TTI-237: A novel microtubule-active compound with in vivo antitumor activity

Cancer Research

Volumn 68, Issue 7, 2008, Pages 2292-2300

  Beyer, Carl F ^a   Zhang, Nan ^a   Hernandez, Richard ^a   Vitale, Danielle ^a   Lucas, Judy ^a   Nguyen, Thai ^a   Discafani, Carolyn ^a   Ayral Kaloustian, Semiramis ^a   Gibbons, James J ^a  

^a WYETH RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; COLCHICINE; DOCETAXEL; MICROTUBULE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; TTI 237; TUBULIN; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; COLON CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG BINDING; DRUG INHIBITION; DRUG STRUCTURE; FEMALE; FLOW CYTOMETRY; GLIOBLASTOMA; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; MITOSIS RATE; MOUSE; MULTINUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SPINDLE CELL; TURBIDITY; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HELA CELLS; HUMANS; HYDROCARBONS, HALOGENATED; MICE; MICE, NUDE; MICROTUBULES; TRIAZOLES; TUBULIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 42049123226     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-1420     Document Type: Article

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