-
1
-
-
0025141337
-
What is the evidence that tumors are angiogenesis dependent?
-
Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst. 1990;82:4-6.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 4-6
-
-
Folkman, J.1
-
2
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J, Bach M, Rowe JW, et al. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971;285:1182-1186.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
Bach, M.2
Rowe, J.W.3
-
3
-
-
0036782278
-
VEGF and the quest for tumour angiogenesis factors
-
Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer. 2002;2:795-803.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 795-803
-
-
Ferrara, N.1
-
5
-
-
0032007140
-
Vessel counts and vascular endothelial growth factor expression in pancreatic adenocarcinoma
-
Ellis LM, Takahashi Y, Fenoglio CJ, Cleary KR, Bucana CD, Evans DB. Vessel counts and vascular endothelial growth factor expression in pancreatic adenocarcinoma. Eur J Cancer. 1998;34:337-340.
-
(1998)
Eur J Cancer
, vol.34
, pp. 337-340
-
-
Ellis, L.M.1
Takahashi, Y.2
Fenoglio, C.J.3
Cleary, K.R.4
Bucana, C.D.5
Evans, D.B.6
-
6
-
-
0031458922
-
Expression and localization of the vascular endothelial growth factor family in ovarian epithelial tumors
-
Sowter HM, Corps AN, Evans AL, Clark DE, Charnock-Jones DS, Smith SK. Expression and localization of the vascular endothelial growth factor family in ovarian epithelial tumors. Lab Invest. 1997;77:607-614.
-
(1997)
Lab Invest
, vol.77
, pp. 607-614
-
-
Sowter, H.M.1
Corps, A.N.2
Evans, A.L.3
Clark, D.E.4
Charnock-Jones, D.S.5
Smith, S.K.6
-
7
-
-
0033061154
-
Expression pattern of vascular endothelial growth factor isoform is closely correlated with tumour stage and vascularisation in renal cell carcinoma
-
Tomisawa M, Tokunaga T, Oshika Y, et al. Expression pattern of vascular endothelial growth factor isoform is closely correlated with tumour stage and vascularisation in renal cell carcinoma. Eur J Cancer. 1999;35:133-137.
-
(1999)
Eur J Cancer
, vol.35
, pp. 133-137
-
-
Tomisawa, M.1
Tokunaga, T.2
Oshika, Y.3
-
8
-
-
1842328560
-
Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer
-
Volm M, Koomagi R, Mattern J. Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer. Int J Cancer. 1997;74:64-68.
-
(1997)
Int J Cancer
, vol.74
, pp. 64-68
-
-
Volm, M.1
Koomagi, R.2
Mattern, J.3
-
9
-
-
0029935566
-
Expression of vascular endothelial growth factor, its receptor, and other angiogenic factors in human breast cancer
-
Yoshiji H, Gomez DE, Shibuya M, Thorgeirsson UP. Expression of vascular endothelial growth factor, its receptor, and other angiogenic factors in human breast cancer. Cancer Res. 1996;56:2013-2016.
-
(1996)
Cancer Res
, vol.56
, pp. 2013-2016
-
-
Yoshiji, H.1
Gomez, D.E.2
Shibuya, M.3
Thorgeirsson, U.P.4
-
10
-
-
0030043446
-
Cancer statistics, 1996
-
Parker SL, Tong T, Bolden S, Wingo PA. Cancer statistics, 1996. CA Cancer J Clin. 1996;46:5-27.
-
(1996)
CA Cancer J Clin
, vol.46
, pp. 5-27
-
-
Parker, S.L.1
Tong, T.2
Bolden, S.3
Wingo, P.A.4
-
11
-
-
0033941120
-
Expression of vascular endothelial growth factor can predict event-free survival in stage II colon cancer
-
Cascinu S, Staccioli MP, Gasparini G, et al. Expression of vascular endothelial growth factor can predict event-free survival in stage II colon cancer. Clin Cancer Res. 2000;6:2803-2807.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2803-2807
-
-
Cascinu, S.1
Staccioli, M.P.2
Gasparini, G.3
-
12
-
-
0031789314
-
Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer
-
Ishigami SI, Arii S, Furutani M, et al. Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer. Br J Cancer. 1998;78:1379-1384.
-
(1998)
Br J Cancer
, vol.78
, pp. 1379-1384
-
-
Ishigami, S.I.1
Arii, S.2
Furutani, M.3
-
13
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335-2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
14
-
-
0035394833
-
Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis
-
Viloria-Petit A, Crombet T, Jothy S, et al. Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis. Cancer Res. 2001;61:5090-5101.
-
(2001)
Cancer Res
, vol.61
, pp. 5090-5101
-
-
Viloria-Petit, A.1
Crombet, T.2
Jothy, S.3
-
15
-
-
9644275599
-
Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: Therapeutic strategy for herpetic stromal keratitis
-
Kim B, Tang QQ, Biswas PS, et al. Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis. Am J Pathol. 2004;165:2177-2185.
-
(2004)
Am J Pathol
, vol.165
, pp. 2177-2185
-
-
Kim, B.1
Tang, Q.Q.2
Biswas, P.S.3
-
16
-
-
14844320045
-
Modulation of angiogenesis with siRNA inhibitors for novel therapeutics
-
Lu PY, Xie FY, Woodle MC. Modulation of angiogenesis with siRNA inhibitors for novel therapeutics. Trends Mol Med. 2005;11:104-113.
-
(2005)
Trends Mol Med
, vol.11
, pp. 104-113
-
-
Lu, P.Y.1
Xie, F.Y.2
Woodle, M.C.3
-
17
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 2001;15:188-200.
-
(2001)
Genes Dev
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
18
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu SQ, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998;391:806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.Q.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
19
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature. 2001;409:363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
20
-
-
0033032991
-
Molecular mediators of tumor angiogenesis: Enhanced expression and activation of vascular endothelial growth factor receptor KDR in primary breast cancer
-
Kranz A, Mattfeldt T, Waltenberger J. Molecular mediators of tumor angiogenesis: enhanced expression and activation of vascular endothelial growth factor receptor KDR in primary breast cancer. Int J Cancer. 1999;84:293-298.
-
(1999)
Int J Cancer
, vol.84
, pp. 293-298
-
-
Kranz, A.1
Mattfeldt, T.2
Waltenberger, J.3
-
21
-
-
0034891532
-
Vascular endothelial growth factor-mediated autocrine stimulation of prostate tumor cells coincides with progression to a malignant phenotype
-
Soker S, Kaefer M, Johnson M, Klagsbrun M, Atala A, Freeman MR. Vascular endothelial growth factor-mediated autocrine stimulation of prostate tumor cells coincides with progression to a malignant phenotype. Am J Pathol. 2001;159:651-659.
-
(2001)
Am J Pathol
, vol.159
, pp. 651-659
-
-
Soker, S.1
Kaefer, M.2
Johnson, M.3
Klagsbrun, M.4
Atala, A.5
Freeman, M.R.6
-
22
-
-
0034807692
-
Vascular endothelial growth factor: Acting as an autocrine growth factor for human gastric adenocarcinoma cell MGC803
-
Tian X, Song SM, Wu J, Meng L, Dong ZW, Shou CC. Vascular endothelial growth factor: acting as an autocrine growth factor for human gastric adenocarcinoma cell MGC803. Biochem Biophys Res Commun. 2001;286:505-512.
-
(2001)
Biochem Biophys Res Commun
, vol.286
, pp. 505-512
-
-
Tian, X.1
Song, S.M.2
Wu, J.3
Meng, L.4
Dong, Z.W.5
Shou, C.C.6
-
23
-
-
0035422178
-
Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells
-
Bachelder RE, Crago A, Chung J, et al. Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells. Cancer Res. 2001;61:5736-5740.
-
(2001)
Cancer Res
, vol.61
, pp. 5736-5740
-
-
Bachelder, R.E.1
Crago, A.2
Chung, J.3
-
24
-
-
0037115522
-
Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4
-
Bachelder RE, Wendt MA, Mercurio AM. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res. 2002;62:7203-7206.
-
(2002)
Cancer Res
, vol.62
, pp. 7203-7206
-
-
Bachelder, R.E.1
Wendt, M.A.2
Mercurio, A.M.3
-
25
-
-
0035885932
-
Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors
-
Masood R, Cai J, Zheng T, Smith DL, Hinton DR, Gill PS. Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors. Blood. 2001;98:1904-1913.
-
(2001)
Blood
, vol.98
, pp. 1904-1913
-
-
Masood, R.1
Cai, J.2
Zheng, T.3
Smith, D.L.4
Hinton, D.R.5
Gill, P.S.6
-
26
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
Elbashir SM, Harborth J, Weber K, Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods. 2002;26:199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
27
-
-
0042173218
-
SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth
-
Filleur S, Courtin A, Ait-Si-Ali S, et al. SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth. Cancer Res. 2003;63:3919-3922.
-
(2003)
Cancer Res
, vol.63
, pp. 3919-3922
-
-
Filleur, S.1
Courtin, A.2
Ait-Si-Ali, S.3
-
28
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001;411:494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
29
-
-
0029738062
-
Significance of vascular endothelial growth factor messenger RNA expression in primary lung cancer
-
Ohta Y, Endo Y, Tanaka M, et al. Significance of vascular endothelial growth factor messenger RNA expression in primary lung cancer. Clin Cancer Res. 1996;2:1411-1416.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1411-1416
-
-
Ohta, Y.1
Endo, Y.2
Tanaka, M.3
-
30
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ, Holash J. Vascular-specific growth factors and blood vessel formation. Nature. 2000;407:242-248.
-
(2000)
Nature
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
Davis, S.2
Gale, N.W.3
Rudge, J.S.4
Wiegand, S.J.5
Holash, J.6
-
31
-
-
0034925637
-
Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells
-
Price DJ, Miralem T, Jiang SX, Steinberg R, Avraham H. Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells. Cell Growth Differ. 2001;12:129-135.
-
(2001)
Cell Growth Differ
, vol.12
, pp. 129-135
-
-
Price, D.J.1
Miralem, T.2
Jiang, S.X.3
Steinberg, R.4
Avraham, H.5
-
32
-
-
0036468930
-
A potential autocrine role for vascular endothelial growth factor in prostate cancer
-
Jackson MW, Roberts JS, Heckford SE, et al. A potential autocrine role for vascular endothelial growth factor in prostate cancer. Cancer Res. 2002;62:854-859.
-
(2002)
Cancer Res
, vol.62
, pp. 854-859
-
-
Jackson, M.W.1
Roberts, J.S.2
Heckford, S.E.3
-
33
-
-
18744374621
-
VEGF contributes to mammary tumor growth in transgenic mice through paracrine and autocrine mechanisms
-
Schoeffner DJ, Matheny SL, Akahane T, et al. VEGF contributes to mammary tumor growth in transgenic mice through paracrine and autocrine mechanisms. Lab Invest. 2005;85:608-623.
-
(2005)
Lab Invest
, vol.85
, pp. 608-623
-
-
Schoeffner, D.J.1
Matheny, S.L.2
Akahane, T.3
-
34
-
-
0042882883
-
Clinical significance of angiogenesis in gastrointestinal cancers: A target for novel prognostic and therapeutic approaches
-
Poon RTP, Fan ST, Wong J. Clinical significance of angiogenesis in gastrointestinal cancers: a target for novel prognostic and therapeutic approaches. Ann Surg. 2003;238:9-28.
-
(2003)
Ann Surg
, vol.238
, pp. 9-28
-
-
Poon, R.T.P.1
Fan, S.T.2
Wong, J.3
-
35
-
-
4644316534
-
Systemic siRNA-mediated gene silencing: A new approach to targeted therapy of cancer
-
Duxbury MS, Matros E, Ito H, Zinner MJ, Ashley SW, Whang EE. Systemic siRNA-mediated gene silencing: a new approach to targeted therapy of cancer. Ann Surg. 2004;240:667-674.
-
(2004)
Ann Surg
, vol.240
, pp. 667-674
-
-
Duxbury, M.S.1
Matros, E.2
Ito, H.3
Zinner, M.J.4
Ashley, S.W.5
Whang, E.E.6
-
36
-
-
14544298301
-
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
-
Schiffelers RM, Ansari A, Xu J, et al. Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res. 2004;32:e149.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Schiffelers, R.M.1
Ansari, A.2
Xu, J.3
-
37
-
-
21344445924
-
Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A
-
Detwiller KY, Fernando NT, Segal NH, Ryeom SW, D'Amore PA, Yoon SS. Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A. Cancer Res. 2005;65:5881-5889.
-
(2005)
Cancer Res
, vol.65
, pp. 5881-5889
-
-
Detwiller, K.Y.1
Fernando, N.T.2
Segal, N.H.3
Ryeom, S.W.4
D'Amore, P.A.5
Yoon, S.S.6
-
38
-
-
17644403503
-
A small interfering RNA targeting vascular endothelial growth factor inhibits Ewing's sarcoma growth in a xenograft mouse model
-
Guan H, Zhou ZC, Wang H, Jia SF, Liu WB, Kleinerman ES. A small interfering RNA targeting vascular endothelial growth factor inhibits Ewing's sarcoma growth in a xenograft mouse model. Clin Cancer Res. 2005;11:2662-2669.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2662-2669
-
-
Guan, H.1
Zhou, Z.C.2
Wang, H.3
Jia, S.F.4
Liu, W.B.5
Kleinerman, E.S.6
-
39
-
-
23844535465
-
Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells
-
Kim SJ, Seo JH, Lee YJ, et al. Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells. Oncology. 2005;68:204-211.
-
(2005)
Oncology
, vol.68
, pp. 204-211
-
-
Kim, S.J.1
Seo, J.H.2
Lee, Y.J.3
-
40
-
-
9144269918
-
Elevated perioperative serum vascular endothelial growth factor levels in patients with colon carcinoma
-
De Vita F, Orditura M, Lieto E, et al. Elevated perioperative serum vascular endothelial growth factor levels in patients with colon carcinoma. Cancer. 2004;100:270-278.
-
(2004)
Cancer
, vol.100
, pp. 270-278
-
-
De Vita, F.1
Orditura, M.2
Lieto, E.3
-
41
-
-
0034075041
-
Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients
-
Lee JC, Chow NH, Wang ST, Huang SM. Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients. Eur J Cancer. 2000;36:748-753.
-
(2000)
Eur J Cancer
, vol.36
, pp. 748-753
-
-
Lee, J.C.1
Chow, N.H.2
Wang, S.T.3
Huang, S.M.4
-
42
-
-
84970070220
-
Expression of vascular endothelial growth-factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon-cancer
-
Takahashi Y, Kitadai Y, Bucana CD, Cleary KR, Ellis LM. Expression of vascular endothelial growth-factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon-cancer. Cancer Res. 1995;55:3964-3968.
-
(1995)
Cancer Res
, vol.55
, pp. 3964-3968
-
-
Takahashi, Y.1
Kitadai, Y.2
Bucana, C.D.3
Cleary, K.R.4
Ellis, L.M.5
-
43
-
-
22144471081
-
Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC #704865) in patients with advanced non-squamous non-small cell lung cancer (NSCLC): An Eastern Cooperative Oncology Group (ECOG) Trial - E4599
-
Sandler AB, Gray R, Brahmer J, et al. Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC #704865) in patients with advanced non-squamous non-small cell lung cancer (NSCLC): an Eastern Cooperative Oncology Group (ECOG) Trial - E4599. J Clin Oncol. 2005;23(pt 1, suppl):2S.
-
(2005)
J Clin Oncol
, vol.23
, Issue.PART 1 SUPPL.
-
-
Sandler, A.B.1
Gray, R.2
Brahmer, J.3
|