Prolonged exposure to IL-1β and IFNγ induces necrosis of L929 tumor cells via a p38MAPK/NF-κB/NO-dependent mechanism

Oncogene

Volumn 27, Issue 27, 2008, Pages 3780-3788

  Vercammen, E ^a,b   Staal, J ^a,b   Van Den Broeke, A ^a,b   Haegman, M ^a,b   Vereecke, L ^a,b   Schotte, P ^a,b   Beyaert, R ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Interferon; Interleukin 1; Necrosis; NF B; Nitric oxide

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CASPASE; GAMMA INTERFERON; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; SC 514; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL STRAIN L 929; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG MECHANISM; ENZYME SYNTHESIS; LONG TERM EXPOSURE; NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR CELL;

ANIMALS; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; INTERFERON TYPE II; INTERLEUKIN-1BETA; MICE; NECROSIS; NF-KAPPA B; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 42249110095     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.4     Document Type: Article

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