T cell-dependent activation of dendritic cells requires IL-12 and IFN-γ signaling in T cells

Journal of Immunology

Volumn 177, Issue 6, 2006, Pages 3625-3634

  Miro, Francesc ^a   Nobile, Cinzia ^a   Blanchard, Nicolas ^a   Lind, Marianne ^a   Filipe Santos, Orchidée ^b   Fieschi, Claire ^b   Chapgler, Ariane ^b   Vogt, Guillaume ^b   De Beaucoudrey, Ludovic ^b   Kumararatne, Dinakantha S ^c   Le Deist, Françoise ^d   Casanova, Jean Laurent ^b   Amigorena, Sebastian ^a   Hivroz, Claire ^a  

^a INSERM   (France)

^b IMAGINE INSTITUTE   (France)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INTERFERON GAMMA RECEPTOR 1; INTERFERON GAMMA RECEPTOR 2; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; GENETIC DISORDER; HUMAN; HUMAN CELL; IMMUNITY; MYCOBACTERIOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 33748479267     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.6.3625     Document Type: Article

References (44)

1. Dorman, S. E., C. Picard, D. Lammas, K. Heyne, J. T. van Dissel, R. Baretto, S. D. Rosenzweig, M. Newport, M. Levin, J. Roesler, et al. 2004. Clinical features of dominant and recessive interferon γ receptor 1 deficiencies. Lancet 364: 2113-2121.
2. Reichenbach, J., S. Rosenzweig, R. Doffinger, S. Dupuis, S. M. Holland, and J. L. Casanova. 2001. Mycobacterial diseases in primary immunodeficiencies. Curr. Opin. Allergy Clin. Immunol. 1: 503-511.
3. Casanova, J. L., and L. Abel. 2002. Genetic dissection of immunity to mycobacteria: the human model. Annu. Rev. Immunol. 20: 581-620.
4. DiSanto, J. P., J. Y. Bonnefoy, J. F. Gauchat, A. Fischer, and G. de Saint Basileqq. 1993. CD40 ligand mutations in x-linked immunodeficiency with hyper-IgM. Nature 361: 541-543.
5. Korthauer, U., D. Graf, H. W. Mages, F. Briere, M. Padayachee, S. Malcolm, A. G. Ugazio, L. D. Notarangelo, R. J. Levinsky, and R. A. Kroczek. 1993. Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM. Nature 361: 539-541.
6. Levy, J., T. Espanol-Boren, C. Thomas, A. Fischer, P. Tovo, P. Bordigoni, I. Resnick, A. Fasth, M. Baer, L. Gomez, et al. 1997. Clinical spectrum of X-linked hyper-IgM syndrome. J. Pediatr. 131: 47-54.
7. Alcais, A., C. Fieschi, L. Abel, and J. L. Casanova. 2005. Tuberculosis in children and adults: two distinct genetic diseases. J. Exp. Med. 202: 1617-1621.
8. + T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming. Proc. Natl. Acad. Sci. USA 90: 10188-10192.
9. + T cells through IL-12 produced by Listeria-induced macrophages. Science 260: 547-549.
10. Trinchieri, G. 2003. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev. Immunol. 3: 133-146.
11. Steinman, R. M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9: 271-296.
12. Reis e Sousa, C. 2001. Dendritic cells as sensors of infection. Immunity 14: 495-498.
13. Behrens, G., M. Li, C. M. Smith, G. T. Belz, J. Mintern, F. R. Carbone, and W. R. Heath. 2004. Helper T cells, dendritic cells and CTL immunity. Immunol. Cell Biol. 82: 84-90.
14. De Jong, E. C., H. H. Smits, and M. L. Kapsenberg. 2005. Dendritic cell-mediated T cell polarization. Springer Semin. Immunopathol. 26: 289-307.
15. Bennett, S. R., F. R. Carbone, F. Karamalis, R. A. Flavell, J. F. Miller, and W. R. Heath. 1998. Help for cytotoxic-T-cell responses is mediated by CD40 signalling. Nature 393: 478-480.
16. Schoenberger, S. P., R. E. Toes, E. I. van der Voort, R. Offringa, and C. J. Melief. 1998. T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 393: 480-483.
17. + T-helper and a T-killer cell. Nature 393: 474-478.
18. + cytotoxic T lymphocytes. J. Exp. Med. 191: 541-550.
19. Caux, C., C. Massacrier, B. Vanbervliet, B. Dubois, C. Van Kooten, I. Durand, and J. Banchereau. 1994. Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 180: 1263-1272.
20. + hematopoietic progenitors induces their proliferation and differentiation into functional dendritic cells. J Exp. Med. 185: 341-349.
21. Cella, M., D. Scheidegger, K. Palmer-Lehmann, P. Lane, A. Lanzavecchia, and G. Alber. 1996. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 184: 747-752.
22. Snijders, A., P. Kalinski, C. M. Hilkens, and M. L. Kapsenberg. 1998. High-level IL-12 production by human dendritic cells requires two signals. Int. Immunol. 10: 1593-1598.
23. + T cells. Nat. Immunol. 2: 1010-1017.
24. Vogt, G., A. Chapgier, K. Yang, N. Chuzhanova, J. Feinberg, C. Fieschi, S. Boisson-Dupuis, A. Alcais, O. Filipe-Santos, J. Bustamante, et al. 2005. Gains of glycosylation comprise an unexpectedly large group of pathogenic mutations. Nat. Genet. 37: 692-700.
25. Altare, F., D. Lammas, P. Revy, E. Jouanguy, R. Doffinger, S. Lamhamedi, P. Drysdale, D. Scheel-Toellner, J. Girdlestone, P. Darbyshire, et al. 1998. Inherited interleukin 12 deficiency in a child with bacille Calmette-Guerin and Salmonella enteritidis disseminated infection. J. Clin. Invest. 102: 2035-2040.
26. Fieschi, C., S. Dupuis, E. Catherinot, J. Feinberg, J. Bustamante, A. Breiman, F. Altare, R. Baretto, F. Le Deist, S. Kayal, et al. 2003. Low penetrance, broad resistance, and favorable outcome of interleukin 12 receptor β1 deficiency: medical and immunological implications. J. Exp. Med. 197: 527-535.
27. + T cells. J. Immunol. 173: 3062-3072.
28. Sallusto, F., D. Lenig, R. Forster, M. Lipp, and A. Lanzavecchia. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401: 708-712.
29. Pestka, S., S. V. Kotenko, G. Muthukumaran, L. S. Izotova, J. R. Cook, and G. Garotta. 1997. The interferon γ (IFN-γ) receptor: a paradigm for the multichain cytokine receptor. Cytokine Growth Factor Rev. 8: 189-206.
30. + T cell populations lacking helper function. Nat. Immunol. 6: 163-170.
31. Schulz, O., A. D. Edwards, M. Schito, J. Aliberti, S. Manickasingham, A. Sher, and C. Reis e Sousa. 2000. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity 13: 453-462.
32. Sporri, R., and C. Reis e Sousa. 2003. Newly activated T cells promote maturation of bystander dendritic cells but not IL-12 production. J. Immunol. 171: 6406-6413.
33. Shortman, K., and Y. J. Liu. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2: 151-161.
34. Dorman, S. E., and S. M. Holland. 1998. Mutation in the signal-transducing chain of the interferon-γ receptor and susceptibility to mycobacterial infection. J. Clin. Invest. 101: 2364-2369.
35. Losana, G., L. Rigamonti, I. Borghi, B. Assenzio, S. Ariotti, E. Jouanguy, F. Altare, G. Forni, J. L. Casanova, and F. Novelli. 2002. Requirement for both IL-12 and IFN-γ signaling pathways in optimal IFN-γ production by human T cells. Eur. J. Immunol. 32: 693-700.
36. Feinberg, J., C. Fieschi, R. Doffinger, M. Feinberg, T. Leclerc, S. Boisson-Dupuis, C. Picard, J. Bustamante, A. Chapgier, O. Filipe-Santos, et al. 2004. Bacillus Calmette Guerin triggers the IL-12/IFN-γ axis by an IRAK-4- and NEMO-dependent, non-cognate interaction between monocytes, NK, and T lymphocytes. Eur. J. Immunol. 34: 3276-3284.
37. Flesch, I. E., J. H. Hess, S. Huang, M. Aguet, J. Rothe, H. Bluethmann, and S. H. Kaufmann. 1995. Early interleukin 12 production by macrophages in response to mycobacterial infection depends on Interferon γ and tumor necrosis factor α. J. Exp. Med. 181: 1615-1621.
38. Rogge, L., D. D'Ambrosio, M. Biffi, G. Penna, L. J. Minetti, D. H. Presky, L. Adorini, and F. Sinigaglia. 1998. The role of Stat4 in species-specific regulation of Th cell development by type I IFNs. J. Immunol. 161: 6567-6574.
39. Borg, C., A. Jalil, D. Laderach, K. Maruyama, H. Wakasugi, S. Charrier, B. Ryffel, A. Cambi, C. Figdor, W. Vainchenker, et al. 2004. NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs. Blood 104: 3267-3275.
40. Taieb, J., N. Chaput, C. Menard, L. Apetoh, E. Ullrich, M. Bonmort, M. Pequignot, N. Casares, M. Terme, C. Flament, et al. 2006. A novel dendritic cell subset involved in tumor immunosurveillance. Nat. Med. 12: 214-219.
41. + T cells. Nat. Immunol. 3: 549-557.
42. Blanchard, N., V. Di Bartolo, and C. Hivroz. 2002. In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern. Immunity 17: 389-399.
43. Boisvert, J., S. Edmondson, and M. F. Krummel. 2004. Immunological synapse formation licenses CD40-CD40L accumulations at T-APC contact sites. J. Immunol. 173: 3647-3652.
44. Maldonado, R. A., D. J. Irvine, R. Schreiber, and L. H. Glimcher. 2004. A role for the immunological synapse in lineage commitment of CD4 lymphocytes. Nature 431: 527-532.