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Volumn 251, Issue 1-2, 2006, Pages 103-111

Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor

Author keywords

Corticotropin releasing factor 2 receptor (CRF2R); Ghrelin; Growth hormone secretagogue receptor type 1a (GHS R1a); INS 1E; Insulin; Unacylated ghrelin

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR 2; GHRELIN; GROWTH HORMONE SECRETAGOGUE RECEPTOR; HISTIDYL DEXTRO TRYPTOPHYLALANYLTRYPTOPHYL DEXTRO PHENYLALANYLLYSINAMIDE; MESSENGER RNA;

EID: 33646582986     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2006.03.040     Document Type: Article
Times cited : (67)

References (41)
  • 1
    • 0036083399 scopus 로고    scopus 로고
    • Ghrelin stimulates insulin secretion from the pancreas of normal and diabetic rats
    • Adeghate E., and Ponery A.S. Ghrelin stimulates insulin secretion from the pancreas of normal and diabetic rats. J. Neuroendocrinol. 14 (2002) 555-560
    • (2002) J. Neuroendocrinol. , vol.14 , pp. 555-560
    • Adeghate, E.1    Ponery, A.S.2
  • 6
    • 0035039474 scopus 로고    scopus 로고
    • Unnatural growth hormone-releasing peptide begets natural ghrelin
    • Bowers C.Y. Unnatural growth hormone-releasing peptide begets natural ghrelin. J. Clin. Endocrinol. Metab. 86 (2001) 1464-1469
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 1464-1469
    • Bowers, C.Y.1
  • 10
    • 12144290080 scopus 로고    scopus 로고
    • Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines
    • Cassoni P., Ghe C., Marrocco T., Tarabra E., Allia E., Catapano F., Deghenghi R., Ghigo E., Papotti M., and Muccioli G. Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines. Eur. J. Endocrinol. 150 (2004) 173-184
    • (2004) Eur. J. Endocrinol. , vol.150 , pp. 173-184
    • Cassoni, P.1    Ghe, C.2    Marrocco, T.3    Tarabra, E.4    Allia, E.5    Catapano, F.6    Deghenghi, R.7    Ghigo, E.8    Papotti, M.9    Muccioli, G.10
  • 11
    • 17744396454 scopus 로고    scopus 로고
    • Identification, characterization, and biological activity of specific receptors for natural (ghrelin) and synthetic growth hormone secretagogues and analogs in human breast carcinomas and cell lines
    • Cassoni P., Papotti M., Ghe C., Catapano F., Sapino A., Graziani A., Deghenghi R., Reissmann T., Ghigo E., and Muccioli G. Identification, characterization, and biological activity of specific receptors for natural (ghrelin) and synthetic growth hormone secretagogues and analogs in human breast carcinomas and cell lines. J. Clin. Endocrinol. Metab. 86 (2001) 1738-1745
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 1738-1745
    • Cassoni, P.1    Papotti, M.2    Ghe, C.3    Catapano, F.4    Sapino, A.5    Graziani, A.6    Deghenghi, R.7    Reissmann, T.8    Ghigo, E.9    Muccioli, G.10
  • 12
    • 7544230057 scopus 로고    scopus 로고
    • Signal transduction mechanism of the seabream growth hormone secretagogue receptor
    • Chan C.B., Leung P.K., Wise H., and Cheng C.H. Signal transduction mechanism of the seabream growth hormone secretagogue receptor. FEBS Lett. 577 (2004) 147-153
    • (2004) FEBS Lett. , vol.577 , pp. 147-153
    • Chan, C.B.1    Leung, P.K.2    Wise, H.3    Cheng, C.H.4
  • 13
  • 14
    • 0042626304 scopus 로고    scopus 로고
    • Effects of ghrelin and other neuropeptides (CART, MCH, orexin A and B, and GLP-1) on the release of insulin from isolated rat islets
    • Colombo M., Gregersen S., Xiao J., and Hermansen K. Effects of ghrelin and other neuropeptides (CART, MCH, orexin A and B, and GLP-1) on the release of insulin from isolated rat islets. Pancreas 27 (2003) 161-166
    • (2003) Pancreas , vol.27 , pp. 161-166
    • Colombo, M.1    Gregersen, S.2    Xiao, J.3    Hermansen, K.4
  • 17
    • 32244439458 scopus 로고    scopus 로고
    • IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion
    • Doi A., Shono T., Nishi M., Furuta H., Sasaki H., and Nanjo K. IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 885-890
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 885-890
    • Doi, A.1    Shono, T.2    Nishi, M.3    Furuta, H.4    Sasaki, H.5    Nanjo, K.6
  • 18
  • 22
    • 27344437877 scopus 로고    scopus 로고
    • A novel growth hormone secretagogue-1a receptor antagonist that blocks ghrelin-induced growth hormone secretion but induces increased body weight gain
    • Halem H.A., Taylor J.E., Dong J.Z., Shen Y., Datta R., Abizaid A., Diano S., Horvath T.L., and Culler M.D. A novel growth hormone secretagogue-1a receptor antagonist that blocks ghrelin-induced growth hormone secretion but induces increased body weight gain. Neuroendocrinology 81 (2005) 339-349
    • (2005) Neuroendocrinology , vol.81 , pp. 339-349
    • Halem, H.A.1    Taylor, J.E.2    Dong, J.Z.3    Shen, Y.4    Datta, R.5    Abizaid, A.6    Diano, S.7    Horvath, T.L.8    Culler, M.D.9
  • 24
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3    Nakazato, M.4    Matsuo, H.5    Kangawa, K.6
  • 25
    • 0036141195 scopus 로고    scopus 로고
    • Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations
    • Lee H.M., Wang G., Englander E.W., Kojima M., and Greeley Jr. G.H. Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations. Endocrinology 143 (2002) 185-190
    • (2002) Endocrinology , vol.143 , pp. 185-190
    • Lee, H.M.1    Wang, G.2    Englander, E.W.3    Kojima, M.4    Greeley Jr., G.H.5
  • 27
    • 0842291578 scopus 로고    scopus 로고
    • Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells
    • Merglen A., Theander S., Rubi B., Chaffard G., Wollheim C.B., and Maechler P. Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. Endocrinology 145 (2004) 667-678
    • (2004) Endocrinology , vol.145 , pp. 667-678
    • Merglen, A.1    Theander, S.2    Rubi, B.3    Chaffard, G.4    Wollheim, C.B.5    Maechler, P.6
  • 29
    • 4444246201 scopus 로고    scopus 로고
    • Ghrelin and des-acyl ghrelin both inhibit isoproterenol-induced lipolysis in rat adipocytes via a non-type 1a growth hormone secretagogue receptor
    • Muccioli G., Pons N., Ghe C., Catapano F., Granata R., and Ghigo E. Ghrelin and des-acyl ghrelin both inhibit isoproterenol-induced lipolysis in rat adipocytes via a non-type 1a growth hormone secretagogue receptor. Eur. J. Pharmacol. 498 (2004) 27-35
    • (2004) Eur. J. Pharmacol. , vol.498 , pp. 27-35
    • Muccioli, G.1    Pons, N.2    Ghe, C.3    Catapano, F.4    Granata, R.5    Ghigo, E.6
  • 30
  • 32
    • 0037372044 scopus 로고    scopus 로고
    • Dose-dependent inhibition by ghrelin of insulin secretion in the mouse
    • Reimer M.K., Pacini G., and Ahren B. Dose-dependent inhibition by ghrelin of insulin secretion in the mouse. Endocrinology 144 (2003) 916-921
    • (2003) Endocrinology , vol.144 , pp. 916-921
    • Reimer, M.K.1    Pacini, G.2    Ahren, B.3
  • 33
    • 1542270842 scopus 로고    scopus 로고
    • Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice
    • Salehi A., Dornonville de la Cour C., Hakanson R., and Lundquist I. Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice. Regul. Pept. 118 (2004) 143-150
    • (2004) Regul. Pept. , vol.118 , pp. 143-150
    • Salehi, A.1    Dornonville de la Cour, C.2    Hakanson, R.3    Lundquist, I.4
  • 34
    • 18844404431 scopus 로고    scopus 로고
    • Development of growth hormone secretagogues
    • Smith R.G. Development of growth hormone secretagogues. Endocrinol. Rev. 26 (2005) 346-360
    • (2005) Endocrinol. Rev. , vol.26 , pp. 346-360
    • Smith, R.G.1
  • 35
    • 33646579887 scopus 로고    scopus 로고
    • Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
    • Sun Y., Wang P., Zheng H., and Smith R.G. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc. Natl. Acad. Sci. U.S.A. 18 (2004) 18
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.18 , pp. 18
    • Sun, Y.1    Wang, P.2    Zheng, H.3    Smith, R.G.4
  • 36
    • 1042275336 scopus 로고    scopus 로고
    • Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor
    • Thompson N.M., Gill D.A., Davies R., Loveridge N., Houston P.A., Robinson I.C., and Wells T. Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor. Endocrinology 145 (2004) 234-242
    • (2004) Endocrinology , vol.145 , pp. 234-242
    • Thompson, N.M.1    Gill, D.A.2    Davies, R.3    Loveridge, N.4    Houston, P.A.5    Robinson, I.C.6    Wells, T.7
  • 38
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop M., Smiley D.L., and Heiman M.L. Ghrelin induces adiposity in rodents. Nature 407 (2000) 908-913
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 39
    • 2942528459 scopus 로고    scopus 로고
    • Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
    • van der Lely A.J., Tschop M., Heiman M.L., and Ghigo E. Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endocrinol. Rev. 25 (2004) 426-457
    • (2004) Endocrinol. Rev. , vol.25 , pp. 426-457
    • van der Lely, A.J.1    Tschop, M.2    Heiman, M.L.3    Ghigo, E.4
  • 40
    • 1242318803 scopus 로고    scopus 로고
    • Ghrelin is expressed in a novel endocrine cell type in developing rat islets and inhibits insulin secretion from INS-1 (832/13) cells
    • Wierup N., Yang S., McEvilly R.J., Mulder H., and Sundler F. Ghrelin is expressed in a novel endocrine cell type in developing rat islets and inhibits insulin secretion from INS-1 (832/13) cells. J. Histochem. Cytochem. 52 (2004) 301-310
    • (2004) J. Histochem. Cytochem. , vol.52 , pp. 301-310
    • Wierup, N.1    Yang, S.2    McEvilly, R.J.3    Mulder, H.4    Sundler, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.