Cerebrospinal fluid apolipoprotein E level is increased in late-onset Alzheimer's disease

Journal of the Neurological Sciences

Volumn 145, Issue 1, 1997, Pages 33-39

  Merched, A ^a   Blain, H ^a,b   Visvikis, S ^a   Herbeth, B ^a   Jeandel, C ^b   Siest, G ^a  

^a Centre du Medicament URA CNRS 597   (France)

^b CHU NANCY BRABOIS   (France)

Author keywords

Alzheimer's disease (AD); apolipoprotein E (apoE); cerebrospinal fluid (CSF); neurological diseases

Indexed keywords

APOLIPOPROTEIN E;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CEREBROSPINAL FLUID; CLINICAL ARTICLE; CONTROLLED STUDY; ENCEPHALITIS; FEMALE; HUMAN; LOW BACK PAIN; MALE; NEUROLOGIC DISEASE; PRIORITY JOURNAL;

AGE OF ONSET; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEINS E; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; LOW BACK PAIN; MALE; MENINGOENCEPHALITIS; MIDDLE AGED; MOTOR NEURON DISEASE; PHENOTYPE; VASCULAR DISEASES;

EID: 0031000116     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(96)00234-1     Document Type: Article

References (36)

1. Blennow, K., Hesse, C. and Freaman, P. (1994) Cerebrospinal fluid apolipoprotein E is reduced in Alzheimer's disease. NeuroReport, 5: 2534-2536.
2. Bohnet, K., Pillot, T., Visvikis, S., Sabolovic, N., and Siest, G. (1996) Apolipoprotein (apo) E genotype and apoE concentration determine binding of normal very low density lipoproteins to HepG2 cell surface receptors. J. Lipid Res., 37: 1316-1324.
3. Cameron, B.M., Vanderputten, D.M, and Merril, C.R. (1995) Preliminary study of an increase of a plasma apolipoprotein E variant associated with peripheral nerve damage. Spine, 20: 581-589.
4. Carlsson, J., Armstrong, V.W., Reiber, H., Felgenhauer, K. and Seidel D. (1991) Clinical relevance of the quantification of apolipoprotein E in cerebrospinal fluid. Clin. Chim. Acta, 196: 167-176.
5. Diedrich, J.F., Minnigan, H., Carp, RI., Whitaker, J.N., Race, R., Frey II, W. and Haase, A.T. (1991) Neuropathlogical changes in scarpie and Alzheimer's disease are associated with inceased expression of apolipoprotein E and cathepsin D in astrocytes. J. Virol., 65: 4759-4768.
6. Folstein, M.R., Folstein, S.C., and McHugh G. (1975) 'Mini-mental state': a pratical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res., 12: 189-198.
7. Gaillard, O., Gervais, A., Meillet, D., Delattre, J., Lyon-Caen, O. and Schuller, E. (1996) The apolipoprotein E intrathecal synthesis is decreased in multiple sclerosis. Ann. Clin. Biochem., in press.
8. Handelman, G.E., Boyles, J.K., Weisgraber, K.H., Mahley, R.Y. and Pitas, R.E. (1992) Effects of apolipoprotein E β-very low density lipoproteins, and cholesterol on the extension of neuntes by rabbit dorsal root ganglion neurons in vitro. J. Lipid. Res., 33: 1677-1688.
9. Hixson, J.E., and Vernier, D.T. (1990) Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J. Lipid. Res., 31: 545-548.
10. Ikeda, T., Suguichi, H, Senba, U., Shibuya, Y., Uji, Y., Okabe, H., and Araki, S. (1993) Preliminary finding on the variation of serum apolipoprotein levels in neuronal degeneration disorders. J. Clin. Lab. Anal., 7: 1-4.
11. Kuusisto, J., Koivisto, K., Mykkänen, L., Helkala, E.L., Vanhanen, M., et al. (1994) Association of apolipoprotein E phenotypes with late onset Alzheimer's disease: population-based study. Br. Med. J., 309: 636-638.
12. Lehtimaki, T., Pirttila, T., Mehta, P.D., Wisniewski, H.M., Frey, H. and Nikkar, T. (1995) Apolipoprotein E (apoE) polymorphism and its influence on apoE concentrations in the cerebrospinal fluid in Finnish patients with Alzheimer's disease. Hum. Genet., 95: 39-42.
13. Lepage, L., Aguillon, D., Cuvelier, I., Schielle, F., Galteau, M.M. and Siest, G. (1986) Etude familiale de quelques modifications génétiques par electrophorèse bidimentionnelle. In Recent Progress in Two-dimensional Electrophoresis (M.M. Galteau, and G. Siest, Eds). Presses Universitaires, Nancy, 141-148.
14. Linton, M.F., Gish, R., Hubl, S.T., Butler, E., Esquivel, C., Bry, W.I., Boyles, J.K., Wardell, M.R. and Young, S.G. (1991) Phenotypes of apolipoprotein A and apolipoprotein E after liver transplantation. J. Clin. Invest., 88: 270-281.
15. Lucotte, G., David, F., Visvikis, S., Leninger-Muller, B., Siest, G. and Barbron, M.C. (1993) Apolipoprotein-E-ε4 allele and Alzheimer's disease. Lancet, 3342: 1309.
16. Lucotte, G., Visvikis, S., Leninger-Muller, B., David, F., Bevriche, S. and Reveilleau, S. (1994) Association of apolipoprotein-E allele ε4 with late-onset sporadic Alzheimer's disease. Am J. Med. Genet., 54: 286-288.
17. Mahley, R.W. (1988) Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology. Science, 240: 622-630.
18. McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., and Stadlan, E.M. (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS/ADRDA. Working Group under the auspices of the Departement of Health and Human Services task force on Alzheimer's disease. Neurology, 34: 939-944.
19. Miller, S.A., Dykes, D.D. and Polesky, S. (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucl. Acids Res., 16: 12-15.
20. Nathan, B.P., Bellestra S., Sanan, D.A., Weisgraber, K.H., Mahley, R.W. and Pitas, R.E. (1994) Differential effects of apolipoproteins E3 et E4 on neuronal Growth in vitro. Science, 264: 850-852.
21. Okinzumi, K., Onodera, O, Namba, Y., Ikeda, K., Yamamato, T., Seki, K., Ueki, A., Nanko, S., Tanaka, H., Takahashi, H., Oyanagi, K., Mizusawa, H., Kanazawa, I. and Tsuji S. (1995) Genetic association of the the very low density lipoprotein (VLDL) receptor gene with sporadic AD. Nature Genet., 11: 207-209.
22. Pirttilä, T., Mehta, P.D., Lehtimaki, T., Kim, K.S., Sersen, E.A., Frey, H., Nikkari, T. and Wisniewski, H.M. (1994) Relationship between apolipoprotein E4 allele and CSF amyloid β-protein in Alzheimer's disease and controls. Neurosci. Res. Commun., 15: 201-207.
23. Pitas, R.E., Boyles, J.K., Lee, S.H., Hui, D. and Weisgraber, K.H. (1987) Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B, E(LDL) receptors in the brain. J. Biol. Chem., 262: 14352-14360.
24. Poirier, J., Baccichet, A., Dea, D. and Gauthier, S. (1993) Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippcampus in adult rats. Neuroscience, 55: 81-90.
25. Rebeck, G.W., Reither, J., Strickland, D.K. and Hyman, B.T. (1993) Apolipoprotein E in sporadic Alzheimer's disease allelic variation and receptor interactions. Neuron, 11: 575-580.
26. Rifai, N., Christenson, R.H., Gelman, B.B., Silverman, L.M., (1987) Changes in cerebrospinal fluid IgG and apolipoprotein E indices in patients with multiple sclerosis during demyelination and remyelination Clin. Chem., 33: 115-1157.
27. Rösler, N., Wichart, I., and Jellinger, K.A. (1996) Intra vitam lumbar cerebrospinal fluid and serum and postmortem ventricular immunoreactive apolipoprotein E in patients with Alzheimer's disease. J. Neurosurg. Psychiatry, 60: 452-454.
28. Schmechel, D.E., Sauders, A.M., Strittmatter, W.J., Crain, B.J., Hulette, C.M., Joo, S.H., Pericak-Vance, M.A., Goldgaber, D. and Roses A.D. (1993) Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer's disease. Proc. Natl. Sci., 90: 9649-9653.
29. Siest, G., Pillot, T., Régis-Bailly, A., Leninger-Muller, B., Steinmetz, J., Galteau, M.M. and Visvikis, S. (1995) Apolipoprotein E: an important gene and protein to follow in laboratory medicine. Clin. Chem., 41: 1068-1086.
30. Strittmatter, W.J., Sauders, A.M., Schmechel, D., Pecicak-Vance, M., Enghild, J., Salvesen, G.S., and Roses, A.D. (1993) ApolipoproteinE: High-avidity biding to β-amyloid and increased frequency of type ε4 allele in late onset familial Alzheimer's disease. Proc. Natl. Acad. Sci., 9: 1977-1981.
31. Tooyama, T., Kawamata, T., Akiyama, H., Moestrup, S.K., Gliemann, J. and McGeer, P.L. (1993) Immunohistochemical study of α2-macroglobulin receptor in Alzheimer and control postmortem human brain. Molec. Chem. Neuropath., 18: 153-160.
32. VanderPutten, D.M., Cameron, B.M. and Merril, C.R. (1993) Increased apolipoprotein-E concentrations in individuals suffering chronic low back syndrome identified by two-dimensional gel electrophoresis. Appl. Theor. Electroph., 3:247-252.
33. Wisniewski, T., Lalowski, M., Golabek, A., Vogel, T. and Frangione, B. (1995) Alzheimer's disease: an apoE amyloidosis? Lancet, 345: 956-958.
34. Yamada, T., Kondo, A., Takamatsu, J-I., Tateishi, J., Goto, I. (1995) Apolipoprotein E mRNA in the brains of patients with Alzheimer's disease. J. Neuro. Sci., 129: 56-61.
35. Yoshizawa, T., Yamakawa-Kobayashi, K., Komatsuzaki, Y., Arimani, T., Oguni, E., Mizusawa, H., et al. (1994) Dose-dependent association of apolipoprotein E allele ε4 with late onset, sporadic Alzheimer's disease. Ann. Neurol., 36: 656-659.
36. Zlokovic, B.V., Martel C.L., Mackic J.B., Matsubara E., Wisniewski T., McComb G., Frangione B. and Ghiso J. (1994) Brain uptake of ciculating apolipoprotein J and E complexed to Alzheimer's amyloid β. Biochem. Biophys. Res. Commun., 205: 1431-1437.