Amyloid imaging probes are useful for detection of prion plaques and treatment of transmissible spongiform encephalopathies

Journal of General Virology

Volumn 85, Issue 6, 2004, Pages 1785-1790

  Ishikawa, Kensuke ^a   Doh ura, Katsumi ^a,e   Kudo, Yukitsuka ^b   Nishida, Noriyuki ^c   Murakami Kubo, Ikuko ^a   Ando, Yukio ^d   Sawada, Tohru ^b   Iwaki, Toru ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b BF Research Institute Inc   (Japan)

^c NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d KUMAMOTO UNIVERSITY   (Japan)

^e TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 BROMO 2,5 BIS(3 HYDROXYCARBONYL 4 HYDROXY)STYRYLBENZENE; 2 [4' (METHYLAMINO)PHENYL]BENZOTHIAZOLE; AMYLOID; CONGO RED; DIMETHYL SULFOXIDE; PRION PROTEIN; THIOFLAVINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; INCUBATION TIME; INJECTION; MOLECULAR MODEL; MOLECULAR PROBE; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; VIRUS PLAQUE; VIRUS STRAIN; ANIMAL; DRUG ANTAGONISM; PRION;

AMYLOID; ANIMALS; HUMANS; MICE; PRION DISEASES; PRIONS;

EID: 2942672633     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.19754-0     Document Type: Article

References (21)

1. Bacskai, B. J., Klunk, W. E., Mathis, C. A. & Hyman, B. T. (2002). Imaging amyloid-β deposits in vivo. J Cereb Blood Flow Metab 22, 1035-1041.
2. Caughey, B. & Raymond, G. J. (1993). Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells. J Virol 67, 643-650.
3. Caughey, B., Ernst, D. & Race, R. E. (1993). Congo red inhibition of scrapie agent replication. J Virol 67, 6270-6272.
4. Demaerel, P., Baert, A. L., Vanopdenbosch, L., Robberecht, W. & Dom, R. (1997). Diffusion-weighted magnetic resonance imaging in Creutzfeldt-Jakob disease. Lancet 349, 847-848.
5. Doh-ura, K., Mekada, E., Ogomori, K. & Iwaki, T. (2000). Enhanced CD9 expression in the mouse and human brains infected with transmissible spongiform encephalopathies. J Neuropathol Exp Neurol 59, 774-785.
6. Engler, H., Nordberg, A., Blomqvist, G. & 11 other authors (2002). First human study with a benzothiazole amyloid-imaging agent in Alzheimer's disease and control subjects. Neurobiol Aging 23, S429.
7. Fischer, M., Rulicke, T., Raeber, A., Sailer, A., Moser, M., Oesch, B., Brandner, S., Aguzzi, A. & Weissmann, C. (1996). Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J 15, 1255-1264.
8. Hamad, A., Hamad, A., Sokrab, T. E., Momeni, S. & Brown, P. (2001). Iatrogenic Creutzfeldt-Jakob disease at the millennium. Neurology 56, 987.
9. Ingrosso, L., Ladogana, A. & Pocchiari, M. (1995). Congo red prolongs the incubation period in scrapie-infected hamsters. J Virol 69, 506-508.
10. Mathis, C. A., Bacskai, B. J., Kajdasz, S. T. & 8 other authors (2002). A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain. Bioorg Med Chem Lett 12, 295-298.
11. Murakami-Kubo, I., Doh-Ura, K., Ishikawa, K., Kawatake, S., Sasaki, K., Kira, J., Ohta, S. & Iwaki, T. (2004). Quinoline derivatives are therapeutic candidates for transmissible spongiform encephalopathies. J Virol 78, 1281-1288.
12. Murata, T., Shiga, Y., Higano, S., Takahashi, S. & Mugikura, S. (2002). Conspicuity and evolution of lesions in Creutzfeldt-Jakob disease at diffusion-weighted imaging. Am J Neuroradiol 23, 1164-1172.
13. Nishida, N., Harris, D. A., Vilette, D., Laude, H., Frobert, Y., Grassi, J., Casanova, D., Milhavet, O. & Lehmann, S. (2000). Successful transmission of three mouse-adapted scrapie strains to murine neuroblastoma cell lines overexpressing wild-type mouse prion protein. J Virol 74, 320-325.
14. Priola, S. A., Raines, A. & Caughey, W. S. (2000). Porphyrin and phthalocyanine antiscrapie compounds. Science 287, 1503-1506.
15. Prusiner, S. B. (1991). Molecular biology of prion diseases. Science 252, 1515-1522.
16. Race, R. E., Caughey, B., Graham, K., Ernst, D. & Chesebro, B. (1988). Analyses of frequency of infection, specific infectivity, and prion protein biosynthesis in scrapie-infected neuroblastoma cell clones. J Virol 62, 2845-2849.
17. Race, R. E., Priola, S. A., Bessen, R. A., Ernst, D., Dockter, J., Rall,G. F., Mucke, L., Chesebro, B. & Oldstone, M. B. (1995). Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent. Neuron 15, 1183-1191.
18. Skovronsky, D. M., Zhang, B., Kung, M. P., Kung, H. F., Trojanowski, J. Q. & Lee, V. M. (2000). In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 97, 7609-7614.
19. Supattapone, S., Nishina, K. & Rees, J. R. (2002). Pharmacological approaches to prion research. Biochem Pharmacol 63, 1383-1388.
20. Will, R. G., Ironside, J. W., Zeidler, M. & 7 other authors (1996). A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347, 921-925.
21. Yokoyama, T., Kimura, K. M., Ushiki, Y., Yamada, S., Morooka, A., Nakashiba, T., Sassa, T. & Itohara, S. (2001). In vivo conversion of cellular prion protein to pathogenic isoforms, as monitored by conformation-specific antibodies. J Biol Chem 276, 11265-11271.