메뉴 건너뛰기




Volumn 141, Issue 4, 2006, Pages 367-374

Short interfering RNA-mediated gene silencing of vascular endothelial growth factor: Effects on cellular proliferation in colon cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

SMALL CYTOPLASMIC RNA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

EID: 33645886052     PISSN: 00040010     EISSN: 15383644     Source Type: Journal    
DOI: 10.1001/archsurg.141.4.367     Document Type: Article
Times cited : (36)

References (43)
  • 1
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst. 1990;82:4-6.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 2
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J, Bach M, Rowe JW, et al. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971;285:1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1    Bach, M.2    Rowe, J.W.3
  • 3
    • 0036782278 scopus 로고    scopus 로고
    • VEGF and the quest for tumour angiogenesis factors
    • Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer. 2002;2:795-803.
    • (2002) Nat Rev Cancer , vol.2 , pp. 795-803
    • Ferrara, N.1
  • 4
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med. 2003;9:669-676.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 6
    • 0031458922 scopus 로고    scopus 로고
    • Expression and localization of the vascular endothelial growth factor family in ovarian epithelial tumors
    • Sowter HM, Corps AN, Evans AL, Clark DE, Charnock-Jones DS, Smith SK. Expression and localization of the vascular endothelial growth factor family in ovarian epithelial tumors. Lab Invest. 1997;77:607-614.
    • (1997) Lab Invest , vol.77 , pp. 607-614
    • Sowter, H.M.1    Corps, A.N.2    Evans, A.L.3    Clark, D.E.4    Charnock-Jones, D.S.5    Smith, S.K.6
  • 7
    • 0033061154 scopus 로고    scopus 로고
    • Expression pattern of vascular endothelial growth factor isoform is closely correlated with tumour stage and vascularisation in renal cell carcinoma
    • Tomisawa M, Tokunaga T, Oshika Y, et al. Expression pattern of vascular endothelial growth factor isoform is closely correlated with tumour stage and vascularisation in renal cell carcinoma. Eur J Cancer. 1999;35:133-137.
    • (1999) Eur J Cancer , vol.35 , pp. 133-137
    • Tomisawa, M.1    Tokunaga, T.2    Oshika, Y.3
  • 8
    • 1842328560 scopus 로고    scopus 로고
    • Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer
    • Volm M, Koomagi R, Mattern J. Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer. Int J Cancer. 1997;74:64-68.
    • (1997) Int J Cancer , vol.74 , pp. 64-68
    • Volm, M.1    Koomagi, R.2    Mattern, J.3
  • 9
    • 0029935566 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor, its receptor, and other angiogenic factors in human breast cancer
    • Yoshiji H, Gomez DE, Shibuya M, Thorgeirsson UP. Expression of vascular endothelial growth factor, its receptor, and other angiogenic factors in human breast cancer. Cancer Res. 1996;56:2013-2016.
    • (1996) Cancer Res , vol.56 , pp. 2013-2016
    • Yoshiji, H.1    Gomez, D.E.2    Shibuya, M.3    Thorgeirsson, U.P.4
  • 11
    • 0033941120 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor can predict event-free survival in stage II colon cancer
    • Cascinu S, Staccioli MP, Gasparini G, et al. Expression of vascular endothelial growth factor can predict event-free survival in stage II colon cancer. Clin Cancer Res. 2000;6:2803-2807.
    • (2000) Clin Cancer Res , vol.6 , pp. 2803-2807
    • Cascinu, S.1    Staccioli, M.P.2    Gasparini, G.3
  • 12
    • 0031789314 scopus 로고    scopus 로고
    • Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer
    • Ishigami SI, Arii S, Furutani M, et al. Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer. Br J Cancer. 1998;78:1379-1384.
    • (1998) Br J Cancer , vol.78 , pp. 1379-1384
    • Ishigami, S.I.1    Arii, S.2    Furutani, M.3
  • 13
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 14
    • 0035394833 scopus 로고    scopus 로고
    • Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: A role for altered tumor angiogenesis
    • Viloria-Petit A, Crombet T, Jothy S, et al. Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis. Cancer Res. 2001;61:5090-5101.
    • (2001) Cancer Res , vol.61 , pp. 5090-5101
    • Viloria-Petit, A.1    Crombet, T.2    Jothy, S.3
  • 15
    • 9644275599 scopus 로고    scopus 로고
    • Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: Therapeutic strategy for herpetic stromal keratitis
    • Kim B, Tang QQ, Biswas PS, et al. Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis. Am J Pathol. 2004;165:2177-2185.
    • (2004) Am J Pathol , vol.165 , pp. 2177-2185
    • Kim, B.1    Tang, Q.Q.2    Biswas, P.S.3
  • 16
    • 14844320045 scopus 로고    scopus 로고
    • Modulation of angiogenesis with siRNA inhibitors for novel therapeutics
    • Lu PY, Xie FY, Woodle MC. Modulation of angiogenesis with siRNA inhibitors for novel therapeutics. Trends Mol Med. 2005;11:104-113.
    • (2005) Trends Mol Med , vol.11 , pp. 104-113
    • Lu, P.Y.1    Xie, F.Y.2    Woodle, M.C.3
  • 17
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 2001;15:188-200.
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 18
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu SQ, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998;391:806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.Q.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 19
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature. 2001;409:363-366.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 20
    • 0033032991 scopus 로고    scopus 로고
    • Molecular mediators of tumor angiogenesis: Enhanced expression and activation of vascular endothelial growth factor receptor KDR in primary breast cancer
    • Kranz A, Mattfeldt T, Waltenberger J. Molecular mediators of tumor angiogenesis: enhanced expression and activation of vascular endothelial growth factor receptor KDR in primary breast cancer. Int J Cancer. 1999;84:293-298.
    • (1999) Int J Cancer , vol.84 , pp. 293-298
    • Kranz, A.1    Mattfeldt, T.2    Waltenberger, J.3
  • 21
    • 0034891532 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-mediated autocrine stimulation of prostate tumor cells coincides with progression to a malignant phenotype
    • Soker S, Kaefer M, Johnson M, Klagsbrun M, Atala A, Freeman MR. Vascular endothelial growth factor-mediated autocrine stimulation of prostate tumor cells coincides with progression to a malignant phenotype. Am J Pathol. 2001;159:651-659.
    • (2001) Am J Pathol , vol.159 , pp. 651-659
    • Soker, S.1    Kaefer, M.2    Johnson, M.3    Klagsbrun, M.4    Atala, A.5    Freeman, M.R.6
  • 22
    • 0034807692 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Acting as an autocrine growth factor for human gastric adenocarcinoma cell MGC803
    • Tian X, Song SM, Wu J, Meng L, Dong ZW, Shou CC. Vascular endothelial growth factor: acting as an autocrine growth factor for human gastric adenocarcinoma cell MGC803. Biochem Biophys Res Commun. 2001;286:505-512.
    • (2001) Biochem Biophys Res Commun , vol.286 , pp. 505-512
    • Tian, X.1    Song, S.M.2    Wu, J.3    Meng, L.4    Dong, Z.W.5    Shou, C.C.6
  • 23
    • 0035422178 scopus 로고    scopus 로고
    • Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells
    • Bachelder RE, Crago A, Chung J, et al. Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells. Cancer Res. 2001;61:5736-5740.
    • (2001) Cancer Res , vol.61 , pp. 5736-5740
    • Bachelder, R.E.1    Crago, A.2    Chung, J.3
  • 24
    • 0037115522 scopus 로고    scopus 로고
    • Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4
    • Bachelder RE, Wendt MA, Mercurio AM. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res. 2002;62:7203-7206.
    • (2002) Cancer Res , vol.62 , pp. 7203-7206
    • Bachelder, R.E.1    Wendt, M.A.2    Mercurio, A.M.3
  • 25
    • 0035885932 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors
    • Masood R, Cai J, Zheng T, Smith DL, Hinton DR, Gill PS. Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors. Blood. 2001;98:1904-1913.
    • (2001) Blood , vol.98 , pp. 1904-1913
    • Masood, R.1    Cai, J.2    Zheng, T.3    Smith, D.L.4    Hinton, D.R.5    Gill, P.S.6
  • 26
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • Elbashir SM, Harborth J, Weber K, Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods. 2002;26:199-213.
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 27
    • 0042173218 scopus 로고    scopus 로고
    • SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth
    • Filleur S, Courtin A, Ait-Si-Ali S, et al. SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth. Cancer Res. 2003;63:3919-3922.
    • (2003) Cancer Res , vol.63 , pp. 3919-3922
    • Filleur, S.1    Courtin, A.2    Ait-Si-Ali, S.3
  • 28
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001;411:494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 29
    • 0029738062 scopus 로고    scopus 로고
    • Significance of vascular endothelial growth factor messenger RNA expression in primary lung cancer
    • Ohta Y, Endo Y, Tanaka M, et al. Significance of vascular endothelial growth factor messenger RNA expression in primary lung cancer. Clin Cancer Res. 1996;2:1411-1416.
    • (1996) Clin Cancer Res , vol.2 , pp. 1411-1416
    • Ohta, Y.1    Endo, Y.2    Tanaka, M.3
  • 31
    • 0034925637 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells
    • Price DJ, Miralem T, Jiang SX, Steinberg R, Avraham H. Role of vascular endothelial growth factor in the stimulation of cellular invasion and signaling of breast cancer cells. Cell Growth Differ. 2001;12:129-135.
    • (2001) Cell Growth Differ , vol.12 , pp. 129-135
    • Price, D.J.1    Miralem, T.2    Jiang, S.X.3    Steinberg, R.4    Avraham, H.5
  • 32
    • 0036468930 scopus 로고    scopus 로고
    • A potential autocrine role for vascular endothelial growth factor in prostate cancer
    • Jackson MW, Roberts JS, Heckford SE, et al. A potential autocrine role for vascular endothelial growth factor in prostate cancer. Cancer Res. 2002;62:854-859.
    • (2002) Cancer Res , vol.62 , pp. 854-859
    • Jackson, M.W.1    Roberts, J.S.2    Heckford, S.E.3
  • 33
    • 18744374621 scopus 로고    scopus 로고
    • VEGF contributes to mammary tumor growth in transgenic mice through paracrine and autocrine mechanisms
    • Schoeffner DJ, Matheny SL, Akahane T, et al. VEGF contributes to mammary tumor growth in transgenic mice through paracrine and autocrine mechanisms. Lab Invest. 2005;85:608-623.
    • (2005) Lab Invest , vol.85 , pp. 608-623
    • Schoeffner, D.J.1    Matheny, S.L.2    Akahane, T.3
  • 34
    • 0042882883 scopus 로고    scopus 로고
    • Clinical significance of angiogenesis in gastrointestinal cancers: A target for novel prognostic and therapeutic approaches
    • Poon RTP, Fan ST, Wong J. Clinical significance of angiogenesis in gastrointestinal cancers: a target for novel prognostic and therapeutic approaches. Ann Surg. 2003;238:9-28.
    • (2003) Ann Surg , vol.238 , pp. 9-28
    • Poon, R.T.P.1    Fan, S.T.2    Wong, J.3
  • 35
    • 4644316534 scopus 로고    scopus 로고
    • Systemic siRNA-mediated gene silencing: A new approach to targeted therapy of cancer
    • Duxbury MS, Matros E, Ito H, Zinner MJ, Ashley SW, Whang EE. Systemic siRNA-mediated gene silencing: a new approach to targeted therapy of cancer. Ann Surg. 2004;240:667-674.
    • (2004) Ann Surg , vol.240 , pp. 667-674
    • Duxbury, M.S.1    Matros, E.2    Ito, H.3    Zinner, M.J.4    Ashley, S.W.5    Whang, E.E.6
  • 36
    • 14544298301 scopus 로고    scopus 로고
    • Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
    • Schiffelers RM, Ansari A, Xu J, et al. Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res. 2004;32:e149.
    • (2004) Nucleic Acids Res , vol.32
    • Schiffelers, R.M.1    Ansari, A.2    Xu, J.3
  • 37
    • 21344445924 scopus 로고    scopus 로고
    • Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A
    • Detwiller KY, Fernando NT, Segal NH, Ryeom SW, D'Amore PA, Yoon SS. Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A. Cancer Res. 2005;65:5881-5889.
    • (2005) Cancer Res , vol.65 , pp. 5881-5889
    • Detwiller, K.Y.1    Fernando, N.T.2    Segal, N.H.3    Ryeom, S.W.4    D'Amore, P.A.5    Yoon, S.S.6
  • 38
    • 17644403503 scopus 로고    scopus 로고
    • A small interfering RNA targeting vascular endothelial growth factor inhibits Ewing's sarcoma growth in a xenograft mouse model
    • Guan H, Zhou ZC, Wang H, Jia SF, Liu WB, Kleinerman ES. A small interfering RNA targeting vascular endothelial growth factor inhibits Ewing's sarcoma growth in a xenograft mouse model. Clin Cancer Res. 2005;11:2662-2669.
    • (2005) Clin Cancer Res , vol.11 , pp. 2662-2669
    • Guan, H.1    Zhou, Z.C.2    Wang, H.3    Jia, S.F.4    Liu, W.B.5    Kleinerman, E.S.6
  • 39
    • 23844535465 scopus 로고    scopus 로고
    • Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells
    • Kim SJ, Seo JH, Lee YJ, et al. Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells. Oncology. 2005;68:204-211.
    • (2005) Oncology , vol.68 , pp. 204-211
    • Kim, S.J.1    Seo, J.H.2    Lee, Y.J.3
  • 40
    • 9144269918 scopus 로고    scopus 로고
    • Elevated perioperative serum vascular endothelial growth factor levels in patients with colon carcinoma
    • De Vita F, Orditura M, Lieto E, et al. Elevated perioperative serum vascular endothelial growth factor levels in patients with colon carcinoma. Cancer. 2004;100:270-278.
    • (2004) Cancer , vol.100 , pp. 270-278
    • De Vita, F.1    Orditura, M.2    Lieto, E.3
  • 41
    • 0034075041 scopus 로고    scopus 로고
    • Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients
    • Lee JC, Chow NH, Wang ST, Huang SM. Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients. Eur J Cancer. 2000;36:748-753.
    • (2000) Eur J Cancer , vol.36 , pp. 748-753
    • Lee, J.C.1    Chow, N.H.2    Wang, S.T.3    Huang, S.M.4
  • 42
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth-factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon-cancer
    • Takahashi Y, Kitadai Y, Bucana CD, Cleary KR, Ellis LM. Expression of vascular endothelial growth-factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon-cancer. Cancer Res. 1995;55:3964-3968.
    • (1995) Cancer Res , vol.55 , pp. 3964-3968
    • Takahashi, Y.1    Kitadai, Y.2    Bucana, C.D.3    Cleary, K.R.4    Ellis, L.M.5
  • 43
    • 22144471081 scopus 로고    scopus 로고
    • Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC #704865) in patients with advanced non-squamous non-small cell lung cancer (NSCLC): An Eastern Cooperative Oncology Group (ECOG) Trial - E4599
    • Sandler AB, Gray R, Brahmer J, et al. Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC #704865) in patients with advanced non-squamous non-small cell lung cancer (NSCLC): an Eastern Cooperative Oncology Group (ECOG) Trial - E4599. J Clin Oncol. 2005;23(pt 1, suppl):2S.
    • (2005) J Clin Oncol , vol.23 , Issue.PART 1 SUPPL.
    • Sandler, A.B.1    Gray, R.2    Brahmer, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.