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Volumn 30, Issue 6, 2007, Pages 470-476

Lack of effect of the ghrelin gene-derived peptide obestatin on cardiomyocyte viability and metabolism

Author keywords

Apoptosis; Cardiomyocyte; Ghrelin; Metabolism; Obestatin

Indexed keywords

ARABINOSIDE; CYTOSINE; FATTY ACID; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 39; GHRELIN; GLUCOSE; IODINE 125; LACTATE DEHYDROGENASE; OBESTATIN; PEPTIDE HORMONE; UNCLASSIFIED DRUG;

EID: 34848890262     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03346330     Document Type: Article
Times cited : (33)

References (27)
  • 1
    • 27744600963 scopus 로고    scopus 로고
    • Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake
    • Zhang JV, Ren PG, Avsian-Kretchmer O, et al. Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science 2005, 310: 996-9.
    • (2005) Science , vol.310 , pp. 996-999
    • Zhang, J.V.1    Ren, P.G.2    Avsian-Kretchmer, O.3
  • 2
    • 27744500852 scopus 로고    scopus 로고
    • Nogueiras R, Tschöp M. Biomedicine. Separation of conjoined hormones yields appetite rivals. Science 2005, 310: 985-6.
    • Nogueiras R, Tschöp M. Biomedicine. Separation of conjoined hormones yields appetite rivals. Science 2005, 310: 985-6.
  • 3
    • 33749343484 scopus 로고    scopus 로고
    • Altered gastrointestinal and metabolic function in the GPR39-obestatin receptor-knockout mouse
    • Moechars D, Depoortere I, Moreaux B, et al. Altered gastrointestinal and metabolic function in the GPR39-obestatin receptor-knockout mouse. Gastroenterology 2006, 131: 1131-41.
    • (2006) Gastroenterology , vol.131 , pp. 1131-1141
    • Moechars, D.1    Depoortere, I.2    Moreaux, B.3
  • 4
    • 33751037202 scopus 로고    scopus 로고
    • Obestatin inhibits feeding but does not modulate GH and corticosterone secretion in the rat
    • Bresciani E, Rapetti D Dona F, et al. Obestatin inhibits feeding but does not modulate GH and corticosterone secretion in the rat. J Endocrinol Invest 2006, 29: RC16-8
    • (2006) J Endocrinol Invest , vol.29
    • Bresciani, E.1    Rapetti, D.2    Dona, F.3
  • 5
    • 33845911774 scopus 로고    scopus 로고
    • Effects of obestatin on energy balance and growth hormone secretion in rodents
    • Nogueiras R, Pfluger P, Tovar S, et al. Effects of obestatin on energy balance and growth hormone secretion in rodents. Endocrinology 2006, 148: 21-6.
    • (2006) Endocrinology , vol.148 , pp. 21-26
    • Nogueiras, R.1    Pfluger, P.2    Tovar, S.3
  • 6
    • 33751062773 scopus 로고    scopus 로고
    • Central obestatin administration does not modify either spontaneous or ghrelin-incluced food intake in rats
    • Seoane LM, Al-Massadi O, Pazos Y, Pagotto U, Casanueva FF. Central obestatin administration does not modify either spontaneous or ghrelin-incluced food intake in rats. J Endocrinol Invest 2006, 29: RC 13-5.
    • (2006) J Endocrinol Invest , vol.29 , Issue.RC , pp. 13-15
    • Seoane, L.M.1    Al-Massadi, O.2    Pazos, Y.3    Pagotto, U.4    Casanueva, F.F.5
  • 7
    • 33845883349 scopus 로고    scopus 로고
    • GPR39 signaling is stimulated by zinc ions but not by obestatin
    • Holst B, Egerod KL, Schild E, et al. GPR39 signaling is stimulated by zinc ions but not by obestatin. Endocrinology 2006, 148: 13-20.
    • (2006) Endocrinology , vol.148 , pp. 13-20
    • Holst, B.1    Egerod, K.L.2    Schild, E.3
  • 8
    • 11144225093 scopus 로고    scopus 로고
    • Common structural basis for constitutive activity of the ghrelin receptor family
    • Holst B, Holliday ND, Bach A, Elling CE, Cox HM, Schwartz TW. Common structural basis for constitutive activity of the ghrelin receptor family. J Biol Chem 2004, 279: 53806-17.
    • (2004) J Biol Chem , vol.279 , pp. 53806-53817
    • Holst, B.1    Holliday, N.D.2    Bach, A.3    Elling, C.E.4    Cox, H.M.5    Schwartz, T.W.6
  • 9
    • 2442515963 scopus 로고    scopus 로고
    • Growth hormone releasing pepticle (ghrelin) is synthesized and secreted by cardiomyocytes
    • Iglesias MJ, Piñeiro R, Blanco M, et al. Growth hormone releasing pepticle (ghrelin) is synthesized and secreted by cardiomyocytes. Cardiovasc Res 2004, 62: 481-8.
    • (2004) Cardiovasc Res , vol.62 , pp. 481-488
    • Iglesias, M.J.1    Piñeiro, R.2    Blanco, M.3
  • 10
    • 0032539911 scopus 로고    scopus 로고
    • HL-1 cells: A cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte
    • Claycomb WC, Lanson NA Jr, Stallworth BS, et al. HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc Natl Acad Sci USA 1998, 95: 2979-84.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2979-2984
    • Claycomb, W.C.1    Lanson Jr, N.A.2    Stallworth, B.S.3
  • 11
    • 24944532986 scopus 로고    scopus 로고
    • Adiponectin is synthesized and secreted by human and murine cardiomyocytes
    • Piñeiro R, Iglesias MJ, Gallego R, et al. Adiponectin is synthesized and secreted by human and murine cardiomyocytes. FEBS Lett 2005, 579: 5163-9.
    • (2005) FEBS Lett , vol.579 , pp. 5163-5169
    • Piñeiro, R.1    Iglesias, M.J.2    Gallego, R.3
  • 12
    • 0019061918 scopus 로고
    • Ligand: A versatile computerized approach for characterization of ligand binding sytems
    • Munson PJ, Rodbard D. Ligand: a versatile computerized approach for characterization of ligand binding sytems. Anal Biochem 1980, 107: 220-39.
    • (1980) Anal Biochem , vol.107 , pp. 220-239
    • Munson, P.J.1    Rodbard, D.2
  • 13
    • 0037422528 scopus 로고    scopus 로고
    • Doxazosin induces apoptosis in cardiomyocytes cultured in vitro by a mechanism that is independent of alphal-adrenergic blockade
    • Gonzaláz-Juanatey JR, Iglesias MJ, Alcaide C, Piñeiro R, Lago F. Doxazosin induces apoptosis in cardiomyocytes cultured in vitro by a mechanism that is independent of alphal-adrenergic blockade. Circulation 2003, 107: 127-31.
    • (2003) Circulation , vol.107 , pp. 127-131
    • Gonzaláz-Juanatey, J.R.1    Iglesias, M.J.2    Alcaide, C.3    Piñeiro, R.4    Lago, F.5
  • 14
    • 0025428079 scopus 로고
    • Use of lactate dehydrogenase release to assess changes in culture viability
    • Racher AJ, Looby D, Griffiths JB. Use of lactate dehydrogenase release to assess changes in culture viability. Cytotechnology 1990, 3: 301-7.
    • (1990) Cytotechnology , vol.3 , pp. 301-307
    • Racher, A.J.1    Looby, D.2    Griffiths, J.B.3
  • 15
    • 15544385058 scopus 로고    scopus 로고
    • Ghrelin: Structure and function
    • Kojima M, Kangawa K. Ghrelin: structure and function. Physiol Rev 2005, 85: 495-522.
    • (2005) Physiol Rev , vol.85 , pp. 495-522
    • Kojima, M.1    Kangawa, K.2
  • 16
    • 0242580169 scopus 로고    scopus 로고
    • Deletion of ghrelin impairs neither growth nor appetite
    • Sun Y, Ahmed S, Smith RG. Deletion of ghrelin impairs neither growth nor appetite. Mol Cell Biol 2003, 23: 7973-81.
    • (2003) Mol Cell Biol , vol.23 , pp. 7973-7981
    • Sun, Y.1    Ahmed, S.2    Smith, R.G.3
  • 17
    • 2542597708 scopus 로고    scopus 로고
    • Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference
    • Wortley KE, Anderson KD, Garcia K, et al. Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference. Proc Natl Acad Sci USA 2004, 101: 8227-32.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8227-8232
    • Wortley, K.E.1    Anderson, K.D.2    Garcia, K.3
  • 18
    • 29744441392 scopus 로고    scopus 로고
    • Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system
    • Cao JM, Ong H, Chen C. Effects of ghrelin and synthetic GH secretagogues on the cardiovascular system. Trends Endocrinol Metab 2006, 17: 13-8.
    • (2006) Trends Endocrinol Metab , vol.17 , pp. 13-18
    • Cao, J.M.1    Ong, H.2    Chen, C.3
  • 21
    • 0035908954 scopus 로고    scopus 로고
    • Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure
    • Nagaya N, Uematsu M, Kojima M, et al. Chronic administration of ghrelin improves left ventricular dysfunction and attenuates development of cardiac cachexia in rats with heart failure. Circulation 2001, 104: 1430-5.
    • (2001) Circulation , vol.104 , pp. 1430-1435
    • Nagaya, N.1    Uematsu, M.2    Kojima, M.3
  • 22
    • 0037164747 scopus 로고    scopus 로고
    • Ghrelin and desacyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/ 2 and PI3-kinase/AKT
    • Balclanzi G, Filigheddu N, Cutrupi S, et al. Ghrelin and desacyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/ 2 and PI3-kinase/AKT. J Cell Biol 2002, 159: 1029-37.
    • (2002) J Cell Biol , vol.159 , pp. 1029-1037
    • Balclanzi, G.1    Filigheddu, N.2    Cutrupi, S.3
  • 23
    • 33645420927 scopus 로고    scopus 로고
    • Differential BBB interactions of three ingestive peptides:obestatin, ghrelin, and adiponectin
    • Pan W, Tu H, Kastin AJ. Differential BBB interactions of three ingestive peptides:obestatin, ghrelin, and adiponectin. Peptides 2006, 27: 911-6.
    • (2006) Peptides , vol.27 , pp. 911-916
    • Pan, W.1    Tu, H.2    Kastin, A.J.3
  • 24
    • 0141761123 scopus 로고    scopus 로고
    • Ghrelin, a widespread hormone: Insights into molecular and cellular regulation of its expression and mechanism of action
    • Gualillo O, Lago F, Gómez-Reino JJ, Casanueva FF, Dieguez C. Ghrelin, a widespread hormone: insights into molecular and cellular regulation of its expression and mechanism of action. FEBS Lett 2003, 552: 105-9.
    • (2003) FEBS Lett , vol.552 , pp. 105-109
    • Gualillo, O.1    Lago, F.2    Gómez-Reino, J.J.3    Casanueva, F.F.4    Dieguez, C.5
  • 25
    • 33646141847 scopus 로고    scopus 로고
    • Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice
    • Sun Y, Asnicar M, Saha PK, Chan L, Smith RG. Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice. Cell Metab 2006, 3: 379-86.
    • (2006) Cell Metab , vol.3 , pp. 379-386
    • Sun, Y.1    Asnicar, M.2    Saha, P.K.3    Chan, L.4    Smith, R.G.5
  • 26
    • 33644522042 scopus 로고    scopus 로고
    • Ghrelin stimulates insulin-induced glucose uptake in adipocytes
    • Patel AD, Stanley SA, Murphy KG, et al. Ghrelin stimulates insulin-induced glucose uptake in adipocytes. Regul Pept 2006, 134: 17-22.
    • (2006) Regul Pept , vol.134 , pp. 17-22
    • Patel, A.D.1    Stanley, S.A.2    Murphy, K.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.