Reduced splicing efficiency induced by synonymous substitutions may generate a substrate for natural selection of new splicing isoforms: The case of CFTR exon 12

Nucleic Acids Research

Volumn 35, Issue 2, 2007, Pages 606-613

  Raponi, Michela ^a   Baralle, Francisco E ^a   Pagani, Franco ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

AMINO ACID SUBSTITUTION; ARTICLE; COMPUTER MODEL; COMPUTER PREDICTION; COMPUTER PROGRAM; EXON; GENE MUTATION; GENETIC VARIABILITY; HUMAN; MOLECULAR EVOLUTION; NATURAL SELECTION; PRIORITY JOURNAL; RNA SPLICING; SITE DIRECTED MUTAGENESIS;

ALTERNATIVE SPLICING; BASE SEQUENCE; CELL LINE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EVOLUTION, MOLECULAR; EXONS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN ISOFORMS; SELECTION (GENETICS);

PRIMATES;

EID: 33846914930     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl1087     Document Type: Article

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