Sporadic breast cancers exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden disease locus

Genes Chromosomes and Cancer

Volumn 21, Issue 2, 1998, Pages 166-171

  Singh, Baljit ^a   Ittmann, Michael M ^b,c   Krolewski, John J ^a  

^a College of Physicians and Surgeons ^*  (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ADULT; AGED; ALLELE; ARTICLE; AUTORADIOGRAPHY; BREAST CANCER; CANCER SUSCEPTIBILITY; CHROMOSOME 10Q; CHROMOSOME DELETION; CLINICAL ARTICLE; CONTROLLED STUDY; COWDEN SYNDROME; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROGNOSIS; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA, MUCINOUS; ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CHROMOSOMES, HUMAN, PAIR 10; HAMARTOMA SYNDROME, MULTIPLE; HUMANS; LOSS OF HETEROZYGOSITY; MIDDLE AGED;

EID: 0031916211     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199802)21:2<166::AID-GCC13>3.0.CO;2-P     Document Type: Article

References (25)

1. Berx G, Cleton-Jansen A-M, Nollet F, de Leeuw WJF, van de Vijver MJ, Cornelisse C, van Roy F (1995) E-cadherin is a tumor/invasion suppressor gene mutated in human lobular breast cancers. EMBO J 14:6107-6115.
2. Berx G, Cleton-Jansen A-M, Strumane K, de Leeuw W, Nollet F, van Roy F, Cornelisse C (1996) E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene 13:1919-1925.
3. Bièche I, Lidereau R (1995) Genetic alterations in breast cancer. Genes Chromosomes Cancer 14:227-251.
4. Devilee P, Cornelisse CJ (1994) Somatic genetic changes in human breast cancer. Biochim Biophys Acta 1198:113-130.
5. Eeles RA, Bartkova J, Lane DP, Bartek J (1993) The role of TP53 in breast cancer development. Cancer Surv 18:57-75.
6. Gray IC, Phillips SMA, Lee SJ, Neoptolemos JP, Weissenbach J, Spurr NK (1995) Loss of the chromosomal region 10q23-25 in prostate cancer. Cancer Res 55:4800-4803.
7. Healy E, Belgaid CE, Takata M, Vahlquist A, Rehman I, Rigby H, Rees JL (1996) Allelotypes of primary cutaneous melanoma and benign melanocytic nevi. Cancer Res 56:589-593.
8. Hudson TJ, Stein LD, Gerety SS, Ma J, Castle AB, Silva J, Slonim DK, Baptista R, Kruglyak L, Xu S-H, Hu X, Colbert AME, Rosenberg C, Reeve-Daly MP, Rozen S, Hui L, Wu X, Vestergaard C, Wilson KM, Bae JS, Maitra S, Ganiatsas S, Evans CA, DeAngelis MM, Ingalls KA, Nahf RW, Horton LT, Anderson MO, Collymore AL, Ye W, Kouyoumijian V, Zemsteva IS, Tam J, Devine R, Courtney DF, Renaud MT, Nguyen H, O'Connor TJ, Fizames C, Faure S, Gyapay G, Dib C, Morissette J, Otlin JB, Birren BW, Goodman N, Weissenbach J, Hawkins TL, Foote S, Page DC, Lander ES (1995) An STS-based map of the human genome. Science 270:1945-1954.
9. Huntsberger DV, Leaverton PE (1970) Statistical Inference in the Biological Sciences. Boston: Allyn & Bacon.
10. Ittmann M (1996a) Allelic loss of chromosome 10 in prostate adenocarcinoma. Cancer Res 56:2143-2147.
11. Ittmann MM (1996b) Loss of heterozygosity on chromosomes 10 and 17 in clinically localized prostate carcinoma. Prostate 28:275-281.
12. Kerangueven F, Eisinger F, Noguchi T, Allione F, Wargniez V, Eng C, Padberg G, Theillet C, Jacquenier J, Longy M, Sobol H, Birnbaum D (1997) Loss of heterozygosity in human breast carcinoma in the ataxia telangiectasia, Cowden disease and BRCA1 gene regions. Oncogene 14:339-347.
13. Knudsen AG (1993) Antioncogenes and cancer. Proc Natl Acad Sci USA 90:10914-10921.
14. Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang S, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R (1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275:1943-1947.
15. Liaw D, Marsh DJ, Li J, Dahia PLM, Wang SI, Zheng Z, Bose S, Call KM, Tsou HC, Peacocke M, Eng C, Parsons R (1997) Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 16:64-67.
16. MacGrogan D, Levy A, Bostwick D, Wagner M, Wells D, Bookstein R (1994) Loss of chromosome arm 8p loci in prostate cancer: Mapping by quantitative allelic imbalance. Genes Chromosomes Cancer 10:151-159.
17. Nelen MR, Padberg GW, Peeters EAJ, Lin AY, van den Helm B, Frants RR, Coulon V, Goldstein AM, van Reen MMM, Easton DF, Eeles RA, Hodgson S, Mulvihill JJ, Murday VA, Tucker MA, Mariman ECM, Starink TM, Ponder BAJ, Ropers HH, Kremer H, Longy M, Eng C (1996) Localization of the gene for Cowden disease to chromosome 10q22-23. Nat Genet 13:114-116.
18. Peiffer SL, Herzog TJ, Tribune DJ, Mutch DG, Gersell DJ, Goodfellow PJ (1995) Allelic loss of sequences from the long arm of chromosome 10 and replication errors in endometrial cancers. Cancer Res 55:1922-1926.
19. Petersen I, Langreck H, Wolf G, Schwandel A, Psille R, Vogt P, Reichel MB, Ried T, Dietel M (1997) Small-cell lung cancer is characterized by a high incidence of deletions on chromosomes 3p, 4q, 5q, 10q, 13q and 17p. Br J Cancer 75:79-86.
20. Rasheed BKA, McLendon RE, Friedman HS, Friedman AH, Fuchs HE, Bigner DD, Bigner SH (1995) Chromosome 10 deletion mapping in human gliomas: A common deletion region in 10q25. Oncogene 10:2243-2246.
21. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
22. Simon M, Kokkino AJ, Warnick RE, Tew JM, von Deimling A, Menon AG (1996) Role of genomic instability in meningioma progression. Genes Chromosomes Cancer 16:265-269.
23. Starink TM, van der Veen JPW, Arwert F, de Waal LP, de Lange GG, Gille JJP, Eriksson AW (1986) The Cowden syndrome: A clinical and genetic study in 21 patients. Clin Genet 29:222-233.
24. Steck PA, Perhouse MA, Jasser SA, Yung WKA, Lin H, Ligon AH, Langford LA, Baumgard ML, Hattier T, Davis T, Frye C, Hu R, Swedlund B, Teng DHF, Tavtigian SV (1997) Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.2 that is mutated in multiple advanced cancers. Nat Genet 15:356-362.
25. Trybus T, Burgess A, Wojno K, Glover T, Macoska J (1996) Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer. Cancer Res 56:2263-2267.