-
1
-
-
0035296582
-
Genetics of type 2 diabetes: Insight from targeted mouse mutants
-
Accili D, Kido Y, Nakae J, Lauro D, Park BC 2001 Genetics of type 2 diabetes: insight from targeted mouse mutants. Curr Mol Med 1:9-23
-
(2001)
Curr Mol Med
, vol.1
, pp. 9-23
-
-
Accili, D.1
Kido, Y.2
Nakae, J.3
Lauro, D.4
Park, B.C.5
-
2
-
-
0027716955
-
Structure, expression, and regulation of the IGF-I gene
-
Adamo ML, Neuenschwander S, LeRoith D, Roberts CT Jr 1993 Structure, expression, and regulation of the IGF-I gene. Adv Exp Med Biol 343:1-11
-
(1993)
Adv Exp Med Biol
, vol.343
, pp. 1-11
-
-
Adamo, M.L.1
Neuenschwander, S.2
LeRoith, D.3
Roberts Jr, C.T.4
-
3
-
-
23844551318
-
Minireview: Role of the growth hormone/insulin-like growth factor system in mammalian aging
-
Bartke A 2005 Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging. Endocrinology 146:3718-3723
-
(2005)
Endocrinology
, vol.146
, pp. 3718-3723
-
-
Bartke, A.1
-
4
-
-
0035499454
-
Ten years of protein kinase B signalling: A hard Akt to follow
-
Brazil DP, Hemmings BA 2001 Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem Sci 26:657-664
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 657-664
-
-
Brazil, D.P.1
Hemmings, B.A.2
-
5
-
-
0032559272
-
Plasma insulin-like growth factor-I and prostate cancer risk: A prospective study
-
Chan JM, Stampfer MJ, Giovannucci E et al 1998 Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science 279:563-566
-
(1998)
Science
, vol.279
, pp. 563-566
-
-
Chan, J.M.1
Stampfer, M.J.2
Giovannucci, E.3
-
6
-
-
0033228631
-
Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice
-
Delaughter MC, Taffet GE, Fiorotto ML, Entman ML, Schwartz RJ 1999 Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice. Faseb J 13:1923-1929
-
(1999)
Faseb J
, vol.13
, pp. 1923-1929
-
-
Delaughter, M.C.1
Taffet, G.E.2
Fiorotto, M.L.3
Entman, M.L.4
Schwartz, R.J.5
-
7
-
-
0033604521
-
Ribosomal S6 kinase signalling and the control of translation
-
Dufner A, Thomas G 1999 Ribosomal S6 kinase signalling and the control of translation. Exp Cell Res 253:100-109
-
(1999)
Exp Cell Res
, vol.253
, pp. 100-109
-
-
Dufner, A.1
Thomas, G.2
-
8
-
-
0034072020
-
The role of the GH-IGF-I axis in the regulation of myocardial growth: From experimental models to human evidence
-
Fazio S, Palmieri EA, Biondi B, Cittadini A, Sacca L 2000 The role of the GH-IGF-I axis in the regulation of myocardial growth: from experimental models to human evidence. Eur J Endocrinol 142:211-216
-
(2000)
Eur J Endocrinol
, vol.142
, pp. 211-216
-
-
Fazio, S.1
Palmieri, E.A.2
Biondi, B.3
Cittadini, A.4
Sacca, L.5
-
9
-
-
0037318822
-
Signalling pathways that mediate skeletal muscle hypertrophy and atrophy
-
Glass DJ 2003 Signalling pathways that mediate skeletal muscle hypertrophy and atrophy. Nat Cell Biol 5:87-90
-
(2003)
Nat Cell Biol
, vol.5
, pp. 87-90
-
-
Glass, D.J.1
-
10
-
-
11144355021
-
-
Hertweck M, Gobel C, Baumeister R 2004 C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span. Dev Cell 6:577-588
-
Hertweck M, Gobel C, Baumeister R 2004 C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span. Dev Cell 6:577-588
-
-
-
-
11
-
-
0038385981
-
Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage
-
Hill M, Goldspink G 2003 Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage. J Physiol 549(Pt 2):409-418
-
(2003)
J Physiol
, vol.549
, Issue.PART 2
, pp. 409-418
-
-
Hill, M.1
Goldspink, G.2
-
12
-
-
0027955344
-
Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action
-
Kato H, Faria TN, Stannard B, Roberts CT Jr, LeRoith D 1994 Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action. Mol Endocrinol 8:40-50
-
(1994)
Mol Endocrinol
, vol.8
, pp. 40-50
-
-
Kato, H.1
Faria, T.N.2
Stannard, B.3
Roberts Jr, C.T.4
LeRoith, D.5
-
13
-
-
0034727895
-
Caspase-9: Involvement in secondary death of axotomized rat retinal ganglion cells in vivo
-
Kermer P, Ankerhold R, Klocker N, Krajewski S, Reed JC, Bahr M 2000 Caspase-9: involvement in secondary death of axotomized rat retinal ganglion cells in vivo. Brain Res Mol Brain Res 85:144-150
-
(2000)
Brain Res Mol Brain Res
, vol.85
, pp. 144-150
-
-
Kermer, P.1
Ankerhold, R.2
Klocker, N.3
Krajewski, S.4
Reed, J.C.5
Bahr, M.6
-
14
-
-
0037458622
-
Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells
-
Leong ML, Maiyar AC, Kim B, O'Keeffe BA, Firestone GL 2003 Expression of the serum- and glucocorticoid-inducible protein kinase, Sgk, is a cell survival response to multiple types of environmental stress stimuli in mammary epithelial cells. J Biol Chem 278:5871-5882
-
(2003)
J Biol Chem
, vol.278
, pp. 5871-5882
-
-
Leong, M.L.1
Maiyar, A.C.2
Kim, B.3
O'Keeffe, B.A.4
Firestone, G.L.5
-
15
-
-
0030829808
-
Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy
-
Li Q, Li B, Wang X et al 1997 Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest 100:1991-1999
-
(1997)
J Clin Invest
, vol.100
, pp. 1991-1999
-
-
Li, Q.1
Li, B.2
Wang, X.3
-
16
-
-
0034121872
-
Fetal wound repair results in scar formation in interleukin-10-deficient mice in a syngeneic murine model of scarless fetal wound repair
-
discussion 872-863
-
Liechty KW, Kim HB, Adzick NS, Crombleholme TM 2000 Fetal wound repair results in scar formation in interleukin-10-deficient mice in a syngeneic murine model of scarless fetal wound repair. J Pediatr Surg 35:866-872; discussion 872-863
-
(2000)
J Pediatr Surg
, vol.35
, pp. 866-872
-
-
Liechty, K.W.1
Kim, H.B.2
Adzick, N.S.3
Crombleholme, T.M.4
-
17
-
-
0037015269
-
TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation
-
Long X, Spycher C, Han ZS, Rose AM, Muller F, Avruch J 2002 TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation. Curr Biol 12:1448-1461
-
(2002)
Curr Biol
, vol.12
, pp. 1448-1461
-
-
Long, X.1
Spycher, C.2
Han, Z.S.3
Rose, A.M.4
Muller, F.5
Avruch, J.6
-
18
-
-
0037470488
-
Evolutionary medicine: From dwarf model systems to healthy centenarians?
-
Longo VD, Finch CE 2003 Evolutionary medicine: from dwarf model systems to healthy centenarians? Science 299:1342-1346
-
(2003)
Science
, vol.299
, pp. 1342-1346
-
-
Longo, V.D.1
Finch, C.E.2
-
19
-
-
0033560860
-
Expression of insulin growth factor-1 splice variants and structural genes in rabbit skeletal muscle induced by stretch and stimulation
-
McKoy G, Ashley W, Mander J et al 1999 Expression of insulin growth factor-1 splice variants and structural genes in rabbit skeletal muscle induced by stretch and stimulation. J Physiol 516:583-592
-
(1999)
J Physiol
, vol.516
, pp. 583-592
-
-
McKoy, G.1
Ashley, W.2
Mander, J.3
-
20
-
-
24744449943
-
IGF-1, inflammation and stem cells: Interactions during muscle regeneration
-
Mourkioti F, Rosenthal N 2005 IGF-1, inflammation and stem cells: interactions during muscle regeneration. Trends Immunol 26:535-542
-
(2005)
Trends Immunol
, vol.26
, pp. 535-542
-
-
Mourkioti, F.1
Rosenthal, N.2
-
21
-
-
0037457059
-
IGF-1 activates p21 to inhibit UV-induced cell death
-
Murray SA, Zheng H, Gu L, Jim Xiao ZX 2003 IGF-1 activates p21 to inhibit UV-induced cell death. Oncogene 22:1703-1711
-
(2003)
Oncogene
, vol.22
, pp. 1703-1711
-
-
Murray, S.A.1
Zheng, H.2
Gu, L.3
Jim Xiao, Z.X.4
-
23
-
-
0036713481
-
The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels
-
Oldham S, Stocker H, Laffargue M, Wittwer F, Wymann M, Hafen E 2002 The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels. Development 129:4103-4109
-
(2002)
Development
, vol.129
, pp. 4103-4109
-
-
Oldham, S.1
Stocker, H.2
Laffargue, M.3
Wittwer, F.4
Wymann, M.5
Hafen, E.6
-
24
-
-
0037438376
-
IL-6 and matrix metalloproteinase-1 are regulated by the cyclin-dependent kinase inhibitor p21 in synovial fibroblasts
-
Perlman H, Bradley K, Liu H et al 2003 IL-6 and matrix metalloproteinase-1 are regulated by the cyclin-dependent kinase inhibitor p21 in synovial fibroblasts. J Immunol 170: 838-845
-
(2003)
J Immunol
, vol.170
, pp. 838-845
-
-
Perlman, H.1
Bradley, K.2
Liu, H.3
-
26
-
-
0035353691
-
Cellular therapy reverses myocardial dysfunction
-
Rajnoch C, Chachques JC, Berrebi A, Bruneval P, Benoit MO, Carpentier A 2001 Cellular therapy reverses myocardial dysfunction. J Thorac Cardiovasc Surg 121:871-878
-
(2001)
J Thorac Cardiovasc Surg
, vol.121
, pp. 871-878
-
-
Rajnoch, C.1
Chachques, J.C.2
Berrebi, A.3
Bruneval, P.4
Benoit, M.O.5
Carpentier, A.6
-
27
-
-
9444269796
-
Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice
-
Reiss K, Cheng W, Ferber A et al 1996 Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice. Proc Natl Acad Sci USA 93:8630-8635
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8630-8635
-
-
Reiss, K.1
Cheng, W.2
Ferber, A.3
-
29
-
-
0035735902
-
Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways
-
Rommel C, Bodine SC, Clarke BA et al 2001 Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways. Nat Cell Biol 3: 1009-1013
-
(2001)
Nat Cell Biol
, vol.3
, pp. 1009-1013
-
-
Rommel, C.1
Bodine, S.C.2
Clarke, B.A.3
-
30
-
-
0036348144
-
Gene therapy for cardiac cachexia?
-
Rosenthal N, Musaro A 2002 Gene therapy for cardiac cachexia? Int J Cardiol 85:185-191
-
(2002)
Int J Cardiol
, vol.85
, pp. 185-191
-
-
Rosenthal, N.1
Musaro, A.2
-
31
-
-
0037155824
-
Glycogen synthase kinase-3 couples AKT-dependent signalling to the regulation of p21Cip1 degradation
-
Rossig L, Badorff C, Holzmann Y, Zeiher AM, Dimmeler S 2002 Glycogen synthase kinase-3 couples AKT-dependent signalling to the regulation of p21Cip1 degradation. J Biol Chem 277:9684-9689
-
(2002)
J Biol Chem
, vol.277
, pp. 9684-9689
-
-
Rossig, L.1
Badorff, C.2
Holzmann, Y.3
Zeiher, A.M.4
Dimmeler, S.5
-
32
-
-
0032504257
-
Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes
-
Rother KI, Imai Y, Caruso M, Beguinot F, Formisano P, Accili D 1998 Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes. J Biol Chem 273: 17491-17497
-
(1998)
J Biol Chem
, vol.273
, pp. 17491-17497
-
-
Rother, K.I.1
Imai, Y.2
Caruso, M.3
Beguinot, F.4
Formisano, P.5
Accili, D.6
-
33
-
-
0034644525
-
TOR, a central controller of cell growth
-
Schmelzle T, Hall MN 2000 TOR, a central controller of cell growth. Cell 103:253-262
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
34
-
-
13544266474
-
Reconciling data from transgenic mice that overexpress IGF-I specifically in skeletal muscle
-
Shavlakadze T, Winn N, Rosenthal N, Grounds MD 2005 Reconciling data from transgenic mice that overexpress IGF-I specifically in skeletal muscle. Growth Horm IGF Res 15: 4-18
-
(2005)
Growth Horm IGF Res
, vol.15
, pp. 4-18
-
-
Shavlakadze, T.1
Winn, N.2
Rosenthal, N.3
Grounds, M.D.4
-
35
-
-
0034213075
-
The conserved phosphoinositide 3-kinase pathway determines heart size in mice
-
Shioi T, Kang PM, Douglas PS et al 2000 The conserved phosphoinositide 3-kinase pathway determines heart size in mice. EMBO J 19:2537-2548
-
(2000)
EMBO J
, vol.19
, pp. 2537-2548
-
-
Shioi, T.1
Kang, P.M.2
Douglas, P.S.3
-
36
-
-
2042425906
-
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
-
Stitt TN, Drujan D, Clarke BA et al 2004 The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell 14:395-403
-
(2004)
Mol Cell
, vol.14
, pp. 395-403
-
-
Stitt, T.N.1
Drujan, D.2
Clarke, B.A.3
-
39
-
-
0038123186
-
Insulin-like growth factor isoforms in skeletal muscle aging, regeneration, and disease
-
Winn N, Paul A, Musaro A, Rosenthal N 2002 Insulin-like growth factor isoforms in skeletal muscle aging, regeneration, and disease. Cold Spring Harb Symp Quant Biol 67:507-518
-
(2002)
Cold Spring Harb Symp Quant Biol
, vol.67
, pp. 507-518
-
-
Winn, N.1
Paul, A.2
Musaro, A.3
Rosenthal, N.4
|