Tubulin polymerizing activity of dictyostatin-1, a polyketide of marine sponge origin

Biochemical Pharmacology

Volumn 66, Issue 1, 2003, Pages 75-82

  Isbrucker, Richard A ^a   Cummins, Jennifer ^a   Pomponi, Shirley A ^a   Longley, Ross E ^a,b   Wright, Amy E ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

^b Taxolog Inc   (United States)

Author keywords

Antimitotic; Cytotoxic; Dictyostatin 1; G2 M block; Induction of tubulin polymerization; P glycoprotein efflux pump

Indexed keywords

CYTOTOXIN; DICTYOSTATIN 1; PACLITAXEL; POLYKETIDE; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CATTLE; CELL CYCLE; CELL CYCLE G2 PHASE; COLD; CYTOCHEMISTRY; EFFUSION; HUMAN; HUMAN CELL; MICROTUBULE; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN TRANSPORT; SCREENING; SPONGE (PORIFERA); TEMPERATURE; TOXIN ANALYSIS;

EID: 0038005594     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00192-8     Document Type: Article

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