Expression of inducible nitric oxide synthase in the brains of scrapie-infected mice

Journal of NeuroVirology

Volumn 4, Issue 4, 1998, Pages 445-450

  Ju, Won Kyu ^a   Park, Kyu Jin ^a   Choi, Eun Kyoung ^a   Kim, Jin ^b   Carp, Richard I ^c   Wisniewski, Henry M ^c   Kim, Yong Sun ^a  

^a Hallym University   (South Korea)

^b The Catholic University of Korea College of Medicine   (South Korea)

^c NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

Author keywords

Astrocyte; iNOS; Scrapie; TSE

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA; NITRIC OXIDE SYNTHASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN INFECTION; CONTROLLED STUDY; DEGENERATIVE DISEASE; FEMALE; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; SCRAPIE; SCRAPIE AGENT;

ANIMALIA; SCRAPIE PRION;

EID: 0031876450     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550289809114544     Document Type: Article

References (24)

1. Bredt DS, Snyder SH (1994). Nitric oxide: A physiologic messenger molecule. Ann Rev Biochem 63: 175 - 195.
2. Campbell IL, Eddleston M, Kemper P, Oldstone MBA, Hobbs MV (1994). Activation of cerebral cytokines gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie. J Virol 68: 2383 - 2387.
3. Carp RI, Ye X, Kascsak RJ, Rubenstein R (1994). The nature of the scrapie agent. Biological characteristics of scrapie in different scrapie strain-host combinations. Ann N Y Acad Sci 724: 221 - 234.
4. Chomczynski P, Sacchi N (1987). Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction. Analyt Biochem 162: 156 - 159.
5. Diedrich JF, Bendheim PE, Kim YS, Carp RI, Hasse TA (1991). Scrapie-associated prion protein accumulates in astrocytes during scrapie infection. Proc Natl Acad Sci USA 88: 375 - 379.
6. Kim YS, Carp RI, Callahan SM, Wisniewski HM (1990). Incubation periods and histopathological changes in mice injected sterotaxically in different brain areas with the 87V scrapie strain. Acta Neuropathol (Berl) 80: 388 - 392.
7. Kong LY, Mcmillian MK, Maronpot R, Hong JS (1996). Protein tyrosine kinase inhibitors suppress the production of nitric oxide in mixed glia, microglia-enriched or astrocyte-enriched cultures. Brain Res 729: 102 - 109.
8. Korproski H, Yong MZ, Ellen HK, Nigel F, Lucy R, Zhen FF, Cathleen H, Bernhard D (1993). In vivo expression of inducible nitric oxide synthase in experimentally induced neurologic diseases. Proc Natl Acad Sci USA 90: 3024 - 3027.
9. Lowenstein CJ, Snyder SH (1992). Nitric oxide, a novel biologic messenger. Cell 70: 705 - 707.
10. Manuelidis L (1994). Dementia, neurodegeneration, and viral mechanisms of disease from the perspective of human transmissible encephalopathies. Ann N Y Acad Sci 724: 259 - 281.
11. Manuelidis L (1997). Evolution of a strain of CJD that induces BSE-like plaques. Science 277: 94 - 98.
12. Marietta MA (1993). Nitric oxide synthase structure and mechanism. J Biol Chem 26: 12231 - 12234.
13. Moncada S, Palmer DMJ, Higgs EA (1991). Nitric Oxide: Physiology, Pathology, and Pharmacology. Pharmacological Rev 43: 109 - 142.
14. Nathan C (1992). Nitric oxide as a secretory product of mammalian cells. FASEB 6: 3051 - 3064.
15. Ovadia H, Rosenmann H, Shezen E, Halimi M, Ofran I, Gabizon R (1996). Effect of scrapie infection on the activity of neuronal nitric-oxide synthase in brain and neuroblastoma cells. J Biol Chem 271: 16856 - 16861.
16. Prusiner SB (1987). Prions and neurodegenerative diseases. New Engl J Med 317: 1571 - 1581.
17. Rainer M, Graeme B, John R, Martin L (1994). Inducible nitric oxide synthase from human articular chrondrocytes: cDNA cloning and analysis of mRNA expression. Biochem Biophys Acta 1208: 145 - 150.
18. Sean M, Martha LS, Luis A, Agustina G, Douglas LF, Elena G, Donald JR, Dahlai MG, Joan PS (1993). Synthesis of nitric oxide in CNS glial cells. TINS 16: 323 - 328.
19. Selmaj KW, Farooq M, Norton T, Raine CS, Brosnan CF (1990). Proliferation of astrocytes in vitro in response to cytokines: A primary role for tumor necrosis factor. J Immunol 144: 129 - 135.
20. Shankar V, Dietzschhold B, Koprowski H (1991). Direct entry of rabies virus into the central nervous system with prior local replication. J Virol 65: 2736 - 2738.
21. Southern E (1975). Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 98: 503 - 517.
22. Vigne P, Damasis C, Frelin C (1993). IL1 and TNF-α induce cGMP formation in C6 astrocytoma cells via the nitridergic pathway. Brain Res 606: 332 - 336.
23. Wieesniexvski HM, Wegiel J, Kozielski R (1994). Amyloidosis in prion diseases and cells involved in PrP fibrinogenesis. Ann N Y Acad Sci 724: 191 - 209.
24. Ye X, Carp RL (1994). Scrapie-infected increase in nitric oxide synthase activity in the hamster brain. Abstract in VIIth International Congress of Neuropathology 4: 525.