Both hydroxylamine and nitroxide protect cardiomyocytes from oxidative stress

Free Radical Biology and Medicine

Volumn 24, Issue 1, 1998, Pages 66-75

  Zhang, Renliang ^a   Pinson, Arie ^a   Samuni, Amram ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

Anti oxidants; Free radicals; Hydrogen peroxide; Oxidative stress; Superoxide; Superoxide dismutase; Xanthine oxidase

Indexed keywords

ADENOSINE TRIPHOSPHATE; HYDROGEN PEROXIDE; HYDROXYLAMINE; HYPOXANTHINE; LACTATE DEHYDROGENASE; NITROXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TEMPOL; TEMPONE; XANTHINE OXIDASE;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; HEART MUSCLE CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; CYCLIC N-OXIDES; FREE RADICALS; HEART; MYOCARDIUM; NITROGEN OXIDES; OXIDATIVE STRESS; PIPERIDINES; RATS;

ANIMALIA;

EID: 0031962667     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00165-2     Document Type: Article

References (36)

1. Bolli R. Oxygen-derived free radicals and postischemic myocardial dysfunction ("stunned myocardium"). J. Am. Coll. Cardiol. 12:1988;239-249.
2. Janero D. R., Hreniuk D., Sharif H. M. Hydrogen peroxide-induced oxidative stress to the mammalian heart-muscle cell (cardiomyocyte): Lethal peroxidative membrane injury. J. Cell. Physiol. 149:1991;347-364.
3. Grill H. P., Zweier J. L., Kuppusamy P., Weisfeldt M. L., Flaherty J. T. Direct measurement of myocardial free radical generation in an in vivo model: Effects of postischemic reperfusion and treatment with human recombinant superoxide dismutase. J. Am. Cell. Cardiol. 20:1992;1604-1611.
4. Janero D. R., Hreniuk D., Sharif H. M. Hydroperoxide-induced oxidative stress impairs heart muscle cell carbohydrate metabolism. Am. J. Physiol. 266:1994;C179-C188.
5. Hearse D. J., Manning A. S., Downey J. M., Yellon D. M. Xanthine oxidase: A critical mediator of myocardial injury during ischemia and reperfusion? Acta Physiol. Scand. Suppl. 548:1986;65-78.
6. Shlafer M., Kane P. F., Kirsh M. M. Superoxide dismutase plus catalase enhance the efficacy of hypothermic cardioplegia to protect the globally ischemic, reperfused heart. J. Thorac. Cardiovasc. Surg. 83:1982;830-839.
7. Zweier J. L, Rayburn B. K., Flaherty J. T., Weisfeldt M. L. Recombinant superoxide dismutase reduces oxygen free radical concentrations in reperfused myocardium. J. Clin. Invest. 80:1987;1728-1734.
8. Williams R. E., Zweier J. L., Flaherty J. T. Treatment with deferoxamine during ischemia improves functional and metabolic recovery and reduces reperfusion-induced oxygen radical generation in rabbit hearts. Circulation. 83:1991;1006-1014.
9. Katoh S., Toyama J., Itsuo K., Toshiaki A., Abe T. Deferoxamine, an iron chelator, reduces myocardial injury and free radical generation in isolated neonatal rabbit hearts subjected to global ischemia-reperfusion. J. Mol. Cell. Cardiol. 24:1992;1267-1275.
10. Halliwell B., Gutteridge J. M. C. The chemistry of oxygen radicals and other oxygen-derived species. Free radicals in biology and medicine. 1985;20-64 Clarendon Press, Oxford.
11. Chambers D. J., Braimbridge M. V., Hearse D. J. Free radicals and cardioplegia. Free radical scavengers improve postischemic function of rat myocardium. Eur. J. Cardiothorac. Surg. 1:1987;37-45.
12. Engler R., Covell J. W. Granulocytes cause reperfusion ventricular dysfunction after 15 minute ischemia in the dog. Circ. Res. 61:1987;20-28.
13. Ankel E. G., Lai C. S., Hopwood L. E., Zivkovic Z. Cytotoxicity of commonly used nitroxide radical spin probes. Life Sci. 40:1987;495-498.
14. Froncisz W., Lai C. S., Hyde J. S. Spin-label oximetry: kinetic study of cell respiration using a rapid-passage T1-sensitive electron spin resonance display. Proc. Natl. Acad. Sci. USA. 82:1985;411-415.
15. Swartz H. M., Chen K., Hu H. P., Hideg K. Contrast agents for magnetic resonance spectroscopy: A method to obtain increased information in in vivo and in vitro spectroscopy. Magn. Reson. Med. 22:1991;372-377.
16. Samuni A., Krishna C. M., Riesz P., Finkelstein E., Russo A. A novel metal-free low molecular weight superoxide dismutase mimic. J. Biol. Chem. 263:1988;17921-17924.
17. Krishna M. C., Samuni A. Nitroxides as antioxidants. Methods Enzymol. 234:1994;580-589.
18. ̇- or as SOD mimics? J. Biol. Chem. 271:1996;26026-26031.
19. Mitchell J. B., Samuni A., Krishna M. C., DeGraff W. G., Ahn M. S., Samuni U., Russo A. Biologically active metal-independent superoxide dismutase mimics. Biochemistry. 29:1990;2802-2807.
20. Mitchell J. B., DeGraff W., Kaufman D., Krishna M. C., Samuni A., Finkelstein E., Ahn M. S., Hahn S. M., Gamson J., Russo A. Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol. Arch. Biochem. Biophys. 289:1991;62-70.
21. Samuni A., Winkelsberg D., Pinson A., Hahn S. M., Mitchell J. B., Russo A. Nitroxide stable radicals protect beating cardiomyocytes against oxidative damage. J. Clin. Invest. 87:1991;1526-1530.
22. Mohsen M., Pinson A., Zhang R., Samuni A. Do nitroxides protect cardiomyocytes from hydrogen peroxide or superoxide? Mol. Cell. Biochem. 145:1995;103-110.
23. Gelvan D., Saltman P., Powell S. R. Cardiac reperfusion damage prevented by a nitroxide free radical. Proc. Natl. Acad. Sci. USA. 88:1991;4680-4684.
24. Nilsson U. A., Olsson L. I., Carlin G., Bylund F. A. Inhibition of lipid peroxidation by spin labels. Relationships between structure and function. J. Biol. Chem. 264:1989;11131-11135.
25. Nilsson U. A., Olsson L., Thor H., Moldeus P., Bylund-Fellenius A. Detection of oxygen radicals during reperfusion of intestinal cells in vitro. Free Radic. Biol. Med. 6:1989;251-259.
26. Komarov P. G., Morgunov A. A., Bilenko M. V., Zhdanov R. I. Anti-ischemic effect of 1-hydroxy derivatives of nitroxyl bioantioxidants. Zhdanov R. I. Bioactive spin labels. 1992;491-508 Springer-Verlag.
27. Pinson A., Padieu P., Harari I. Techniques for culturing heart cells. 1987;CRC Press Inc, Boca Raton.
28. Wroblewski F., LaDue J. S. Lactic dehydrogenase activity in blood. Proc. Soc. Exp. Biol. Med. 90:1955;210-213.
29. Holmsen H., Storm E., Day H. J. Determination of ATP and ADP in blood platelets-modification of firefly luciferase assay for plasma. Anal. Bioch. 46:1972;489-509.
30. Beresewicz A., Horackova M. Alterations in electrical and contractile behavior of isolated cardiomyocytes by hydrogen peroxide: possible ionic mechanisms. J. Mol. Cell. Cardiol. 23:1991;899-918.
31. Nilsson U. A., Carlin G., Bylund F. A. The hydroxylamine OXANOH and its reaction product, the nitroxide OXANO., act as complementary inhibitors of lipid peroxidation. Chem. Biol. Interact. 74:1990;325-342.
32. Samuni A., Krishna C. M., Riesz P., Finkelstein E., Russo A. Superoxide reaction with nitroxide spin-adducts. Free Radic. Biol. Med. 6:1989;141-148.
33. Samuni A., Mitchell J. B., DeGraff W., Krishna C. M., Samuni U., Russo A. Nitroxide SOD-mimics: modes of action. Free Radic. Res. Commun. 1:1991;187-194.
34. Samuni A., Godinger D., Aronovitch J., Russo A., Mitchell J. B. Nitroxides block DNA scission and protect cells from oxidative damage. Biochemistry. 30:1991;555-561.
35. Chateauneuf J., Lusztyk J., Ingold K. Absolute rate constants for the reactions of some carbon-centered radicals with 2,2,6,6-tetramethylpiperidine-N-oxyl. J. Org. Chem. 53:1988;1629-1632.
36. Takemura G., Onodera T., Millard R. W., Ashraf M. Demonstration of hydroxyl radical and its role in hydrogen peroxide-induced myocardial injury: hydroxyl radical dependent and independent mechanisms. Free Rad. Biol. Med. 15:1993;13-25.