메뉴 건너뛰기




Volumn 17, Issue 1, 2008, Pages 59-67

Principles and applications of gene therapy in colon cancer

Author keywords

Colon cancer; Gene; Gene therapy; Oncogene; Plasmid; Vectors

Indexed keywords

5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; ACICLOVIR; ADENOVIRUS VECTOR; ALKYLATING AGENT; CALCIUM PHOSPHATE; CARCINOEMBRYONIC ANTIGEN; CD3 ANTIGEN; CYTOSINE DEAMINASE; DIETHYLAMINOETHYLDEXTRAN; DOXIFLURIDINE; DRUG METABOLITE; FLUCYTOSINE; FLUOROURACIL; GANCICLOVIR; GANCICLOVIR TRIPHOSPHATE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMAGGLUTININ VIRUS VECTOR; HERPES SIMPLEX VIRUS VECTOR; INTERLEUKIN 2; LENTI VIRUS VECTOR; NITROREDUCTASE; ONCOFETAL ANTIGEN; PLASMID DNA; POX VIRUS VECTOR; RETROVIRUS VECTOR; THYMIDINE KINASE; THYMIDINE PHOSPHORYLASE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VACCINIA VIRUS VECTOR; VIRUS VECTOR;

EID: 42449105771     PISSN: 18418724     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (19)

References (104)
  • 1
    • 0034734896 scopus 로고    scopus 로고
    • ABC of colorectal cancer: Epidemiology
    • Boyle P, Langman JS. ABC of colorectal cancer: Epidemiology. BMJ 2000; 321: 805-808.
    • (2000) BMJ , vol.321 , pp. 805-808
    • Boyle, P.1    Langman, J.S.2
  • 2
    • 0034638641 scopus 로고    scopus 로고
    • ABC of colorectal cancer: Adjuvant therapy
    • Midgley RS, Kerr DJ. ABC of colorectal cancer: adjuvant therapy. BMJ 2000; 321: 1208-1211.
    • (2000) BMJ , vol.321 , pp. 1208-1211
    • Midgley, R.S.1    Kerr, D.J.2
  • 3
    • 0032903825 scopus 로고    scopus 로고
    • Synergetic effects of retrovirus IFN-alpha gene transfer and 5-FU on apoptosis of colon cancer cells
    • Sabaawy HE, Farley T, Ahmed T, Feldman E, Abraham NG. Synergetic effects of retrovirus IFN-alpha gene transfer and 5-FU on apoptosis of colon cancer cells. Acta Haematol 1999; 101: 82-88.
    • (1999) Acta Haematol , vol.101 , pp. 82-88
    • Sabaawy, H.E.1    Farley, T.2    Ahmed, T.3    Feldman, E.4    Abraham, N.G.5
  • 5
  • 6
    • 0022103152 scopus 로고
    • Human gene therapy: Scientific and ethical considerations
    • Anderson WF. Human gene therapy: scientific and ethical considerations. J Med Philos 1985; 10: 275-291.
    • (1985) J Med Philos , vol.10 , pp. 275-291
    • Anderson, W.F.1
  • 7
    • 4444370799 scopus 로고    scopus 로고
    • Gene therapy clinical trials worldwide 1989-2004-an overview
    • Edelstein ML, Abedi MR, Wixon J, Edelstein RM. Gene therapy clinical trials worldwide 1989-2004-an overview. J Gene Med 2004; 6: 597-602.
    • (2004) J Gene Med , vol.6 , pp. 597-602
    • Edelstein, M.L.1    Abedi, M.R.2    Wixon, J.3    Edelstein, R.M.4
  • 8
    • 31144475398 scopus 로고    scopus 로고
    • Viral gene therapy strategies: From basic science to clinical application
    • Young LS, Searle PF, Onion D, Mautner V. Viral gene therapy strategies: from basic science to clinical application. J Pathol 2006; 208: 299-318.
    • (2006) J Pathol , vol.208 , pp. 299-318
    • Young, L.S.1    Searle, P.F.2    Onion, D.3    Mautner, V.4
  • 9
    • 1242289002 scopus 로고    scopus 로고
    • Systemic dissemination of viral vectors during intratumoral injection
    • Wang Y, Hu JK, Krol A, Li YP, Li CY, Yuan F. Systemic dissemination of viral vectors during intratumoral injection. Mol Cancer Ther 2003; 2: 1233-1242.
    • (2003) Mol Cancer Ther , vol.2 , pp. 1233-1242
    • Wang, Y.1    Hu, J.K.2    Krol, A.3    Li, Y.P.4    Li, C.Y.5    Yuan, F.6
  • 10
    • 33646054617 scopus 로고    scopus 로고
    • Gene therapy for immune disorders: Good news tempered by bad news
    • Puck JM, Malech HL. Gene therapy for immune disorders: good news tempered by bad news. J Allergy Clin Immunol 2006; 117: 865-869.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 865-869
    • Puck, J.M.1    Malech, H.L.2
  • 11
    • 0024988334 scopus 로고
    • Gene transfer into humans - immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction
    • Rosenberg SA, Aebersold P, Cornetta K, et al. Gene transfer into humans - immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction. N Engl J Med 1990; 323: 570-578.
    • (1990) N Engl J Med , vol.323 , pp. 570-578
    • Rosenberg, S.A.1    Aebersold, P.2    Cornetta, K.3
  • 12
    • 0025619343 scopus 로고
    • Selection of gene-marked tumor infiltrating lymphocytes from post-treatment biopsies: A case study
    • Aebersold P, Kasid A, Rosenberg SA. Selection of gene-marked tumor infiltrating lymphocytes from post-treatment biopsies: a case study. Hum Gene Ther 1990; 1: 373-384.
    • (1990) Hum Gene Ther , vol.1 , pp. 373-384
    • Aebersold, P.1    Kasid, A.2    Rosenberg, S.A.3
  • 13
    • 34347225590 scopus 로고    scopus 로고
    • Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model
    • Hiraoka K, Kimura T, Logg CR, et al. Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model. Cancer Res 2007; 67: 5345-5353.
    • (2007) Cancer Res , vol.67 , pp. 5345-5353
    • Hiraoka, K.1    Kimura, T.2    Logg, C.R.3
  • 15
    • 34347206848 scopus 로고    scopus 로고
    • Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter
    • Li HJ, Everts M, Pereboeva L, et al. Adenovirus tumor targeting and hepatic untargeting by a coxsackie/adenovirus receptor ectodomain anti-carcinoembryonic antigen bispecific adapter. Cancer Res 2007; 67: 5354-5361.
    • (2007) Cancer Res , vol.67 , pp. 5354-5361
    • Li, H.J.1    Everts, M.2    Pereboeva, L.3
  • 16
    • 19744375006 scopus 로고    scopus 로고
    • Enhanced efficacy of conditionally replicating herpes simplex virus (G207) combined with 5-fluorouracil and surgical resection in peritoneal cancer dissemination models
    • Nakano K, Todo T, Zhao G, et al. Enhanced efficacy of conditionally replicating herpes simplex virus (G207) combined with 5-fluorouracil and surgical resection in peritoneal cancer dissemination models. J Gene Med 2005; 7: 638-648.
    • (2005) J Gene Med , vol.7 , pp. 638-648
    • Nakano, K.1    Todo, T.2    Zhao, G.3
  • 17
    • 27944498250 scopus 로고    scopus 로고
    • Calcium phosphate nanoparticles: Second-generation nonviral vectors in gene therapy
    • Maitra A. Calcium phosphate nanoparticles: second-generation nonviral vectors in gene therapy. Expert Rev Mol Diagn 2005; 5: 893-905.
    • (2005) Expert Rev Mol Diagn , vol.5 , pp. 893-905
    • Maitra, A.1
  • 18
    • 33749827108 scopus 로고    scopus 로고
    • Electrically-assisted nucleic acids delivery to tissues in vivo: Where do we stand?
    • Cemazar M, Golzio M, Sersa G, Rols MP, Teissie J. Electrically-assisted nucleic acids delivery to tissues in vivo: where do we stand? Curr Pharm Des 2006; 12: 3817-3825.
    • (2006) Curr Pharm Des , vol.12 , pp. 3817-3825
    • Cemazar, M.1    Golzio, M.2    Sersa, G.3    Rols, M.P.4    Teissie, J.5
  • 19
    • 34250189716 scopus 로고    scopus 로고
    • Cationic liposomes as non-viral carriers of gene medicines: Resolved issues, open questions, and future promises
    • Karmali PP, Chaudhuri A. Cationic liposomes as non-viral carriers of gene medicines: resolved issues, open questions, and future promises. Med Res Rev 2007; 27: 696-722.
    • (2007) Med Res Rev , vol.27 , pp. 696-722
    • Karmali, P.P.1    Chaudhuri, A.2
  • 20
    • 0033972869 scopus 로고    scopus 로고
    • Nonviral gene therapy: Promises and challenges
    • Li S, Huang L. Nonviral gene therapy: promises and challenges. Gene Ther 2000; 7: 31-34.
    • (2000) Gene Ther , vol.7 , pp. 31-34
    • Li, S.1    Huang, L.2
  • 21
    • 21644490243 scopus 로고    scopus 로고
    • Low-volume jet injection for efficient nonviral in vivo gene transfer
    • Walther W, Stein U, Fichtner I, Schlag PM. Low-volume jet injection for efficient nonviral in vivo gene transfer. Mol Biotechnol 2004; 28: 121-128.
    • (2004) Mol Biotechnol , vol.28 , pp. 121-128
    • Walther, W.1    Stein, U.2    Fichtner, I.3    Schlag, P.M.4
  • 22
    • 0032805251 scopus 로고    scopus 로고
    • Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
    • Liu F, Song Y, Liu D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther 1999; 6: 1258-1266.
    • (1999) Gene Ther , vol.6 , pp. 1258-1266
    • Liu, F.1    Song, Y.2    Liu, D.3
  • 24
    • 0026648941 scopus 로고
    • Genetic alterations in the adenoma-carcinoma sequence
    • Cho KR, Vogelstein B. Genetic alterations in the adenoma-carcinoma sequence. Cancer 1992; 70: 1727-1731.
    • (1992) Cancer , vol.70 , pp. 1727-1731
    • Cho, K.R.1    Vogelstein, B.2
  • 26
    • 0028806561 scopus 로고
    • Molecular biology of colon polyps and colon cancer
    • Allen JI. Molecular biology of colon polyps and colon cancer. Semin Surg Oncol 1995; 11: 399-405.
    • (1995) Semin Surg Oncol , vol.11 , pp. 399-405
    • Allen, J.I.1
  • 27
    • 0030766677 scopus 로고    scopus 로고
    • Recent advances in molecular genetics of colorectal cancer
    • Baba S. Recent advances in molecular genetics of colorectal cancer. World J Surg 1997; 21: 678-687.
    • (1997) World J Surg , vol.21 , pp. 678-687
    • Baba, S.1
  • 28
    • 34547181906 scopus 로고    scopus 로고
    • Nine novel pathogenic germline mutations in MLH1, MSH2, MSH6 and PMS2 in families with Lynch syndrome
    • Rahner N, Friedrichs N, Wehner M, et al. Nine novel pathogenic germline mutations in MLH1, MSH2, MSH6 and PMS2 in families with Lynch syndrome. Acta Oncol 2007; 46: 763-769.
    • (2007) Acta Oncol , vol.46 , pp. 763-769
    • Rahner, N.1    Friedrichs, N.2    Wehner, M.3
  • 29
    • 33751265848 scopus 로고    scopus 로고
    • DNA mismatch repair and Lynch syndrome
    • Plotz G, Zeuzem S, Raedle J. DNA mismatch repair and Lynch syndrome. J Mol Histol 2006; 37: 271-283.
    • (2006) J Mol Histol , vol.37 , pp. 271-283
    • Plotz, G.1    Zeuzem, S.2    Raedle, J.3
  • 30
    • 33847382860 scopus 로고    scopus 로고
    • Hereditary colorectal cancer syndromes: An overview
    • Kwak EL, Chung DC. Hereditary colorectal cancer syndromes: an overview. Clin Colorectal Cancer 2007; 6: 340-344.
    • (2007) Clin Colorectal Cancer , vol.6 , pp. 340-344
    • Kwak, E.L.1    Chung, D.C.2
  • 32
    • 0035345559 scopus 로고    scopus 로고
    • Future scope for gene therapy for liver metastasis of colon cancer
    • Yamamoto H, Sekimoto M, Monden M. Future scope for gene therapy for liver metastasis of colon cancer. Nippon Geka Gakkai Zasshi 2001; 102: 412-416.
    • (2001) Nippon Geka Gakkai Zasshi , vol.102 , pp. 412-416
    • Yamamoto, H.1    Sekimoto, M.2    Monden, M.3
  • 33
    • 26944450125 scopus 로고    scopus 로고
    • Experimental studies on the treatment of colon cancer by cytosine deaminase gene and 5-fluorocytosine
    • Huang JH, Wang Y, Li CH, Zhong DG, Lu HY. Experimental studies on the treatment of colon cancer by cytosine deaminase gene and 5-fluorocytosine. Zhonghua Zhong Liu Za Zhi 2005;27: 6-8.
    • (2005) Zhonghua Zhong Liu Za Zhi , vol.27 , pp. 6-8
    • Huang, J.H.1    Wang, Y.2    Li, C.H.3    Zhong, D.G.4    Lu, H.Y.5
  • 35
    • 0008407493 scopus 로고    scopus 로고
    • Tumor suppressor gene therapy for cancer: From the bench to the clinic
    • Meng RD, El Deiry WS. Tumor suppressor gene therapy for cancer: from the bench to the clinic. Drug Resist Updat 1998; 1: 205-210.
    • (1998) Drug Resist Updat , vol.1 , pp. 205-210
    • Meng, R.D.1    El Deiry, W.S.2
  • 36
    • 28444468416 scopus 로고    scopus 로고
    • Nonviral jet-injection gene transfer for efficient in vivo cytosine deaminase suicide gene therapy of colon carcinoma
    • Walther W, Stein U, Fichtner I, et al. Nonviral jet-injection gene transfer for efficient in vivo cytosine deaminase suicide gene therapy of colon carcinoma. Mol Ther 2005; 12: 1176-1184.
    • (2005) Mol Ther , vol.12 , pp. 1176-1184
    • Walther, W.1    Stein, U.2    Fichtner, I.3
  • 37
    • 8244225186 scopus 로고    scopus 로고
    • Gene therapy for colon cancer with the herpes simplex thymidine kinase gene
    • Link CJ Jr., Levy JP, McCann LZ, Moorman DW. Gene therapy for colon cancer with the herpes simplex thymidine kinase gene. J Surg Oncol 1997; 64: 289-294.
    • (1997) J Surg Oncol , vol.64 , pp. 289-294
    • Link Jr., C.J.1    Levy, J.P.2    McCann, L.Z.3    Moorman, D.W.4
  • 38
    • 0034078760 scopus 로고    scopus 로고
    • Enzyme/prodrug gene therapy for human colon cancer cells using adenovirus-mediated transfer of the Escherichia coli cytosine deaminase gene driven by a CAG promoter associated with 5-fluorocytosine administration
    • Koyama F, Sawada H, Fujii H, et al. Enzyme/prodrug gene therapy for human colon cancer cells using adenovirus-mediated transfer of the Escherichia coli cytosine deaminase gene driven by a CAG promoter associated with 5-fluorocytosine administration. J Exp Clin Cancer Res 2000; 19: 75-80.
    • (2000) J Exp Clin Cancer Res , vol.19 , pp. 75-80
    • Koyama, F.1    Sawada, H.2    Fujii, H.3
  • 39
    • 0033859488 scopus 로고    scopus 로고
    • Vaccination by suicide gene therapy against a model of hepatic metastasis from colon cancer in the rat
    • Gavelli A, Baque P, Mala M, et al. Vaccination by suicide gene therapy against a model of hepatic metastasis from colon cancer in the rat. Ann Chir 2000; 125: 552-559.
    • (2000) Ann Chir , vol.125 , pp. 552-559
    • Gavelli, A.1    Baque, P.2    Mala, M.3
  • 40
    • 0032951865 scopus 로고    scopus 로고
    • Enhancement of the antitumor effect of 5′-deoxy-5-fluorouridine by transfection of thymidine phosphorylase gene into human colon cancer cells
    • Kanyama H, Tomita N, Yamano T, et al. Enhancement of the antitumor effect of 5′-deoxy-5-fluorouridine by transfection of thymidine phosphorylase gene into human colon cancer cells. Jpn J Cancer Res 1999; 90: 454-459.
    • (1999) Jpn J Cancer Res , vol.90 , pp. 454-459
    • Kanyama, H.1    Tomita, N.2    Yamano, T.3
  • 41
    • 0034814342 scopus 로고    scopus 로고
    • Virus-directed, enzyme prodrug therapy with nitroimidazole reductase: A phase I and pharmacokinetic study of its prodrug, CB1954
    • Chung-Faye G, Palmer D, Anderson D, et al. Virus-directed, enzyme prodrug therapy with nitroimidazole reductase: a phase I and pharmacokinetic study of its prodrug, CB1954. Clin Cancer Res 2001; 7: 2662-2668.
    • (2001) Clin Cancer Res , vol.7 , pp. 2662-2668
    • Chung-Faye, G.1    Palmer, D.2    Anderson, D.3
  • 43
    • 10444280991 scopus 로고    scopus 로고
    • Herpes simplex virus thymidine kinase gene transduction enhances tumor growth rate and cyclooxygenase-2 expression in murine colon cancer cells
    • Konson A, Ben-Kasus T, Mahajna JA, Danon A, Rimon G, Agbaria R. Herpes simplex virus thymidine kinase gene transduction enhances tumor growth rate and cyclooxygenase-2 expression in murine colon cancer cells. Cancer Gene Ther 2004; 11: 830-840.
    • (2004) Cancer Gene Ther , vol.11 , pp. 830-840
    • Konson, A.1    Ben-Kasus, T.2    Mahajna, J.A.3    Danon, A.4    Rimon, G.5    Agbaria, R.6
  • 44
    • 33645027064 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 gene delivery enhances antitumor effects of herpes simplex virus thymidine kinase/ganciclovir system in a model of colon cancer
    • Kagaya T, Nakamoto Y, Sakai Y, et al. Monocyte chemoattractant protein-1 gene delivery enhances antitumor effects of herpes simplex virus thymidine kinase/ganciclovir system in a model of colon cancer. Cancer Gene Ther 2006; 13: 357-366.
    • (2006) Cancer Gene Ther , vol.13 , pp. 357-366
    • Kagaya, T.1    Nakamoto, Y.2    Sakai, Y.3
  • 45
    • 0033914616 scopus 로고    scopus 로고
    • Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of escherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine
    • Koyama F, Sawada H, Hirao T, Fujii H, Hamada H, Nakano H. Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of escherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine. Cancer Gene Ther 2000; 7: 1015-1022.
    • (2000) Cancer Gene Ther , vol.7 , pp. 1015-1022
    • Koyama, F.1    Sawada, H.2    Hirao, T.3    Fujii, H.4    Hamada, H.5    Nakano, H.6
  • 46
    • 0031262574 scopus 로고    scopus 로고
    • Inhibition of establishment of hepatic metastasis in mice by combination gene therapy using both herpes simplex virus-thymidine kinase and granulocyte macrophage-colony stimulating factor genes in murine colon cancer
    • Hayashi S, Emi N, Yokoyama I, Namii Y, Uchida K, Takagi H. Inhibition of establishment of hepatic metastasis in mice by combination gene therapy using both herpes simplex virus-thymidine kinase and granulocyte macrophage-colony stimulating factor genes in murine colon cancer. Cancer Gene Ther 1997; 4: 339-344.
    • (1997) Cancer Gene Ther , vol.4 , pp. 339-344
    • Hayashi, S.1    Emi, N.2    Yokoyama, I.3    Namii, Y.4    Uchida, K.5    Takagi, H.6
  • 47
    • 0036290399 scopus 로고    scopus 로고
    • The potential of 5-fluorocytosine/ cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model
    • Nyati MK, Symon Z, Kievit E, et al. The potential of 5-fluorocytosine/ cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model. Gene Ther 2002; 9: 844-849.
    • (2002) Gene Ther , vol.9 , pp. 844-849
    • Nyati, M.K.1    Symon, Z.2    Kievit, E.3
  • 48
    • 33747026634 scopus 로고    scopus 로고
    • Current gene therapy strategies for colorectal cancer
    • Hargest R. Current gene therapy strategies for colorectal cancer. Cancer Genomics 2000; 1: 103-115.
    • (2000) Cancer Genomics , vol.1 , pp. 103-115
    • Hargest, R.1
  • 49
    • 33645229337 scopus 로고    scopus 로고
    • Sequencing of the tumor suppressor gene TP 53
    • Linderholm B, Norberg T, Bergh J. Sequencing of the tumor suppressor gene TP 53. Methods Mol Med 2006; 120: 389-401.
    • (2006) Methods Mol Med , vol.120 , pp. 389-401
    • Linderholm, B.1    Norberg, T.2    Bergh, J.3
  • 50
    • 0036272911 scopus 로고    scopus 로고
    • P53 gene mutations: Case study of a clinical marker for solid tumors
    • Liu MC, Gelmann EP. P53 gene mutations: case study of a clinical marker for solid tumors. Semin Oncol 2002; 29: 246-257.
    • (2002) Semin Oncol , vol.29 , pp. 246-257
    • Liu, M.C.1    Gelmann, E.P.2
  • 51
    • 0034598109 scopus 로고    scopus 로고
    • ABC of colorectal cancer: Innovative treatment for colon cancer
    • Chung-Faye GA, Kerr DJ. ABC of colorectal cancer: Innovative treatment for colon cancer. BMJ 2000; 321: 1397-1399.
    • (2000) BMJ , vol.321 , pp. 1397-1399
    • Chung-Faye, G.A.1    Kerr, D.J.2
  • 52
    • 0029802591 scopus 로고    scopus 로고
    • p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
    • Chen X, Ko LJ, Jayaraman L, Prives C. p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev 1996; 10: 2438-2451.
    • (1996) Genes Dev , vol.10 , pp. 2438-2451
    • Chen, X.1    Ko, L.J.2    Jayaraman, L.3    Prives, C.4
  • 53
    • 33644527626 scopus 로고    scopus 로고
    • Gene targeting approach to selectively kill colon cancer cells, with hyperactive K-Ras pathway
    • Dvory-Sobol H, Kazanov D, Arber N. Gene targeting approach to selectively kill colon cancer cells, with hyperactive K-Ras pathway. Biomed Pharmacother 2005; 59 Suppl 2: S370-S374.
    • (2005) Biomed Pharmacother , vol.59 , Issue.SUPPL. 2
    • Dvory-Sobol, H.1    Kazanov, D.2    Arber, N.3
  • 54
    • 33746355981 scopus 로고    scopus 로고
    • Frequent involvement of ras-signalling pathways in both polypoid-type and flat-type early-stage colorectal cancers
    • Noda H, Kato Y, Yoshikawa H, et al. Frequent involvement of ras-signalling pathways in both polypoid-type and flat-type early-stage colorectal cancers. J Exp Clin Cancer Res 2006; 25: 235-242.
    • (2006) J Exp Clin Cancer Res , vol.25 , pp. 235-242
    • Noda, H.1    Kato, Y.2    Yoshikawa, H.3
  • 55
    • 0034025130 scopus 로고    scopus 로고
    • Protein expression of p53, p21 (WAF1/CIP1), bcl-2, Bax, cyclin D1 and pRb in human colon carcinomas
    • Bukholm IK, Nesland JM. Protein expression of p53, p21 (WAF1/CIP1), bcl-2, Bax, cyclin D1 and pRb in human colon carcinomas. Virchows Arch 2000; 436: 224-228.
    • (2000) Virchows Arch , vol.436 , pp. 224-228
    • Bukholm, I.K.1    Nesland, J.M.2
  • 56
    • 0026537986 scopus 로고
    • Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors
    • Sidransky D, Tokino T, Hamilton SR, et al. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 1992; 256: 102-105.
    • (1992) Science , vol.256 , pp. 102-105
    • Sidransky, D.1    Tokino, T.2    Hamilton, S.R.3
  • 57
    • 0028910558 scopus 로고
    • Inhibition of bcl-2 with antisense oligonucleotides induces apoptosis and increases the sensitivity of AML blasts to Ara-C
    • Keith FJ, Bradbury DA, Zhu YM, Russell NH. Inhibition of bcl-2 with antisense oligonucleotides induces apoptosis and increases the sensitivity of AML blasts to Ara-C. Leukemia 1995; 9: 131-138.
    • (1995) Leukemia , vol.9 , pp. 131-138
    • Keith, F.J.1    Bradbury, D.A.2    Zhu, Y.M.3    Russell, N.H.4
  • 58
    • 16544381618 scopus 로고    scopus 로고
    • Suppression of pancreatic and colon cancer cells by antisense K-ras RNA expression vectors
    • Aoki K, Ohnami S, Yoshida T. Suppression of pancreatic and colon cancer cells by antisense K-ras RNA expression vectors. Methods Mol Med 2005; 106: 193-204.
    • (2005) Methods Mol Med , vol.106 , pp. 193-204
    • Aoki, K.1    Ohnami, S.2    Yoshida, T.3
  • 59
    • 8244224532 scopus 로고    scopus 로고
    • Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7
    • Rubin J, Galanis E, Pitot HC, et al. Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7. Gene Ther 1997; 4: 419-425.
    • (1997) Gene Ther , vol.4 , pp. 419-425
    • Rubin, J.1    Galanis, E.2    Pitot, H.C.3
  • 60
    • 0041857805 scopus 로고    scopus 로고
    • Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA
    • Morse MA, Nair SK, Mosca PJ, et al. Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA. Cancer Invest 2003; 21: 341-349.
    • (2003) Cancer Invest , vol.21 , pp. 341-349
    • Morse, M.A.1    Nair, S.K.2    Mosca, P.J.3
  • 61
    • 10444241232 scopus 로고    scopus 로고
    • Adjuvant interleukin-12 gene therapy for the management of colorectal liver metastases
    • Alves A, Vibert E, Trajcevski S, et al. Adjuvant interleukin-12 gene therapy for the management of colorectal liver metastases. Cancer Gene Ther 2004; 11: 782-789.
    • (2004) Cancer Gene Ther , vol.11 , pp. 782-789
    • Alves, A.1    Vibert, E.2    Trajcevski, S.3
  • 62
    • 0033218662 scopus 로고    scopus 로고
    • Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12
    • Mazzolini G, Qian C, Xie X, et al. Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12. Cancer Gene Ther 1999; 6: 514-522.
    • (1999) Cancer Gene Ther , vol.6 , pp. 514-522
    • Mazzolini, G.1    Qian, C.2    Xie, X.3
  • 63
    • 0029859405 scopus 로고    scopus 로고
    • Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma
    • Caruso M, Pham-Nguyen K, Kwong YL, et al. Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma. Proc Natl Acad Sci U S A 1996; 93: 11302-11306.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11302-11306
    • Caruso, M.1    Pham-Nguyen, K.2    Kwong, Y.L.3
  • 64
    • 0033804952 scopus 로고    scopus 로고
    • In vivo gene transfer of CD40 ligand into colon cancer cells induces local production of cytokines and chemokines, tumor eradication and protective antitumor immunity
    • Sun Y, Peng D, Lecanda J, et al. In vivo gene transfer of CD40 ligand into colon cancer cells induces local production of cytokines and chemokines, tumor eradication and protective antitumor immunity. Gene Ther 2000; 7: 1467-1476.
    • (2000) Gene Ther , vol.7 , pp. 1467-1476
    • Sun, Y.1    Peng, D.2    Lecanda, J.3
  • 65
    • 0034547911 scopus 로고    scopus 로고
    • Mice vaccination with interleukin 12-transduced colon cancer cells potentiates rejection of syngeneic non-organ-related tumor cells
    • Adris S, Chuluyan E, Bravo A, et al. Mice vaccination with interleukin 12-transduced colon cancer cells potentiates rejection of syngeneic non-organ-related tumor cells. Cancer Res 2000; 60: 6696-6703.
    • (2000) Cancer Res , vol.60 , pp. 6696-6703
    • Adris, S.1    Chuluyan, E.2    Bravo, A.3
  • 66
    • 0022923890 scopus 로고
    • The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein
    • Ueda K, Cornwell MM, Gottesman MM, et al. The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein. Biochem Biophys Res Commun 1986; 141: 956-962.
    • (1986) Biochem Biophys Res Commun , vol.141 , pp. 956-962
    • Ueda, K.1    Cornwell, M.M.2    Gottesman, M.M.3
  • 67
    • 34447644973 scopus 로고    scopus 로고
    • Eradication of hepatoma and colon cancer in mice with Flt3L gene therapy in combination with 5-FU
    • Hou S, Kou G, Fan X, Wang H, et al. Eradication of hepatoma and colon cancer in mice with Flt3L gene therapy in combination with 5-FU. Cancer Immunol Immunother 2007; 56: 1605-1613.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 1605-1613
    • Hou, S.1    Kou, G.2    Fan, X.3    Wang, H.4
  • 68
    • 0029962567 scopus 로고    scopus 로고
    • Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells
    • Yang B, Eshleman JR, Berger NA, Markowitz SD. Wild-type p53 protein potentiates cytotoxicity of therapeutic agents in human colon cancer cells. Clin Cancer Res 1996; 2: 1649-1657.
    • (1996) Clin Cancer Res , vol.2 , pp. 1649-1657
    • Yang, B.1    Eshleman, J.R.2    Berger, N.A.3    Markowitz, S.D.4
  • 69
    • 0030781397 scopus 로고    scopus 로고
    • Novel combination therapy for human colon cancer with adenovirus-mediated wild-type p53 gene transfer and DNA-damaging chemotherapeutic agent
    • Ogawa N, Fujiwara T, Kagawa S, et al. Novel combination therapy for human colon cancer with adenovirus-mediated wild-type p53 gene transfer and DNA-damaging chemotherapeutic agent. Int J Cancer 1997; 73: 367-370.
    • (1997) Int J Cancer , vol.73 , pp. 367-370
    • Ogawa, N.1    Fujiwara, T.2    Kagawa, S.3
  • 70
    • 0033146438 scopus 로고    scopus 로고
    • Enhancement of 5-fluorouracil cytotoxicity on human colon cancer cells by retrovirus-mediated interferon-alpha gene transfer
    • Sabaawy HM, Ikehara S, Adachi Y, et al. Enhancement of 5-fluorouracil cytotoxicity on human colon cancer cells by retrovirus-mediated interferon-alpha gene transfer. Int J Oncol 1999; 14: 1143-1151.
    • (1999) Int J Oncol , vol.14 , pp. 1143-1151
    • Sabaawy, H.M.1    Ikehara, S.2    Adachi, Y.3
  • 71
    • 0032747138 scopus 로고    scopus 로고
    • Enzyme prodrug gene therapy: Synergistic use of the herpes simplex virus-cellular thymidine kinase/ganciclovir system and thymidylate synthase inhibitors for the treatment of colon cancer
    • Wildner O, Blaese RM, Candotti F. Enzyme prodrug gene therapy: synergistic use of the herpes simplex virus-cellular thymidine kinase/ganciclovir system and thymidylate synthase inhibitors for the treatment of colon cancer. Cancer Res 1999; 59: 5233-5238.
    • (1999) Cancer Res , vol.59 , pp. 5233-5238
    • Wildner, O.1    Blaese, R.M.2    Candotti, F.3
  • 72
    • 33845665266 scopus 로고    scopus 로고
    • Soluble TRAIL gene and actinomycin D synergistically suppressed multiple metastasis of TRAIL-resistant colon cancer in the liver
    • Ishii M, Iwai M, Harada Y, et al. Soluble TRAIL gene and actinomycin D synergistically suppressed multiple metastasis of TRAIL-resistant colon cancer in the liver. Cancer Lett 2007; 245: 134-143.
    • (2007) Cancer Lett , vol.245 , pp. 134-143
    • Ishii, M.1    Iwai, M.2    Harada, Y.3
  • 73
    • 0036787432 scopus 로고    scopus 로고
    • Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines
    • Adachi Y, Lee CT, Coffee K, et al. Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines. Gastroenterology 2002; 123: 1191-1204.
    • (2002) Gastroenterology , vol.123 , pp. 1191-1204
    • Adachi, Y.1    Lee, C.T.2    Coffee, K.3
  • 74
    • 0642275635 scopus 로고    scopus 로고
    • 5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells
    • Uchida H, Shinoura N, Kitayama J, Watanabe T, Nagawa H, Hamada H. 5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells. J Gene Med 2003; 5: 287-299.
    • (2003) J Gene Med , vol.5 , pp. 287-299
    • Uchida, H.1    Shinoura, N.2    Kitayama, J.3    Watanabe, T.4    Nagawa, H.5    Hamada, H.6
  • 75
    • 0034522910 scopus 로고    scopus 로고
    • Bax induction activates apoptotic cascade via mitochondrial cytochrome c release and Bax overexpression enhances apoptosis induced by chemotherapeutic agents in DLD-1 colon cancer cells
    • Kobayashi T, Sawa H, Morikawa J, Zhang W, Shiku H. Bax induction activates apoptotic cascade via mitochondrial cytochrome c release and Bax overexpression enhances apoptosis induced by chemotherapeutic agents in DLD-1 colon cancer cells. Jpn J Cancer Res 2000; 91: 1264-1268.
    • (2000) Jpn J Cancer Res , vol.91 , pp. 1264-1268
    • Kobayashi, T.1    Sawa, H.2    Morikawa, J.3    Zhang, W.4    Shiku, H.5
  • 77
    • 0041698452 scopus 로고    scopus 로고
    • Ionizing radiation increases adenovirus uptake and improves transgene expression in intrahepatic colon cancer xenografts
    • Zhang M, Li S, Li J, Ensminger WD, Lawrence TS. Ionizing radiation increases adenovirus uptake and improves transgene expression in intrahepatic colon cancer xenografts. Mol Ther 2003;8: 21-28.
    • (2003) Mol Ther , vol.8 , pp. 21-28
    • Zhang, M.1    Li, S.2    Li, J.3    Ensminger, W.D.4    Lawrence, T.S.5
  • 78
    • 33947194274 scopus 로고    scopus 로고
    • Replication-deficient adenovirus induces host topoisomerase I activity: Implications for adenovirus-mediated gene expression
    • Zamir G, Zeira E, Gelman AE, et al. Replication-deficient adenovirus induces host topoisomerase I activity: implications for adenovirus-mediated gene expression. Mol Ther 2007; 15: 772-781.
    • (2007) Mol Ther , vol.15 , pp. 772-781
    • Zamir, G.1    Zeira, E.2    Gelman, A.E.3
  • 79
    • 0037530343 scopus 로고    scopus 로고
    • Continuous release of interleukin 12 from microencapsulated engineered cells for colon cancer therapy
    • Zheng S, Xiao ZX, Pan YL, Han MY, Dong Q. Continuous release of interleukin 12 from microencapsulated engineered cells for colon cancer therapy. World J Gastroenterol 2003; 9: 951-955.
    • (2003) World J Gastroenterol , vol.9 , pp. 951-955
    • Zheng, S.1    Xiao, Z.X.2    Pan, Y.L.3    Han, M.Y.4    Dong, Q.5
  • 80
    • 0035177690 scopus 로고    scopus 로고
    • Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: A phase I trial
    • Reid T, Galanis E, Abbruzzese J, et al. Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial. Gene Ther 2001; 8: 1618-1626.
    • (2001) Gene Ther , vol.8 , pp. 1618-1626
    • Reid, T.1    Galanis, E.2    Abbruzzese, J.3
  • 81
    • 0033556003 scopus 로고    scopus 로고
    • Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase
    • Wildner O, Blaese RM, Morris JC. Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase. Cancer Res 1999; 59: 410-413.
    • (1999) Cancer Res , vol.59 , pp. 410-413
    • Wildner, O.1    Blaese, R.M.2    Morris, J.C.3
  • 82
    • 0033119291 scopus 로고    scopus 로고
    • Superiority of yeast over bacterial cytosine deaminase for enzyme/prodrug gene therapy in colon cancer xenografts
    • Kievit E, Bershad E, Ng E, et al. Superiority of yeast over bacterial cytosine deaminase for enzyme/prodrug gene therapy in colon cancer xenografts. Cancer Res 1999; 59: 1417-1421.
    • (1999) Cancer Res , vol.59 , pp. 1417-1421
    • Kievit, E.1    Bershad, E.2    Ng, E.3
  • 83
    • 34548083069 scopus 로고    scopus 로고
    • Adenovirus-mediated small hairpin RNA targeting Bcl-XL as therapy for colon cancer
    • Zhu H, Zhu Y, Hu J, et al. Adenovirus-mediated small hairpin RNA targeting Bcl-XL as therapy for colon cancer. Int J Cancer 2007; 121: 1366-1372.
    • (2007) Int J Cancer , vol.121 , pp. 1366-1372
    • Zhu, H.1    Zhu, Y.2    Hu, J.3
  • 84
    • 34548427008 scopus 로고    scopus 로고
    • Mutant Bik gene transferred by cationic liposome inhibits peritoneal disseminated murine colon cancer
    • Lan KL, Yen SH, Liu RS, Shih HL, Tseng FW, Lan KH. Mutant Bik gene transferred by cationic liposome inhibits peritoneal disseminated murine colon cancer. Clin Exp Metastasis 2007; 24: 461-470.
    • (2007) Clin Exp Metastasis , vol.24 , pp. 461-470
    • Lan, K.L.1    Yen, S.H.2    Liu, R.S.3    Shih, H.L.4    Tseng, F.W.5    Lan, K.H.6
  • 85
    • 34249931357 scopus 로고    scopus 로고
    • Growth inhibition of colon cancer cells by transfection of dominant-negative apoptosis signal-regulating kinase-1
    • Kuwamura H, Tominaga K, Shiota M, et al. Growth inhibition of colon cancer cells by transfection of dominant-negative apoptosis signal-regulating kinase-1. Oncol Rep 2007; 17: 781-786.
    • (2007) Oncol Rep , vol.17 , pp. 781-786
    • Kuwamura, H.1    Tominaga, K.2    Shiota, M.3
  • 86
    • 1642336478 scopus 로고    scopus 로고
    • Gene transfer: Bax to the future for cancer therapy
    • Lemoine NR, McNeish IA. Gene transfer: Bax to the future for cancer therapy. Gut 2004; 53: 478-479.
    • (2004) Gut , vol.53 , pp. 478-479
    • Lemoine, N.R.1    McNeish, I.A.2
  • 87
    • 34248584561 scopus 로고    scopus 로고
    • Suppression of human colon tumor growth by adenoviral vector-mediated NK4 expression in an athymic mouse model
    • Jie JZ, Wang JW, Qu JG, Hung T. Suppression of human colon tumor growth by adenoviral vector-mediated NK4 expression in an athymic mouse model. World J Gastroenterol 2007; 13: 1938-1946.
    • (2007) World J Gastroenterol , vol.13 , pp. 1938-1946
    • Jie, J.Z.1    Wang, J.W.2    Qu, J.G.3    Hung, T.4
  • 88
    • 33846877421 scopus 로고    scopus 로고
    • Combining siRNAs at two different sites in the EGFR to suppress its expression, induce apoptosis, and enhance 5-fluorouracil sensitivity of colon cancer cells
    • Wu X, Deng Y, Wang G, Tao K. Combining siRNAs at two different sites in the EGFR to suppress its expression, induce apoptosis, and enhance 5-fluorouracil sensitivity of colon cancer cells. J Surg Res 2007; 138: 56-63.
    • (2007) J Surg Res , vol.138 , pp. 56-63
    • Wu, X.1    Deng, Y.2    Wang, G.3    Tao, K.4
  • 89
    • 33747130820 scopus 로고    scopus 로고
    • Biology of insulin-like growth factor binding protein-4 and its role in cancer (review)
    • Durai R, Davies M, Yang W, et al. Biology of insulin-like growth factor binding protein-4 and its role in cancer (review). Int J Oncol 2006; 28: 1317-1325.
    • (2006) Int J Oncol , vol.28 , pp. 1317-1325
    • Durai, R.1    Davies, M.2    Yang, W.3
  • 90
    • 34547902841 scopus 로고    scopus 로고
    • Increased apoptosis and decreased proliferation of colorectal cancer cells using insulin-like growth factor binding protein-4 gene delivered locally by gene transfer
    • Durai R, Yang SY, Sales KM, Seifalian AM, Goldspink G, Winslet MC. Increased apoptosis and decreased proliferation of colorectal cancer cells using insulin-like growth factor binding protein-4 gene delivered locally by gene transfer. Colorectal Dis 2007; 9: 625-631.
    • (2007) Colorectal Dis , vol.9 , pp. 625-631
    • Durai, R.1    Yang, S.Y.2    Sales, K.M.3    Seifalian, A.M.4    Goldspink, G.5    Winslet, M.C.6
  • 91
    • 36049048637 scopus 로고    scopus 로고
    • Suppression of human colon cancer tumors in nude mice by siRNA CD44 gene therapy
    • Subramaniam V, Vincent IR, Gilakjan M, Jothy S. Suppression of human colon cancer tumors in nude mice by siRNA CD44 gene therapy. Exp Mol Pathol 2007; 83: 332-340.
    • (2007) Exp Mol Pathol , vol.83 , pp. 332-340
    • Subramaniam, V.1    Vincent, I.R.2    Gilakjan, M.3    Jothy, S.4
  • 92
    • 35848962534 scopus 로고    scopus 로고
    • Treatment of colon cancer cells using the cytosine deaminase/5-fluorocytosine suicide system induces apoptosis, modulation of the proteome, and Hsp90beta phosphorylation
    • Negroni L, Samson M, Guigonis JM, Rossi B, Pierrefite-Carle V, Baudoin C. Treatment of colon cancer cells using the cytosine deaminase/5-fluorocytosine suicide system induces apoptosis, modulation of the proteome, and Hsp90beta phosphorylation. Mol Cancer Ther 2007; 6: 2747-2756.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2747-2756
    • Negroni, L.1    Samson, M.2    Guigonis, J.M.3    Rossi, B.4    Pierrefite-Carle, V.5    Baudoin, C.6
  • 93
    • 0033163321 scopus 로고    scopus 로고
    • Inhibitory effect on the establishment of hepatic metastasis by transduction of the tissue plasminogen activator gene to murine colon cancer
    • Hayashi S, Yokoyama I, Namii Y, Emi N, Uchida K, Takagi H. Inhibitory effect on the establishment of hepatic metastasis by transduction of the tissue plasminogen activator gene to murine colon cancer. Cancer Gene Ther 1999; 6: 380-384.
    • (1999) Cancer Gene Ther , vol.6 , pp. 380-384
    • Hayashi, S.1    Yokoyama, I.2    Namii, Y.3    Emi, N.4    Uchida, K.5    Takagi, H.6
  • 94
    • 34047181954 scopus 로고    scopus 로고
    • Tissue-specific differential antitumour effect of molecular forms of fractalkine in a mouse model of metastatic colon cancer
    • Vitale S, Cambien B, Karimdjee BF, et al. Tissue-specific differential antitumour effect of molecular forms of fractalkine in a mouse model of metastatic colon cancer. Gut 2007; 56: 365-372.
    • (2007) Gut , vol.56 , pp. 365-372
    • Vitale, S.1    Cambien, B.2    Karimdjee, B.F.3
  • 95
    • 3042815332 scopus 로고    scopus 로고
    • The scientific and clinical value of molecular genetic changes in the intercellular gap junctions observed in colon cancer
    • Iaitskii NA, Dubina MV, Vasil'ev SV, Popov DE, Krutovskikh VA. The scientific and clinical value of molecular genetic changes in the intercellular gap junctions observed in colon cancer. Vestn Ross Akad Med Nauk 2003; 24-29.
    • (2003) Vestn Ross Akad Med Nauk , pp. 24-29
    • Iaitskii, N.A.1    Dubina, M.V.2    Vasil'ev, S.V.3    Popov, D.E.4    Krutovskikh, V.A.5
  • 96
    • 33646057310 scopus 로고    scopus 로고
    • Antisense to CDK4 inhibits the growth of human colon cancer cells HT29
    • Ye YJ, Zhu XG, Wang S, Wang YC, Sang JL.Antisense to CDK4 inhibits the growth of human colon cancer cells HT29. Zhonghua Yi Xue Za Zhi 2006; 86: 846-849.
    • (2006) Zhonghua Yi Xue Za Zhi , vol.86 , pp. 846-849
    • Ye, Y.J.1    Zhu, X.G.2    Wang, S.3    Wang, Y.C.4    Sang, J.L.5
  • 97
    • 0035863835 scopus 로고    scopus 로고
    • Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis
    • Hilliard B, Wilmen A, Seidel C, Liu TS, Goke R, Chen Y. Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune encephalomyelitis. J Immunol 2001; 166: 1314-1319.
    • (2001) J Immunol , vol.166 , pp. 1314-1319
    • Hilliard, B.1    Wilmen, A.2    Seidel, C.3    Liu, T.S.4    Goke, R.5    Chen, Y.6
  • 98
    • 6444230371 scopus 로고    scopus 로고
    • Gene therapy in colon cancer cells with a fiber-modified adenovector expressing the TRAIL gene driven by the hTERT promoter
    • Jacob D, Bahra M, Schumacher G, Neuhaus P, Fang B. Gene therapy in colon cancer cells with a fiber-modified adenovector expressing the TRAIL gene driven by the hTERT promoter. Anticancer Res 2004; 24: 3075-3079.
    • (2004) Anticancer Res , vol.24 , pp. 3075-3079
    • Jacob, D.1    Bahra, M.2    Schumacher, G.3    Neuhaus, P.4    Fang, B.5
  • 99
    • 24344482476 scopus 로고    scopus 로고
    • Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)
    • Rychahou PG, Murillo CA, Evers BM. Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL). Surgery 2005; 138: 391-397.
    • (2005) Surgery , vol.138 , pp. 391-397
    • Rychahou, P.G.1    Murillo, C.A.2    Evers, B.M.3
  • 100
    • 0036737751 scopus 로고    scopus 로고
    • Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line
    • Zhang L, Gu J, Lin T, Huang X, Roth JA, Fang B. Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line. Gene Ther 2002; 9: 1262-1270.
    • (2002) Gene Ther , vol.9 , pp. 1262-1270
    • Zhang, L.1    Gu, J.2    Lin, T.3    Huang, X.4    Roth, J.A.5    Fang, B.6
  • 101
    • 33645886052 scopus 로고    scopus 로고
    • Short interfering RNA-mediated gene silencing of vascular endothelial growth factor: Effects on cellular proliferation in colon cancer cells
    • Mulkeen AL, Silva T, Yoo PS, et al. Short interfering RNA-mediated gene silencing of vascular endothelial growth factor: effects on cellular proliferation in colon cancer cells. Arch Surg 2006; 141: 367-374.
    • (2006) Arch Surg , vol.141 , pp. 367-374
    • Mulkeen, A.L.1    Silva, T.2    Yoo, P.S.3
  • 102
    • 0038407310 scopus 로고    scopus 로고
    • Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors
    • Stoeltzing O, Ahmad SA, Liu W, et al. Angiopoietin-1 inhibits vascular permeability, angiogenesis, and growth of hepatic colon cancer tumors. Cancer Res 2003; 63: 3370-3377.
    • (2003) Cancer Res , vol.63 , pp. 3370-3377
    • Stoeltzing, O.1    Ahmad, S.A.2    Liu, W.3
  • 103
    • 0038574455 scopus 로고    scopus 로고
    • Endostatin exhibits a direct antitumor effect in addition to its antiangiogenic activity in colon cancer cells
    • Dkhissi F, Lu H, Soria C, et al. Endostatin exhibits a direct antitumor effect in addition to its antiangiogenic activity in colon cancer cells. Hum Gene Ther 2003; 14: 997-1008.
    • (2003) Hum Gene Ther , vol.14 , pp. 997-1008
    • Dkhissi, F.1    Lu, H.2    Soria, C.3
  • 104
    • 29244455327 scopus 로고    scopus 로고
    • Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954
    • Lukashev AN, Fuerer C, Chen MJ, Searle P, Iggo R. Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954. Hum Gene Ther 2005; 16: 1473-1483.
    • (2005) Hum Gene Ther , vol.16 , pp. 1473-1483
    • Lukashev, A.N.1    Fuerer, C.2    Chen, M.J.3    Searle, P.4    Iggo, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.