메뉴 건너뛰기




Volumn 61, Issue 15, 2004, Pages 1896-1906

The role of apolipoprotein E in lipid metabolism in the central nervous system

Author keywords

Alzheimer's disease; Apolipoprotein E; Cholesterol; Electrospray ionization mass spectrometry; Lipidomics; Phospholipids; Sulfatide

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; PHOSPHOLIPID; POLYUNSATURATED FATTY ACID; SULFATIDE;

EID: 4143115606     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-004-4009-z     Document Type: Review
Times cited : (57)

References (123)
  • 1
    • 0000001577 scopus 로고
    • Lipoprotein separation and analysis for clinical studies
    • Converse C. A. and Skinner E. R. (eds), Oxford University Press, New York
    • Mackness M. I. and Durrington P. N. (1992) Lipoprotein separation and analysis for clinical studies. In: Lipoprotein Analysis: A Practical Approach, pp. 1-42, Converse C. A. and Skinner E. R. (eds), Oxford University Press, New York
    • (1992) Lipoprotein Analysis: A Practical Approach , pp. 1-42
    • Mackness, M.I.1    Durrington, P.N.2
  • 2
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown M. S. and Goldstein J. L. (1986) A receptor-mediated pathway for cholesterol homeostasis. Science 232: 34-47
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 3
    • 0037713342 scopus 로고    scopus 로고
    • Reverse cholesterol transport, high density lipoproteins and HDL cholesterol: Recent data
    • Fredenrich A. and Bayer P. (2003) Reverse cholesterol transport, high density lipoproteins and HDL cholesterol: recent data. Diabetes Metab. 29: 201-205
    • (2003) Diabetes Metab. , vol.29 , pp. 201-205
    • Fredenrich, A.1    Bayer, P.2
  • 4
    • 0141500234 scopus 로고    scopus 로고
    • Regulation of reverse cholesterol transport and clinical implications
    • Rader D. J. (2003) Regulation of reverse cholesterol transport and clinical implications. Am. J. Cardiol. 92: 42J-49J
    • (2003) Am. J. Cardiol. , vol.92
    • Rader, D.J.1
  • 5
    • 0742321817 scopus 로고    scopus 로고
    • HDL: The metabolism, function and therapeutic importance
    • Wang M. and Briggs M. R. (2004) HDL: The metabolism, function and therapeutic importance. Chem. Rev. 104: 119-137
    • (2004) Chem. Rev. , vol.104 , pp. 119-137
    • Wang, M.1    Briggs, M.R.2
  • 8
    • 0027374047 scopus 로고
    • Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions
    • Rebeck G. W., Reiter J. S., Strickland D. K. and Hyman B. T. (1993) Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron 11: 575-580
    • (1993) Neuron , vol.11 , pp. 575-580
    • Rebeck, G.W.1    Reiter, J.S.2    Strickland, D.K.3    Hyman, B.T.4
  • 9
    • 0023943675 scopus 로고
    • The apolipoprotein multigene family: Biosynthesis, structure, structure-function relationships and evolution
    • Li W. H., Tanimura M., Luo C. C., Datta S. and Chan L. (1988) The apolipoprotein multigene family: biosynthesis, structure, structure-function relationships and evolution. J. Lipid Res. 29: 245-271
    • (1988) J. Lipid Res. , vol.29 , pp. 245-271
    • Li, W.H.1    Tanimura, M.2    Luo, C.C.3    Datta, S.4    Chan, L.5
  • 11
    • 0027987314 scopus 로고
    • Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels
    • de Knijff P., van den Maagdenberg A. M. J. M., Frants R. R. and Havekes L. M. (1994) Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels. Hum. Mutat. 4: 178-194
    • (1994) Hum. Mutat. , vol.4 , pp. 178-194
    • De Knijff, P.1    Van Den Maagdenberg, A.M.J.M.2    Frants, R.R.3    Havekes, L.M.4
  • 13
    • 0037345672 scopus 로고    scopus 로고
    • Expanding the association between the APOE gene and the risk of Alzheimer's disease: Possible roles for APOE promoter polymorphisms and alterations in APOE transcription
    • Laws S. M., Hone E., Gandy S. and Martins R. N. (2003) Expanding the association between the APOE gene and the risk of Alzheimer's disease: possible roles for APOE promoter polymorphisms and alterations in APOE transcription. J. Neurochem. 84: 1215-1236
    • (2003) J. Neurochem. , vol.84 , pp. 1215-1236
    • Laws, S.M.1    Hone, E.2    Gandy, S.3    Martins, R.N.4
  • 14
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • Mahley R. W. (1988) Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology. Science 240: 622-630
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 15
    • 0036598957 scopus 로고    scopus 로고
    • Apolipoproteins and aging: Emerging mechanisms
    • Smith J. (2002) Apolipoproteins and aging: emerging mechanisms. Ageing Res. Rev. 1: 345-365
    • (2002) Ageing Res. Rev. , vol.1 , pp. 345-365
    • Smith, J.1
  • 16
    • 0022978831 scopus 로고
    • Immunoreactive apolipoprotein E is a widely distributed cellular protein. Immunohistochemical localization of apolipoprotein E in baboon tissues
    • Lin C. T., Xu Y., Wu J. Y. and Chan L. (1986) Immunoreactive apolipoprotein E is a widely distributed cellular protein. Immunohistochemical localization of apolipoprotein E in baboon tissues. J. Clin. Invest. 78: 947-958
    • (1986) J. Clin. Invest. , vol.78 , pp. 947-958
    • Lin, C.T.1    Xu, Y.2    Wu, J.Y.3    Chan, L.4
  • 17
    • 0004982358 scopus 로고
    • Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets
    • Elshourbagy N. A., Liao W. S., Mahley R. W. and Taylor J. M. (1985) Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets. Proc. Natl. Acad. Sci. USA 82: 203-207
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 203-207
    • Elshourbagy, N.A.1    Liao, W.S.2    Mahley, R.W.3    Taylor, J.M.4
  • 18
    • 0029796198 scopus 로고    scopus 로고
    • Apolipoprotein E gene expression in various tissues of mouse and regulation by estrogen
    • Srivastava R. A. K., Bhasin N. and Srivastava N. (1996) Apolipoprotein E gene expression in various tissues of mouse and regulation by estrogen. Biochem. Mol. Biol. Int. 38: 91-101
    • (1996) Biochem. Mol. Biol. Int. , vol.38 , pp. 91-101
    • Srivastava, R.A.K.1    Bhasin, N.2    Srivastava, N.3
  • 19
    • 0018701795 scopus 로고
    • Altered metabolism (in vivo and in vitro) of plasma lipoproteins after selective chemical modification of lysine residues of the apoproteins
    • Mahley R. W., Innerarity T. L., Weisgraber K. H. and Oh S. Y. (1979) Altered metabolism (in vivo and in vitro) of plasma lipoproteins after selective chemical modification of lysine residues of the apoproteins. J. Clin. Invest. 64: 743-750
    • (1979) J. Clin. Invest. , vol.64 , pp. 743-750
    • Mahley, R.W.1    Innerarity, T.L.2    Weisgraber, K.H.3    Oh, S.Y.4
  • 20
    • 0025878638 scopus 로고
    • Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation
    • Linton M. F., Gish R., Hul S. T., Butler E., Esquivel C., Bry W. I. et al. (1991) Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation. J. Clin. Invest. 88: 270-281
    • (1991) J. Clin. Invest. , vol.88 , pp. 270-281
    • Linton, M.F.1    Gish, R.2    Hul, S.T.3    Butler, E.4    Esquivel, C.5    Bry, W.I.6
  • 21
    • 0022350033 scopus 로고
    • Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system
    • Boyles J. K., Pitas R. E., Wilson E., Mahley R. W. and Taylor J. M. (1985) Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J. Clin. Invest. 76: 1501-1513
    • (1985) J. Clin. Invest. , vol.76 , pp. 1501-1513
    • Boyles, J.K.1    Pitas, R.E.2    Wilson, E.3    Mahley, R.W.4    Taylor, J.M.5
  • 22
    • 0023080585 scopus 로고
    • Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins
    • Pitas R. E., Boyles J. K., Lee S. H., Foss D. and Mahley R. W. (1987) Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins. Biochim. Biophys. Acta 917: 148-161
    • (1987) Biochim. Biophys. Acta , vol.917 , pp. 148-161
    • Pitas, R.E.1    Boyles, J.K.2    Lee, S.H.3    Foss, D.4    Mahley, R.W.5
  • 23
    • 0037230328 scopus 로고    scopus 로고
    • Outsourcing in the brain: Do neurons depend on cholesterol delivery by astrocytes?
    • Pfrieger F. W. (2003) Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes? Bioessays 25: 72-78
    • (2003) Bioessays , vol.25 , pp. 72-78
    • Pfrieger, F.W.1
  • 24
    • 0028303072 scopus 로고
    • Apolipoprotein E: Structure-function relationships
    • Weisgraber K. H. (1994) Apolipoprotein E: Structure-function relationships. Adv. Protein Chem. 45: 249-302
    • (1994) Adv. Protein Chem. , vol.45 , pp. 249-302
    • Weisgraber, K.H.1
  • 25
    • 0001575895 scopus 로고
    • Type III hyperlipoproteinemia: The role of apolipoprotein E in normal and abnormal lipoprotein metabolism
    • Scriver C. R., Beaudet A. L., Sly W. S. and Valle D. (eds), McGraw-Hill, New York
    • Mahley R. W. and Rall S. C. Jr (1995) Type III hyperlipoproteinemia: the role of apolipoprotein E in normal and abnormal lipoprotein metabolism. In: The Metabolic and Molecular Bases of Inherited Disease, 7th edn, pp. 1953-1980, Scriver C. R., Beaudet A. L., Sly W. S. and Valle D. (eds), McGraw-Hill, New York
    • (1995) The Metabolic and Molecular Bases of Inherited Disease, 7th Edn , pp. 1953-1980
    • Mahley, R.W.1    Rall Jr., S.C.2
  • 26
    • 0032743737 scopus 로고    scopus 로고
    • Pathogenesis of type III hyperlipoproteinemia (dysbetalipoproteinemia): Questions, quandaries and paradoxes
    • Mahley R. W., Huang Y. and Rall S. C. Jr (1999) Pathogenesis of type III hyperlipoproteinemia (dysbetalipoproteinemia): questions, quandaries and paradoxes. J. Lipid Res. 40: 1933-1949
    • (1999) J. Lipid Res. , vol.40 , pp. 1933-1949
    • Mahley, R.W.1    Huang, Y.2    Rall Jr., S.C.3
  • 27
    • 0031000116 scopus 로고    scopus 로고
    • Cerebrospinal fluid apolipoprotein E level is increased in late-onset Alzheimer's disease
    • Merched A., Blain H., Visvikis S., Herbeth B., Jeandel C. and Siest G. (1997) Cerebrospinal fluid apolipoprotein E level is increased in late-onset Alzheimer's disease. J. Neurol. Sci. 145: 33-39
    • (1997) J. Neurol. Sci. , vol.145 , pp. 33-39
    • Merched, A.1    Blain, H.2    Visvikis, S.3    Herbeth, B.4    Jeandel, C.5    Siest, G.6
  • 28
    • 0034802522 scopus 로고    scopus 로고
    • Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice
    • DeMattos R. B., Brendza R. P., Heuser J. E, Kierson M., Cirrito J. R., Fryer J. et al. (2001) Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice. Neurochem. Int. 39: 415-425
    • (2001) Neurochem. Int. , vol.39 , pp. 415-425
    • DeMattos, R.B.1    Brendza, R.P.2    Heuser, J.E.3    Kierson, M.4    Cirrito, J.R.5    Fryer, J.6
  • 29
    • 0023280054 scopus 로고
    • Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B, E (LDL) receptors in the brain
    • Pitas R. E., Boyles J. K., Lee S. H., Hui D. and Weisgraber K. H. (1987) Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B, E (LDL) receptors in the brain. J. Biol. Chem. 262: 14352-14360
    • (1987) J. Biol. Chem. , vol.262 , pp. 14352-14360
    • Pitas, R.E.1    Boyles, J.K.2    Lee, S.H.3    Hui, D.4    Weisgraber, K.H.5
  • 30
    • 0033571640 scopus 로고    scopus 로고
    • Distinct alterations in phospholipid metabolism in brains of apolipoprotein E-deficient mice
    • Lomnistski L., Oron L., Sklan D. and Michaelson D. M. (1999) Distinct alterations in phospholipid metabolism in brains of apolipoprotein E-deficient mice. J. Neurosci. Res. 58: 586-592
    • (1999) J. Neurosci. Res. , vol.58 , pp. 586-592
    • Lomnistski, L.1    Oron, L.2    Sklan, D.3    Michaelson, D.M.4
  • 31
    • 0037424260 scopus 로고    scopus 로고
    • Novel role for apolipoprotein E in the central nervous system: Modulation of sulfatide content
    • Han X., Cheng H., Fryer D. J., Fagan A. M. and Holtzman D. M. (2003) Novel role for apolipoprotein E in the central nervous system: modulation of sulfatide content. J. Biol. Chem. 278: 8043-8051
    • (2003) J. Biol. Chem. , vol.278 , pp. 8043-8051
    • Han, X.1    Cheng, H.2    Fryer, D.J.3    Fagan, A.M.4    Holtzman, D.M.5
  • 32
    • 0034603415 scopus 로고    scopus 로고
    • The role of apolipoprotein E in Alzheimer's disease, acute brain injury and cerebrovascular disease: Evidence of common mechanisms and utility of animal models
    • Horsburgh K., McCarron M. O., White F. and Nicoll J. A. R. (2000) The role of apolipoprotein E in Alzheimer's disease, acute brain injury and cerebrovascular disease: evidence of common mechanisms and utility of animal models. Neurobiol. Aging 21: 245-255
    • (2000) Neurobiol. Aging , vol.21 , pp. 245-255
    • Horsburgh, K.1    McCarron, M.O.2    White, F.3    Nicoll, J.A.R.4
  • 33
    • 0034575124 scopus 로고    scopus 로고
    • Apolipoprotein E: Far more than a lipid transport protein
    • Mahley R. W. and Rall S. C. Jr (2000) Apolipoprotein E: far more than a lipid transport protein. Annu. Rev. Genom. Hum. Genet. 1: 507-537
    • (2000) Annu. Rev. Genom. Hum. Genet. , vol.1 , pp. 507-537
    • Mahley, R.W.1    Rall Jr., S.C.2
  • 34
    • 0023662285 scopus 로고
    • Lipoprotein uptake by neuronal growth cones in vitro
    • Ignatius M. J., Shooter E. M., Pitas R. E. and Mahley R. W. (1987) Lipoprotein uptake by neuronal growth cones in vitro. Science 236: 959-962
    • (1987) Science , vol.236 , pp. 959-962
    • Ignatius, M.J.1    Shooter, E.M.2    Pitas, R.E.3    Mahley, R.W.4
  • 36
    • 0028822219 scopus 로고
    • Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line
    • Holtzman D. M., Pitas R. E., Kilbridge J., Nathan B., Mahley R. W., Bu G. et al. (1995) Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line. Proc. Natl. Acad. Sci. USA 92: 9480-9484
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9480-9484
    • Holtzman, D.M.1    Pitas, R.E.2    Kilbridge, J.3    Nathan, B.4    Mahley, R.W.5    Bu, G.6
  • 37
    • 0033564771 scopus 로고    scopus 로고
    • Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- Mice: Isoform-specific effects on neurodegeneration
    • Buttini M., Orth M., Bellosta S., Akeefe H., Pitas R. E., Wyss-Coray T. et al. (1999) Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration. J. Neurosci. 19: 4867-4880
    • (1999) J. Neurosci. , vol.19 , pp. 4867-4880
    • Buttini, M.1    Orth, M.2    Bellosta, S.3    Akeefe, H.4    Pitas, R.E.5    Wyss-Coray, T.6
  • 38
    • 0025149375 scopus 로고
    • Accumulation of apolipoproteins in the regenerating and remyelinating mammalian peripheral nerve. Identification of apolipoprotein D, apolipoprotein A-IV, apolipoprotein E and apolipoprotein A-I
    • Boyles J. K., Notterpek L. M. and Anderson L. J. (1990) Accumulation of apolipoproteins in the regenerating and remyelinating mammalian peripheral nerve. Identification of apolipoprotein D, apolipoprotein A-IV, apolipoprotein E and apolipoprotein A-I. J. Biol. Chem. 265: 17805-17815
    • (1990) J. Biol. Chem. , vol.265 , pp. 17805-17815
    • Boyles, J.K.1    Notterpek, L.M.2    Anderson, L.J.3
  • 39
  • 40
    • 0027298061 scopus 로고
    • Cholesterol synthesis and lipoprotein reuptake during synaptic remodeling in hippocampus in adult rats
    • Poirier J., Baccichet A., Dea D. and Gauthier S. (1993) Cholesterol synthesis and lipoprotein reuptake during synaptic remodeling in hippocampus in adult rats. Neuroscience 55: 81-90
    • (1993) Neuroscience , vol.55 , pp. 81-90
    • Poirier, J.1    Baccichet, A.2    Dea, D.3    Gauthier, S.4
  • 42
    • 0027411295 scopus 로고
    • Nerve regeneration occurs in the absence of apolipoprotein E in mice
    • Popko B., Goodrum J. F., Bouldin T. W., Zhang S. H. and Maeda N. (1993) Nerve regeneration occurs in the absence of apolipoprotein E in mice. J. Neurochem. 60: 1155-1158
    • (1993) J. Neurochem. , vol.60 , pp. 1155-1158
    • Popko, B.1    Goodrum, J.F.2    Bouldin, T.W.3    Zhang, S.H.4    Maeda, N.5
  • 44
    • 0029844205 scopus 로고    scopus 로고
    • Human apolipoprotein E: The Alzheimer's disease connection
    • Weisgraber K. H. and Mahley R. W. (1996) Human apolipoprotein E: the Alzheimer's disease connection. FASEB J. 10: 1485-1494
    • (1996) FASEB J. , vol.10 , pp. 1485-1494
    • Weisgraber, K.H.1    Mahley, R.W.2
  • 45
    • 0026542786 scopus 로고
    • Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid
    • Wisniewski T. and Frangione B. (1992) Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid. Neurosci. Lett. 135: 235-238
    • (1992) Neurosci. Lett. , vol.135 , pp. 235-238
    • Wisniewski, T.1    Frangione, B.2
  • 46
    • 12044254746 scopus 로고
    • Binding of human apolipoprotein E to synthetic amyloid β peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
    • Strittmatter W. J., Weisgraber K. H., Huang D. Y., Dong L., Salvesen G. S., Pericak-Vance M. et al. (1993) Binding of human apolipoprotein E to synthetic amyloid β peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 90: 8098-8102
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8098-8102
    • Strittmatter, W.J.1    Weisgraber, K.H.2    Huang, D.Y.3    Dong, L.4    Salvesen, G.S.5    Pericak-Vance, M.6
  • 47
    • 0031278270 scopus 로고    scopus 로고
    • Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition
    • Bales K. R., Verina T., Dodel R. C., Du Y., Altstiel L., Bender M. et al. (1997) Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition. Nat. Genet. 17: 263-264
    • (1997) Nat. Genet. , vol.17 , pp. 263-264
    • Bales, K.R.1    Verina, T.2    Dodel, R.C.3    Du, Y.4    Altstiel, L.5    Bender, M.6
  • 48
    • 4243215848 scopus 로고    scopus 로고
    • Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
    • Holtzman D. M., Bales K. R., Tenkova T., Fagan A. M., Parsadanian M., Sartorius L. J. et al. (2000) Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 97: 2892-2897
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 2892-2897
    • Holtzman, D.M.1    Bales, K.R.2    Tenkova, T.3    Fagan, A.M.4    Parsadanian, M.5    Sartorius, L.J.6
  • 49
    • 9144224765 scopus 로고    scopus 로고
    • ApoE and clusterin cooperatively suppress Aβ levels and deposition: Evidence that ApoE regulates extracellular Aβ metabolism in vivo
    • DeMattos R. B., Cirrito J. R., Parsadanian M., May P. C., O'Dell M. A., Taylor J. W. et al. (2004) ApoE and clusterin cooperatively suppress Aβ levels and deposition: evidence that ApoE regulates extracellular Aβ metabolism in vivo. Neuron 41: 193-202
    • (2004) Neuron , vol.41 , pp. 193-202
    • DeMattos, R.B.1    Cirrito, J.R.2    Parsadanian, M.3    May, P.C.4    O'Dell, M.A.5    Taylor, J.W.6
  • 50
    • 0028986690 scopus 로고
    • Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury
    • Nicoll J. A., Roberts G. W. and Graham D. I. (1995) Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury. Nat. Med. 1: 135-137
    • (1995) Nat. Med. , vol.1 , pp. 135-137
    • Nicoll, J.A.1    Roberts, G.W.2    Graham, D.I.3
  • 51
    • 0030770308 scopus 로고    scopus 로고
    • Association of apolipoprotein E polymorphism with outcome after head injury
    • Teasdale G. M., Nicoll J. A., Murray G. and Fiddes M. (1997) Association of apolipoprotein E polymorphism with outcome after head injury. Lancet 350: 1069-1071
    • (1997) Lancet , vol.350 , pp. 1069-1071
    • Teasdale, G.M.1    Nicoll, J.A.2    Murray, G.3    Fiddes, M.4
  • 52
    • 0033554880 scopus 로고    scopus 로고
    • Apolipoprotein E-epsilon4 genotype predicts a poor outcome in survivors of traumatic brain injury
    • Friedman G., Froom P., Sazbon L., Grinblatt I., Shochina M., Tsenter J. et al. (1999) Apolipoprotein E-epsilon4 genotype predicts a poor outcome in survivors of traumatic brain injury. Neurology 52: 244-248
    • (1999) Neurology , vol.52 , pp. 244-248
    • Friedman, G.1    Froom, P.2    Sazbon, L.3    Grinblatt, I.4    Shochina, M.5    Tsenter, J.6
  • 53
    • 0037972285 scopus 로고    scopus 로고
    • Genetic vulnerability following traumatic brain injury: The role of apolipoprotein E
    • Nathoo N., Chetty R., van Dellen J. R. and Barnett G. H. (2003) Genetic vulnerability following traumatic brain injury: the role of apolipoprotein E. Mol. Pathol. 56: 132-136
    • (2003) Mol. Pathol. , vol.56 , pp. 132-136
    • Nathoo, N.1    Chetty, R.2    Van Dellen, J.R.3    Barnett, G.H.4
  • 55
    • 0032778592 scopus 로고    scopus 로고
    • Intracerebral hemorrhage outcome: Apolipoprotein E genotype, hematoma and edema volumes
    • McCarron M. O., Hoffmann K. L., DeLong D. M., Gray L., Saunders A. M. et al. (1999) Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma and edema volumes. Neurology 53: 2176-2179
    • (1999) Neurology , vol.53 , pp. 2176-2179
    • McCarron, M.O.1    Hoffmann, K.L.2    DeLong, D.M.3    Gray, L.4    Saunders, A.M.5
  • 56
    • 0030614814 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation
    • Slooter A. J., Tang M. X., van Duijn C. M., Stern Y., Ott A., Bell K. et al. (1997) Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation. J. Am. Med. Assoc. 277: 818-821
    • (1997) J. Am. Med. Assoc. , vol.277 , pp. 818-821
    • Slooter, A.J.1    Tang, M.X.2    Van Duijn, C.M.3    Stern, Y.4    Ott, A.5    Bell, K.6
  • 57
    • 0030881644 scopus 로고    scopus 로고
    • Modulation of the age at onset of Parkinson's disease by apolipoprotein E genotype
    • Zarepesi S., Kaye J., Camicioli R., Grimslid H., Oken B., Litt M. et al. (1997) Modulation of the age at onset of Parkinson's disease by apolipoprotein E genotype. Ann. Neurol. 42: 655-658
    • (1997) Ann. Neurol. , vol.42 , pp. 655-658
    • Zarepesi, S.1    Kaye, J.2    Camicioli, R.3    Grimslid, H.4    Oken, B.5    Litt, M.6
  • 58
    • 0024574009 scopus 로고
    • A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve
    • Boyles J. K., Zoellner C. D., Anderson L. J., Kosik L. M., Pitas R. E., Weisgraber K. H. et al. (1989) A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve. J. Clin. Invest. 83: 1015-1031
    • (1989) J. Clin. Invest. , vol.83 , pp. 1015-1031
    • Boyles, J.K.1    Zoellner, C.D.2    Anderson, L.J.3    Kosik, L.M.4    Pitas, R.E.5    Weisgraber, K.H.6
  • 59
    • 0025946238 scopus 로고
    • Cholesterol from degenerating nerve myelin becomes associated with lipoproteins containing apolipoprotein E
    • Goodrum J. F. (1991) Cholesterol from degenerating nerve myelin becomes associated with lipoproteins containing apolipoprotein E. J. Neurochem. 56: 2082-2086
    • (1991) J. Neurochem. , vol.56 , pp. 2082-2086
    • Goodrum, J.F.1
  • 60
    • 0026443801 scopus 로고
    • Effects of apolipoprotein E, beta-very low density lipoproteins and cholesterol on the extension of neurites by rabbit dorsal root ganglion neurons in vitro
    • Handelmann G. E., Boyles J. K., Weisgraber K. H., Mahley R. W. and Pitas R. E. (1992) Effects of apolipoprotein E, beta-very low density lipoproteins and cholesterol on the extension of neurites by rabbit dorsal root ganglion neurons in vitro. J. Lipid Res. 33: 1677-1688
    • (1992) J. Lipid Res. , vol.33 , pp. 1677-1688
    • Handelmann, G.E.1    Boyles, J.K.2    Weisgraber, K.H.3    Mahley, R.W.4    Pitas, R.E.5
  • 61
    • 0040177065 scopus 로고
    • Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins
    • Kowal R. C., Herz J., Goldstein J. L., Esser V. and Blown M. S. (1989) Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins. Proc. Natl. Acad. Sci. USA 86: 5810-5814
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 5810-5814
    • Kowal, R.C.1    Herz, J.2    Goldstein, J.L.3    Esser, V.4    Blown, M.S.5
  • 62
    • 0141653274 scopus 로고    scopus 로고
    • Global analysis of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: A bridge to lipidomics
    • Han X. and Gross R. W. (2003) Global analysis of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics. J. Lipid Res. 44: 1071-1079
    • (2003) J. Lipid Res. , vol.44 , pp. 1071-1079
    • Han, X.1    Gross, R.W.2
  • 63
    • 18344393519 scopus 로고    scopus 로고
    • Shotgun lipidomics: Electrospray ionization mass spectrometric analysis and quantitation of the cellular lipidomes directly from crude extracts of biological samples
    • in press
    • Han X. and Gross R. W. (2004) Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of the cellular lipidomes directly from crude extracts of biological samples. Mass Spec. Rev., in press
    • (2004) Mass Spec. Rev.
    • Han, X.1    Gross, R.W.2
  • 65
  • 66
    • 0028173897 scopus 로고
    • Structures and functions of multiligand lipoprotein receptors: Macrophage scavenger receptors and LDL receptor-related protein (LRP)
    • Krieger M. and Herz J. (1994) Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP). Ann. Rev. Biochem. 63: 601-637
    • (1994) Ann. Rev. Biochem. , vol.63 , pp. 601-637
    • Krieger, M.1    Herz, J.2
  • 68
    • 0031407609 scopus 로고    scopus 로고
    • Chemistry and functional distribution of sulfoglycolipids
    • Ishizuka I. (1997) Chemistry and functional distribution of sulfoglycolipids. Prog. Lipid Res. 36: 245-319
    • (1997) Prog. Lipid Res. , vol.36 , pp. 245-319
    • Ishizuka, I.1
  • 69
    • 0000497407 scopus 로고    scopus 로고
    • Metachromatic leukodystrophy: Lysosomal disorders
    • Scriver C. R., Beaudet A. L., Sly W. S. and Valle D. (eds), 8th edn, McGraw-Hill, New York
    • von Figura K., Gieselmann V. and Jaeken J. (2001) Metachromatic leukodystrophy: Lysosomal disorders. In: The Metabolic and Molecular Bases of Inherited Diseases, Scriver C. R., Beaudet A. L., Sly W. S. and Valle D. (eds), 8th edn, pp. 3695-3724, McGraw-Hill, New York
    • (2001) The Metabolic and Molecular Bases of Inherited Diseases , pp. 3695-3724
    • Von Figura, K.1    Gieselmann, V.2    Jaeken, J.3
  • 70
    • 0029851157 scopus 로고    scopus 로고
    • Functional breakdown of the lipid bilayer of the myelin membrane in central and peripheral nervous system by disrupted galactocerebroside synthesis
    • Bosio A., Binczek E. and Stoffel W. (1996) Functional breakdown of the lipid bilayer of the myelin membrane in central and peripheral nervous system by disrupted galactocerebroside synthesis. Proc. Natl. Acad. Sci. USA 93: 13280-13285
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13280-13285
    • Bosio, A.1    Binczek, E.2    Stoffel, W.3
  • 71
    • 0030602822 scopus 로고    scopus 로고
    • Myelination in the absence of galactocerebroside and sulfatide: Normal structure with abnormal function and regional instability
    • Coetzee T., Fujita N., Dupree J., Shi R., Blight A., Suzuki K. et al. (1996) Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability. Cell 86: 209-219
    • (1996) Cell , vol.86 , pp. 209-219
    • Coetzee, T.1    Fujita, N.2    Dupree, J.3    Shi, R.4    Blight, A.5    Suzuki, K.6
  • 72
    • 0031982356 scopus 로고    scopus 로고
    • Galactosphingolipids and axono-glial interaction in myelin of the central nervous system
    • Bosio A., Büssow H., Adam J. and Stoffel W. (1998) Galactosphingolipids and axono-glial interaction in myelin of the central nervous system. Cell Tissue Res. 292: 199-210
    • (1998) Cell Tissue Res. , vol.292 , pp. 199-210
    • Bosio, A.1    Büssow, H.2    Adam, J.3    Stoffel, W.4
  • 73
    • 0032032415 scopus 로고    scopus 로고
    • New perspectives on the function of myelin galactolipids
    • Coetzee T., Suzuki K. and Popko B. (1998) New perspectives on the function of myelin galactolipids. Trends Neurosci. 21: 126-130
    • (1998) Trends Neurosci. , vol.21 , pp. 126-130
    • Coetzee, T.1    Suzuki, K.2    Popko, B.3
  • 76
    • 0036677303 scopus 로고    scopus 로고
    • Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: Potential role in disease pathogenesis
    • Han X., Holtzman D. M., McKeel D. W. Jr, Kelley J. and Morris J. C. (2002) Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis. J. Neurochem. 82: 809-818
    • (2002) J. Neurochem. , vol.82 , pp. 809-818
    • Han, X.1    Holtzman, D.M.2    McKeel Jr., D.W.3    Kelley, J.4    Morris, J.C.5
  • 77
    • 0038479920 scopus 로고    scopus 로고
    • Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia
    • Han X., Fagan A. M., Cheng H., Morris J. C., Xiong C. and Holtzman D. M. (2003) Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia. Ann. Neurol. 54: 115-119
    • (2003) Ann. Neurol. , vol.54 , pp. 115-119
    • Han, X.1    Fagan, A.M.2    Cheng, H.3    Morris, J.C.4    Xiong, C.5    Holtzman, D.M.6
  • 78
    • 2542579484 scopus 로고    scopus 로고
    • Specificity and potential mechanism of sulfatide deficiency in Alzheimer's disease: An electrospray ionization mass spectrometric study
    • Cheng H., Xu J., McKeel D. W. Jr and Han X. (2003) Specificity and potential mechanism of sulfatide deficiency in Alzheimer's disease: an electrospray ionization mass spectrometric study. Cell. Mol. Biol. 49: 809-818
    • (2003) Cell. Mol. Biol. , vol.49 , pp. 809-818
    • Cheng, H.1    Xu, J.2    McKeel Jr., D.W.3    Han, X.4
  • 79
    • 0037217410 scopus 로고    scopus 로고
    • Correlation between intrathecal sulfatide and TNF-a levels in patients with vascular dementia
    • Tarkowski E., Tullberg M., Fredman P. and Wikkelsoe C. (2003) Correlation between intrathecal sulfatide and TNF-a levels in patients with vascular dementia. Dement. Geriat. Cogn. Disord. 15: 207-211
    • (2003) Dement. Geriat. Cogn. Disord. , vol.15 , pp. 207-211
    • Tarkowski, E.1    Tullberg, M.2    Fredman, P.3    Wikkelsoe, C.4
  • 80
    • 0019464628 scopus 로고
    • Immunohistochemical localization of galactosyl and sulfogalactosyl ceramide in the brain of the 30-day-old mouse
    • Zalc B., Monge M., Dupouey P., Hauw J. J. and Baumann N. A. (1981) Immunohistochemical localization of galactosyl and sulfogalactosyl ceramide in the brain of the 30-day-old mouse. Brain Res. 211: 341-354
    • (1981) Brain Res. , vol.211 , pp. 341-354
    • Zalc, B.1    Monge, M.2    Dupouey, P.3    Hauw, J.J.4    Baumann, N.A.5
  • 81
    • 0032101216 scopus 로고    scopus 로고
    • Intracellular sulfatide expression in a subpopulation of astrocytes in primary cultures
    • Berntson Z., Hansson E., Ronnback L. and Fredman P. (1998) Intracellular sulfatide expression in a subpopulation of astrocytes in primary cultures. J. Neurosci. Res. 52: 559-568
    • (1998) J. Neurosci. Res. , vol.52 , pp. 559-568
    • Berntson, Z.1    Hansson, E.2    Ronnback, L.3    Fredman, P.4
  • 83
    • 0027183774 scopus 로고
    • Sulfated glycolipids are ligands for a lymphocyte homing receptor, L-selectin (LECAM-1), binding epitope in sulfated sugar chain
    • Suzuki Y., Toda Y., Tamatani T., Watanabe T., Suzuki T., Nakao T. et al. (1993) Sulfated glycolipids are ligands for a lymphocyte homing receptor, L-selectin (LECAM-1), binding epitope in sulfated sugar chain. Biochem. Biophys. Res. Commun. 190: 426-434
    • (1993) Biochem. Biophys. Res. Commun. , vol.190 , pp. 426-434
    • Suzuki, Y.1    Toda, Y.2    Tamatani, T.3    Watanabe, T.4    Suzuki, T.5    Nakao, T.6
  • 85
    • 0029183930 scopus 로고
    • Sulfatide, a specific sugar ligand for L-selectin, blocks CC14-induced liver inflammation in rats
    • Kajihara J., Ye G., Kato K. and Suzuki Y. (1995) Sulfatide, a specific sugar ligand for L-selectin, blocks CC14-induced liver inflammation in rats. Biosci. Biotechnol. Biochem. 59: 155-157
    • (1995) Biosci. Biotechnol. Biochem. , vol.59 , pp. 155-157
    • Kajihara, J.1    Ye, G.2    Kato, K.3    Suzuki, Y.4
  • 87
    • 0035826682 scopus 로고    scopus 로고
    • Biosynthesis of L-selectin ligands: Sulfation of sialyl Lewis x-related oligosaccharides by a family of Glc-NAc-6-sulfotransferases
    • Bowman K. G., Cook B. N., de Graffenried C. L. and Bertozzi C. R. (2001) Biosynthesis of L-selectin ligands: sulfation of sialyl Lewis x-related oligosaccharides by a family of Glc-NAc-6-sulfotransferases. Biochemistry 40: 5382-5391
    • (2001) Biochemistry , vol.40 , pp. 5382-5391
    • Bowman, K.G.1    Cook, B.N.2    De Graffenried, C.L.3    Bertozzi, C.R.4
  • 88
    • 0035846556 scopus 로고    scopus 로고
    • Role for sulfatides in platelet aggregation
    • Merten M. and Thiagarajan P. (2001) Role for sulfatides in platelet aggregation. Circulation 104: 2955-2960
    • (2001) Circulation , vol.104 , pp. 2955-2960
    • Merten, M.1    Thiagarajan, P.2
  • 91
    • 0032785877 scopus 로고    scopus 로고
    • The evolution of Alzheimer's disease, the reproductive schedule and apoE isoforms
    • Finch C. E. and Sapolsky R. M. (1999) The evolution of Alzheimer's disease, the reproductive schedule and apoE isoforms. Neurobiol. Aging 20: 407-428
    • (1999) Neurobiol. Aging , vol.20 , pp. 407-428
    • Finch, C.E.1    Sapolsky, R.M.2
  • 92
    • 0026514988 scopus 로고
    • Modulation of plasma triglyceride levels by apoE phenotype: A meta-analysis
    • Dallongeville J., Lussier-Cacan S. and Davignon J. (1992) Modulation of plasma triglyceride levels by apoE phenotype: a meta-analysis. J. Lipid Res. 33: 447-454
    • (1992) J. Lipid Res. , vol.33 , pp. 447-454
    • Dallongeville, J.1    Lussier-Cacan, S.2    Davignon, J.3
  • 93
    • 0023117993 scopus 로고
    • Apolipoprotein E polymorphism in health and disease
    • Utermann G. (1987) Apolipoprotein E polymorphism in health and disease. Am. Heart J. 113: 433-440
    • (1987) Am. Heart J. , vol.113 , pp. 433-440
    • Utermann, G.1
  • 94
    • 0026349433 scopus 로고
    • The apolipoprotein E polymorphism: A comparison of allele frequencies and effects in nine populations
    • Hallman D. M., Boerwinkle E., Saha N., Sandholzer C., Menzel H. J., Csazar A. et al. (1991) The apolipoprotein E polymorphism: a comparison of allele frequencies and effects in nine populations. Am. J. Hum. Genet. 49: 338-349
    • (1991) Am. J. Hum. Genet. , vol.49 , pp. 338-349
    • Hallman, D.M.1    Boerwinkle, E.2    Saha, N.3    Sandholzer, C.4    Menzel, H.J.5    Csazar, A.6
  • 96
    • 0030723754 scopus 로고    scopus 로고
    • Central nervous system lipoproteins in Alzheimer's disease
    • Montine T. J., Montine K. S. and Swift L. L. (1997) Central nervous system lipoproteins in Alzheimer's disease. Am. J. Pathol. 151: 1571-1575
    • (1997) Am. J. Pathol. , vol.151 , pp. 1571-1575
    • Montine, T.J.1    Montine, K.S.2    Swift, L.L.3
  • 98
    • 0031914130 scopus 로고    scopus 로고
    • Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes
    • Rebeck G. W., Alonzo N. C., Berezovska O., Harr S. D., Knowles R. B., Growdon J. H. et al. (1998) Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes. Exp. Neurol. 149: 175-182
    • (1998) Exp. Neurol. , vol.149 , pp. 175-182
    • Rebeck, G.W.1    Alonzo, N.C.2    Berezovska, O.3    Harr, S.D.4    Knowles, R.B.5    Growdon, J.H.6
  • 99
    • 0031936181 scopus 로고    scopus 로고
    • Novel large apolipoprotein E-containing lipoproteins of density 1.006-1.060 g/ml in human cerebrospinal fluid
    • Guyton J. R., Miller S. E., Martin M. E., Khan W. A., Roses A. D. and Strittmatter W. J. (1998) Novel large apolipoprotein E-containing lipoproteins of density 1.006-1.060 g/ml in human cerebrospinal fluid. J. Neurochem. 70: 1235-1240
    • (1998) J. Neurochem. , vol.70 , pp. 1235-1240
    • Guyton, J.R.1    Miller, S.E.2    Martin, M.E.3    Khan, W.A.4    Roses, A.D.5    Strittmatter, W.J.6
  • 100
    • 0032405857 scopus 로고    scopus 로고
    • Reduced levels of cholesterol, phospholipids and fatty acids in cerebrospinal fluid of Alzheimer disease patients are not related to apolipoprotein E4
    • Mulder M., Ravid R., Swaab D. F., de Kloet E. R., Haasdijk E. D., Julk J. et al. (1998) Reduced levels of cholesterol, phospholipids and fatty acids in cerebrospinal fluid of Alzheimer disease patients are not related to apolipoprotein E4. Alz. Dis. Assoc. Disord. 12: 198-203
    • (1998) Alz. Dis. Assoc. Disord. , vol.12 , pp. 198-203
    • Mulder, M.1    Ravid, R.2    Swaab, D.F.3    De Kloet, E.R.4    Haasdijk, E.D.5    Julk, J.6
  • 101
    • 0032824010 scopus 로고    scopus 로고
    • Characterization of apolipoprotein E-containing lipoproteins in cerebrospinal fluid: Effect of phenotype on the distribution of apolipoprotein E
    • Yamauchi K., Tozuka M., Hidaka H., Hidaka E., Kondo Y. and Katsuyama T. (1999) Characterization of apolipoprotein E-containing lipoproteins in cerebrospinal fluid: effect of phenotype on the distribution of apolipoprotein E. Clin. Chem. 45: 1431-1438
    • (1999) Clin. Chem. , vol.45 , pp. 1431-1438
    • Yamauchi, K.1    Tozuka, M.2    Hidaka, H.3    Hidaka, E.4    Kondo, Y.5    Katsuyama, T.6
  • 102
    • 0032917743 scopus 로고    scopus 로고
    • Apolipoprotein E in cerebrospinal fluid: Relation to phenotype and plasma apolipoprotein E concentrations
    • Yamauchi K., Tozuka M., Nakabayashi T., Sugano M., Hidaka H., Kondo Y. et al. (1999) Apolipoprotein E in cerebrospinal fluid: relation to phenotype and plasma apolipoprotein E concentrations. Clin. Chem. 45: 497-504
    • (1999) Clin. Chem. , vol.45 , pp. 497-504
    • Yamauchi, K.1    Tozuka, M.2    Nakabayashi, T.3    Sugano, M.4    Hidaka, H.5    Kondo, Y.6
  • 103
    • 0033624283 scopus 로고    scopus 로고
    • Differences in the Abeta40/Abeta42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype
    • Fagan A. M., Younkin L. H., Morris J. C., Fryer J. D., Cole T. G., Younkin S. G. et al. (2000) Differences in the Abeta40/Abeta42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype. Ann. Neurol. 48: 201-210
    • (2000) Ann. Neurol. , vol.48 , pp. 201-210
    • Fagan, A.M.1    Younkin, L.H.2    Morris, J.C.3    Fryer, J.D.4    Cole, T.G.5    Younkin, S.G.6
  • 104
    • 0035901715 scopus 로고    scopus 로고
    • Differential effects of lovastatin treatment on brain cholesterol levels in normal and ApoE-deficient mice
    • Eckert G. P., Kirsch C. and Mueller W. E. (2001) Differential effects of lovastatin treatment on brain cholesterol levels in normal and ApoE-deficient mice. Neuroreport 12: 883-887
    • (2001) Neuroreport , vol.12 , pp. 883-887
    • Eckert, G.P.1    Kirsch, C.2    Mueller, W.E.3
  • 105
    • 0037171006 scopus 로고    scopus 로고
    • Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice
    • Hayashi H., Igbavboa U., Hamanaka H., Kobayashi M., Fujita S. C., Wood W. G. et al. (2002) Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice. Neuroreport 13: 383-386
    • (2002) Neuroreport , vol.13 , pp. 383-386
    • Hayashi, H.1    Igbavboa, U.2    Hamanaka, H.3    Kobayashi, M.4    Fujita, S.C.5    Wood, W.G.6
  • 107
    • 0032568843 scopus 로고    scopus 로고
    • Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol
    • Rowland D. S., Trusko S. P., Savage M. J., Reaume A. G., Lang D. M., Hirsch J. D. et al. (1998) Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol. J. Biol. Chem. 273: 16576-16582
    • (1998) J. Biol. Chem. , vol.273 , pp. 16576-16582
    • Rowland, D.S.1    Trusko, S.P.2    Savage, M.J.3    Reaume, A.G.4    Lang, D.M.5    Hirsch, J.D.6
  • 109
    • 0036963532 scopus 로고    scopus 로고
    • Increased amyloid-levels in APPSWE transgenic mice treated chronically with a physiological high-fat high-cholesterol diet
    • Levin-Allerhand J. A., Lominska C. E. and Smith J. D. (2002) Increased amyloid-levels in APPSWE transgenic mice treated chronically with a physiological high-fat high-cholesterol diet. J. Nutr. Health Aging 6: 315-319
    • (2002) J. Nutr. Health Aging , vol.6 , pp. 315-319
    • Levin-Allerhand, J.A.1    Lominska, C.E.2    Smith, J.D.3
  • 110
    • 4143080956 scopus 로고    scopus 로고
    • The effects of apolipoprotein E genotype on brain lipid metabolism
    • Tietz A., Oron L., Mazliah E. and Michaelson D. M. (2002) The effects of apolipoprotein E genotype on brain lipid metabolism. Adv. Behav. Biol. 51: 33-38
    • (2002) Adv. Behav. Biol. , vol.51 , pp. 33-38
    • Tietz, A.1    Oron, L.2    Mazliah, E.3    Michaelson, D.M.4
  • 112
    • 0037710127 scopus 로고    scopus 로고
    • Cholesterol homeostasis and function in neurons of the central nervous system
    • Pfrieger F. W. (2003) Cholesterol homeostasis and function in neurons of the central nervous system. Cell. Mol. Life Sci. 60: 1158-1171
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 1158-1171
    • Pfrieger, F.W.1
  • 113
  • 114
    • 0033968648 scopus 로고    scopus 로고
    • Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture
    • Michikawa M., Fan Q.-W., Isobe I. and Yanagisawa K. (2000) Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture. J. Neurochem. 74: 1008-1016
    • (2000) J. Neurochem. , vol.74 , pp. 1008-1016
    • Michikawa, M.1    Fan, Q.-W.2    Isobe, I.3    Yanagisawa, K.4
  • 115
    • 0037119427 scopus 로고    scopus 로고
    • Apolipoprotein E (apoE) isoform-dependent lipid release from astrocytes prepared from human apoE3 and apoE4 knock-in mice
    • Gong J.-S., Kobayashi M., Hayashi H., Zou K., Sawamura N., Fujita S. C. et al. (2002) Apolipoprotein E (apoE) isoform-dependent lipid release from astrocytes prepared from human apoE3 and apoE4 knock-in mice. J. Biol. Chem. 277: 29919-29926
    • (2002) J. Biol. Chem. , vol.277 , pp. 29919-29926
    • Gong, J.-S.1    Kobayashi, M.2    Hayashi, H.3    Zou, K.4    Sawamura, N.5    Fujita, S.C.6
  • 116
    • 0032839939 scopus 로고    scopus 로고
    • Increased cerebral cortical lipid peroxidation and abnormal phospholipids in aged homozygous apoE-deficient C57BL/6J mice
    • Montine T. J, Montine K. S., Olson S. J., Graham D. G., Roberts L. J. II., Morrow J. D. et al. (1999). Increased cerebral cortical lipid peroxidation and abnormal phospholipids in aged homozygous apoE-deficient C57BL/6J mice. Exp. Neurol. 158: 234-241
    • (1999) Exp. Neurol. , vol.158 , pp. 234-241
    • Montine, T.J.1    Montine, K.S.2    Olson, S.J.3    Graham, D.G.4    Roberts II, L.J.5    Morrow, J.D.6
  • 117
    • 0036317070 scopus 로고    scopus 로고
    • A new role for apolipoprotein E: Modulating transport of polyunsaturated phospholipid molecular species in synaptic plasma membranes
    • Igbavboa U., Hamilton J., Kim H.-Y., Sun G. Y. and Wood W. G. (2002) A new role for apolipoprotein E: modulating transport of polyunsaturated phospholipid molecular species in synaptic plasma membranes. J. Neurochem. 80: 255-261
    • (2002) J. Neurochem. , vol.80 , pp. 255-261
    • Igbavboa, U.1    Hamilton, J.2    Kim, H.-Y.3    Sun, G.Y.4    Wood, W.G.5
  • 118
    • 0035023152 scopus 로고    scopus 로고
    • Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: Molecular characterization using electrospray ionization mass spectrometry
    • Han X., Holtzman D. M. and McKeel D. W. Jr (2001) Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry. J. Neurochem. 77: 1168-1180
    • (2001) J. Neurochem. , vol.77 , pp. 1168-1180
    • Han, X.1    Holtzman, D.M.2    McKeel Jr., D.W.3
  • 119
    • 0025826774 scopus 로고
    • Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning
    • Poirier J., Hess M., May P. C. and Finch C. E. (1991) Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning. Brain Res. Mol. Brain Res. 11: 97-106
    • (1991) Brain Res. Mol. Brain Res. , vol.11 , pp. 97-106
    • Poirier, J.1    Hess, M.2    May, P.C.3    Finch, C.E.4
  • 120
    • 0031079601 scopus 로고    scopus 로고
    • Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro
    • Stone D. J., Rozovsky I., Morgan T. E., Anderson C. P., Hajian H. and Finch C. E. (1997) Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro. Exp. Neurol. 143: 313-318
    • (1997) Exp. Neurol. , vol.143 , pp. 313-318
    • Stone, D.J.1    Rozovsky, I.2    Morgan, T.E.3    Anderson, C.P.4    Hajian, H.5    Finch, C.E.6
  • 121
    • 0024534881 scopus 로고
    • Oligodendrocytes but not astrocytes express apolipoprotein E after injury of rat optic nerve
    • Stoll G., Meuller H. W., Trapp B. D. and Griffin J. W. (1989) Oligodendrocytes but not astrocytes express apolipoprotein E after injury of rat optic nerve. Glia 2: 170-176
    • (1989) Glia , vol.2 , pp. 170-176
    • Stoll, G.1    Meuller, H.W.2    Trapp, B.D.3    Griffin, J.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.