Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of Escherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine

Cancer Gene Therapy

Volumn 7, Issue 7, 2000, Pages 1015-1022

  Koyama, Fumikazu ^a   Sawada, Hidetomo ^a   Hirao, Tomoko ^a   Fujii, Hisao ^a   Hamada, Hirofumi ^b   Nakano, Hiroshige ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

^b CANCER INSTITUTE   (Japan)

Author keywords

Colon cancer; Cytosine deaminase; Gene therapy; Uracil phosphoribosyltransferase

Indexed keywords

CYTOSINE DEAMINASE; FLOXURIDINE PHOSPHATE; FLUCYTOSINE; FLUOROURIDINE TRIPHOSPHATE; RNA; THYMIDYLATE SYNTHASE; URACIL PHOSPHORIBOSYLTRANSFERASE;

ADENOVIRUS; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; COLON CANCER; CONTROLLED STUDY; DRUG EFFICACY; ENZYME INHIBITION; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PRIORITY JOURNAL; SUICIDE GENE; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALIA; ESCHERICHIA COLI; MUS MUSCULUS;

EID: 0033914616     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700189     Document Type: Article

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