Internalization of exogenously added memapsin 2 (β-secretase) ectodomain by cells is mediated by amyloid precursor protein

Journal of Biological Chemistry

Volumn 279, Issue 36, 2004, Pages 37886-37894

  Huang, Xiang Ping ^a   Chang, Wan Pin ^a   Koelsch, Gerald ^a,b   Turner III, Robert T ^a,b   Lupu, Florea ^a   Tang, Jordan ^a,c  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b Zapaq Inc   (United States)

^c OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEINS; ECTODOMAIN;

CELLS; ENERGY TRANSFER; FLUORESCENCE; PROTEINS;

BIOCHEMISTRY;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; GLYCOSYLPHOSPHATIDYLINOSITOL; MEMBRANE PROTEIN; PHOSPHOLIPASE C;

ALZHEIMER DISEASE; ARTICLE; CELL LYSATE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVE SITE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; BINDING SITES; CELL LINE; ENDOCYTOSIS; ENDOPEPTIDASES; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 4444283663     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402130200     Document Type: Article

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