Involvement of the Ras/MAPK signaling pathway in the modulation of urokinase production and cellular invasiveness by transforming growth factor-β1 in transformed keratinocytes

Biochemical and Biophysical Research Communications

Volumn 273, Issue 2, 2000, Pages 521-527

  Santibáñez, Juan F ^a,b   Iglesias, Maite ^a   Frontelo, Pilar ^a   Martínez, Jorge ^b   Quintanilla, Miguel ^a  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

ERK; Invasiveness; Keratinocytes; MEK; Motility; Ras; TGF 1; uPA

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; RAS PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UROKINASE;

ARTICLE; CELL INVASION; CELL MOTILITY; CELL TRANSFORMATION; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME REGULATION; ENZYME RELEASE; GENE REPRESSION; HUMAN; HUMAN CELL; KERATINOCYTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0343517552     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.2946     Document Type: Article

References (35)

1. Mignatti P., Rifkin D. R. Physiol. Rev. 73:1993;161-195.
2. Andreasen P. A., Kjoller L., Christensen L., Duffy M. J. Int. J. Cancer. 72:1997;1-22.
3. Busso N., Masur S. K., Lazega D., Waxman S., Ossowski L. J. Cell Biol. 126:1994;259-270.
4. Aguirre-Guiso J. A., Alonso D. F., Farias E. F., Gómez D. E., de Kier Joffè E. B. Eur. J. Biochem. 263:1999;295-304.
5. Hill C. S., Treisman R. Cell. 80:1995;199-211.
6. Minden A., Lin A., McMahon M., Lange-Carter C., Derijard B., Davis R. J., Johnson G. L., Karin M. Science. 266:1994;1719-1723.
7. Farina A. R., Coppa A., Tiberio A., Tacconelli A., Turco A., Colletta G., Gulino A., Mackay A. R. Int. J. Cancer. 75:1998;721-730.
8. Santibáñez J. F., Frontelo P., Iglesias M., Martínez J., Quintanilla M. J. Cell. Biochem. 74:1999;61-73.
9. Festuccia C., Angelucci A., Gravina G. L., Villanova I., Teti A., Albini A., Bologna M. Int. J. Cancer. 85:2000;407-415.
10. Akhurst R. J., Balmain A. J. Pathol. 187:1999;82-90.
11. Oft M., Heider K-H., Beug H. Curr. Biol. 8:1998;1243-1252.
12. Oft M., Peli J., Rudaz C., Schwartz H., Beug H., Reichmann E. Genes Dev. 10:1996;2462-2477.
13. Massagué J. Annu. Rev. Biochem. 67:1998;753-791.
14. Hanafusa H., Ninomiya-Tsuji J., Masuyama N., Nishita M., Fujisawa J., Shibuya H., Matsumoto K., Nishida E. J. Biol. Chem. 274:1999;27161-27167.
15. Hartsough M. T., Frey R. S., Zipfel P. A., Buard A., Cook S. J., McCormick F., Mulder K. M. J. Biol. Chem. 271:1996;22368-22375.
16. Hu P. P., Shen X., Huang D., Liu Y., Counter C., Wang X-F. J. Biol. Chem. 274:1999;35381-35387.
17. Quintanilla M., Haddow S., Jonas D., Jaffe D., Bowden G. T., Balmain A. Carcinogenesis. 12:1991;1875-1881.
18. Caulín C., Scholl F. G., Frontelo P., Gamallo C., Quintanilla M. Cell Growth Differ. 6:1995;1027-1035.
19. Frontelo P., González-Garrigues M., Vilaró S., Gamallo C., Fabra A., Quintanilla M. Exp. Cell Res. 244:1998;420-432.
20. Feig L. A., Cooper G. M. Mol. Cell. Biol. 8:1988;3235-3243.
21. Sale E., Atkinson P., Sale G. EMBO J. 14:1995;674-684.
22. Kyriakis J. M., Avruch J. BioEssays. 18:1996;567-577.
23. Nanbu R., Montero L., D'Orazio D., Nagamine Y. Eur. J. Biochem. 247:1997;169-174.
24. Lengyel E., Stepp E., Gum R., Boyd D. J. Biol. Chem. 270:1995;23007-23012.
25. Taipale J., Saharinen J., Keski-Oja J. Adv. Cancer Res. 75:1998;87-134.
26. Feig L. A., Pan B-T, Roberts T. M., Cooper G. M. Proc. Natl. Acad. Sci. USA. 83:1986;4607-4611.
27. Zhang Y., Derynck R. Trends Cell Biol. 9:1999;274-279.
28. Klemke R. L., Cai S., Giannini A. L., Gallagher P. J., de Lanerolle P., Cheresh D. A. J. Cell Biol. 137:1997;481-492.
29. Montesano R., Soriano J. V., Hosseini G., Pepper M. S., Schramek H. Cell Growth Differ. 10:1999;317-332.
30. Simon C., Juarez J., Nicolson G. L., Boyd D. Cancer Res. 56:1996;5369-5374.
31. Frey R. S., Mulder K. M. Cancer Res. 57:1997;628-633.
32. Atfi A., Djelloul S., Chastre E., Davis R., Gespach C. J. Biol. Chem. 272:1997;1429-1432.
33. Adachi-Yamada T., Nakamura M., Irie K., Tooyasu Y., Sano Y., Mori E., Goto S., Ueno N., Nishida Y., Matsumoto K. Mol. Cell. Biol. 19:1999;2322-2329.
34. Montero L., Nagamine Y. Cancer Res. 59:1999;5286-5293.
35. Miralles F., Parra M., Caelles C., Nagamine Y., Félez J., Muñoz-Cánoves P. Mol. Cell. Biol. 18:1998;4537-4547.