메뉴 건너뛰기




Volumn 14, Issue 4, 2008, Pages 616-619

Assessing the fraction of short-distance tandem splice sites under purifying selection

Author keywords

Comparative genome analysis; Purifying selection; Simpson's paradox; Subtle alternative splicing; Tandem splice site

Indexed keywords

MESSENGER RNA;

EID: 41649095960     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.883908     Document Type: Article
Times cited : (16)

References (62)
  • 1
    • 12744263064 scopus 로고    scopus 로고
    • Comparison of splice sites in mammals and chicken
    • Abril, J.F., Castelo, R., and Guigo, R. 2005. Comparison of splice sites in mammals and chicken. Genome Res. 15: 111-119.
    • (2005) Genome Res , vol.15 , pp. 111-119
    • Abril, J.F.1    Castelo, R.2    Guigo, R.3
  • 2
    • 31544461505 scopus 로고    scopus 로고
    • Alternative splicing regulation at tandem 3′ splice sites
    • doi: 10.1093/nar/gkj408
    • Akerman, M. and Mandel-Gutfreund, Y. 2006. Alternative splicing regulation at tandem 3′ splice sites. Nucleic Acids Res. 34: 23-31. doi: 10.1093/nar/gkj408.
    • (2006) Nucleic Acids Res , vol.34 , pp. 23-31
    • Akerman, M.1    Mandel-Gutfreund, Y.2
  • 3
    • 24644493193 scopus 로고    scopus 로고
    • Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing
    • Baek, D. and Green, P. 2005. Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing. Proc. Natl. Acad. Sci. 102: 12813-12818.
    • (2005) Proc. Natl. Acad. Sci , vol.102 , pp. 12813-12818
    • Baek, D.1    Green, P.2
  • 6
    • 0016434385 scopus 로고
    • Sex bias in graduate admissions: Data from Berkeley
    • Bickel, P.J., Hammel, E.A., and O'Connell, J.W. 1975. Sex bias in graduate admissions: Data from Berkeley. Science 187: 398-404.
    • (1975) Science , vol.187 , pp. 398-404
    • Bickel, P.J.1    Hammel, E.A.2    O'Connell, J.W.3
  • 7
    • 0013394889 scopus 로고    scopus 로고
    • Mechanisms of alternative pre-messenger RNA splicing
    • Black, D.L. 2003. Mechanisms of alternative pre-messenger RNA splicing. Annu. Rev. Biochem. 72: 291-336.
    • (2003) Annu. Rev. Biochem , vol.72 , pp. 291-336
    • Black, D.L.1
  • 8
    • 0037040282 scopus 로고    scopus 로고
    • Association of the signaling adaptor FRS2 with fibroblast growth factor receptor 1 (Fgfr1) is mediated by alternative splicing of the juxtamembrane domain
    • Burgar, H.R., Burns, H.D., Elsden, J.L., Lalioti, M.D., and Heath, J.K. 2002. Association of the signaling adaptor FRS2 with fibroblast growth factor receptor 1 (Fgfr1) is mediated by alternative splicing of the juxtamembrane domain. J. Biol. Chem. 277: 4018-4023.
    • (2002) J. Biol. Chem , vol.277 , pp. 4018-4023
    • Burgar, H.R.1    Burns, H.D.2    Elsden, J.L.3    Lalioti, M.D.4    Heath, J.K.5
  • 9
    • 33846573830 scopus 로고    scopus 로고
    • Comprehensive analysis of alternative splicing in rice and comparative analyses with Arabidopsis
    • doi: 10.1186/1471-2164-7-327
    • Campbell, M.A., Haas, B.J., Hamilton, J.P., Mount, S.M., and Buell, C.R. 2006. Comprehensive analysis of alternative splicing in rice and comparative analyses with Arabidopsis. BMC Genomics 7: 327. doi: 10.1186/1471-2164-7-327.
    • (2006) BMC Genomics , vol.7 , pp. 327
    • Campbell, M.A.1    Haas, B.J.2    Hamilton, J.P.3    Mount, S.M.4    Buell, C.R.5
  • 11
    • 0037084825 scopus 로고    scopus 로고
    • Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human
    • Clark, F. and Thanaraj, T.A. 2002. Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human. Hum. Mol. Genet. 11: 451-464.
    • (2002) Hum. Mol. Genet , vol.11 , pp. 451-464
    • Clark, F.1    Thanaraj, T.A.2
  • 12
    • 14844363960 scopus 로고    scopus 로고
    • The exon 8-containing prosaposin gene splice variant is dispensable for mouse development, lysosomal function, and secretion
    • Cohen, T., Auerbach, W., Ravid, L., Bodennec, J., Fein, A., Futerman, A.H., Joyner, A.L., and Horowitz, M. 2005. The exon 8-containing prosaposin gene splice variant is dispensable for mouse development, lysosomal function, and secretion. Mol. Cell. Biol. 25: 2431-2440.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 2431-2440
    • Cohen, T.1    Auerbach, W.2    Ravid, L.3    Bodennec, J.4    Fein, A.5    Futerman, A.H.6    Joyner, A.L.7    Horowitz, M.8
  • 13
    • 0028244050 scopus 로고
    • Two alternatively spliced forms of the human insulin-like growth factor I receptor have distinct biological activities and internalization kinetics
    • Condorelli, G., Bueno, R., and Smith, R.J. 1994. Two alternatively spliced forms of the human insulin-like growth factor I receptor have distinct biological activities and internalization kinetics. J. Biol. Chem. 269: 8510-8516.
    • (1994) J. Biol. Chem , vol.269 , pp. 8510-8516
    • Condorelli, G.1    Bueno, R.2    Smith, R.J.3
  • 14
    • 0034194229 scopus 로고    scopus 로고
    • Did nucleotides or amino acids drive evolutionary conservation of the WT1 ± KTS alternative splice?
    • Davies, R.C., Bratt, E., and Hastie, N.D. 2000. Did nucleotides or amino acids drive evolutionary conservation of the WT1 ± KTS alternative splice? Hum. Mol. Genet. 9: 1177-1183.
    • (2000) Hum. Mol. Genet , vol.9 , pp. 1177-1183
    • Davies, R.C.1    Bratt, E.2    Hastie, N.D.3
  • 15
    • 33845248222 scopus 로고    scopus 로고
    • Genomic splice-site analysis reveals frequent alternative splicing close to the dominant splice site
    • Dou, Y., Fox-Walsh, K.L., Baldi, P.F., and Hertel, K.J. 2006. Genomic splice-site analysis reveals frequent alternative splicing close to the dominant splice site. RNA 12: 2047-2056.
    • (2006) RNA , vol.12 , pp. 2047-2056
    • Dou, Y.1    Fox-Walsh, K.L.2    Baldi, P.F.3    Hertel, K.J.4
  • 17
    • 26244435561 scopus 로고    scopus 로고
    • Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures
    • Graveley, B.R. 2005. Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures. Cell 123: 65-73.
    • (2005) Cell , vol.123 , pp. 65-73
    • Graveley, B.R.1
  • 18
    • 0035839099 scopus 로고    scopus 로고
    • Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation
    • Hammes, A., Guo, J.K., Lutsch, G., Leheste, J.R., Landrock, D., Ziegler, U., Gubler, M.C., and Schedl, A. 2001. Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation. Cell 106: 319-329.
    • (2001) Cell , vol.106 , pp. 319-329
    • Hammes, A.1    Guo, J.K.2    Lutsch, G.3    Leheste, J.R.4    Landrock, D.5    Ziegler, U.6    Gubler, M.C.7    Schedl, A.8
  • 19
    • 9644278038 scopus 로고    scopus 로고
    • Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity
    • Hiller, M., Huse, K., Szafranski, K., Jahn, N., Hampe, J., Schreiber, S., Backofen, R., and Platzer, M. 2004. Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity. Nat. Genet. 36: 1255-1257.
    • (2004) Nat. Genet , vol.36 , pp. 1255-1257
    • Hiller, M.1    Huse, K.2    Szafranski, K.3    Jahn, N.4    Hampe, J.5    Schreiber, S.6    Backofen, R.7    Platzer, M.8
  • 20
    • 31544473503 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in NAGNAG acceptors are highly predictive for variations of alternative splicing
    • Hiller, M., Huse, K., Szafranski, K., Jahn, N., Hampe, J., Schreiber, S., Backofen, R., and Platzer, M. 2006a. Single-nucleotide polymorphisms in NAGNAG acceptors are highly predictive for variations of alternative splicing. Am. J. Hum. Genet. 78: 291-302.
    • (2006) Am. J. Hum. Genet , vol.78 , pp. 291-302
    • Hiller, M.1    Huse, K.2    Szafranski, K.3    Jahn, N.4    Hampe, J.5    Schreiber, S.6    Backofen, R.7    Platzer, M.8
  • 22
    • 33751355666 scopus 로고    scopus 로고
    • Alternative splicing at NAGNAG acceptors: Simply noise or noise and more?
    • author reply e208. doi: 10.1371/journal.pgen. 0020207
    • Hiller, M., Szafranski, K., Backofen, R., and Platzer, M. 2006c. Alternative splicing at NAGNAG acceptors: Simply noise or noise and more? PLoS Genet. 2: e207; author reply e208. doi: 10.1371/journal.pgen. 0020207.
    • (2006) PLoS Genet , vol.2
    • Hiller, M.1    Szafranski, K.2    Backofen, R.3    Platzer, M.4
  • 24
    • 0033525863 scopus 로고    scopus 로고
    • 1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition
    • 1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition. J. Biol. Chem. 274: 6754-6762.
    • (1999) J. Biol. Chem , vol.274 , pp. 6754-6762
    • Hu, C.A.1    Lin, W.W.2    Obie, C.3    Valle, D.4
  • 26
    • 0035937805 scopus 로고    scopus 로고
    • γ- Glutamyltransferase and its isoform mediate an endoplasmic reticulum stress response
    • Joyce-Brady, M., Jean, J.C., and Hughey, R.P. 2001. γ- Glutamyltransferase and its isoform mediate an endoplasmic reticulum stress response. J. Biol. Chem. 276: 9468-9477.
    • (2001) J. Biol. Chem , vol.276 , pp. 9468-9477
    • Joyce-Brady, M.1    Jean, J.C.2    Hughey, R.P.3
  • 27
    • 0028020968 scopus 로고
    • Confounding and Simpson's paradox
    • Julious, S.A. and Mullee, M.A. 1994. Confounding and Simpson's paradox. BMJ 309: 1480-1481.
    • (1994) BMJ , vol.309 , pp. 1480-1481
    • Julious, S.A.1    Mullee, M.A.2
  • 31
    • 34247330971 scopus 로고    scopus 로고
    • Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements
    • Lareau, L.F., Inada, M., Green, R.E., Wengrod, J.C., and Brenner, S.E. 2007. Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements. Nature 446: 926-929.
    • (2007) Nature , vol.446 , pp. 926-929
    • Lareau, L.F.1    Inada, M.2    Green, R.E.3    Wengrod, J.C.4    Brenner, S.E.5
  • 32
    • 0037422575 scopus 로고    scopus 로고
    • Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans
    • Lewis, B.P., Green, R.E., and Brenner, S.E. 2003. Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans. Proc. Natl. Acad. Sci. 100: 189-192.
    • (2003) Proc. Natl. Acad. Sci , vol.100 , pp. 189-192
    • Lewis, B.P.1    Green, R.E.2    Brenner, S.E.3
  • 33
    • 33749054403 scopus 로고    scopus 로고
    • Splicing regulation in neurologic disease
    • Licatalosi, D.D. and Darnell, R.B. 2006. Splicing regulation in neurologic disease. Neuron 52: 93-101.
    • (2006) Neuron , vol.52 , pp. 93-101
    • Licatalosi, D.D.1    Darnell, R.B.2
  • 34
    • 10244239317 scopus 로고    scopus 로고
    • Consequences of regulated pre-mRNA splicing in the immune system
    • Lynch, K.W. 2004. Consequences of regulated pre-mRNA splicing in the immune system. Nat. Rev. Immunol. 4: 931-940.
    • (2004) Nat. Rev. Immunol , vol.4 , pp. 931-940
    • Lynch, K.W.1
  • 35
    • 0038617729 scopus 로고    scopus 로고
    • Alternative splicing in the human, mouse, and rat genomes is associated with an increased frequency of exon creation and/or loss
    • Modrek, B. and Lee, C.J. 2003. Alternative splicing in the human, mouse, and rat genomes is associated with an increased frequency of exon creation and/or loss. Nat. Genet. 34: 177-180.
    • (2003) Nat. Genet , vol.34 , pp. 177-180
    • Modrek, B.1    Lee, C.J.2
  • 36
    • 33947305594 scopus 로고    scopus 로고
    • Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay
    • Ni, J.Z., Grate, L., Donohue, J.P., Preston, C., Nobida, N., O'Brien, G., Shiue, L., Clark, T.A., Blume, J.E., and Ares Jr., M. 2007. Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay. Genes & Dev. 21: 708-718.
    • (2007) Genes & Dev , vol.21 , pp. 708-718
    • Ni, J.Z.1    Grate, L.2    Donohue, J.P.3    Preston, C.4    Nobida, N.5    O'Brien, G.6    Shiue, L.7    Clark, T.A.8    Blume, J.E.9    Ares Jr., M.10
  • 37
    • 1942467065 scopus 로고    scopus 로고
    • Genomic variants in exons and introns: Identifying the splicing spoilers
    • Pagani, F. and Baralle, F.E. 2004. Genomic variants in exons and introns: Identifying the splicing spoilers. Nat. Rev. Genet. 5: 389-396.
    • (2004) Nat. Rev. Genet , vol.5 , pp. 389-396
    • Pagani, F.1    Baralle, F.E.2
  • 39
    • 10944245056 scopus 로고    scopus 로고
    • Alternative splicing of conserved exons is frequently species-specific in human and mouse
    • Pan, Q., Bakowski, M.A., Morris, Q., Zhang, W., Frey, B.J., Hughes, T.R., and Blencowe, B.J. 2005. Alternative splicing of conserved exons is frequently species-specific in human and mouse. Trends Genet. 21: 73-77.
    • (2005) Trends Genet , vol.21 , pp. 73-77
    • Pan, Q.1    Bakowski, M.A.2    Morris, Q.3    Zhang, W.4    Frey, B.J.5    Hughes, T.R.6    Blencowe, B.J.7
  • 40
    • 33846914930 scopus 로고    scopus 로고
    • Reduced splicing efficiency induced by synonymous substitutions may generate a substrate for natural selection of new splicing isoforms: The case of CFTR exon 12
    • doi: 10.1093/nar/gkl1087
    • Raponi, M., Baralle, F.E., and Pagani, F. 2007. Reduced splicing efficiency induced by synonymous substitutions may generate a substrate for natural selection of new splicing isoforms: The case of CFTR exon 12. Nucleic Acids Res. 35: 606-613. doi: 10.1093/nar/gkl1087.
    • (2007) Nucleic Acids Res , vol.35 , pp. 606-613
    • Raponi, M.1    Baralle, F.E.2    Pagani, F.3
  • 41
    • 2542603045 scopus 로고    scopus 로고
    • Evidence for a subpopulation of conserved alternative splicing events under selection pressure for protein reading frame preservation
    • doi: 10.1093/nar/gkh284
    • Resch, A., Xing, Y., Alekseyenko, A., Modrek, B., and Lee, C. 2004. Evidence for a subpopulation of conserved alternative splicing events under selection pressure for protein reading frame preservation. Nucleic Acids Res. 32: 1261-1269. doi: 10.1093/nar/gkh284.
    • (2004) Nucleic Acids Res , vol.32 , pp. 1261-1269
    • Resch, A.1    Xing, Y.2    Alekseyenko, A.3    Modrek, B.4    Lee, C.5
  • 43
    • 0001745298 scopus 로고
    • The interpretation of interaction in contingency tables
    • Simpson, E.H. 1951. The interpretation of interaction in contingency tables. J. R. Stat. Soc. [Ser A] 13: 238-241.
    • (1951) J. R. Stat. Soc. [Ser A] , vol.13 , pp. 238-241
    • Simpson, E.H.1
  • 44
    • 0038486897 scopus 로고    scopus 로고
    • Intronic sequences flanking alternatively spliced exons are conserved between human and mouse
    • Sorek, R. and Ast, G. 2003. Intronic sequences flanking alternatively spliced exons are conserved between human and mouse. Genome Res. 13: 1631-1637.
    • (2003) Genome Res , vol.13 , pp. 1631-1637
    • Sorek, R.1    Ast, G.2
  • 45
    • 1642473041 scopus 로고    scopus 로고
    • How prevalent is functional alternative splicing in the human genome?
    • Sorek, R., Shamir, R., and Ast, G. 2004. How prevalent is functional alternative splicing in the human genome? Trends Genet. 20: 68-71.
    • (2004) Trends Genet , vol.20 , pp. 68-71
    • Sorek, R.1    Shamir, R.2    Ast, G.3
  • 46
    • 33751361304 scopus 로고    scopus 로고
    • Inference of splicing regulatory activities by sequence neighborhood analysis
    • doi: 10.1371/journal.pgen.0020191
    • Stadler, M.B., Shomron, N., Yeo, G.W., Schneider, A., Xiao, X., and Burge, C.B. 2006. Inference of splicing regulatory activities by sequence neighborhood analysis. PLoS Genet. 2: e191. doi: 10.1371/journal.pgen.0020191.
    • (2006) PLoS Genet , vol.2
    • Stadler, M.B.1    Shomron, N.2    Yeo, G.W.3    Schneider, A.4    Xiao, X.5    Burge, C.B.6
  • 47
    • 1542359466 scopus 로고    scopus 로고
    • Human tra2-β1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA
    • Stoilov, P., Daoud, R., Nayler, O., and Stamm, S. 2004. Human tra2-β1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA. Hum. Mol. Genet. 13: 509-524.
    • (2004) Hum. Mol. Genet , vol.13 , pp. 509-524
    • Stoilov, P.1    Daoud, R.2    Nayler, O.3    Stamm, S.4
  • 48
    • 2442694425 scopus 로고    scopus 로고
    • Transcriptome and genome conservation of alternative splicing events in humans and mice
    • Sugnet, C.W., Kent, W.J., Ares Jr., M., and Haussler, D. 2004. Transcriptome and genome conservation of alternative splicing events in humans and mice. Pac. Symp. Biocomput. 2004: 66-77.
    • (2004) Pac. Symp. Biocomput , vol.2004 , pp. 66-77
    • Sugnet, C.W.1    Kent, W.J.2    Ares Jr., M.3    Haussler, D.4
  • 49
    • 25444516516 scopus 로고    scopus 로고
    • Frequent occurrence of protein isoforms with or without a single amino acid residue by subtle alternative splicing: The case of Gln in DRPLA affects subcellular localization of the products
    • Tadokoro, K., Yamazaki-Inoue, M., Tachibana, M., Fujishiro, M., Nagao, K., Toyoda, M., Ozaki, M., Ono, M., Miki, N., Miyashita, T., et al. 2005. Frequent occurrence of protein isoforms with or without a single amino acid residue by subtle alternative splicing: The case of Gln in DRPLA affects subcellular localization of the products. J. Hum. Genet. 50: 382-394.
    • (2005) J. Hum. Genet , vol.50 , pp. 382-394
    • Tadokoro, K.1    Yamazaki-Inoue, M.2    Tachibana, M.3    Fujishiro, M.4    Nagao, K.5    Toyoda, M.6    Ozaki, M.7    Ono, M.8    Miki, N.9    Miyashita, T.10
  • 50
    • 0028084768 scopus 로고
    • A novel POU domain gene, zebrafish pou2: Expression and roles of two alternatively spliced twin products in early development
    • Takeda, H., Matsuzaki, T., Oki, T., Miyagawa, T., and Amanuma, H. 1994. A novel POU domain gene, zebrafish pou2: Expression and roles of two alternatively spliced twin products in early development. Genes & Dev. 8: 45-59.
    • (1994) Genes & Dev , vol.8 , pp. 45-59
    • Takeda, H.1    Matsuzaki, T.2    Oki, T.3    Miyagawa, T.4    Amanuma, H.5
  • 53
    • 34547896229 scopus 로고    scopus 로고
    • Wobble splicing reveals the role of the branch point sequence-to-NAGNAG region in 3′ tandem splice site selection
    • Tsai, K.W., Tarn, W.Y., and Lin, W.C. 2007. Wobble splicing reveals the role of the branch point sequence-to-NAGNAG region in 3′ tandem splice site selection. Mol. Cell. Biol. 27: 5835-5848.
    • (2007) Mol. Cell. Biol , vol.27 , pp. 5835-5848
    • Tsai, K.W.1    Tarn, W.Y.2    Lin, W.C.3
  • 55
    • 0037380723 scopus 로고    scopus 로고
    • Comparative genomics: Genome-wide analysis in metazoan eukaryotes
    • Ureta-Vidal, A., Ettwiller, L., and Birney, E. 2003. Comparative genomics: Genome-wide analysis in metazoan eukaryotes. Nat. Rev. Genet. 4: 251-262.
    • (2003) Nat. Rev. Genet , vol.4 , pp. 251-262
    • Ureta-Vidal, A.1    Ettwiller, L.2    Birney, E.3
  • 56
    • 0029860454 scopus 로고    scopus 로고
    • An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity
    • Vogan, K.J., Underhill, D.A., and Gros, P. 1996. An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity. Mol. Cell. Biol. 16: 6677-6686.
    • (1996) Mol. Cell. Biol , vol.16 , pp. 6677-6686
    • Vogan, K.J.1    Underhill, D.A.2    Gros, P.3
  • 57
    • 0033576626 scopus 로고    scopus 로고
    • Functional recognition of the 3′ splice site AG by the splicing factor U2AF35
    • Wu, S., Romfo, C.M., Nilsen, T.W., and Green, M.R. 1999. Functional recognition of the 3′ splice site AG by the splicing factor U2AF35. Nature 402: 832-835.
    • (1999) Nature , vol.402 , pp. 832-835
    • Wu, S.1    Romfo, C.M.2    Nilsen, T.W.3    Green, M.R.4
  • 58
    • 55449137900 scopus 로고    scopus 로고
    • Protein modularity of alternatively spliced exons is associated with tissue-specific regulation of alternative splicing
    • doi: 10.1371/journal.pgen.0010034
    • Xing, Y. and Lee, C.J. 2005. Protein modularity of alternatively spliced exons is associated with tissue-specific regulation of alternative splicing. PLoS Genet. 1: e34. doi: 10.1371/journal.pgen.0010034.
    • (2005) PLoS Genet , vol.1
    • Xing, Y.1    Lee, C.J.2
  • 59
    • 16544392723 scopus 로고    scopus 로고
    • A second protein L-isoaspartyl methyltransferase gene in Arabidopsis produces two transcripts whose products are sequestered in the nucleus
    • Xu, Q., Belcastro, M.P., Villa, S.T., Dinkins, R.D., Clarke, S.G., and Downie, A.B. 2004. A second protein L-isoaspartyl methyltransferase gene in Arabidopsis produces two transcripts whose products are sequestered in the nucleus. Plant Physiol. 136: 2652-2664.
    • (2004) Plant Physiol , vol.136 , pp. 2652-2664
    • Xu, Q.1    Belcastro, M.P.2    Villa, S.T.3    Dinkins, R.D.4    Clarke, S.G.5    Downie, A.B.6
  • 60
    • 0033761628 scopus 로고    scopus 로고
    • Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors
    • Yan, M., Wang, L.C., Hymowitz, S.G., Schilbach, S., Lee, J., Goddard, A., de Vos, A.M., Gao, W.Q., and Dixit, V.M. 2000. Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors. Science 290: 523-527.
    • (2000) Science , vol.290 , pp. 523-527
    • Yan, M.1    Wang, L.C.2    Hymowitz, S.G.3    Schilbach, S.4    Lee, J.5    Goddard, A.6    de Vos, A.M.7    Gao, W.Q.8    Dixit, V.M.9
  • 61
    • 14544277546 scopus 로고    scopus 로고
    • Identification and analysis of alternative splicing events conserved in human and mouse
    • Yeo, G.W., Van Nostrand, E., Holste, D., Poggio, T., and Burge, C.B. 2005. Identification and analysis of alternative splicing events conserved in human and mouse. Proc. Natl. Acad. Sci. 102: 2850-2855.
    • (2005) Proc. Natl. Acad. Sci , vol.102 , pp. 2850-2855
    • Yeo, G.W.1    Van Nostrand, E.2    Holste, D.3    Poggio, T.4    Burge, C.B.5
  • 62
    • 0038349624 scopus 로고    scopus 로고
    • Impact of alternative initiation, splicing, and termination on the diversity of the mRNA transcripts encoded by the mouse transcriptome
    • Zavolan, M., Kondo, S., Schonbach, C., Adachi, J., Hume, D.A., Hayashizaki, Y., and Gaasterland, T. 2003. Impact of alternative initiation, splicing, and termination on the diversity of the mRNA transcripts encoded by the mouse transcriptome. Genome Res. 13: 1290-1300.
    • (2003) Genome Res , vol.13 , pp. 1290-1300
    • Zavolan, M.1    Kondo, S.2    Schonbach, C.3    Adachi, J.4    Hume, D.A.5    Hayashizaki, Y.6    Gaasterland, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.