Lipopolysaccharide sensing an important factor in the innate immune response to Gram-negative bacterial infections: Benefits and hazards of LPS hypersensitivity

Immunobiology

Volumn 213, Issue 3-4, 2008, Pages 193-203

  Freudenberg, Marina A ^a   Tchaptchet, Sandrine ^a   Keck, Simone ^a,b   Fejer, György ^a   Huber, Michael ^b   Schütze, Nicole ^c   Beutler, Bruce ^d   Galanos, Chris ^a  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c Faculty of Veterinary Medicine   (Germany)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Bacterial infections; Interferons; Lipopolysaccharide; LPS hypersensitivity; TLR; TLR ligands; Viral infections

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; LIGAND; MYELOID DIFFERENTIATION PROTEIN 2; PROTEIN; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

BACTERIAL INFECTION; GRAM NEGATIVE INFECTION; HUMAN; HYPERSENSITIVITY; IMMUNOREACTIVITY; INNATE IMMUNITY; LISTERIA MONOCYTOGENES; NONHUMAN; PRIORITY JOURNAL; REVIEW; SALMONELLA TYPHIMURIUM; SIGNAL TRANSDUCTION; SUPERINFECTION; TRANSGENIC MOUSE; VIRUS INFECTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; IMMUNE SYSTEM; INTERFERON TYPE II; INTERLEUKIN-12; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 41649093814     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2007.11.008     Document Type: Review

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