-
1
-
-
0037422574
-
Crystal structure of saposin B reveals a dimeric shell for lipid binding
-
Ahn, V. E., K. F. Faull, J. P. Whitelegge, A. L. Fluharty, and G. G. Prive. 2003. Crystal structure of saposin B reveals a dimeric shell for lipid binding. Proc. Natl. Acad. Sci. USA 100:38-43.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 38-43
-
-
Ahn, V.E.1
Faull, K.F.2
Whitelegge, J.P.3
Fluharty, A.L.4
Prive, G.G.5
-
2
-
-
0033001385
-
Exposure of human, boar, or bull sperm to a synthetic peptide increases binding to an egg-membrane substrate
-
Amann, R. P., R. H. Hammerstedt, and R. B. Shabanowitz. 1999. Exposure of human, boar, or bull sperm to a synthetic peptide increases binding to an egg-membrane substrate. J. Androl. 20:34-41.
-
(1999)
J. Androl.
, vol.20
, pp. 34-41
-
-
Amann, R.P.1
Hammerstedt, R.H.2
Shabanowitz, R.B.3
-
3
-
-
1842558602
-
Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
-
Arundine, M., and M. Tymianski. 2004. Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cell. Mol. Life Sci. 61:657-668.
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 657-668
-
-
Arundine, M.1
Tymianski, M.2
-
4
-
-
0033801428
-
A procedure for fractionation of sphingolipid classes by solid-phase extraction on aminopropyl cartridges
-
Bodennec, J., O. Koul, I. Aguado, G. Brichon, G. Zwingelstein, and J. Portoukalian. 2000. A procedure for fractionation of sphingolipid classes by solid-phase extraction on aminopropyl cartridges. J. Lipid Res. 41:1524-1531.
-
(2000)
J. Lipid Res.
, vol.41
, pp. 1524-1531
-
-
Bodennec, J.1
Koul, O.2
Aguado, I.3
Brichon, G.4
Zwingelstein, G.5
Portoukalian, J.6
-
6
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
7
-
-
4644296741
-
Conservation of expression and alternative splicing in the prosaposin gene
-
Cohen, T., L. Ravid, N. Altman, L. Madar-Shapiro, A. Fein, M. Weil, and M. Horowitz. 2004. Conservation of expression and alternative splicing in the prosaposin gene. Brain Res. Mol. Brain Res. 129:8-19.
-
(2004)
Brain Res. Mol. Brain Res.
, vol.129
, pp. 8-19
-
-
Cohen, T.1
Ravid, L.2
Altman, N.3
Madar-Shapiro, L.4
Fein, A.5
Weil, M.6
Horowitz, M.7
-
8
-
-
0017599450
-
The activator of cerebroside sulphatase. Binding studies with enzyme and substrate demonstrating the detergent function of the activator protein
-
Fischer, G., and H. Jatzkewitz. 1977. The activator of cerebroside sulphatase. Binding studies with enzyme and substrate demonstrating the detergent function of the activator protein. Biochim. Biophys. Acta 481:561-572.
-
(1977)
Biochim. Biophys. Acta
, vol.481
, pp. 561-572
-
-
Fischer, G.1
Jatzkewitz, H.2
-
9
-
-
70449158340
-
A simple method for the isolation and purification of total lipids from animal tissues
-
Folch, J., M. Lees, and G. H. Sloane Stanley. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226:497-509.
-
(1957)
J. Biol. Chem.
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
10
-
-
0028402219
-
Occurrence of prosaposin as a neuronal surface membrane component
-
Fu, Q., G. S. Carson, M. Hiraiwa, M. Grafe, Y. Kishimoto, and J. S. O'Brien. 1994. Occurrence of prosaposin as a neuronal surface membrane component. J. Mol. Neurosci. 5:59-67.
-
(1994)
J. Mol. Neurosci.
, vol.5
, pp. 59-67
-
-
Fu, Q.1
Carson, G.S.2
Hiraiwa, M.3
Grafe, M.4
Kishimoto, Y.5
O'Brien, J.S.6
-
11
-
-
0029982572
-
Targeted disruption of the mouse sphingolipid activator protein gene: A complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids
-
Fujita, N., K. Suzuki, M. T. Vanier, B. Popko, N. Maeda, A. Klein, M. Henseler, K. Sandhoff, H. Nakayasu, and K. Suzuki. 1996. Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids. Hum. Mol. Genet. 5:711-725.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 711-725
-
-
Fujita, N.1
Suzuki, K.2
Vanier, M.T.3
Popko, B.4
Maeda, N.5
Klein, A.6
Henseler, M.7
Sandhoff, K.8
Nakayasu, H.9
Suzuki, K.10
-
12
-
-
0038350695
-
Structural requirements for lysosomal targeting of the prosaposin precursor protein
-
Ham, D. 2003. Structural requirements for lysosomal targeting of the prosaposin precursor protein. Cell Biol. Int. 27:675-687.
-
(2003)
Cell Biol. Int.
, vol.27
, pp. 675-687
-
-
Ham, D.1
-
13
-
-
0035050467
-
A fragment of prosaposin (SGP-1) from rooster sperm promotes sperm-egg binding and improves fertility in chickens
-
Hammerstedt, R. H., P. G. Cramer, G. F. Barbate, R. P. Amann, J. S. O'Brien, and M. D. Griswold. 2001. A fragment of prosaposin (SGP-1) from rooster sperm promotes sperm-egg binding and improves fertility in chickens. J. Androl. 22:361-375.
-
(2001)
J. Androl.
, vol.22
, pp. 361-375
-
-
Hammerstedt, R.H.1
Cramer, P.G.2
Barbate, G.F.3
Amann, R.P.4
O'Brien, J.S.5
Griswold, M.D.6
-
14
-
-
0029059790
-
Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2
-
Hanks, M., W. Wurst, L. Anson-Cartwright, A. B. Auerbach, and A. L. Joyner. 1995. Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2. Science 269:679-682.
-
(1995)
Science
, vol.269
, pp. 679-682
-
-
Hanks, M.1
Wurst, W.2
Anson-Cartwright, L.3
Auerbach, A.B.4
Joyner, A.L.5
-
15
-
-
0024420051
-
Sphingolipid activator protein deficiency in a 16-week-old atypical Gaucher disease patient and his fetal sibling: Biochemical signs of combined sphingolipidoses
-
Harzer, K., B. C. Paton, A. Poulos, B. Kustermann-Kuhn, W. Roggendorf, T. Grisar, and M. Popp. 1989. Sphingolipid activator protein deficiency in a 16-week-old atypical Gaucher disease patient and his fetal sibling: biochemical signs of combined sphingolipidoses. Eur. J. Pediatr. 149:31-39.
-
(1989)
Eur. J. Pediatr.
, vol.149
, pp. 31-39
-
-
Harzer, K.1
Paton, B.C.2
Poulos, A.3
Kustermann-Kuhn, B.4
Roggendorf, W.5
Grisar, T.6
Popp, M.7
-
16
-
-
0029988339
-
Expression of the three alternative forms of the sphingolipid activator protein precursor in baby hamster kidney cells and functional assays in a cell culture system
-
Henseler, M., A. Klein, G. J. Glombitza, K. Suziki, and K. Sandhoff. 1996. Expression of the three alternative forms of the sphingolipid activator protein precursor in baby hamster kidney cells and functional assays in a cell culture system. J. Biol. Chem. 271:8416-8423.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8416-8423
-
-
Henseler, M.1
Klein, A.2
Glombitza, G.J.3
Suziki, K.4
Sandhoff, K.5
-
17
-
-
0025728991
-
Secretion of sphingolipid hydrolase activator precursor, prosaposin
-
Hineno, T., A. Sano, K. Kondoh, S. Ueno, Y. Kakimoto, and K. Yoshida. 1991. Secretion of sphingolipid hydrolase activator precursor, prosaposin. Biochem. Biophys. Res. Commun. 176:668-674.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.176
, pp. 668-674
-
-
Hineno, T.1
Sano, A.2
Kondoh, K.3
Ueno, S.4
Kakimoto, Y.5
Yoshida, K.6
-
18
-
-
0033152846
-
Prosaposin: A myelinotrophic protein that promotes expression of myelin constituents and is secreted after nerve injury
-
Hiraiwa, M., W. M. Cam pana, A. P. Mizisin, L. Mohiuddin, and J. S. O'Brien. 1999. Prosaposin: a myelinotrophic protein that promotes expression of myelin constituents and is secreted after nerve injury. Glia 26:353-360.
-
(1999)
Glia
, vol.26
, pp. 353-360
-
-
Hiraiwa, M.1
Cam Pana, W.M.2
Mizisin, A.P.3
Mohiuddin, L.4
O'Brien, J.S.5
-
19
-
-
0043023931
-
Regulation of gene expression in response to brain injury: Enhanced expression and alternative splicing of rat prosaposin (SGP-1) mRNA in injured brain
-
Hiraiwa, M., J. Liu, A. G. Lu, C. Y. Wang, R. Misasi, T. Yamauchi, I. Hozumi, T. Inuzuka, and J. S. O'Brien. 2003. Regulation of gene expression in response to brain injury: enhanced expression and alternative splicing of rat prosaposin (SGP-1) mRNA in injured brain. J. Neurotrauma 20:755-765.
-
(2003)
J. Neurotrauma
, vol.20
, pp. 755-765
-
-
Hiraiwa, M.1
Liu, J.2
Lu, A.G.3
Wang, C.Y.4
Misasi, R.5
Yamauchi, T.6
Hozumi, I.7
Inuzuka, T.8
O'Brien, J.S.9
-
20
-
-
0027177509
-
Isolation, characterization, and proteolysis of human prosaposin, the precursor of saposins (sphingolipid activator proteins)
-
Hiraiwa, M., J. S. O'Brien, Y. Kishimoto, M. Galdzicka, A. L. Fluharty, E. I. Ginns, and B. M. Martin. 1993. Isolation, characterization, and proteolysis of human prosaposin, the precursor of saposins (sphingolipid activator proteins). Arch. Biochem. Biophys. 304:110-116.
-
(1993)
Arch. Biochem. Biophys.
, vol.304
, pp. 110-116
-
-
Hiraiwa, M.1
O'Brien, J.S.2
Kishimoto, Y.3
Galdzicka, M.4
Fluharty, A.L.5
Ginns, E.I.6
Martin, B.M.7
-
21
-
-
0026478719
-
Binding and transport of gangliosides by prosaposin
-
Hiraiwa, M., S. Soeda, Y. Kishimoto, and J. S. O'Brien. 1992. Binding and transport of gangliosides by prosaposin. Proc. Natl. Acad. Sci. USA 89:11254-11258.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 11254-11258
-
-
Hiraiwa, M.1
Soeda, S.2
Kishimoto, Y.3
O'Brien, J.S.4
-
22
-
-
0030971534
-
Cell death prevention, mitogen-activated protein kinase stimulation, and increased sulfatide concentrations in Schwann cells and oligodendrocytes by prosaposin and prosaptides
-
Hiraiwa, M., E. M. Taylor, W. M. Campana, S. J. Darin, and J. S. O'Brien. 1997. Cell death prevention, mitogen-activated protein kinase stimulation, and increased sulfatide concentrations in Schwann cells and oligodendrocytes by prosaposin and prosaptides. Proc. Natl. Acad. Sci. USA 94:4778-4781.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4778-4781
-
-
Hiraiwa, M.1
Taylor, E.M.2
Campana, W.M.3
Darin, S.J.4
O'Brien, J.S.5
-
23
-
-
0025743034
-
Sulfatide activator protein. Alternative splicing that generates three mRNAs and a newly found mutation responsible for a clinical disease
-
Holtschmidt, H., K. Sandhoff, H. Y. Kwon, K. Harzer, T. Nakano, and K. Suzuki. 1991. Sulfatide activator protein. Alternative splicing that generates three mRNAs and a newly found mutation responsible for a clinical disease. J. Biol. Chem. 266:7556-7560.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 7556-7560
-
-
Holtschmidt, H.1
Sandhoff, K.2
Kwon, H.Y.3
Harzer, K.4
Nakano, T.5
Suzuki, K.6
-
24
-
-
0033591201
-
Administration of prosaposin ameliorates spatial learning disturbance and reduces cavity formation following stab wounds in rat brain
-
Hozumi, I., M. Hiraiwa, T. Inuzuka, Y. Yoneoka, K. Akiyama, R. Tanaka, K. Kikugawa, R. Nakano, S. Tsuji, and J. S. O'Brien. 1999. Administration of prosaposin ameliorates spatial learning disturbance and reduces cavity formation following stab wounds in rat brain. Neurosci. Lett. 267:73-76.
-
(1999)
Neurosci. Lett.
, vol.267
, pp. 73-76
-
-
Hozumi, I.1
Hiraiwa, M.2
Inuzuka, T.3
Yoneoka, Y.4
Akiyama, K.5
Tanaka, R.6
Kikugawa, K.7
Nakano, R.8
Tsuji, S.9
O'Brien, J.S.10
-
25
-
-
0141540782
-
Kainate receptors and synaptic transmission
-
Huettner, J. E. 2003. Kainate receptors and synaptic transmission. Prog. Neurobiol. 70:387-407.
-
(2003)
Prog. Neurobiol.
, vol.70
, pp. 387-407
-
-
Huettner, J.E.1
-
26
-
-
0035871255
-
A novel mutation in the coding region of the prosaposin gene leads to a complete deficiency of prosaposin and saposins, and is associated with a complex sphingolipidosis dominated by lactosylceramide accumulation
-
Hulkova, H., M. Cervenkova, J. Ledvinova, M. Tochackova, M. Hrebicek, H. Poupetova, A. Befekadu, L. Berna, B. C. Paton, K. Harzer, A. Boor, F. Smid, and M. Elleder. 2001. A novel mutation in the coding region of the prosaposin gene leads to a complete deficiency of prosaposin and saposins, and is associated with a complex sphingolipidosis dominated by lactosylceramide accumulation. Hum. Mol. Genet. 10:927-940.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 927-940
-
-
Hulkova, H.1
Cervenkova, M.2
Ledvinova, J.3
Tochackova, M.4
Hrebicek, M.5
Poupetova, H.6
Befekadu, A.7
Berna, L.8
Paton, B.C.9
Harzer, K.10
Boor, A.11
Smid, F.12
Elleder, M.13
-
27
-
-
0026768211
-
Saposins: Structure, function, distribution, and molecular genetics
-
Kishimoto, Y., M. Hiraiwa, and J. S. O'Brien. 1992. Saposins: structure, function, distribution, and molecular genetics. J. Lipid Res. 33:1255-1267.
-
(1992)
J. Lipid Res.
, vol.33
, pp. 1255-1267
-
-
Kishimoto, Y.1
Hiraiwa, M.2
O'Brien, J.S.3
-
28
-
-
0028275240
-
Sphingolipid activator protein D (Sap-D) stimulates the lysosomal degradation of ceramide in-vivo
-
Klein, A., M. Henseler, C. Klein, K. Suzuki, K. Harzer, and K. Sandhoff. 1994. Sphingolipid activator protein D (Sap-D) stimulates the lysosomal degradation of ceramide in-vivo. Biochem. Biophys. Res. Commun. 200:1440-1448.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.200
, pp. 1440-1448
-
-
Klein, A.1
Henseler, M.2
Klein, C.3
Suzuki, K.4
Harzer, K.5
Sandhoff, K.6
-
29
-
-
0026328108
-
Isolation and characterization of prosaposin from human milk
-
Kondoh, K., T. Hineno, A. Sano, and Y. Kakimoto. 1991. Isolation and characterization of prosaposin from human milk. Biochem. Biophys. Res. Commun. 181:286-292.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.181
, pp. 286-292
-
-
Kondoh, K.1
Hineno, T.2
Sano, A.3
Kakimoto, Y.4
-
30
-
-
0029970341
-
Prosaposin facilitates sciatic nerve regeneration in vivo
-
Kotani, Y., S. Matsuda, M. Sakanaka, K. Kondoh, S. Ueno, and A. Sano. 1996. Prosaposin facilitates sciatic nerve regeneration in vivo. J. Neurochem. 66:2019-2025.
-
(1996)
J. Neurochem.
, vol.66
, pp. 2019-2025
-
-
Kotani, Y.1
Matsuda, S.2
Sakanaka, M.3
Kondoh, K.4
Ueno, S.5
Sano, A.6
-
31
-
-
0025321793
-
Characterization of a mutation in a family with saposin B deficiency: A glycosylation site defect
-
Kretz, K. A., G. S. Carson, S. Morimoto, Y. Kishimoto, A. L. Fluharty, and J. S. O'Brien. 1990. Characterization of a mutation in a family with saposin B deficiency: a glycosylation site defect. Proc. Natl. Acad. Sci. USA 87:2541-2544.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2541-2544
-
-
Kretz, K.A.1
Carson, G.S.2
Morimoto, S.3
Kishimoto, Y.4
Fluharty, A.L.5
O'Brien, J.S.6
-
32
-
-
0027967290
-
Modulation of human saposin B sphingolipid-binding specificity by alternative splicing. A study with saposin B-derived synthetic peptides
-
Lamontagne, S., and M. Potier. 1994. Modulation of human saposin B sphingolipid-binding specificity by alternative splicing. A study with saposin B-derived synthetic peptides. J. Biol. Chem. 269:20528-20532.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 20528-20532
-
-
Lamontagne, S.1
Potier, M.2
-
33
-
-
0030016109
-
Proteolytic processing patterns of prosaposin in insect and mammalian cells
-
Leonova, T., X. Qi, A. Bencosme, E. Ponce, Y. Sun, and G. A. Grabowski. 1996. Proteolytic processing patterns of prosaposin in insect and mammalian cells. J. Biol. Chem. 271:17312-17320.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 17312-17320
-
-
Leonova, T.1
Qi, X.2
Bencosme, A.3
Ponce, E.4
Sun, Y.5
Grabowski, G.A.6
-
34
-
-
0033987611
-
Two Pax2/5/8-binding sites in Engrailed2 are required for proper initiation of endogenous mid-hindbrain expression
-
Li Song, D., and A. L. Joyner. 2000. Two Pax2/5/8-binding sites in Engrailed2 are required for proper initiation of endogenous mid-hindbrain expression. Mech. Dev. 90:155-165.
-
(2000)
Mech. Dev.
, vol.90
, pp. 155-165
-
-
Li Song, D.1
Joyner, A.L.2
-
35
-
-
0033082831
-
Importance of splicing for prosaposin sorting
-
Madar-Shapiro, L., M. Pasmanik-Chor, A. M. Vaccaro, T. Dinur, A. Dagan, S. Gatt, and M. Horowitz. 1999. Importance of splicing for prosaposin sorting. Biochem. J. 337:433-443.
-
(1999)
Biochem. J.
, vol.337
, pp. 433-443
-
-
Madar-Shapiro, L.1
Pasmanik-Chor, M.2
Vaccaro, A.M.3
Dinur, T.4
Dagan, A.5
Gatt, S.6
Horowitz, M.7
-
36
-
-
8444224225
-
Mutation in saposin D domain of sphingolipid activator protein gene causes urinary system defects and cerebellar Purkinje cell degeneration with accumulation of hydroxy fatty acid-containing ceramide in the mouse
-
Matsuda, J., M. Kido, K. Tadano-Aritomi, I. Ishizuka, K. Tominaga, K. Toida, E. Takeda, K. Suzuki, and Y. Kuroda. 2004. Mutation in saposin D domain of sphingolipid activator protein gene causes urinary system defects and cerebellar Purkinje cell degeneration with accumulation of hydroxy fatty acid-containing ceramide in the mouse. Hum. Mol. Genet. 13:2709-2723.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2709-2723
-
-
Matsuda, J.1
Kido, M.2
Tadano-Aritomi, K.3
Ishizuka, I.4
Tominaga, K.5
Toida, K.6
Takeda, E.7
Suzuki, K.8
Kuroda, Y.9
-
37
-
-
0035873272
-
A mutation in the saposin A domain of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse
-
Matsuda, J., M. T. Vanier, Y. Saito, J. Tohyama, and K. Suzuki. 2001. A mutation in the saposin A domain of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse. Hum. Mol. Genet. 10:1191-1199.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1191-1199
-
-
Matsuda, J.1
Vanier, M.T.2
Saito, Y.3
Tohyama, J.4
Suzuki, K.5
-
38
-
-
0030831586
-
Regulation of the secretion and synthesis of rat Sertoli cell SGP-1, SGP-2 and CP-2 by elongate spermatids
-
McKinnell, C., and R. M. Sharpe. 1997. Regulation of the secretion and synthesis of rat Sertoli cell SGP-1, SGP-2 and CP-2 by elongate spermatids. Int. J. Androl. 20:171-179.
-
(1997)
Int. J. Androl.
, vol.20
, pp. 171-179
-
-
McKinnell, C.1
Sharpe, R.M.2
-
39
-
-
0031769454
-
Colocalization and complex formation between prosaposin and monosialoganglioside GM3 in neural cells
-
Misasi, R., M. Sorice, T. Garofalo, T. Griggi, W. M. Campana, M. Giammatteo, A. Pavan, M. Hiraiwa, G. M. Pontieri, and J. S. O'Brien. 1998. Colocalization and complex formation between prosaposin and monosialoganglioside GM3 in neural cells. J. Neurochem. 71:2313-2321.
-
(1998)
J. Neurochem.
, vol.71
, pp. 2313-2321
-
-
Misasi, R.1
Sorice, M.2
Garofalo, T.3
Griggi, T.4
Campana, W.M.5
Giammatteo, M.6
Pavan, A.7
Hiraiwa, M.8
Pontieri, G.M.9
O'Brien, J.S.10
-
40
-
-
0037357780
-
Prosaposin ablation inactivates the MAPK and Akt signaling pathways and interferes with the development of the prostate gland
-
Morales, C. R., and H. Badran. 2003. Prosaposin ablation inactivates the MAPK and Akt signaling pathways and interferes with the development of the prostate gland. Asian J. Androl. 5:57-63.
-
(2003)
Asian J. Androl.
, vol.5
, pp. 57-63
-
-
Morales, C.R.1
Badran, H.2
-
41
-
-
14444269453
-
Distribution of mouse sulfated glycoprotein-1 (prosaposin) in the testis and other tissues
-
Morales, C. R., N. Hay, M. El-Alfy, and Q. Zhao. 1998. Distribution of mouse sulfated glycoprotein-1 (prosaposin) in the testis and other tissues. J. Androl. 19:156-164.
-
(1998)
J. Androl.
, vol.19
, pp. 156-164
-
-
Morales, C.R.1
Hay, N.2
El-Alfy, M.3
Zhao, Q.4
-
42
-
-
0033764584
-
Targeted drsruption of the mouse prosaposin gene affects the development of the prostate gland and other male reproductive organs
-
Morales, C. R., Q. Zhao, M. El-Alfy, and K. Suzuki. 2000. Targeted drsruption of the mouse prosaposin gene affects the development of the prostate gland and other male reproductive organs. J. Androl. 21:765-775.
-
(2000)
J. Androl.
, vol.21
, pp. 765-775
-
-
Morales, C.R.1
Zhao, Q.2
El-Alfy, M.3
Suzuki, K.4
-
43
-
-
0035203559
-
Protective effect of a prosaposin-derived. 18-mer peptide on slowly progressive neuronal degeneration after brief ischemia
-
Morita, F., T. C. Wen, J. Tanaka, R. Hata, J. Desaki, K. Sato, K. Nakata, Y. J. Ma, and M. Sakanaka. 2001. Protective effect of a prosaposin-derived. 18-mer peptide on slowly progressive neuronal degeneration after brief ischemia. J. Cereb. Blood Flow Metab. 21:1295-1302.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 1295-1302
-
-
Morita, F.1
Wen, T.C.2
Tanaka, J.3
Hata, R.4
Desaki, J.5
Sato, K.6
Nakata, K.7
Ma, Y.J.8
Sakanaka, M.9
-
44
-
-
0024593996
-
Structure of full-length cDNA coding for sulfatide activator, a co-beta-glucosidase and two other homologous proteins: Two alternate forms of the sulfatide activator
-
Tokyo
-
Nakano, T., K. Sandhoff, J. Stumper, H. Christomanou, and K. Suzuki. 1989. Structure of full-length cDNA coding for sulfatide activator, a co-beta-glucosidase and two other homologous proteins: two alternate forms of the sulfatide activator. J. Biochem. (Tokyo) 105:152-154.
-
(1989)
J. Biochem.
, vol.105
, pp. 152-154
-
-
Nakano, T.1
Sandhoff, K.2
Stumper, J.3
Christomanou, H.4
Suzuki, K.5
-
45
-
-
0028136476
-
Identification of prosaposin as a neurotrophic factor
-
O'Brien, J. S., G. S. Carson, H. C. Seo, M. Hiraiwa, and Y. Kishimoto. 1994. Identification of prosaposin as a neurotrophic factor. Proc. Natl. Acad. Sci. USA 91:9593-9596.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9593-9596
-
-
O'Brien, J.S.1
Carson, G.S.2
Seo, H.C.3
Hiraiwa, M.4
Kishimoto, Y.5
-
46
-
-
10744231278
-
While K-ras is essential for mouse development, expression of the K-ras 4A splice variant is dispensable
-
Plowman, S. J., D. J. Williamson, M. J. O'Sullivan, J. Doig, A. M. Ritchie, D. J. Harrison, D. W. Melton, M. J. Arends, M. L. Hooper, and C. E. Patek. 2003. While K-ras is essential for mouse development, expression of the K-ras 4A splice variant is dispensable. Mol. Cell. Biol. 23:9245-9250.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 9245-9250
-
-
Plowman, S.J.1
Williamson, D.J.2
O'Sullivan, M.J.3
Doig, J.4
Ritchie, A.M.5
Harrison, D.J.6
Melton, D.W.7
Arends, M.J.8
Hooper, M.L.9
Patek, C.E.10
-
47
-
-
0027192992
-
Mutational analysis in a patient with a variant form of Gaucher disease caused by SAP-2 deficiency
-
Rafi, M. A., G. de Gala, X. L. Zhang, and D. A. Wenger. 1993. Mutational analysis in a patient with a variant form of Gaucher disease caused by SAP-2 deficiency. Somat. Cell Mol. Genet. 19:1-7.
-
(1993)
Somat. Cell Mol. Genet.
, vol.19
, pp. 1-7
-
-
Rafi, M.A.1
De Gala, G.2
Zhang, X.L.3
Wenger, D.A.4
-
48
-
-
0025017535
-
Detection of a point mutation in sphingolipid activator protein-1 mRNA in patients with a variant form of metachromatic leukodystrophy
-
Rafi, M. A., X. L. Zhang, G. DeGala, and D. A. Wenger. 1990. Detection of a point mutation in sphingolipid activator protein-1 mRNA in patients with a variant form of metachromatic leukodystrophy. Biochem. Biophys. Res. Commun. 166:1017-1023.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.166
, pp. 1017-1023
-
-
Rafi, M.A.1
Zhang, X.L.2
DeGala, G.3
Wenger, D.A.4
-
49
-
-
0033061033
-
An Asn > Lys substitution in saposin B involving a conserved amino acidic residue and leading to the loss of the single N-glycosylation site in a patient with metachromatic leukodystrophy and normal arylsulphatase A activity
-
Regis, S., M. Filocamo, F. Corsolini, F. Caroli, J. L. Keulemans, O. P. van Diggelen, and R. Gatti. 1999. An Asn > Lys substitution in saposin B involving a conserved amino acidic residue and leading to the loss of the single N-glycosylation site in a patient with metachromatic leukodystrophy and normal arylsulphatase A activity. Eur. J. Hum. Genet. 7:125-130.
-
(1999)
Eur. J. Hum. Genet.
, vol.7
, pp. 125-130
-
-
Regis, S.1
Filocamo, M.2
Corsolini, F.3
Caroli, F.4
Keulemans, J.L.5
Van Diggelen, O.P.6
Gatti, R.7
-
50
-
-
0035000532
-
Prosaposin is immunolocalized to muscle and prosaptides promote myoblast fusion and attenuate loss of muscle mass after nerve injury
-
Rende, M., E. Brizi, R. Donato, C. Provenzano, R. Bruno, A. P. Mizisin, R. S. Garrett, N. A. Calcutt, W. M. Campana, and J. S. O'Brien. 2001. Prosaposin is immunolocalized to muscle and prosaptides promote myoblast fusion and attenuate loss of muscle mass after nerve injury. Muscle Nerve 24:799-808.
-
(2001)
Muscle Nerve
, vol.24
, pp. 799-808
-
-
Rende, M.1
Brizi, E.2
Donato, R.3
Provenzano, C.4
Bruno, R.5
Mizisin, A.P.6
Garrett, R.S.7
Calcutt, N.A.8
Campana, W.M.9
O'Brien, J.S.10
-
51
-
-
0000956850
-
Sphingolipid activator proteins
-
S. Scriber, A. Beaudet, W. Sly, and D. Valle (ed.), McGraw-Hill, New York, N.Y.
-
Sandhoff, K., K. Harzer, and W. Furst. 1995. Sphingolipid activator proteins, p. 2427-2441. In S. Scriber, A. Beaudet, W. Sly, and D. Valle (ed.), The metabolic and molecular basis of inherited disease, 7th ed. McGraw-Hill, New York, N.Y.
-
(1995)
The Metabolic and Molecular Basis of Inherited Disease, 7th Ed.
, pp. 2427-2441
-
-
Sandhoff, K.1
Harzer, K.2
Furst, W.3
-
53
-
-
0024791636
-
Sphingolipid hydrolase activator proteins and their precursors
-
Sano, A., T. Hineno, T. Mizuno, K. Kondoh, S. Ueno, Y. Kakimoto, and K. Inui. 1989. Sphingolipid hydrolase activator proteins and their precursors. Biochem. Biophys. Res. Commun. 165:1191-1197.
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.165
, pp. 1191-1197
-
-
Sano, A.1
Hineno, T.2
Mizuno, T.3
Kondoh, K.4
Ueno, S.5
Kakimoto, Y.6
Inui, K.7
-
54
-
-
0028043990
-
Protection by prosaposin against ischemia-induced learning disability and neuronal loss
-
Sano, A., S. Matsuda, T. C. Wen, Y. Kotani, K. Kondoh, S. Ueno, Y. Kakimoto, H. Yoshimura, and M. Sakanaka. 1994. Protection by prosaposin against ischemia-induced learning disability and neuronal loss. Biochem. Biophys. Res. Commun. 204:994-1000.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.204
, pp. 994-1000
-
-
Sano, A.1
Matsuda, S.2
Wen, T.C.3
Kotani, Y.4
Kondoh, K.5
Ueno, S.6
Kakimoto, Y.7
Yoshimura, H.8
Sakanaka, M.9
-
55
-
-
20244362501
-
Sphingolipid activator protein 1 deficiency in metachromatic leucodystrophy with normal arylsulphatase A activity. A clinical, morphological, biochemical, and immunological study
-
Schlote, W., K. Harzer, H. Christomanou, B. C. Paton, B. Kustermann-Kuhn, B. Schmid, J. Seeger, U. Beudt, I. Schuster, and U. Langenbeck. 1991. Sphingolipid activator protein 1 deficiency in metachromatic leucodystrophy with normal arylsulphatase A activity. A clinical, morphological, biochemical, and immunological study. Eur. J. Pediatr. 150:584-591.
-
(1991)
Eur. J. Pediatr.
, vol.150
, pp. 584-591
-
-
Schlote, W.1
Harzer, K.2
Christomanou, H.3
Paton, B.C.4
Kustermann-Kuhn, B.5
Schmid, B.6
Seeger, J.7
Beudt, U.8
Schuster, I.9
Langenbeck, U.10
-
56
-
-
0026705846
-
Simultaneous deficiency of sphingolipid activator proteins 1 and 2 is caused by a mutation in the initiation codon of their common gene
-
Schnabel, D., M. Schroder, W. Furst, A. Klein, R. Hurwitz, T. Zenk, J. Weber, K. Harzer, B. C. Paton, A. Poulos, K. Suzuki, and K. Sandhoff. 1992. Simultaneous deficiency of sphingolipid activator proteins 1 and 2 is caused by a mutation in the initiation codon of their common gene. J. Biol. Chem. 267:3312-3315.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 3312-3315
-
-
Schnabel, D.1
Schroder, M.2
Furst, W.3
Klein, A.4
Hurwitz, R.5
Zenk, T.6
Weber, J.7
Harzer, K.8
Paton, B.C.9
Poulos, A.10
Suzuki, K.11
Sandhoff, K.12
-
57
-
-
0025762364
-
Mutation in the sphingolipid activator protein 2 in a patient with a variant of Gaucher disease
-
Schnabel, D., M. Schroder, and K. Sandhoff. 1991. Mutation in the sphingolipid activator protein 2 in a patient with a variant of Gaucher disease. FEBS Lett. 284:57-59.
-
(1991)
FEBS Lett.
, vol.284
, pp. 57-59
-
-
Schnabel, D.1
Schroder, M.2
Sandhoff, K.3
-
58
-
-
0013650617
-
Murine prosaposin: Expression in the reproductive system of a gene implicated in human genetic diseases
-
Sprecher-Levy, H., A. Orr-Urtreger, P. Lonai, and M. Horowitz. 1993. Murine prosaposin: expression in the reproductive system of a gene implicated in human genetic diseases. Cell. Mol. Biol. (Noisy-Le-Grand) 39:287-299.
-
(1993)
Cell. Mol. Biol. (Noisy-Le-Grand)
, vol.39
, pp. 287-299
-
-
Sprecher-Levy, H.1
Orr-Urtreger, A.2
Lonai, P.3
Horowitz, M.4
-
59
-
-
0024822494
-
Sulfated glycoprotein-1 (saposin precursor) in the reproductive tract of the male rat
-
Sylvester, S. R., C. Morales, R. Oko, and M. D. Griswold. 1989. Sulfated glycoprotein-1 (saposin precursor) in the reproductive tract of the male rat. Biol. Reprod. 41:941-948.
-
(1989)
Biol. Reprod.
, vol.41
, pp. 941-948
-
-
Sylvester, S.R.1
Morales, C.2
Oko, R.3
Griswold, M.D.4
-
60
-
-
0032190625
-
Prosaposin prevents programmed cell death of rat cerebellar granule neurons in culture
-
Tsuboi, K., M. Hiraiwa, and J. S. O'Brien. 1998. Prosaposin prevents programmed cell death of rat cerebellar granule neurons in culture. Brain Res. Dev. Brain Res. 110:249-255.
-
(1998)
Brain Res. Dev. Brain Res.
, vol.110
, pp. 249-255
-
-
Tsuboi, K.1
Hiraiwa, M.2
O'Brien, J.S.3
-
61
-
-
33847517624
-
The use of Sephadex for the removal of nonlipid contaminants from lipid extracts
-
Wells, M. A., and J. C. Dittmer. 1963. The use of Sephadex for the removal of nonlipid contaminants from lipid extracts. Biochemistry 172:1259-1263.
-
(1963)
Biochemistry
, vol.172
, pp. 1259-1263
-
-
Wells, M.A.1
Dittmer, J.C.2
-
62
-
-
0030613177
-
Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion
-
White, J. K., W. Auerbach, M. P. Duyao, J. P. Vonsattel, J. F. Gusella, A. L. Joyner, and M. E. MacDonald. 1997. Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion. Nat. Genet. 17:404-410.
-
(1997)
Nat. Genet.
, vol.17
, pp. 404-410
-
-
White, J.K.1
Auerbach, W.2
Duyao, M.P.3
Vonsattel, J.P.4
Gusella, J.F.5
Joyner, A.L.6
MacDonald, M.E.7
-
63
-
-
0033971433
-
A non-glycosylated and functionally deficient mutant (N215H) of the sphingolipid activator protein B (SAP-B) in a novel case of metachromatic leukodystrophy (MLD)
-
Wrobe, D., M. Henseler, S. Huettler, S. I. Pascual Pascual, A. Chabas, and K. Sandhoff. 2000. A non-glycosylated and functionally deficient mutant (N215H) of the sphingolipid activator protein B (SAP-B) in a novel case of metachromatic leukodystrophy (MLD). J. Inherit. Metab. Dis. 23:63-76.
-
(2000)
J. Inherit. Metab. Dis.
, vol.23
, pp. 63-76
-
-
Wrobe, D.1
Henseler, M.2
Huettler, S.3
Pascual Pascual, S.I.4
Chabas, A.5
Sandhoff, K.6
-
64
-
-
0002429430
-
Production of targeted embryonic stem cell clones
-
A. L. Joyner (ed.), IRL Press, Oxford, United Kingdom
-
Wurst, W., and A. L. Joyner. 1993. Production of targeted embryonic stem cell clones, p. 33-61. In A. L. Joyner (ed.), Gene targeting: a practical approach. IRL Press, Oxford, United Kingdom.
-
(1993)
Gene Targeting: A Practical Approach
, pp. 33-61
-
-
Wurst, W.1
Joyner, A.L.2
-
65
-
-
0017759258
-
Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle
-
Yaffe, D., and O. Saxel. 1977. Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle. Nature 270:725-727.
-
(1977)
Nature
, vol.270
, pp. 725-727
-
-
Yaffe, D.1
Saxel, O.2
-
66
-
-
3042841585
-
Comparative clinico-pathological study of saposin-A-deficient (SAP-A-/-) and Twitcher mice
-
Yagi, T., J. Matsuda, S. Takikita, I. Mohri, and K. Suzuki. 2004. Comparative clinico-pathological study of saposin-A-deficient (SAP-A-/-) and Twitcher mice. J. Neuropathol. Exp. Neurol. 63:721-734.
-
(2004)
J. Neuropathol. Exp. Neurol.
, vol.63
, pp. 721-734
-
-
Yagi, T.1
Matsuda, J.2
Takikita, S.3
Mohri, I.4
Suzuki, K.5
-
67
-
-
0025908730
-
The mechanism for a 33-nucleotide insertion in mRNA causing sphingolipid activator protein (SAP-1)-deficient metachromatic leukodystrophy
-
Zhang, X. L., M. A. Rafi, G. DeGala, and D. A. Wenger. 1991. The mechanism for a 33-nucleotide insertion in mRNA causing sphingolipid activator protein (SAP-1)-deficient metachromatic leukodystrophy. Hum. Genet. 87:211-215.
-
(1991)
Hum. Genet.
, vol.87
, pp. 211-215
-
-
Zhang, X.L.1
Rafi, M.A.2
DeGala, G.3
Wenger, D.A.4
-
68
-
-
0030745853
-
Structural analysis of the mouse prosaposin (SGP-1) gene reveals the presence of an exon that is alternatively spliced in transcribed mRNAs
-
Zhao, Q., N. Hay, and C. R. Morales. 1997. Structural analysis of the mouse prosaposin (SGP-1) gene reveals the presence of an exon that is alternatively spliced in transcribed mRNAs. Mol. Reprod. Dev. 48:1-8.
-
(1997)
Mol. Reprod. Dev.
, vol.48
, pp. 1-8
-
-
Zhao, Q.1
Hay, N.2
Morales, C.R.3
|