Pulse treatment of interphasic HeLa cells with nanomolar doses of docetaxel affects centrosome organization and leads to catastrophic exit of mitosis

Journal of Cell Science

Volumn 110, Issue 19, 1997, Pages 2403-2415

  Paoletti, Anne ^a,c   Giocanti, Nicole ^b   Favaudon, Vincent ^b   Bornens, Michel ^a  

^a INSTITUT CURIE   (France)

^b INSTITUT CURIE   (France)

^c Columbia University ^*  (United States)

Author keywords

Cell cycle; Centrosome; Docetaxel; Microtubule drug; Mitosis; Paclitaxel; Taxol; Taxotere

Indexed keywords

EID: 0008379535     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Andreassen, P. R. and Margolis, R. L. (1994). Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells. J. Cell Biol. 127, 789-802.
2. 2/M and enters vesicles at anaphase. EMBO J. 8, 3985-3995.
3. Bailly, E. and Bornens, M. (1992). Cell biology. Centrosome and cell division [news]. Nature 355, 300-301.
4. Bobinnec, Y., Moudjou, M., Mir, L., Eddé, B. and Bornens, M. (1995). A role for centrioles in centrosome organisation. Mol. Biol. Cell (suppl.) 6, 41 a.
5. Bornens, M. (1992). Structure and function of isolated centrosomes. In The Centrosome (ed. V. I. Kalnins), pp. 1-43. San Diego: Academic Press.
6. Cleveland, D. W. (1995). NuMA: a protein involved in nuclear structure, spindle assembly, and nuclear re-formation. Trends Cell Biol. 5, 60-64.
7. Compton, D. A., Szilak, I. and Cleveland, D. W. (1992). Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis. J. Cell Biol. 116, 1395-1408.
8. Compton, D. A. and Luo, C. (1995). Mutation of the predicted p34cdc2 phosphorylation sites in NuMA impair the assembly of the mitotic spindle and block mitosis. J. Cell Sci. 108, 621-363.
9. Demarcq, C., Bastian, G. and Remvikos, Y. (1992). BrdUrd/DNA flow cytometry analysis demonstrates cis-diamminedichloroplatinum(II)-induced multiple cell cycle modifications on human lung carcinoma cells. Cytometry 13, 416-422.
10. Gaglio, T., Saredi, A. and Compton, D. A. (1995). NuMA is required for the organization of microtubules into aster-like mitotic arrays. J. Cell Biol. 131, 693-708.
11. Gaglio, T., Saredi, A., Bingham, J. B., Hasbani, M. J., Gill, S. R., Schroer, T. A. and Compton, D. A. (1996). Opposing motor activities are required for the organization of the mammalian mitotic spindle pole. J. Cell Biol. 135, 399-414.
12. Gosti-Testu, F., Marty, M. C., Berges, J., Maunoury, R. and Bornens, M. (1986). Identification of centrosomal proteins in a human lymphoblastic cell line. EMBO J. 5, 2545-2550.
13. Guilly, M. N., Danon, F., Brouet, J. C., Bornens, M. and Courvalin, J. C. (1987). Autoantibodies to nuclear lamin B in a patient with thrombopenia. Eur. J. Cell Biol. 43, 266-272.
14. Gundersen, G. G. and Bulinski, J. C. (1986). Distribution of tyrosinated and nontyrosinated alpha-tubulin during mitosis. J. Cell Biol. 102, 1118-1126.
15. Heidemann, S. R. and Gallas, P. T. (1980). The effect of taxol on living eggs of Xenopus laevis. Dev. Biol. 80, 489-494.
16. Hennequin, C., Giocanti, N., Balosso, J. and Favaudon, V. (1994). Interaction of ionizing radiation with the topoisomerase I poison camptothecin in growing V-79 and HeLa cells. Cancer Res. 54, 1720-1728.
17. Hennequin, C., Giocanti, N. and Favaudon, V. (1995). S-phase specificity of cell killing by docetaxel (Taxotere) in synchronised HeLa cells. Br. J. Cancer 71, 1194-1198.
18. Hyman, A. A. and Karsenti, E. (1996). Morphogenetic properties of microtubules and mitotic spindle assembly. Cell 84, 401-410.
19. Jordan, M. A., Toso, R. J., Thrower, D. and Wilson, L. (1993). Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc. Nat. Acad. Sci. USA 90, 9552-9556.
20. Jordan, M. A., Wendell, K., Gardiner, S., Derry, W. B., Copp, H. and Wilson, L. (1996). Mitotic block induced in HeLa cells by low concentrations of Paclitaxel (Taxol) results in abnormal mitosis exit and apoptotic cell death. Cancer Res. 56, 816-825.
21. Kallajoki, M., Weber, K. and Osborn, M. (1992). Ability to organize microtubules in taxol-treated mitotic PtK2 cells goes with the SPN antigen and not with thecentrosome. J. Cell Sci. 102, 91-102.
22. Keryer, G., Ris, H. and Borisy, G. G. (1984). Centriole distribution during tripolar mitosis in Chinese hamster ovary cells. J. Cell Biol. 98, 2222-2229.
23. Kung, A. L., Sherwood, S. W. and Schimke, R. T. (1990). Cell line-specific differences in the control of cell cycle progression in the absence of mitosis. Proc. Nat. Acad. Sci. USA 87, 9553-9557.
24. Kuriyama, R. (1982). Effect of colcemid on the centriole cycle in Chinese hamster ovary cells. J. Cell Sci. 53, 155-171.