JNK MAP kinase activation is required for MTOC and granule polarization in NKG2D-mediated NK cell cytotoxicity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 8, 2008, Pages 3017-3022

  Li, Changlin ^a   Ge, Baoxue ^a,b   Nicotra, Matthew ^a   Stern, Joel N H ^a   Kopcow, Hernan D ^a   Chen, Xi ^a   Strominger, Jack L ^a  

^a HARVARD UNIVERSITY   (United States)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

D JNK 1; ERK; Paxillin; siRNA; Synapse

Indexed keywords

GRANZYME B; MITOGEN ACTIVATED PROTEIN KINASE; NATURAL KILLER CELL RECEPTOR NKG2D; PAXILLIN; SCAFFOLD PROTEIN; STRESS ACTIVATED PROTEIN KINASE; GRANZYME; IMMUNOGLOBULIN RECEPTOR; MONOCLONAL ANTIBODY; NATURAL KILLER CELL ACTIVATING RECEPTORS; SMALL INTERFERING RNA;

ARTICLE; CELL STRAIN K 562; CROSS LINKING; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MICROTUBULE ORGANIZING CENTER; NATURAL KILLER CELL; PRIORITY JOURNAL; TARGET CELL; TUMOR CELL LINE; CELL POLARITY; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CYTOTOXICITY TEST; FLOW CYTOMETRY; GENETICS; IMMUNOBLOTTING; IMMUNOLOGY; METABOLISM; SIGNAL TRANSDUCTION;

ANTIBODIES, MONOCLONAL; CELL POLARITY; CYTOTOXICITY TESTS, IMMUNOLOGIC; ENZYME ACTIVATION; FLOW CYTOMETRY; GRANZYMES; HUMANS; IMMUNOBLOTTING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KILLER CELLS, NATURAL; MICROSCOPY, CONFOCAL; MICROTUBULE-ORGANIZING CENTER; PAXILLIN; RECEPTORS, IMMUNOLOGIC; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 42949161130     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0712310105     Document Type: Article

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