Modulation of the age at onset of Parkinson's disease by apolipoprotein E genotypes

Annals of Neurology

Volumn 42, Issue 4, 1997, Pages 655-658

  Zareparsi, Sepideh ^a   Kaye, Jeffrey ^a,b   Camicioli, Richard ^a   Grimslid, Holly ^a   Oken, Barry ^a   Litt, Michael ^a   Nutt, John ^a   Bird, Thomas ^c,e   Schellenberg, Gerard ^d,e,f   Payami, Haydeh ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b PORTLAND VA MEDICAL CENTER   (United States)

^c Neurology Section   (United States)

^d Geriatric Research Education and Clinical Center   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

^f UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4;

ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; FEMALE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PARKINSON DISEASE; PRIORITY JOURNAL; RISK ASSESSMENT;

AGE OF ONSET; AGED; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE;

EID: 0030881644     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410420417     Document Type: Article

References (24)

1. Tanner C. Epidemiology of Parkinson's disease. Parkinsons Dis 1992;10:317-329
2. Katzman R, Kawas C. The epidemiology of dementia and Alzheimer disease. In: Terry RD, ed. Alzheimer disease. New York: Raven Press, 1994:105-122
3. Tison F, Dartigues JF, Auriocombe S, et al. Dementia in Parkinson's disease: a population-based study in ambulatory and institutionalized individuals. Neurology 1995;45:705-708
4. Marder K, Tang M-X, Cote L, et al. The frequency and associated risk factors for dementia in patients with Parkinson's disease. Arch Neurol 1995;52:695-701
5. Funkenstein HH, Albert MS, Cook NR, et al. Extrapyramidal signs and other neurologic findings in clinically diagnosed Alzheimer's disease. Arch Neurol 1993;50:51-56
6. Merello M, Sabe L, Teson A, et al. Extrapyramidalism in Alzheimer's disease: prevalence, psychiatric, and neuropsychological correlates. J Neurol Neurosurg Psychiatry 1994;57:1503-1509
7. Hulette C, Mirra S, Wilkinson W, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part IX. A prospective cliniconeuropathologic study of Parkinson's features in Alzheimer's disease. Neurology 1995;45:1991-1995
8. Hughes AJ, Daniel SE, Blankson S, Lees AJ. A clinicopathologic study of 100 cases of Parkinson's disease. Arch Neurol 1993;50:140-148
9. Hofman A, Schulte W, Tanja TA, et al. History of dementia and Parkinson's disease in 1st-degree relatives of patients with Alzheimer's disease. Neurology 1989;39:1589-1592
10. Schellenberg G. Genetic dissection of Alzheimer disease, a heterogeneous disorder. Proc Natl Acad Sci USA 1995;92:8552-8559
11. Payami H, Grimslid H, Oken B, et al. A prospective study of cognitive health in the elderly (Oregon Brain Aging Study): effects of family history and apolipoprotein E genotype. Am J Hum Genet 1997;60:948-956
12. Lazzarini AM, Myers RH, Zimmerman TR, et al. A clinical genetic study of Parkinson's disease: evidence for dominant transmission. Neurology 1994;44:499-506
13. Payami H, Larsen K, Bernard S, Nutt J. Increased risk of Parkinson disease in parents and siblings of patients. Ann Neurol 1994;36:659-661
14. Polymeropoulos MH, Higgins JJ, Golbe LI, et al. Mapping of a gene for Parkinson's disease to chromosome 4q21-q23. Science 1996;274:1197-1199
15. Payami H, Bernard S, Larsen K, et al. Genetic anticipation in Parkinson disease. Neurology 1995;45:135-138
16. Arai H, Muramatsu T, Higuchi S, et al. Apolipoprotein E gene in Parkinson's disease with or without dementia. Lancet 1994; 344:889
17. Marder K, Maestre G, Cote L, et al. The apolipoprotein ε4 allele in Patkinson's disease with and without dementia. Neurology 1994;44:1330-1331
18. Rubinsztein D, Hanlon CS, Irving RM, et al. ApoE genotypes in multiple sclerosis, Parkinson's disease, schwannomas and late-onset Alzheimer's disease. Mol Cell Probes 1994;8:519-525
19. Koller W, Glatt S, Hubble J, et al. Apolipoprotein E genotypes in Parkinson's disease with and without dementia. Ann Neurol 1995;37:242-245
20. Whitehead AS, Bertrandy S, Finnan F, et al. Frequency of the apolipoprotein E ε4 allele in a case-control study of early onset Parkinson's disease. J Neurol Neurosurg Psychiatry 1996;61: 347-351
21. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hha I. J Lipid Res 1990;31:545-548
22. Rebeck G, Perls T, West H, et al. Reduced apolipoprotein ε4 allele frequency in the oldest old Alzheimer's patients and cognitively normal individuals. Neurology 1994;44:1513-1516
23. Corder EH, Saunders AM, Strittmatter AM, et al. Apolipoprotein E, survival in Alzheimer's disease patients, and the competing risks of death and Alzheimer's disease. Neurology 1995;45: 1323-1328
24. Sobel E, Louhija J, Sulkava R, et al. Lack of association of apolipoprotein E allele ε4 with late-onset Alzheimer's disease among Finnish centenarians. Neurology 1995;45:903-907