5-fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells

Journal of Gene Medicine

Volumn 5, Issue 4, 2003, Pages 287-299

  Uchida, Hiroaki ^a,b   Shinoura, Nobusada ^c   Kitayama, Joji ^b   Watanabe, Toshiaki ^b   Nagawa, Hirokazu ^b   Hamada, Hirofumi ^a  

^a SAPPORO MEDICAL UNIVERSITY   (Japan)

^b THE UNIVERSITY OF TOKYO   (Japan)

^c Kamagome Metropolitan Hospital   (Japan)

Author keywords

5 fluorouracil; Adenovirus; Apoptosis; Caspase 8; Colorectal cancer; Gene therapy

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; CASPASE 8; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DNA FRAGMENT; FLUOROURACIL; GENE PRODUCT; GREEN FLUORESCENT PROTEIN; ANTINEOPLASTIC ANTIMETABOLITE; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; CASPASE 9; CDKN1A PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; ENZYME PRECURSOR; TUMOR SUPPRESSOR PROTEIN;

ADENOVIRUS; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL DIVISION; COLON CANCER; COLORECTAL CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG EXPOSURE; DRUG POTENCY; ENZYME ACTIVATION; GENE OVEREXPRESSION; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING; CARCINOMA; CELL CULTURE; COLON TUMOR; COLORECTAL TUMOR; DRUG EFFECT; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY;

ADENOVIRIDAE; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; CARCINOMA; CASPASE 8; CASPASE 9; CASPASES; CELL CYCLE PROTEINS; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; ENZYME ACTIVATION; ENZYME PRECURSORS; FLUOROURACIL; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE TRANSFER TECHNIQUES; HUMANS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0642275635     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.339     Document Type: Article

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