A manganese-superoxide dismutase/catalase mimetic extends survival in a mouse model of human prion disease

Free Radical Biology and Medicine

Volumn 45, Issue 2, 2008, Pages 184-192

  Brazier, Marcus W ^a,b   Doctrow, Susan R ^c   Masters, Colin L ^a,b   Collins, Steven J ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^c Proteome Systems   (United States)

Author keywords

Antioxidants; Free radicals; Manganese; Prion diseases; Superoxide dismutase; Therapy; Transmissible spongiform encephalopathy

Indexed keywords

ANTIOXIDANT; CATALASE; EUK 189; MANGANESE SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN REGION; CONTROLLED STUDY; DRUG EFFICACY; DRUG STRUCTURE; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN CARBONYLATION; SURVIVAL;

ANIMALS; ANTIOXIDANTS; BIOMIMETICS; BLOTTING, WESTERN; BRAIN; CATALASE; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; ORGANOMETALLIC COMPOUNDS; PRION DISEASES; PRIONS; PROTEIN CARBONYLATION; SALICYLATES; SUPEROXIDE DISMUTASE;

ANIMALIA; MUS;

EID: 44649107650     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.04.006     Document Type: Article

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