Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy

Journal of Clinical Investigation

Volumn 100, Issue 8, 1997, Pages 1991-1999

  Li, Qiong ^a   Li, Baosheng ^a   Wang, Xiaowei ^a   Leri, Annarosa ^a   Jana, Kumar P ^a   Liu, Yu ^a   Kajstura, Jan ^a   Baserga, Renato ^b   Anversa, Piero ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Apoptotic and necrotic myocyte cell death; Heart failure; IGF 1 in myocytes; Myocardial loading; Ventricular remodeling

Indexed keywords

SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CORONARY ARTERY LIGATION; HEART DILATATION; HEART HYPERTROPHY; HEART INFARCTION; HEART PROTECTION; HEART VENTRICLE WALL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRESS;

EID: 0030829808     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119730     Document Type: Article

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