-
1
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators
-
10.1056/NEJM199803263381301
-
Palella FJ Jr Delaney KM Moorman AC Loveless MO Fuhrer J Satten GA Aschman DJ Holmberg SD Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators N Engl J Med 1998, 338l:853-60. 10.1056/ NEJM199803263381301
-
(1998)
N Engl J Med
, vol.338 l
, pp. 853-860
-
-
Palella Jr., F.J.1
Delaney, K.M.2
Moorman, A.C.3
Loveless, M.O.4
Fuhrer, J.5
Satten, G.A.6
Aschman, D.J.7
Holmberg, S.D.8
-
2
-
-
0030923798
-
Impact of combination therapy for HIV infection on inpatient census
-
10.1056/NEJM199705223362118
-
Torres RA Barr M Impact of combination therapy for HIV infection on inpatient census N Engl J Med 1997, 336l:1531-2. 10.1056/ NEJM199705223362118
-
(1997)
N Engl J Med
, vol.336 l
, pp. 1531-1532
-
-
Torres, R.A.1
Barr, M.2
-
3
-
-
33646052566
-
Immunological recovery and antiretroviral therapy in HIV-1 infection
-
10.1016/S1473-3099(06)70463-7 16631548
-
Battegay M Nuesch R Hirschel B Kaufmann GR Immunological recovery and antiretroviral therapy in HIV-1 infection Lancet Infect Dis 2006, 6(5):280-7. 10.1016/S1473-3099(06)70463-7 16631548
-
(2006)
Lancet Infect Dis
, vol.6
, Issue.5
, pp. 280-287
-
-
Battegay, M.1
Nuesch, R.2
Hirschel, B.3
Kaufmann, G.R.4
-
4
-
-
0030952479
-
Decay characteristics of HIV-1-infected compartments during combination therapy
-
10.1038/387188a0 9144290
-
Perelson AS Essunger P Cao Y Vesanen M Hurley A Saksela K Markowitz M Ho DD Decay characteristics of HIV-1-infected compartments during combination therapy Nature 1997, 387(6629):188-91. 10.1038/387188a0 9144290
-
(1997)
Nature
, vol.387
, Issue.6629
, pp. 188-191
-
-
Perelson, A.S.1
Essunger, P.2
Cao, Y.3
Vesanen, M.4
Hurley, A.5
Saksela, K.6
Markowitz, M.7
Ho, D.D.8
-
5
-
-
15144342918
-
Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection
-
10.1126/science.276.5314.960 9139661
-
Cavert W Notermans DW Staskus K Wietgrefe SW Zupancic M Gebhard K Henry K Zhang ZQ Mills R McDade H Schuwirth CM Goudsmit J Danner SA Haase AT Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection Science 1997, 276(5314):960-4. 10.1126/ science.276.5314.960 9139661
-
(1997)
Science
, vol.276
, Issue.5314
, pp. 960-964
-
-
Cavert, W.1
Notermans, D.W.2
Staskus, K.3
Wietgrefe, S.W.4
Zupancic, M.5
Gebhard, K.6
Henry, K.7
Zhang, Z.Q.8
Mills, R.9
McDade, H.10
Schuwirth, C.M.11
Goudsmit, J.12
Danner, S.A.13
Haase, A.T.14
-
6
-
-
14444273439
-
Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
-
[see comments] 9360927 10.1126/science.278.5341.1295 9360927
-
Finzi D Hermankova M Pierson T Carruth LM Buck C Chaisson RE Quinn TC Chadwick K Margolick J Brookmeyer R Gallant J Markowitz M Ho DD Richman DD Siliciano RF Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy [see comments] Science 1997, 278(5341):1295-300. 10.1126/science.278.5341.1295 9360927
-
(1997)
Science
, vol.278
, Issue.5341
, pp. 1295-1300
-
-
Finzi, D.1
Hermankova, M.2
Pierson, T.3
Carruth, L.M.4
Buck, C.5
Chaisson, R.E.6
Quinn, T.C.7
Chadwick, K.8
Margolick, J.9
Brookmeyer, R.10
Gallant, J.11
Markowitz, M.12
Ho, D.D.13
Richman, D.D.14
Siliciano, R.F.15
-
7
-
-
0030659177
-
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
-
10.1073/pnas.94.24.13193 9371822 24285
-
Chun TW Stuyver L Mizell SB Ehler LA Mican JA Baseler M Lloyd AL Nowak MA Fauci AS Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy Proc Natl Acad Sci USA 1997, 94:13193-7. 10.1073/pnas.94.24.13193 9371822 24285
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13193-13197
-
-
Chun, T.W.1
Stuyver, L.2
Mizell, S.B.3
Ehler, L.A.4
Mican, J.A.5
Baseler, M.6
Lloyd, A.L.7
Nowak, M.A.8
Fauci, A.S.9
-
8
-
-
0030712305
-
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
-
[see comments] 10.1126/science.278.5341.1291 9360926
-
Wong JK Hezareh M Gunthard HF Havlir DV Ignacio CC Spina CA Richman DD Recovery of replication-competent HIV despite prolonged suppression of plasma viremia [see comments] Science 1997, 278:1291-5. 10.1126/ science.278.5341.1291 9360926
-
(1997)
Science
, vol.278
, pp. 1291-1295
-
-
Wong, J.K.1
Hezareh, M.2
Gunthard, H.F.3
Havlir, D.V.4
Ignacio, C.C.5
Spina, C.A.6
Richman, D.D.7
-
9
-
-
0033609374
-
Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy
-
10.1056/NEJM199905273402102 10341273
-
Furtado MR Callaway DS Phair JP Kunstman KJ Stanton JL Macken CA Perelson AS Wolinsky SM Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy N Engl J Med 1999, 340:1614-22. 10.1056/ NEJM199905273402102 10341273
-
(1999)
N Engl J Med
, vol.340
, pp. 1614-1622
-
-
Furtado, M.R.1
Callaway, D.S.2
Phair, J.P.3
Kunstman, K.J.4
Stanton, J.L.5
Macken, C.A.6
Perelson, A.S.7
Wolinsky, S.M.8
-
10
-
-
0033635471
-
HIV-1 can be recovered from a variety of cells including peripheral blood monocytes of patients receiving highly active antiretroviral therapy: A further obstacle to eradication
-
10985250
-
Crowe SM Sonza S HIV-1 can be recovered from a variety of cells including peripheral blood monocytes of patients receiving highly active antiretroviral therapy: A further obstacle to eradication J Leukoc Biol 2000, 68:345-350. 10985250
-
(2000)
J Leukoc Biol
, vol.68
, pp. 345-350
-
-
Crowe, S.M.1
Sonza, S.2
-
11
-
-
0034144463
-
Detection of infectious HIV in circulating monocytes from patients on prolonged highly active antiretroviral therapy
-
10737425
-
Lambotte O Taoufik Y de Goer MG Wallon C Goujard C Delfraissy JF Detection of infectious HIV in circulating monocytes from patients on prolonged highly active antiretroviral therapy J Acquir Immune Defic Syndr 2000, 23(2):114-9. 10737425
-
(2000)
J Acquir Immune Defic Syndr
, vol.23
, Issue.2
, pp. 114-119
-
-
Lambotte, O.1
Taoufik, Y.2
de Goer, M.G.3
Wallon, C.4
Goujard, C.5
Delfraissy, J.F.6
-
12
-
-
0033592967
-
HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression
-
10.1073/pnas.96.26.15109 10611346 24781
-
Davey RT Jr Bhat N Yoder C Chun TW Metcalf JA Dewar R Natarajan V Lempicki RA Adelsberger JW Miller KD Kovacs JA Polis MA Walker RE Falloon J Masur H Gee D Baseler M Dimitrov DS Fauci AS Lane HC HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression Proc Natl Acad Sci USA 1999, 96:15109-14. 10.1073/ pnas.96.26.15109 10611346 24781
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 15109-15114
-
-
Davey Jr., R.T.1
Bhat, N.2
Yoder, C.3
Chun, T.W.4
Metcalf, J.A.5
Dewar, R.6
Natarajan, V.7
Lempicki, R.A.8
Adelsberger, J.W.9
Miller, K.D.10
Kovacs, J.A.11
Polis, M.A.12
Walker, R.E.13
Falloon, J.14
Masur, H.15
Gee, D.16
Baseler, M.17
Dimitrov, D.S.18
Fauci, A.S.19
Lane, H.C.20
more..
-
13
-
-
0000228695
-
Pre-HAART HIV burden approximates post-HAART viral levels following interruption of therapy in patients with sustained viral suppression
-
10.1097/00002030-200007070-00008 10930150
-
Hatano H Vogel S Yoder C Metcalf JA Dewar R Davey RT Jr Polis MA Pre-HAART HIV burden approximates post-HAART viral levels following interruption of therapy in patients with sustained viral suppression Aids 2000, 14:1357-63. 10.1097/00002030-200007070-00008 10930150
-
(2000)
Aids
, vol.14
, pp. 1357-1363
-
-
Hatano, H.1
Vogel, S.2
Yoder, C.3
Metcalf, J.A.4
Dewar, R.5
Davey Jr., R.T.6
Polis, M.A.7
-
14
-
-
0032953920
-
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
-
10229227 10.1038/8394
-
Finzi D Blankson J Siliciano JD Margolick JB Chadwick K Pierson T Smith K Lisziewicz J Lori F Flexner C Quinn TC Chaisson RE Rosenberg E Walker B Gange S Gallant J Siliciano RF Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy Nat Med 1999, 5(5):512-517. 10229227 10.1038/8394
-
(1999)
Nat Med
, vol.5
, Issue.5
, pp. 512-517
-
-
Finzi, D.1
Blankson, J.2
Siliciano, J.D.3
Margolick, J.B.4
Chadwick, K.5
Pierson, T.6
Smith, K.7
Lisziewicz, J.8
Lori, F.9
Flexner, C.10
Quinn, T.C.11
Chaisson, R.E.12
Rosenberg, E.13
Walker, B.14
Gange, S.15
Gallant, J.16
Siliciano, R.F.17
-
15
-
-
0033984045
-
The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy
-
10613829 10.1038/71577
-
Ramratnam B Mittler JE Zhang L Boden D Hurley A Fang F Macken CA Perelson AS Markowitz M Ho DD The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy Nat Med 2000, 6(1):82-5. 10613829 10.1038/71577
-
(2000)
Nat Med
, vol.6
, Issue.1
, pp. 82-85
-
-
Ramratnam, B.1
Mittler, J.E.2
Zhang, L.3
Boden, D.4
Hurley, A.5
Fang, F.6
Macken, C.A.7
Perelson, A.S.8
Markowitz, M.9
Ho, D.D.10
-
16
-
-
9144265028
-
Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication
-
10.1097/00126334-200401010-00004 14707789
-
Ramratnam B Ribeiro R He T Chung C Simon V Vanderhoeven J Hurley A Zhang L Perelson AS Ho DD Markowitz M Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication J Acquir Immune Defic Syndr 2004, 35(1):33-37. 10.1097/00126334-200401010-00004 14707789
-
(2004)
J Acquir Immune Defic Syndr
, vol.35
, Issue.1
, pp. 33-37
-
-
Ramratnam, B.1
Ribeiro, R.2
He, T.3
Chung, C.4
Simon, V.5
Vanderhoeven, J.6
Hurley, A.7
Zhang, L.8
Perelson, A.S.9
Ho, D.D.10
Markowitz, M.11
-
17
-
-
0036138852
-
Evidence for human immunodeficiency virus type 1 replication in vivo in CD14(+) monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy
-
10.1128/JVI.76.2.707-716.2002 11752161 136806
-
Zhu T Muthui D Holte S Nickle D Feng F Brodie S Hwangbo Y Mullins JI Corey L Evidence for human immunodeficiency virus type 1 replication in vivo in CD14(+) monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy J Virol 2002, 76:707-716. 10.1128/JVI.76.2.707-716.2002 11752161 136806
-
(2002)
J Virol
, vol.76
, pp. 707-716
-
-
Zhu, T.1
Muthui, D.2
Holte, S.3
Nickle, D.4
Feng, F.5
Brodie, S.6
Hwangbo, Y.7
Mullins, J.I.8
Corey, L.9
-
18
-
-
0033914367
-
Relationship between pre-existing viral reservoirs and the reemergence of plasma viremia after discontinuation of highly active antiretroviral therapy
-
10.1038/77481 10888923
-
Chun TW Davey RT Jr Ostrowski M Shawn Justement J Engel D Mullins JI Fauci AS Relationship between pre-existing viral reservoirs and the reemergence of plasma viremia after discontinuation of highly active antiretroviral therapy Nat Med 2000, 6:757-761. 10.1038/77481 10888923
-
(2000)
Nat Med
, vol.6
, pp. 757-761
-
-
Chun, T.W.1
Davey Jr., R.T.2
Ostrowski, M.3
Shawn Justement, J.4
Engel, D.5
Mullins, J.I.6
Fauci, A.S.7
-
19
-
-
0037369101
-
Genetic characterization of rebounding human immunodeficiency virus type 1 in plasma during multiple interruptions of highly active antiretroviral therapy
-
10.1128/JVI.77.5.3229-3237.2003 12584346 149739
-
Dybul M Daucher M Jensen MA Hallahan CW Chun TW Belson M Hidalgo B Nickle DC Yoder C Metcalf JA Davey RT Ehler L Kress-Rock D Nies-Kraske E Liu S Mullins JI Fauci AS Genetic characterization of rebounding human immunodeficiency virus type 1 in plasma during multiple interruptions of highly active antiretroviral therapy J Virol 2003, 77:3229-3237. 10.1128/ JVI.77.5.3229-3237.2003 12584346 149739
-
(2003)
J Virol
, vol.77
, pp. 3229-3237
-
-
Dybul, M.1
Daucher, M.2
Jensen, M.A.3
Hallahan, C.W.4
Chun, T.W.5
Belson, M.6
Hidalgo, B.7
Nickle, D.C.8
Yoder, C.9
Metcalf, J.A.10
Davey, R.T.11
Ehler, L.12
Kress-Rock, D.13
Nies-Kraske, E.14
Liu, S.15
Mullins, J.I.16
Fauci, A.S.17
-
20
-
-
0347951393
-
The contribution of monocyte infection and trafficking to viral persistence, and maintenance of the viral reservoir in HIV infection
-
10.1189/jlb.0503204 12960232
-
Crowe S Zhu T Muller WA The contribution of monocyte infection and trafficking to viral persistence, and maintenance of the viral reservoir in HIV infection J Leukoc Biol 2003, 74:635-641. 10.1189/jlb.0503204 12960232
-
(2003)
J Leukoc Biol
, vol.74
, pp. 635-641
-
-
Crowe, S.1
Zhu, T.2
Muller, W.A.3
-
21
-
-
0035896735
-
Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: Implications for the neuropathogenesis of AIDS
-
10.1084/jem.193.8.905 11304551 2193403
-
Williams KC Corey S Westmoreland SV Pauley D Knight H deBakker C Alvarez X Lackner AA Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: Implications for the neuropathogenesis of AIDS J Exp Med 2001, 193:905-915. 10.1084/jem.193.8.905 11304551 2193403
-
(2001)
J Exp Med
, vol.193
, pp. 905-915
-
-
Williams, K.C.1
Corey, S.2
Westmoreland, S.V.3
Pauley, D.4
Knight, H.5
deBakker, C.6
Alvarez, X.7
Lackner, A.A.8
-
22
-
-
0035895214
-
Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans
-
10.1073/pnas.021551798 11136236 14644
-
Igarashi T Brown CR Endo Y Buckler-White A Plishka R Bischofberger N Hirsch V Martin MA Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans Proc Natl Acad Sci USA 2001, 98:658-663. 10.1073/pnas.021551798 11136236 14644
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 658-663
-
-
Igarashi, T.1
Brown, C.R.2
Endo, Y.3
Buckler-White, A.4
Plishka, R.5
Bischofberger, N.6
Hirsch, V.7
Martin, M.A.8
-
23
-
-
0024330712
-
Comparative assessment of antiretrovirals in human monocyte-macrophages and lymphoid cell lines acutely and chronically infected with the human immunodeficiency virus
-
10.1002/jmv.1890290306 2533247
-
Crowe SM McGrath MS Elbeik T Kirihara J Mills J Comparative assessment of antiretrovirals in human monocyte-macrophages and lymphoid cell lines acutely and chronically infected with the human immunodeficiency virus J Med Virol 1989, 29:176-180. 10.1002/jmv.1890290306 2533247
-
(1989)
J Med Virol
, vol.29
, pp. 176-180
-
-
Crowe, S.M.1
McGrath, M.S.2
Elbeik, T.3
Kirihara, J.4
Mills, J.5
-
24
-
-
0028022166
-
In vitro activity of inhibitors of late stages of the replication of HIV in chronically infected macrophages
-
8083612
-
Perno CF Aquaro S Rosenwirth B Balestra E Peichl P Billich A Villani N Calio R In vitro activity of inhibitors of late stages of the replication of HIV in chronically infected macrophages J Leukoc Biol 1994, 56(3):381-386. 8083612
-
(1994)
J Leukoc Biol
, vol.56
, Issue.3
, pp. 381-386
-
-
Perno, C.F.1
Aquaro, S.2
Rosenwirth, B.3
Balestra, E.4
Peichl, P.5
Billich, A.6
Villani, N.7
Calio, R.8
-
25
-
-
0035808518
-
Monocytes harbour replication-competent, non-latent HIV-1 in patients on highly active antiretroviral therapy
-
10.1097/00002030-200101050-00005 11192864
-
Sonza S Mutimer HP Oelrichs R Jardine D Harvey K Dunne A Purcell DF Birch C Crowe SM Monocytes harbour replication-competent, non-latent HIV-1 in patients on highly active antiretroviral therapy Aids 2001, 15:17-22. 10.1097/00002030-200101050-00005 11192864
-
(2001)
Aids
, vol.15
, pp. 17-22
-
-
Sonza, S.1
Mutimer, H.P.2
Oelrichs, R.3
Jardine, D.4
Harvey, K.5
Dunne, A.6
Purcell, D.F.7
Birch, C.8
Crowe, S.M.9
-
26
-
-
20644448203
-
Kinetics of productive and latent HIV infection in lymphatic tissue and peripheral blood during triple-drug combination therapy with or without additional interleukin-2
-
10682140
-
Stellbrink HJ Hufert FT Tenner-Racz K Lauer J Schneider C Albrecht H Racz P van Lunzen J Kinetics of productive and latent HIV infection in lymphatic tissue and peripheral blood during triple-drug combination therapy with or without additional interleukin-2 Antivir Ther 1998, 3(4):209-214. 10682140
-
(1998)
Antivir Ther
, vol.3
, Issue.4
, pp. 209-214
-
-
Stellbrink, H.J.1
Hufert, F.T.2
Tenner-Racz, K.3
Lauer, J.4
Schneider, C.5
Albrecht, H.6
Racz, P.7
van Lunzen, J.8
-
27
-
-
0033031218
-
Effect of interleukin-2 on the pool of latently infected, resting CD4+ T cells in HIV-1-infected patients receiving highly active antiretroviral therapy
-
[see comments] 10.1038/9498 10371503
-
Chun TW Engel D Mizell SB Hallahan CW Fischette M Park S Davey RT Jr Dybul M Kovacs JA Metcalf JA Mican JM Berrey MM Corey L Lane HC Fauci AS Effect of interleukin-2 on the pool of latently infected, resting CD4+ T cells in HIV-1-infected patients receiving highly active antiretroviral therapy [see comments] Nat Med 1999, 5:651-655. 10.1038/9498 10371503
-
(1999)
Nat Med
, vol.5
, pp. 651-655
-
-
Chun, T.W.1
Engel, D.2
Mizell, S.B.3
Hallahan, C.W.4
Fischette, M.5
Park, S.6
Davey Jr., R.T.7
Dybul, M.8
Kovacs, J.A.9
Metcalf, J.A.10
Mican, J.M.11
Berrey, M.M.12
Corey, L.13
Lane, H.C.14
Fauci, A.S.15
-
28
-
-
0035144503
-
Pilot study of a combination of highly active antiretroviral therapy and cytokines to induce HIV-1 remission
-
11176268
-
Lafeuillade A Poggi C Chadapaud S Hittinger G Chouraqui M Pisapia M Delbeke E Pilot study of a combination of highly active antiretroviral therapy and cytokines to induce HIV-1 remission J Acquir Immune Defic Syndr 2001, 26(1):44-55. 11176268
-
(2001)
J Acquir Immune Defic Syndr
, vol.26
, Issue.1
, pp. 44-55
-
-
Lafeuillade, A.1
Poggi, C.2
Chadapaud, S.3
Hittinger, G.4
Chouraqui, M.5
Pisapia, M.6
Delbeke, E.7
-
29
-
-
0036139572
-
Pilot study of the effects of intermittent interleukin-2 on human immunodeficiency virus (HIV)-specific immune responses in patients treated during recently acquired HIV infection
-
10.1086/338123 11756982
-
Dybul M Hidalgo B Chun TW Belson M Migueles SA Justement JS Herpin B Perry C Hallahan CW Davey RT Metcalf JA Connors M Fauci AS Pilot study of the effects of intermittent interleukin-2 on human immunodeficiency virus (HIV)-specific immune responses in patients treated during recently acquired HIV infection J Infect Dis 2002, 185:61-68. 10.1086/ 338123 11756982
-
(2002)
J Infect Dis
, vol.185
, pp. 61-68
-
-
Dybul, M.1
Hidalgo, B.2
Chun, T.W.3
Belson, M.4
Migueles, S.A.5
Justement, J.S.6
Herpin, B.7
Perry, C.8
Hallahan, C.W.9
Davey, R.T.10
Metcalf, J.A.11
Connors, M.12
Fauci, A.S.13
-
30
-
-
23744500093
-
Depletion of latent HIV-1 infection in vivo: A proof-of-concept study
-
10.1016/S0140-6736(05)67098-5 16099290 1894952
-
Lehrman G Hogue IB Palmer S Jennings C Spina CA Wiegand A Landay AL Coombs RW Richman DD Mellors JW Coffin JM Bosch RJ Margolis DM Depletion of latent HIV-1 infection in vivo: A proof-of-concept study Lancet 2005, 366:549-555. 10.1016/S0140-6736(05)67098-5 16099290 1894952
-
(2005)
Lancet
, vol.366
, pp. 549-555
-
-
Lehrman, G.1
Hogue, I.B.2
Palmer, S.3
Jennings, C.4
Spina, C.A.5
Wiegand, A.6
Landay, A.L.7
Coombs, R.W.8
Richman, D.D.9
Mellors, J.W.10
Coffin, J.M.11
Bosch, R.J.12
Margolis, D.M.13
-
31
-
-
33847642822
-
Stability of the latent reservoir for HIV-1 in patients receiving valproic acid
-
10.1086/511823 17299713
-
Siliciano JD Lai J Callender M Pitt E Zhang H Margolick JB Gallant JE Cofrancesco J Jr Moore RD Gange SJ Siliciano RF Stability of the latent reservoir for HIV-1 in patients receiving valproic acid J Infect Dis 2007, 195:833-836. 10.1086/511823 17299713
-
(2007)
J Infect Dis
, vol.195
, pp. 833-836
-
-
Siliciano, J.D.1
Lai, J.2
Callender, M.3
Pitt, E.4
Zhang, H.5
Margolick, J.B.6
Gallant, J.E.7
Cofrancesco Jr., J.8
Moore, R.D.9
Gange, S.J.10
Siliciano, R.F.11
-
32
-
-
0023784225
-
Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein
-
10.1038/335369a0 2843774
-
Chaudhary VK Mizukami T Fuerst TR FitzGerald DJ Moss B Pastan I Berger EA Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein Nature 1988, 335:369-372. 10.1038/335369a0 2843774
-
(1988)
Nature
, vol.335
, pp. 369-372
-
-
Chaudhary, V.K.1
Mizukami, T.2
Fuerst, T.R.3
FitzGerald, D.J.4
Moss, B.5
Pastan, I.6
Berger, E.A.7
-
33
-
-
33750721630
-
StpC-based gene therapy targeting latent reservoirs of HIV-1
-
10.1016/j.antiviral.2006.06.010 16891001
-
Turner LS Tsygankov AY Henderson EE StpC-based gene therapy targeting latent reservoirs of HIV-1 Antiviral Res 2006, 72:233-241. 10.1016/ j.antiviral.2006.06.010 16891001
-
(2006)
Antiviral Res
, vol.72
, pp. 233-241
-
-
Turner, L.S.1
Tsygankov, A.Y.2
Henderson, E.E.3
-
34
-
-
33847186235
-
Rev-dependent lentiviral expression vector
-
10.1186/1742-4690-4-12 17286866 1797186
-
Wu Y Beddall MH Marsh JW Rev-dependent lentiviral expression vector Retrovirology 2007, 4:12. 10.1186/1742-4690-4-12 17286866 1797186
-
(2007)
Retrovirology
, vol.4
, pp. 12
-
-
Wu, Y.1
Beddall, M.H.2
Marsh, J.W.3
-
35
-
-
0024518918
-
The HIV-1 rev transactivator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA
-
10.1038/338254a0 2784194
-
Malim MH Hauber J Le SY Maizel JV Cullen BR The HIV-1 rev transactivator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA Nature 1989, 338:254-257. 10.1038/338254a0 2784194
-
(1989)
Nature
, vol.338
, pp. 254-257
-
-
Malim, M.H.1
Hauber, J.2
Le, S.Y.3
Maizel, J.V.4
Cullen, B.R.5
-
36
-
-
34447259569
-
Rev-dependent indicator T cell line
-
17627502 2366165
-
Wu Y Beddall MH Marsh JW Rev-dependent indicator T cell line Current HIV Research 2007, 5(4):395-403. 17627502 2366165
-
(2007)
Current HIV Research
, vol.5
, Issue.4
, pp. 395-403
-
-
Wu, Y.1
Beddall, M.H.2
Marsh, J.W.3
-
37
-
-
0032509103
-
Self-interaction of pneumolysin, the pore-forming protein toxin of Streptococcus pneumoniae
-
10.1006/jmbi.1998.2258 9837740
-
Gilbert RJ Rossjohn J Parker MW Tweten RK Morgan PJ Mitchell TJ Errington N Rowe AJ Andrew PW Byron O Self-interaction of pneumolysin, the pore-forming protein toxin of Streptococcus pneumoniae J Mol Biol 1998, 284:1223-1237. 10.1006/jmbi.1998.2258 9837740
-
(1998)
J Mol Biol
, vol.284
, pp. 1223-1237
-
-
Gilbert, R.J.1
Rossjohn, J.2
Parker, M.W.3
Tweten, R.K.4
Morgan, P.J.5
Mitchell, T.J.6
Errington, N.7
Rowe, A.J.8
Andrew, P.W.9
Byron, O.10
-
38
-
-
0033615736
-
The mechanism of membrane insertion for a cholesteroldependent cytolysin: A novel paradigm for pore-forming toxins
-
10.1016/S0092-8674(00)81660-8 10555145
-
Shatursky O Heuck AP Shepard LA Rossjohn J Parker MW Johnson AE Tweten RK The mechanism of membrane insertion for a cholesteroldependent cytolysin: A novel paradigm for pore-forming toxins Cell 1999, 99:293-299. 10.1016/S0092-8674(00)81660-8 10555145
-
(1999)
Cell
, vol.99
, pp. 293-299
-
-
Shatursky, O.1
Heuck, A.P.2
Shepard, L.A.3
Rossjohn, J.4
Parker, M.W.5
Johnson, A.E.6
Tweten, R.K.7
-
39
-
-
0034602312
-
A PEST-like sequence in listeriolysin O essential for Listeria monocytogenes pathogenicity
-
[see comment] 10.1126/science.290.5493.992 11062133
-
Decatur AL Portnoy DA A PEST-like sequence in listeriolysin O essential for Listeria monocytogenes pathogenicity. [see comment] Science 2000, 290:992-995. 10.1126/science.290.5493.992 11062133
-
(2000)
Science
, vol.290
, pp. 992-995
-
-
Decatur, A.L.1
Portnoy, D.A.2
-
40
-
-
0042317093
-
Tumor cell killing enabled by listeriolysin O-liposome-mediated delivery of the protein toxin gelonin
-
10.1074/jbc.M305411200 12832408
-
Provoda CJ Stier EM Lee KD Tumor cell killing enabled by listeriolysin O-liposome-mediated delivery of the protein toxin gelonin J Biol Chem 2003, 278:35102-35108. 10.1074/jbc.M305411200 12832408
-
(2003)
J Biol Chem
, vol.278
, pp. 35102-35108
-
-
Provoda, C.J.1
Stier, E.M.2
Lee, K.D.3
-
41
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
10.1126/science.272.5259.263 8602510
-
Naldini L Blomer U Gallay P Ory D Mulligan R Gage FH Verma IM Trono D In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector Science 1996, 272:263-267. 10.1126/ science.272.5259.263 8602510
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
Blomer, U.2
Gallay, P.3
Ory, D.4
Mulligan, R.5
Gage, F.H.6
Verma, I.M.7
Trono, D.8
-
42
-
-
0037767296
-
Characterization of anthrolysin O, the Bacillus anthracis cholesterol-dependent cytolysin
-
10.1128/IAI.71.6.3183-3189.2003
-
Shannon JG Ross CL Koehler TM Rest RF Characterization of anthrolysin O, the Bacillus anthracis cholesterol-dependent cytolysin Infection & Immunity 2003, 71:3183-3189. 10.1128/IAI.71.6.3183-3189.2003
-
(2003)
Infection & Immunity
, vol.71
, pp. 3183-3189
-
-
Shannon, J.G.1
Ross, C.L.2
Koehler, T.M.3
Rest, R.F.4
-
43
-
-
0028853961
-
Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
-
7474080 189580
-
He J Choe S Walker R Di Marzio P Morgan DO Landau NR Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity J Virol 1995, 69(11):6705-6711. 7474080 189580
-
(1995)
J Virol
, vol.69
, Issue.11
, pp. 6705-6711
-
-
He, J.1
Choe, S.2
Walker, R.3
Di Marzio, P.4
Morgan, D.O.5
Landau, N.R.6
-
44
-
-
0028914179
-
Integration is required for productive infection of monocyte-derived macrophages by human immunodeficiency virus type 1
-
189028 7707554
-
Englund G Theodore TS Freed EO Engleman A Martin MA Integration is required for productive infection of monocyte-derived macrophages by human immunodeficiency virus type 1 J Virol 1995, 69(5):3216-3219. 189028 7707554
-
(1995)
J Virol
, vol.69
, Issue.5
, pp. 3216-3219
-
-
Englund, G.1
Theodore, T.S.2
Freed, E.O.3
Engleman, A.4
Martin, M.A.5
-
45
-
-
27244439667
-
Blocking anthrax lethal toxin at the protective antigen channel by using structure-inspired drug design
-
10.1073/pnas.0507488102 16214885 1257733
-
Karginov VA Nestorovich EM Moayeri M Leppla SH Bezrukov SM Blocking anthrax lethal toxin at the protective antigen channel by using structure-inspired drug design Proc Natl Acad Sci USA 2005, 102:15075-15080. 10.1073/pnas.0507488102 16214885 1257733
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15075-15080
-
-
Karginov, V.A.1
Nestorovich, E.M.2
Moayeri, M.3
Leppla, S.H.4
Bezrukov, S.M.5
-
47
-
-
0018167496
-
One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell
-
10.1016/0092-8674(78)90099-5 699044
-
Yamaizumi M Mekada E Uchida T Okada Y One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell Cell 1978, 15:245-250. 10.1016/0092-8674(78)90099-5 699044
-
(1978)
Cell
, vol.15
, pp. 245-250
-
-
Yamaizumi, M.1
Mekada, E.2
Uchida, T.3
Okada, Y.4
-
48
-
-
0025787798
-
Alpha-toxin of Staphylococcus aureus
-
1779933 372845
-
Bhakdi S Tranum-Jensen J Alpha-toxin of Staphylococcus aureus Microbiol Rev 1991, 55(4):733-751. 1779933 372845
-
(1991)
Microbiol Rev
, vol.55
, Issue.4
, pp. 733-751
-
-
Bhakdi, S.1
Tranum-Jensen, J.2
-
49
-
-
33747422885
-
The Bacillus anthracis cholesterol-dependent cytolysin, Anthrolysin O, kills human neutrophils, monocytes and macrophages
-
10.1186/1471-2180-6-56 16790055 1550246
-
Mosser EM Rest RF The Bacillus anthracis cholesterol-dependent cytolysin, Anthrolysin O, kills human neutrophils, monocytes and macrophages BMC Microbiol 2006, 6:56. 10.1186/1471-2180-6-56 16790055 1550246
-
(2006)
BMC Microbiol
, vol.6
, pp. 56
-
-
Mosser, E.M.1
Rest, R.F.2
-
50
-
-
0026006998
-
An HIV-1-infected T cell clone defective in IL-2 production and Ca2+ mobilization after CD3 stimulation
-
1833465
-
Perez VL Rowe T Justement JS Butera ST June CH Folks TM An HIV-1-infected T cell clone defective in IL-2 production and Ca2+ mobilization after CD3 stimulation J Immun 1991, 147(9):3145-3148. 1833465
-
(1991)
J Immun
, vol.147
, Issue.9
, pp. 3145-3148
-
-
Perez, V.L.1
Rowe, T.2
Justement, J.S.3
Butera, S.T.4
June, C.H.5
Folks, T.M.6
-
51
-
-
0031025113
-
Macrophage tropism of human immunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor
-
8995695 191226
-
Cheng-Mayer C Liu R Landau NR Stamatatos L Macrophage tropism of human immunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor J Virol 1997, 71(2):1657-1661. 8995695 191226
-
(1997)
J Virol
, vol.71
, Issue.2
, pp. 1657-1661
-
-
Cheng-Mayer, C.1
Liu, R.2
Landau, N.R.3
Stamatatos, L.4
-
52
-
-
7244255971
-
The multifactorial nature of HIV-1 latency
-
10.1016/j.molmed.2004.09.006 15519278
-
Lassen K Han Y Zhou Y Siliciano J Siliciano RF The multifactorial nature of HIV-1 latency Trends Mol Med 2004, 10:525-531. 10.1016/ j.molmed.2004.09.006 15519278
-
(2004)
Trends Mol Med
, vol.10
, pp. 525-531
-
-
Lassen, K.1
Han, Y.2
Zhou, Y.3
Siliciano, J.4
Siliciano, R.F.5
-
53
-
-
0029859406
-
Development of HIV vectors for anti-HIV gene therapy
-
10.1073/pnas.93.21.11395 8876146 38068
-
Poeschla E Corbeau P Wong-Staal F Development of HIV vectors for anti-HIV gene therapy Proc Natl Acad Sci USA 1996, 93:11395-11399. 10.1073/pnas.93.21.11395 8876146 38068
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11395-11399
-
-
Poeschla, E.1
Corbeau, P.2
Wong-Staal, F.3
-
54
-
-
0027339344
-
Rate and mechanism of nonhomologous recombination during a single cycle of retroviral replication
-
10.1126/science.8421784 8421784
-
Zhang J Temin HM Rate and mechanism of nonhomologous recombination during a single cycle of retroviral replication Science 1993, 259:234-238. 10.1126/science.8421784 8421784
-
(1993)
Science
, vol.259
, pp. 234-238
-
-
Zhang, J.1
Temin, H.M.2
-
55
-
-
0027512751
-
3' junctions of oncogene-virus sequences and the mechanisms for formation of highly oncogenic retroviruses
-
240211 8445707
-
Zhang J Temin HM 3' junctions of oncogene-virus sequences and the mechanisms for formation of highly oncogenic retroviruses J Virol 1993, 67(4):1747-1751. 240211 8445707
-
(1993)
J Virol
, vol.67
, Issue.4
, pp. 1747-1751
-
-
Zhang, J.1
Temin, H.M.2
-
56
-
-
0035259827
-
Retroviral recombination: What drives the switch?
-
10.1038/35052098 11252957
-
Negroni M Buc H Retroviral recombination: What drives the switch? Nat Rev Mol Cell Biol 2001, 2:151-155. 10.1038/35052098 11252957
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 151-155
-
-
Negroni, M.1
Buc, H.2
-
57
-
-
0018950126
-
Generation of nondefective Rous sarcoma virus by asymmetric recombination between deletion mutants
-
6253679 353678
-
Martin GS Lee WH Duesberg PH Generation of nondefective Rous sarcoma virus by asymmetric recombination between deletion mutants J Virol 1980, 36(2):591-594. 6253679 353678
-
(1980)
J Virol
, vol.36
, Issue.2
, pp. 591-594
-
-
Martin, G.S.1
Lee, W.H.2
Duesberg, P.H.3
-
58
-
-
0141632798
-
Early transcription from nonintegrated DNA in human immunodeficiency virus infection
-
10.1128/JVI.77.19.10376-10382.2003 12970422 228496
-
Wu Y Marsh JW Early transcription from nonintegrated DNA in human immunodeficiency virus infection J Virol 2003, 77:10376-10382. 10.1128/ JVI.77.19.10376-10382.2003 12970422 228496
-
(2003)
J Virol
, vol.77
, pp. 10376-10382
-
-
Wu, Y.1
Marsh, J.W.2
-
59
-
-
39449110192
-
Human macrophages support persistent transcription from unintegrated HIV-1 DNA
-
2276161 18054979 10.1016/j.virol.2007.11.007
-
Kelly J Beddall MH Yu D Iyer SR Marsh JW Wu Y Human macrophages support persistent transcription from unintegrated HIV-1 DNA Virology 2008, 372(2):300-312. 2276161 18054979 10.1016/j.virol.2007.11.007
-
(2008)
Virology
, vol.372
, Issue.2
, pp. 300-312
-
-
Kelly, J.1
Beddall, M.H.2
Yu, D.3
Iyer, S.R.4
Marsh, J.W.5
Wu, Y.6
-
60
-
-
33644822908
-
Effective gene therapy with nonintegrating lentiviral vectors
-
10.1038/nm1365 16491086
-
Yanez-Munoz RJ Balaggan KS MacNeil A Howe SJ Schmidt M Smith AJ Buch P MacLaren RE Anderson PN Barker SE Duran Y Bartholomae C von Kalle C Heckenlively JR Kinnon C Ali RR Thrasher AJ Effective gene therapy with nonintegrating lentiviral vectors Nat Med 2006, 12:348-353. 10.1038/ nm1365 16491086
-
(2006)
Nat Med
, vol.12
, pp. 348-353
-
-
Yanez-Munoz, R.J.1
Balaggan, K.S.2
MacNeil, A.3
Howe, S.J.4
Schmidt, M.5
Smith, A.J.6
Buch, P.7
MacLaren, R.E.8
Anderson, P.N.9
Barker, S.E.10
Duran, Y.11
Bartholomae, C.12
von Kalle, C.13
Heckenlively, J.R.14
Kinnon, C.15
Ali, R.R.16
Thrasher, A.J.17
-
61
-
-
1542287499
-
Unintegrated lentivirus DNA persistence and accessibility to expression in nondividing cells: Analysis with class I integrase mutants
-
10.1128/JVI.78.6.2906-2920.2004 14990709 353756
-
Saenz DT Loewen N Peretz M Whitwam T Barraza R Howell KG Holmes JM Good M Poeschla EM Unintegrated lentivirus DNA persistence and accessibility to expression in nondividing cells: Analysis with class I integrase mutants J Virol 2004, 78:2906-2920. 10.1128/JVI.78.6.2906-2920.2004 14990709 353756
-
(2004)
J Virol
, vol.78
, pp. 2906-2920
-
-
Saenz, D.T.1
Loewen, N.2
Peretz, M.3
Whitwam, T.4
Barraza, R.5
Howell, K.G.6
Holmes, J.M.7
Good, M.8
Poeschla, E.M.9
-
62
-
-
33845187432
-
Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo
-
10.1073/pnas.0606197103 17095605 1693807
-
Philippe S Sarkis C Barkats M Mammeri H Ladroue C Petit C Mallet J Serguera C Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo Proc Natl Acad Sci USA 2006, 103:17684-17689. 10.1073/pnas.0606197103 17095605 1693807
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17684-17689
-
-
Philippe, S.1
Sarkis, C.2
Barkats, M.3
Mammeri, H.4
Ladroue, C.5
Petit, C.6
Mallet, J.7
Serguera, C.8
-
63
-
-
0030664181
-
Targeting of HIV- and SIV-infected cells by CD4-chemokine receptor pseudotypes
-
10.1126/science.278.5342.1462 9367958
-
Endres MJ Jaffer S Haggarty B Turner JD Doranz BJ O'Brien PJ Kolson DL Hoxie JA Targeting of HIV- and SIV-infected cells by CD4-chemokine receptor pseudotypes Science 1997, 278:1462-1464. 10.1126/ science.278.5342.1462 9367958
-
(1997)
Science
, vol.278
, pp. 1462-1464
-
-
Endres, M.J.1
Jaffer, S.2
Haggarty, B.3
Turner, J.D.4
Doranz, B.J.5
O'Brien, P.J.6
Kolson, D.L.7
Hoxie, J.A.8
-
64
-
-
33751251058
-
Gene transfer in humans using a conditionally replicating lentiviral vector
-
10.1073/pnas.0608138103 17090675 1635018
-
Levine BL Humeau LM Boyer J MacGregor RR Rebello T Lu X Binder GK Slepushkin V Lemiale F Mascola JR Bushman FD Dropulic B June CH Gene transfer in humans using a conditionally replicating lentiviral vector Proc Natl Acad Sci USA 2006, 103:17372-17377. 10.1073/pnas.0608138103 17090675 1635018
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17372-17377
-
-
Levine, B.L.1
Humeau, L.M.2
Boyer, J.3
MacGregor, R.R.4
Rebello, T.5
Lu, X.6
Binder, G.K.7
Slepushkin, V.8
Lemiale, F.9
Mascola, J.R.10
Bushman, F.D.11
Dropulic, B.12
June, C.H.13
|