Helicobacter-induced chronic active lymphoid aggregates have characteristics of tertiary lymphoid tissue

Infection and Immunity

Volumn 71, Issue 6, 2003, Pages 3572-3577

  Shomer, Nirah H ^a,d,e   Fox, James G ^b   Juedes, Amy E ^c,f   Ruddle, Nancy H ^c  

^a YALE UNIVERSITY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Laboratory Animal Science Center   (United States)

^e BOSTON UNIVERSITY   (United States)

^f LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCL21; CHEMOKINE RECEPTOR CXCL13; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; BACTERIAL STRAIN; CELL SELECTION; CHRONIC ACTIVE HEPATITIS; CONTROLLED STUDY; ENDOTHELIUM CELL; FLUORESCENCE; HELICOBACTER; HYPOTHESIS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATION; INFLAMMATORY INFILTRATE; LIVER CELL; LYMPHOID TISSUE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, SURFACE; AUTOIMMUNITY; CELL ADHESION MOLECULES; CELL AGGREGATION; CHEMOKINES, CC; CHEMOKINES, CXC; HELICOBACTER INFECTIONS; HEPATITIS, CHRONIC; IMMUNOGLOBULINS; LIVER; LYMPHOID TISSUE; MEMBRANE PROTEINS; MICE; MUCOPROTEINS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0038103829     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.6.3572-3577.2003     Document Type: Article

References (27)

1. Berek, C., and H. J. Kim. 1997. B-cell activation and development within chronically inflamed synovium in rheumatoid and reactive arthritis. Semin. Immunol. 9:261-268.
2. Bistrup, A., S. Bhakta, J. K. Lee, Y. Y. Belov, M. D. Gunn, F. R. Zuo, C. C. Huang, R. Kannagi, S. D. Rosen, and S. Hemmerich. 1999. Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. J. Cell Biol. 145:899-910.
3. Bowman, K. G., B. N. Cook, C. L. de Graffenried, and C. R. Bertozzi. 2001. Biosynthesis of L-selectin ligands: sulfation of sialyl Lewis x-related oligosaccharides by a family of GlcNAc-6-sulfotransferases. Biochemistry 40:5382-5391.
4. De Togni, P., J. Goellner, N. H. Ruddle, P. R. Streeter, A. Fick, S. Mariathasan, S. C. Smith, R. Carlson, L. P. Shornick, J. Strauss-Schoenberger, et al. 1994. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 264:703-707.
5. Dogan, A., M. Du, A. Koulis, M. J. Briskin, and P. G. Isaacson. 1997. Expression of lymphocyte homing receptors and vascular addressins in lowgrade gastric B-cell lymphomas of mucosa-associated lymphoid tissue. Am. J. Pathol. 151:1361-1369.
6. Hanninen, A., C. Taylor, P. R. Streeter, L. S. Stark, J. M. Sarte, J. A. Shizuru, O. Simell, and S. A. Michie. 1993. Vascular addressins are induced on islet vessels during insulitis in nonobese diabetic mice and are involved in lymphoid cell binding to islet endothelium. J. Clin. Investig. 92:2509-2515.
7. Hatz, R. A., G. Rieder, M. Stolte, E. Bayerdorffer, G. Meimarakis, F. W. Schildberg, and G. Enders. 1997. Pattern of adhesion molecule expression on vascular endothelium in Helicobacter pylori-associated antral gastritis. Gastroenterology 112:1908-1919.
8. Hemmerich, S., A. Bistrup, M. S. Singer, A. van Zante, J. K. Lee, D. Tsay, M. Peters, J. L. Carminati, T. J. Brennan, K. Carver-Moore, M. Leviten, M. E. Fuentes, N. H. Ruddle, and S. D. Rosen. 2001. Sulfation of L-selectin ligands by an HEV-restricted sulfotransferase regulates lymphocyte homing to lymph nodes. Immunity 15:237-247.
9. Hillan, K. J., K. E. Hagler, R. N. MacSween, A. M. Ryan, M. E. Renz, H. H. Chiu, R. K. Ferrier, G. L. Bird, A. P. Dhillon, L. D. Ferrell, and S. Fong. 1999. Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease. Liver 19:509-518.
10. Hiraoka, N., B. Petryniak, J. Nakayama, S. Tsuboi, M. Suzuki, J. C. Yeh, D. Izawa, T. Tanaka, M. Miyasaka, J. B. Lowe, and M. Fukuda. 1999. A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis(x), an L-selectin ligand displayed by CD34. Immunity 11:79-89.
11. Hjelmstrom, P., J. Fjell, T. Nakagawa, R. Sacca, C. A. Cuff, and N. H. Ruddle. 2000. Lymphoid tissue homing chemokines are expressed in chronic inflammation. Am. J. Pathol. 156:1133-1138.
12. Ihrig, M., M. D. Schrenzel, and J. G. Fox. 1999. Differential susceptibility to hepatic inflammation and proliferation in AXB recombinant inbred mice chronically infected with Helicobacter hepaticus. Am. J. Pathol. 155:571-582.
13. Kasajima, T., M. Yamakawa, and Y. Imai. 1987. Immunohistochemical study of intrathyroidal lymph follicles. Clin. Immunol. Immunopathol. 43:117-128.
14. Kratz, A., A. Campos-Neto, M. S. Hanson, and N. H. Ruddle. 1996. Chronic inflammation caused by lymphotoxin is lymphoid neogenesis. J. Exp. Med. 183:1461-1472.
15. Lee, A., J. G. Fox, G. Otto, and J. Murphy. 1990. A small animal model of human Helicobacter pylori active chronic gastritis. Gastroenterology 99:1315-1323.
16. Luther, S. A., T. Lopez, W. Bai, D. Hanahan, and J. G. Cyster. 2000. BLC expression in pancreatic islets causes B cell recruitment and lymphotoxindependent lymphoid neogenesis. Immunity 12:471-481.
17. Mazzucchelli, L., A. Blaser, A. Kappeler, P. Scharli, J. A. Laissue, M. Baggiolini, and M. Uguccioni. 1999. BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphoma. J. Clin. Investig. 104:R49-R54.
18. Mebius, R. E., P. R. Streeter, S. Michie, E. C. Butcher, and I. L. Weissman. 1996. A developmental switch in lymphocyte homing receptor and endothelial vascular addressin expression regulates lymphocyte homing and permits CD4+ CD3- cells to colonize lymph nodes. Proc. Natl. Acad. Sci. USA 93:11019-11024.
19. Mehal, W. Z., A. E. Juedes, and I. N. Crispe. 1999. Selective retention of activated CD8+ T cells by the normal liver. J. Immunol. 163:3202-3210.
20. Ruddle, N. H. 1999. Lymphoid neo-organogenesis: lymphotoxin's role in inflammation and development. Immunol. Res. 19:119-125.
21. Shomer, N. H., C. A. Dangler, M. D. Schrenzel, M. T. Whary, S. Xu, Y. Feng, B. J. Paster, F. E. Dewhirst, and J. G. Fox. 2001. Cholangiohepatitis and inflammatory bowel disease induced by a novel urease-negative Helicobacter species in A/J and Tac:ICR:HascidfRF mice. Exp. Biol. Med. (Maywood) 226:420-428.
22. Shomer, N. H., C. A. Dangler, M. T. Whary, and J. G. Fox. 1998. Experimental Helicobacter pylori infection induces antral gastritis and gastric mucosa-associated lymphoid tissue in guinea pigs. Infect. Immun. 66:2614-2618.
23. Steere, A. C., P. H. Duray, and E. C. Butcher. 1988. Spirochetal antigens and lymphoid cell surface markers in Lyme synovitis. Comparison with rheumatoid synovium and tonsillar lymphoid tissue. Arthritis Rheum. 31:487-495.
24. Wang, G., P. G. Boulton, N. W. Chan, M. M. Palcic, and D. E. Taylor. 1999. Novel Helicobacter pylori alpha1,2-fucosyltransferase, a key enzyme in the synthesis of Lewis antigens. Microbiology 145(Pt 11):3245-3253.
25. Ward, J. M., J. G. Fox, M. R. Anver, D. C. Haines, C. V. George, M. J. Collins, Jr., P. L. Gorelick, K. Nagashima, M. A. Gonda, R. V. Gilden, et al. 1994. Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species. J. Natl. Cancer Inst. 86:1222-1227.
26. Yasoshima, M., Y. Nakanuma, K. Tsuneyama, J. Van de Water, and M. E. Gershwin. 1995. Immunohistochemical analysis of adhesion molecules in the microenvironment of portal tracts in relation to aberrant expression of PDC-E2 and HLA-DR on the bile ducts in primary biliary cirrhosis. J. Pathol. 175:319-325.
27. Yoneyama, H., K. Matsuno, Y. Zhang, M. Murai, M. Itakura, S. Ishikawa, G. Hasegawa, M. Naito, H. Asakura, and K. Matsushima. 2001. Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease. J. Exp. Med. 193:35-49.