Cancer Res. 1999, 59:4823-4828.
56. Fox J.G., Dangler C.A., Whary M.T., Edelman W, Kucherlapati R., Wang T.C. Mice carrying a truncated Ape gene have diminished gastric epithelial proliferation gastric inflammation and humoral immunity in response to Helicobacter felis infection. Cancer Res. 1997, 57:3972-3978.
57. Fox J.G., Dewhirst F.E., Shen Z., Feng Y, Taylor N.S., Paster B.J., et al. Hepatic Helicobacter species identified in bile and gallbladder tissue from Chileans with chronic cholecystitis. Gastroenterology 1998, 114:755-763.
58. Fox J.G., Dewhirst F.E., Tully J.G., Paster B.J., Yan L., Taylor N.S., et al. Helicobacter hepaticus sp. nov. a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice. J. Clin. Microbiol. 1994, 32:1238-1245.
59. Ward J.M. A novel urease-negative Helicobacter species associ-ated with colitis and typhlitis in IL-10-deficient mice. Infect. Immun. 1999, 67:1757-1762.
60. Fox J.G., Lee A. The role of Helicobacter species in newly recog-nized gastrointestinal tract diseases of animals. Lab. Anim. Sci. 1997, 47:222-255.
61. Fox J.G., Lee A., Otto G., Taylor N.S., Murphy J.C. Helicobacter felis gastritis in gnotobiotic rats: an animal model of Helicobacter pylori gastritis. Infect. Immun. 1991, 59:785-791.
62. Fox J.G., Li X., Yan L., Cahill R.J., Hurley R., Lewis R., et al. Chronic proliferative hepatitis in A/JCr mice associated with persistent H. hepaticus infection: A model of Helicobacter induced carcinogenesis (abstract). Gastroenterology 1996, 110:Al191.
63. Fox J.G., Li X., Yan L., Cahill R.J., Hurley R., Lewis R., et al. Chronic proliferative hepatitis in A/JCr mice associated with persistent Helicobacter hepaticus infection: a model of helicobacter-induced carcino-genesis. Infect. Immun. 1996, 64:1548-1558.
64. Fox J.G., MacGregor J.A., Shen Z., Li X., Lewis R., Dangler C.A. Comparison of methods of identifying Helicobacter hepaticus in B6C3F1 mice used in a carcinogenesis bioassay. J. Clin. Microbiol. 1998, 36:1382-1387.
65. Fox J.G., Rogers A.B., Ihrig M., Taylor N.S., Whary M.T., Dockray G., et al. Helicobacter pylori-associated gastric cancer in INS-GAS mice is gender specific. Cancer Res. 2003, 63:942-950.
66. Fox J.G., Rogers A.B., Whary M.T., Taylor N.S., Xu S., Feng Y, et al. Helicobacter bills associated hepatitis in outbred mice. Comp. Med. 2004, 54:571-577.
67. Fox J.G., Shen Z., Xu S., Feng Y, Dangler C.A., Dewhirst F.E., et al. Helicobacter marmotae sp. nov. isolated from livers of woodchucks and intestines of cats. J. Clin. Microbiol. 2002, 40:2513-2519.
68. Fox J.G., Sheppard B.J., Dangler C.A., Whary M.T., Ihrig M., Wang T.C. Germ-line p53-targeted disruption inhibits helicobac-ter-induced premalignant lesions and invasive gastric carcinoma through down-regulation of Thl proinflammatory responses. Cancer Res. 2002, 62:696-702.
69. Fox J.G., Wang T.C., Rogers A.B., Poutahidis T., Ge Z., Taylor N., et al. Host and microbial constituents influence Helicobacter pylori-induced cancer in a murine model of hypergastrinemia. Gastroenterology 2003, 124:1879-1890.
70. Fox J.G., Wishnok J.S., Murphy J.C., Tannenbaum S.R., Correa P. MNNG-induced gastric carcinoma in ferrets infected with. Helicobacter mustelae. Carcinogenesis 1993, 14:1957-1961.
71. Fox J.G., Yan L.L., Dewhirst F.E., Paster B.J., Shames B., Murphy J.C., et al. Helicobacter bilis sp. nov. a novel Helicobacter species iso-lated from bile livers and intestines of aged inbred mice. J. Clin. Microbiol. 1995, 33:445-454.
72. Fox J.G., Yan L., Shames B., Campbell J., Murphy J.C., Li X. Persistent hepatitis and enterocolitis in germfree mice infected with. Helicobacter hepaticus. Infect. Immun. 1996, 64:3673-3681.
73. Franklin C.L., Beckwith C.S., Livingston R.S., Riley L.K., Gibson S.V., Besch-Williford C.L., et al. Isolation of a novel Helicobacter species Helicobacter cholecystus sp. nov. from the gallbladders of Syrian ham-sters with cholangiofibrosis and centrilobular pancreatitis. J. Clin. Microbiol. 1996, 34:2952-2958.
74. Franklin C.L., Gorelick P.L., Riley L.K., Dewhirst F.E., Livingston R.S., Ward J.M., et al. Helicobacter typhlonius sp. nov. a novel murine urease-negative Helicobacter species. J. Clin. Microbiol. 2001, 39:3920-3926.
75. Franklin C.L., Riley L.K., Livingston R.S., Beckwith C.S., Besch-Williford C.L., Hook R.R.Jr. Enterohepatic lesions in SCID mice infected with. Helicobacter bilis. Lab. Anim. Sci. 1998, 48:334-339.
76. Franklin C.L., Riley L.K., Livingston R.S., Beckwith C.S., Hook R.R.Jr., Besch-Williford C.L., et al. Enteric lesions in SCID mice infected with quot;Helicobacter typhlonicus quot; a novel urease-negative Helicobacter species. Lab. Anim. Sci. 1999, 49:496-505.
77. Garcia A., Iirig M.M, Whary M.T., Feng Y, Xu S., Rogers A.B., et al. A mouse model of hepatocellular carcinoma: dominant responsiveness in Helicobacter hepaticus-induczd liver cancer in Fl hybrid male mice (abstract). Gastroenterology 2004, 126:A40-A41.
78. Garcia A., Rogers A.B., Ihrig M., Fox J.G. A genetic basis for hepatocellular cancer: dominant responsiveness in Helicobacter hepati-cus induced liver cancer in Fl hybrid B6AF1 male mice. Helicobacter 2003, 8:441.
79. Ge Z., Doig P., Fox J.G. Characterization of proteins in the outer membrane preparation of a murine pathogen. Helicobacter bilis. Infect. Immun. 2001, 69:3502-3506.
80. Ge Z., Feng Y, White D.A., Schauer D.B., Fox J.G. Genomic characterization of Helicobacter hepaticus: ordered cosmid library and comparative sequence analysis. FEMS Microbiol. Lett. 2001, 204:147-153.
81. Ge Z., White D.A., Whary M.T., Fox J.G. Fluorogenic PCR-based quantitative detection of a murine pathogen Helicobacter hepaticus. J. Clin. Microbiol. 2001, 39:2598-2602.
82. Gobert A.P., Mersey B.D., Cheng Y, Blumberg D.R., Newton J.C., Wilson K.T. Cutting edge: urease release by Helicobacter pylori stimulates macrophage inducible nitric oxide synthase. J. Immunol. 2002, 168:6002-6006.
83. Goto K., Ishihara K.I., Kuzuoka A., Ohnishi Y, Itoh T. Contamination of transplantable human tumor-bearing lines by Helicobacter hepaticus and its elimination. J. Clin. Microbiol. 2001, 39:3703-3704.
84. Hailey J.R., Haseman J.K., Bucher J.R., Radovsky A.E., Malarkey D.E., Miller R.T., et al. Impact of Helicobacter hepaticus infection in B6C3F1 mice from twelve National Toxicology Program two-year carcino-genesis studies. Toxicol. Pathol. 1998, 26:602-611.
85. Hall P.A., Coates P.J., Ansari B., Hopwood D. Regulation of cell number in the mammalian gastrointestinal tract: the importance of apop-tosis. J. Cell Sci. 1994, 107:3569-3577. (Pt 12).
86. Hodzic E., McKisic M., Feng S., Barthold S.W. Evaluation of diagnostic methods for Helicobacter bilis infection in laboratory mice. Comp. Med. 2001, 51:406-412.
87. Ihrig M., Schrenzel M.D., Fox J.G. Differential susceptibility to hepatic inflammation and proliferation in AXB recombinant inbred mice chron-ically infected with. Helicobacter hepaticus. Am. J. Pathol. 1999, 155:571-582.
88. Isfort R.J., Cody D.B., Richards W.G., Yoder B.K., Wilkinson J.E., Woychik R.P. Characterization of growth factor responsiveness and alterations in growth factor homeostasis involved in the tumorigenic conver-sion of mouse oval cells. Growth Factors 1998, 15:81-94.
89. Ismail H.F., Fick P., Zhang J., Lynch R.G., Berg D.J. Depletion of neutrophils in IL-10 (-/-) mice delays clearance of gastric Helicobacter infection and decreases the Th1 immune response to Helicobacter. J. Immunol. 2003, 170:3782-3789.
90. Ismail H.F, Zhang J., Lynch R.G., Wang Y., Berg D.J. Role for complement in development of Helicobacter-induced gastritis in interleukin-10-deficient mice. Infect. Immun. 2003, 71:7140-7148.
91. Jenks P.J., Jeremy A.H., Robinson P.A., Walker M.M., Crabtree J.E. Long-term infection with Helicobacter felis and inactivation of the tumour suppressor gene p53cumulatively enhance the gastric mutation frequency in Big Blue transgenic mice. J. Pathol. 2003, 201 596-602.
92. Jiang H.Q., Kushnir N., Thurnheer M.C., Bos N.A., Cebra J.J. Monoassociation of SCID mice with Helicobacter muridarum but not four other enterics provokes IBD upon receipt of T cells. Gastroenterology 2002, 122:1346-1354.
93. Jiang W., Baker H.J., Smith B.F Mucosal immunization with helicobacter CpG DNA and cholera toxin is protective. Infect. Immun. 2003, 71:40-46.
94. Karttunen R., Karttunen T., Ekre H.P., MacDonald T.T. Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacter pylori positive and negative gastritis. Gut 1995, 36:341-345.
95. Kendall L.V., Feng S., Hodzic E., Freet K., Barthold S.W. Use of the PI67 recombinant antigen for serodiagnosis of Helicobacter bilis. Comp. Med. 2004, 54:44-48.
96. Kiehlbauch J.A., Brenner D.J., Cameron D.N., Steigerwalt A.G., Makowski J.M., Baker C.N., et al. Genotypic and phenotypic characterization of Helicobacter cinaedi and Helicobacter fennelliae strains isolated from humans and animals. J. Clin. Microbiol. 1995, 33:2940-2947.
97. Kongshavn P.A. Genetic control of resistance to Listeria infection. Curr. Top. Microbiol. Immunol. 1986, 124:67-85.
98. Kuhn R., Lohler J., Rennick D., Rajewsky K., Muller W Interleukin-10-deficient mice develop chronic enterocolitis. Cell 1993, 75:263-274.
99. Kullberg M.C., Andersen J.F, Gorelick P.L., Caspar P., Suerbaum S., Fox J.G., et al. Induction of colitis by a CD4+ T cell clone specific for a bacterial epitope. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:15830-15835.
100. Kullberg M.C., Jankovic D., Gorelick P.L., Caspar P., Letterio J.J., Cheever A.W, et al. Bacteria-triggered CD4 (+) T regulatory cells suppress Helicobacter hepaticus-induced colitis. J. Exp. Med. 2002, 196:505-515.
101. Kullberg M.C., Ward J.M., Gorelick P.L., Caspar P., Hieny S., Cheever A., et al. Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-lO) -deficient mice through an IL-12-and gamma interferon-dependent mechanism. Infect. Immun. 1998, 66:5157-5166.
102. Lee A., Fox J.G., Otto G., Murphy J. A small animal model of human Helicobacter pylori active chronic gastritis. Gastroenterology 1990, 99:1315-1323.
103. Lee A., O'Rourke J., De Ungria M.C., Robertson B., Daskalopoulos G., Dixon M.F. A standardized mouse model of Helicobacter pylori infection: introducing the Sydney strain. Gastroenterology 1997, 112:1386-1397.
104. Lee A., Phillips M.W., O'Rourke J.L., Paster B.J., Dewhirst F.E., Fraser G.J., et al. Helicobacter muridarum sp. nov. a microaerophilic helical bacterium with a novel ultrastructure isolated from the intestinal mucosa of rodents. Int. J. Syst. Bacteriol. 1992, 42:27-36.
105. Li C., Wong W.H. Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:31-36.
106. Li X., Fox J.G., Whary M.T., Yan L., Shames B., Zhao Z. SCID/NCr mice naturally infected with Helicobacter hepaticus develop progressive hepatitis proliferative typhlitis and colitis. Infect. Immun. 1998, 66:5477-5484.
107. Livingston R.S., Myles M.H., Livingston B.A., Criley J.M., Franklin C.L. Sex influence on chronic intestinal inflammation in Helicobacter hepaticus-infected A/JCr mice. Comp. Med. 2004, 54:301-308.
108. Livingston R.S., Riley L.K. Diagnostic testing of mouse and rat colonies for infectious agents. Lab. Anim. 2003, 32:44-51.
109. Livingston R.S., Riley L.K., Besch-Williford C.L., Hook R.R., Franklin C.L. Transmission of Helicobacter hepaticus infection to sentinel mice by contaminated bedding. Lab. Anim. Sci. 1998, 48:291-293.
110. Livingston R.S., Riley L.K., Hook R.R., Besch-Williford C.L., Franklin C.L. Cloning and expression of an immunogenic mem-brane-associated protein of Helicobacter hepaticus for use in an enzyme-linked immunosorbent assay. Clin. Diagn. Lab. Immunol. 1999, 6:745-750.
111. Livingston R.S., Riley L.K., Steffen E.K., Besch-Williford C.L., Hook R.R.Jr., Franklin C.L. Serodiagnosis of Helicobacter hepaticus infection in mice by an enzyme-linked immunosorbent assay. J. Clin. Microbiol. 1997, 35:1236-1238.
112. Luperchio S., Tamir S., Tannenbaum S.R. No-induced oxidative stress and glutathione metabolism in rodent and human cells. Free Radie. Biol. Med. 1996, 21:513-519.
113. Maggio-Price L., Shows D., Waggie K., Burich A., Zeng W, Escobar S., et al. Helicobacter bilis infection accelerates and H. hepaticus infec-tion delays the development of colitis in multiple drug resistance-deficient (mdrla-/-) mice. Am. J. Pathol. 2002, 160:739-751.
114. Malkinson A.M., Nesbitt M.N., Skamene E. Susceptibility to urethan-induced pulmonary adenomas between A/J and C57BL/6J mice: use of AXB and BXA recombinant inbred lines indicating a three-locus genetic model. J. Natl. Cancer Inst. 1985, 75:971-974.
115. Malo D., Vidal S.M., Hu J., Skamene E., Gros P. High-resolu-tion linkage map in the vicinity of the host resistance locus. Beg. Genomics 1993, 16:655-663.
116. Maloy K.J., Salaun L., Cahill R., Dougan G., Saunders N.J., Powrie F. CD4+CD25+ T (R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. 2003, 197:111-119.
117. Manly K., Dudmore R., Jr Kohler G. Map manager QT: a program for genetic mapping of mendelian and quantitiative trait loci 1997.
118. Mannick E.E., Bravo L.E., Zarama G., Realpe J.L., Zhang X.J., Ruiz B., et al. Inducible nitric oxide synthase nitrotyrosine and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. Cancer Res. 1996, 56:3238-3243.
119. Marshall B., Warren J. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet 1983, 1:1273-1275.
120. Marshall B.J. Helicobacter pylori in peptic ulcer: have Koch's postu-lates been fulfilled?. Ann. Med. 1995, 27:565-568.
121. Matsukura N., Yokomuro S., Yamada S., Tajiri T., Sundo T., Hadama T., et al. Association between Helicobacter bilis in bile and biliary tract malignancies: H. bilis in bile from Japanese and Thai patients with benign and malignant diseases in the biliary tract. Jpn. J. Cancer Res. 2002, 93:842-847.
122. Maurer K.J., Ihrig M.M., Ng V., Bouchard G., Carey M.C., Fox J.G. Non-Helicobacter pylori enterohepatic Helicobacter spp. infection is essential for cholesterol gallstone formation in gallstone prone C57/L mice fed a lithogenic diet for eight weeks (abstract). Gastroenterology 2004, 126:A40.
123. Maurer K.J., Ihrig M.M., Rogers A.B., Ng V., Bouchard G., Leonard M.R., Carey M.C., Fox J.G. Identification of cholelithogenic entero-hepatic Helicobacter species and their role in murine cholesterol gallstone formation. Gastroenterology 2005, 128:1023-1033.
124. Maurer K.J., Rogers A.B., Ge Z., Wiese A.J., Carey M.C., Fox J.G. Helicobacter pylori and cholesterol gallstone formation in C57L/J mice: a prospective study. Am.J Physiol Gastrointest. Liver Physiol 2006, 290:G175-G182.
125. Mohammadi M., Czinn S., Redline R., Nedrud J. Helicobacter-specific cell-mediated immune responses display a predominant Thl phenotype and promote a delayed-type hypersensitivity response in the stomachs of mice. J. Immunol. 1996, 156:4729-4738.
126. Mohammadi M., Redline R., Nedrud J., Czinn S. Role of the host in pathogenesis of Helicobacter-associated gastritis: H.felis infection of inbred and congenic mouse strains. Infect. Immun. 1996, 64:238-245.
127. Moss S.F., Calam J., Agarwal B., Wang S., Holt P.R. Induction of gastric epithelial apoptosis by Helicobacter pylori. Gut 1996, 38:498-501.
128. Moura S.B., Mendes E.N., Queiroz D.M., Nicoli J.R., Cabrai M.M., Magalhaes R.R., et al. Microbiological and histological study of the gastrointestinal tract of germ-free mice infected with Helicobacter trogon-tum. Res. Microbiol. 1999, 150:205-212.
129. Moura S.B., Queiroz D.M., Rocha G.A., Comunian L.B., Cara D.C. Hepatic changes in mice chronically infected with Helicobacter trogontum. Braz. J. Med. Biol. Res. 2003, 36:1209-1213.
130. Murata H., Tsuji S., Tsujii M., Fu H.Y., Tanimura H., Tsujimoto M., et al. Helicobacter bilis infection in biliary tract cancer. Aliment Pharmacol Ther. 2004, 20(Suppl 1):90-94.
131. Myles M.H., Livingston R.S., Franklin C.L. Pathogenicity of Helicobacter rodentium in A/JCr and SCID mice. Comp Med 2004, 54:549-557.
132. Myles M.H., Livingston R.S., Livingston B.A., Criley J.M., Franklin C.L. Analysis of gene expression in ceca of Helicobacter hepaticus- infected A/JCr mice before and after development of typhlitis. Infect. Immun. 2003, 71:3885-3893.
133. Nilsson H.O., Ouis I.S., Stenram U., Ljungh A., Moran A.P., Wadstrom T., Al-Soud W.A. High prevalence of Helicobacter species detected in laboratory mouse strains by multiplex PCR-denaturing gradient gel elec-trophoresis and pyrosequencing. J. Clin. Microbiol. 2004, 42:3781-3788.
134. Noach L.A., Bosma N.B., Jansen J., Hoek F.J., van Deventer S.J., Tytgat G.N. Mucosal tumor necrosis factor-alpha interleukin-1 beta and interleukin-8 production in patients with Helicobacter pylori infec-tion. Scand. J. Gastroenterol. 1994, 29:425-429.
135. Nyska A., Maronpot R.R., Eldridge S.R., Haseman J.K., Hailey J.R. Alteration in cell kinetics in control B6C3F1 mice infected with Helicobacter hepaticus. Toxicol. Pathol. 1997, 25:591-596.
136. On S.L. Identification methods for campylobacters helicobacters and related organisms. Clin. Microbiol. Rev. 1996, 9:405-422.
137. Patterson M.M., Schrenzel M.D., Feng Y, Xu S., Dewhirst F.E., Paster B.J., et al. Helicobacter aurati sp. nov. a urease-positive Helicobacter species cultured from gastrointestinal tissues of Syrian hamsters. J. Clin. Microbiol. 2000, 38:3722-3728.
138. Phillips M.W., Lee A. Isolation and characterization of a spiral bacterium from the crypts of rodent gastrointestinal tracts. Appl. Environ. Microbiol. 1983, 45:675-683.
139. Queiroz D.M., Contigli C., Coimbra R.S., Nogueira A.M., Mendes E.N., Rocha G.A., et al. Spiral bacterium associated with gastric ileal and caecal mucosa of mice. Lab. Anim. 1992, 26:288-294.
140. Riley L.K., Franklin C.L., Hook R.R., Besch-Williford C. Identification of murine helicobacters by PCR and restriction enzyme analyses. J. Clin. Microbiol. 1996, 34:942-946.
141. Robertson B.R., O'Rourke J.L., Vandamme P., On S.L., Lee A. Helicobacter ganmani sp. nov. a urease-negative anaerobe isolated from the intestines of laboratory mice. Int. J. Syst. Evol. Microbiol. 2001, 51:1881-1889.
142. Rogers A., Boutin S., Whary M., Sundina N., Ge Z., Cormier K., et al. Progression of chronic hepatitis and preneoplasia in Helicobacter hepaticus-Infected A/JCr mice. Toxicol. Pathol. 2004, 32:668-677.
143. Rogers A.B., Fox J.G. Inflammation and Cancer. I. Rodent models of infectious gastrointestinal and liver cancer. Am. J. Physiol. Gastrointest. Liver Physiol. 2004, 286:G361-G366.
144. Roth K.A., Kapadia S.B., Martin S.M., Lorenz R.G. Cellular immune responses are essential for the development of Helicobacter felis- associated gastric pathology. J. Immunol. 1999, 163:1490-1497.
145. Russell R.J., Haines D.C., Anver M.R., Battles J.K., Gorelick P.L., Blumenauer L.L., et al. Use of antibiotics to prevent hepatitis and typhlitis in male scid mice spontaneously infected with Helicobacter hepaticus. Lab. Anim. Sci. 1995, 45:373-378.
146. Saunders K.E., McGovern K.J., Fox J.G. Use of pulsed-field gel electrophoresis to determine genomic diversity in strains of Helicobacter hepaticus from geographically distant locations. J. Clin. Microbiol. 1997, 35:2859-2863.
147. Schauer D.B., Ghori N., Falkow S. Isolation and characterization of quot;Flexispira rappin quot; from laboratory mice. J. Clin. Microbiol. 1993, 31:2709-2714.
148. Schulte-Hermann R., Timmermann-Trosiener L, Schuppler J. Promotion of spontaneous preneoplastic cells in rat liver as a possible expla-nation of tumor production by nonmutagenic compounds. Cancer Res. 1983, 43:839-844.
149. Shames B., Fox J.G., Dewhirst F., Yan L., Shen Z., Taylor N.S. Identification of widespread Helicobacter hepaticus infection in feces in commercial mouse colonies by culture and PCR assay. J. Clin. Microbiol. 1995, 33:2968-2972.
150. Shen Z., Feng Y, Fox J.G. Identification of enterohepatic Helicobacter species by restriction fragment-length polymorphism analysis of the 16S rRNA gene. Helicobacter 2000, 5:121-128.
151. Shen Z., Fox J.G., Dewhirst F.E., Paster B.J., Foltz C.J., Yan L., Shames B., Perry L. Helicobacter rodentium sp. nov. a urease-negative Helicobacter species isolated from laboratory mice. Int. J. Syst. Bacteriol. 1997, 47:627-634.
152. Shen Z., Schauer D.B., Mobley H.L., Fox J.G. Development of a PCR-restriction fragment length polymorphism assay using the nucleotide sequence of the Helicobacter hepaticus urease structural genes ureAB. J. Clin. Microbiol. 1998, 36:2447-2453.
153. Shen Z., Xu S., Dewhirst F.E., Paster B.J., Pena J.A., Modlin I.M., et al. A novel enterohepatic Helicobacter sp. H. mastomyrinus isolated from the liver and intestine of rodents. Helicobacter 2005, 10:59-70.
154. Shomer N.H., Dangler C.A., Marini R.P., Fox J.G. Helicobacter bilis/Helicobacter rodentium co-infection associated with diarrhea in a colony of scid mice. Lab. Anim. Sci. 1998, 48:455-459.
155. Shomer N.H., Dangler C.A., Schrenzel M.D., Fox J.G. Helicobacter bilis-induced inflammatory bowel disease in scid mice with defined flora. Infect. Immun. 1997, 65:4858-4864.
156. Shomer N.H., Dangler C.A., Schrenzel M.D., Whary M.T., Xu S., Feng Y, et al. Cholangiohepatitis and inflammatory bowel disease induced by a novel urease-negative Helicobacter species in A/J and Tac:ICR:HascidfRF mice. Exp. Biol. Med. (Maywood) 2001, 226:420-428.
157. Shomer N.H., Fox J.G., Juedes A.E., Ruddle N.H. Helicobacter-induced chronic active lymphoid aggregates have characteris-tics of tertiary lymphoid tissue. Infect. Immun. 2003, 71:3572-3577.
158. Singh R., Leuratti C., Josyula S., Sipowicz M.A., Diwan B.A., Kasprzak K.S., et al. Lobe-specific increases in malondialdehyde DNA adduct formation in the livers of mice following infection with Helicobacter hepaticus. Carcinogenesis 2001, 22:1281-1287.
159. Singletary K.B., Kloster C.A., Baker D.G. Optimal age at fostering for
160. Sipowicz M.A., Chomarat P., Diwan B.A., Anver M.A., Awasthi Y.C., Ward J.M., et al. Increased oxidative DNA damage and hepatocyte overexpression of specific cytochrome P450isoforms in hepatitis of mice infected with Helicobacter hepaticus. Am. J. Pathol. 1997, 151:933-941.
161. Sipowicz M.A., Weghorst C.M., Shiao Y.H., Buzard G.S., Calvert R.J., Anver M.R., et al. Lack of p53 and ras mutations in Helicobacter hepaticus-induced liver tumors in A/JCr mice. Carcinogenesis 1997, 18:233-236.
162. Skamene E., Gros P., Forget A., Kongshavn P.A., St Charles C., Taylor B.A. Genetic regulation of resistance to intracellular pathogens. Nature 1982, 297:506-509.
163. Solnick J.V., Schauer D.B. Emergence of diverse Helicobacter species in the pathogenesis of gastric and enterohepatic diseases. Clin. Microbiol. Rev. 2001, 14:59-97.
164. Spencer J., Wotherspoon A.C. Gastric MALT lymphoma and Helicobacter pylori. Cancer Surv. 1997, 30:213-231.
165. Steinberg P., Steinbrecher R., Radaeva S., Schumacher P., Dienes H.P., Oesch R, et al. Oval cell lines OC/CDE 6 and OC/CDE 22 give rise to cholangio-cellular and undifferentiated carcinomas after transformation. Lab. Invest. 1994, 71:700-709.
166. Stoicov C., Whary M., Rogers A.B., Lee F.S., Klucevsek K., Li H., et al. Coinfection modulates inflammatory responses and clinical outcome of Helicobacter felis and Toxoplasma gondii infections. J. Immunol. 2004, 173:3329-3336.
167. Suerbaum S., Josenhans C., Sterzenbach T., Drescher B., Brandt P., Bell M., et al. The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:7901-7906.
168. Sutton P., Wilson J., Genta R., Torrey D., Savinainen A., Pappo J., et al. A genetic basis for atrophy: dominant non-responsiveness and helicobacter induced gastritis in F (l) hybrid mice. Gut 1999, 45:335-340.
169. Taylor N., Xu S., Ng V., Dewhirst F., Fox J. High prevalence of Helicobacter spp. in mouse research colonies in the United States Europe and Asia. Contemp. Top. Lab. Anim.Sci. 2004, 43:58-59.
170. Thompson L.J., Danon S.J., Wilson J.E., O'Rourke J.L., Salama N.R., Falkow S., et al. Chronic Helicobacter pylori infection with Sydney strain 1 and a newly identified mouse adapted strain (Sydney strain 2000) in C57BL/6 and BALB/c mice. Infect. Immun. 2004, 72:4668-4679.
171. Tomczak M.E, Erdman S.E., Poutahidis T., Rogers A.B., Holcombe H., Plank B., et al. NF-kappa B is required within the innate immune system to inhibit microflora-induced colitis and expression of IL-12 p40. J. Immunol. 2003, 171:1484-1492.
172. Touati E., Michel V., Thiberge J.M., Wuscher N., Huerre M., Labigne A. Chronic Helicobacter pylori infections induce gastric mutations in mice. Gastroenterology 2003, 124:1408-1419.
173. Uppu R.M., Cueto R., Squadrito G.L., Salgo M.G., Pryor W.A. Competitive reactions of peroxynitrite with 2'-deoxyguanosine and 78-dihydro-8-oxo-2 prime;-deoxyguanosine (8-oxodG): relevance to the forma-tion of 8-oxodG in DNA exposed to peroxynitrite. Free Radic. Biol. Med. 1996, 21:407-411.
174. Vandamme P., Harrington C.S., Jalava K., On S.L. Misidentifying helicobacters: the Helicobacter cinaedi example. J. Clin. Microbiol. 2000, 38:2261-2266.
175. von Freeden-Jeffry U., Davidson N., Wiler R., Fort M., Burdach S., Murray R. IL-7 deficiency prevents development of a non-T cell non-B cell-mediated colitis. J. Immunol. 1998, 161:5673-5680.
176. Wagner S., Beil W, Westermann J., Logan R.P., Bock C.T., Trautwein C., et al. Regulation of gastric epithelial cell growth by Helicobacter pylori: offdence for a major role of apoptosis. Gastroenterology 1997, 113:1836-1847.
177. Wang T.C., Dangler C.A., Chen D., Goldenring J.R., Koh T., Raychowdhury R., et al. Synergistic interaction between hypergas-trinemia and Helicobacter infection in a mouse model of gastric cancer. Gastroenterology 2000, 118:36-47.
178. Ward J.M., Anver M.R., Haines D.C., Benveniste R.E. Chronic active hepatitis in mice caused by Helicobacter hepaticus. Am. J. Pathol. 1994, 145:959-968.
179. Ward J.M., Anver M.R., Haines D.C., Melhorn J.M, Gorelick P., Yan L., et al. Inflammatory large bowel disease in immunodeficient mice naturally infected with Helicobacter hepaticus. Lab. Anim. Sci. 1996, 46:15-20.
180. Ward J.M., Fox J.G., Anver M.R., Haines D.C., George C.V., Collins M.J., et al. Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species. J. Natl. Cancer Inst. 1994, 86:1222-1227.
181. Weghorst C.M., Pereira M.A., Klaunig J.E. Strain differences in hepatic tumor promotion by phenobarbital in diethylnitrosamine-and dimethyl-nitrosamine-initiated infant male mice. Carcinogenesis 1989, 10:1409-1412.
182. Whary M., Shi H., White H., Nagler-Anderson C., Fox J. Th2 responses to the helminth Heligmosomoides polygyrus reduce Thl-promoted epithelial hyperplasia in a mouse model of Helicobacter hepaticus-associated inflammatory bowel disease (IBD). Gastroenterology 2001, 120:A194.
183. Whary M.T., Cline J., King A., Ge Z., Shen Z., Sheppard B., et al. Long-term colonization levels of Helicobacter hepaticus in the cecum of hepatitis-prone A/JCr mice are significantly lower than those in hepatitis-resistant C57BL/6 mice. Comp. Med. 2001, 51:413-417.
184. Whary M.T., Cline J.H., King A.E., Corcoran C.A., Xu S., Fox J.G. Containment of Helicobacter hepaticus by use of husbandry practices. Comp. Med. 2000, 50:78-81.
185. Whary M.T., Cline J.H., King A.E., Hewes K.M., Chojnacky D., Salvarrey A., et al. Monitoring sentinel mice for Helicobacter hepaticus H. rodentium and H. bilis infection by use of polymerase chain reaction analysis and serologie testing. Comp. Med. 2000, 50:436-443.
186. Whary M.T., Fox J.G. Natural and experimental Helicobacter infections. Comp. Med. 2004, 54:128-158.
187. Whary M.T., Fox J.G. Thl-mediated pathology in mouse models of human disease is ameliorated by concurrent Th2 responses to parasite antigens. Curr. Top. Med. Chem. 2004, 4:531-538.
188. Whary M.T., Morgan T.J., Dangler C.A., Gaudes K.J., Taylor N.S., Fox J.G. Chronic active hepatitis induced by Helicobacter hepati-cus in the A/JCr mouse is associated with a Thl cell-mediated immune response. Infect. Immun. 1998, 66:3142-3148.
189. WHO IARC Working Group on the Evaluation of Carcinogenic Risk to Humans in Schistosomes liver flukes and Helicobacter pylori 1994, Lyon.
190. Won Y.S., Yoon J.H., Lee C.H., Kim B.H., Hyun B.H., Choi Y.K. Helicobacter muricola sp. nov. a novel Helicobacter species isolated from the ceca and feces of Korean wild mouse (Mus musculus molossinus). FEMS Microbiol. Lett. 2002, 209:45-51.
191. Ye Y.L., Suen J.L., Chen Y.Y., Chiang B.L. Phenotypic and functional analysis of activated B cells of autoimmune NZB x NZW Fl mice. Scand. J. Immunol. 1998, 47:122-126.
192. Young V.B., Knox K.A., Pratt J.S., Cortez J.S., Mansfield L.S., Rogers A.B., et al. In vitro and in vivo characterization of Helicobacter hepaticus cytolethal distending toxin mutants. Infect. Immun. 2004, 72:2521-2527.
193. Yumoto N., Furukawa M., Kurosu K., Mikata A. A particular characteristic of IgH complementarity-determining region 3 suggests autore-active B-cell origin of primary gastric B-cell lymphomas. Lab. Invest. 1998, 78:261-268.