Insulin-like growth factor isoforms in skeletal muscle aging, regeneration, and disease

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 67, Issue , 2002, Pages 507-518

  Winn, N ^a   Paul, A ^a   Musaro A ^b   Rosenthal, N ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; SOMATOMEDIN; SOMATOMEDIN C;

AGING; CONFERENCE PAPER; GENE EXPRESSION; MUSCLE DISEASE; MUSCLE REGENERATION; NONHUMAN; POSTNATAL GROWTH; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN METABOLISM; SKELETAL MUSCLE; TRANSGENE; ARTICLE; GENE FUNCTION; GENETIC TRANSCRIPTION; HUMAN; IN VIVO STUDY; MYOPATHY;

EID: 0038123186     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2002.67.507     Document Type: Conference Paper

References (71)

1. Adamo M.L. 1995. Regulation of insulin-like growth factor I gene expression. Diabetes Rev. 3: 2.
2. Adamo M., Lowe W.L., Jr., LeRoith D., and Roberts C.T., Jr. 1989. Insulin-like growth factor I messenger ribonucleic acids with alternative 5′-untranslated regions are differentially expressed during development of the rat. Endocrinology 124: 2737.
3. Bartke A. 1999. Role of growth hormone and prolactin in the control of reproduction: What are we learning from transgenic and knock-out animals? Steroids 64: 598.
4. Barton E.R., Morris L., Musaró A., Rosenthal N., and Sweeney H.L. 2002. Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice. J. Cell Biol. 157: 137.
5. Barton-Davis E.R., Shoturma D.I., and Sweeney H.L. 1999. Contribution of satellite cells to IGF-I induced hypertrophy of skeletal muscle. Acta Physiol. Scand. 167: 301.
6. Bol D.K., Kiguchi K., Gimenez-Conti I., Rupp T., and DiGiovanni J. 1997. Overexpression of insulin-like growth factor-I induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice. Oncogene 14: 1725.
7. Borchelt D.R., Lee M.K., Slunt H.S., Guarnieri M., Xu Z.S., Wong P.C., Brown R.H., Jr., Price D.L., Sisodia S.S., and Cleveland D.W. 1994. Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity. Proc. Natl. Acad. Sci. 91: 8292.
8. Bucci C., Mallucci P., Roberts C.T., Frunzio R., and Bruni C.B. 1989. Nucleotide sequence of a genomic fragment of the rat IGF-I gene spanning an alternate 5′ non coding exon. Nucleic Acids Res. 17: 3596.
9. Bulfield G., Siller W.G., Wight P.A., and Moore K.J. 1984. X chromosome-linked muscular dystrophy (mdx) in the mouse. Proc. Natl. Acad. Sci. 81: 1189.
10. Carro E., Trejo J.L., Busiguina S., and Torres-Aleman I. 2001. Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy. J. Neurosci. 21: 5678.
11. Chakravarthy M.V., Fiorotto M.L., Schwartz R.J., and Booth F.W. 2001. Long-term insulin-like growth factor-I expression in skeletal muscles attenuates the enhanced in vitro proliferation ability of the resident satellite cells in transgenic mice. Mech. Ageing Dev. 122: 1303.
12. Clark R. 1997. The somatogenic hormones and insulin-like growth factor-I: Stimulators of lymphopoiesis and immune function. Endocr. Rev. 18: 157.
13. Cleveland D.W. 1999. From Charcot to SOD1: Mechanisms of selective motor neuron death in ALS. Neuron 24: 515.
14. Coleman M., DeMayo F., Yin K.C., Lee H.M., Geske R., Montgomery C., and Schwartz R.J. 1995. Myogenic vector expression of insulin-like growth factor I stimulate myocyte differentiation and myofiber hypertrophy in transgenic mice. J. Biol. Chem. 270: 12109.
15. Criswell D.S., Booth F.W., DeMayo F., Schwartz R.J., Gordon S.E., and Fiorotto M.L. 1998. Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophy. Am. J. Physiol. 275: E373.
16. Daughaday W.H., Hall K., Raben M.S., Salmon W.D., Jr., van den Brande J.L., and Van Wyk J.J. 1972. Somatomedin: Proposed designation for sulphation factor. Nature 235: 107.
17. Delaughter M.C., Taffet G.E., Fiorotto M.L., Entman M.L., and Schwartz R.J. 1999. Local insulin-like growth factor I expression induces physiologic, then pathologic cardiac hypertrophy in transgenic mice. FASEB J. 13: 1923.
18. De Luca A., Pierno S., Camerino C., Cocchi D., and Camerino D.C. 1999. Higher content of insulin-like growth factor-I in dystrophic mdx mouse: Potential role in the spontaneous regeneration through an electrophysiological investigation of muscle function. Neuromuscul. Disord. 9: 11.
19. Dentremont K.D., Ye P., D'Ercole A.J., and O'Kusky J.R. 1999. Increased insulin-like growth factor-I (IGF-I) expression during early postnatal development differentially increases neuron number and growth in medullary nuclei of the mouse. Brain Res. Dev. Brain Res. 114: 135.
20. D'Ercole A.J. 1999. Actions of IGF system proteins from studies of transgenic and gene knockout models. In The IGF system (ed. R. Rosenfeld and C.T. Roberts, Jr.), p. 545. Humana Press, Totowa, New Jersey.
21. D'Ercole A.J., Applewhite G., and Underwood L. 1980. Evidence that sometomedin is synthesized by multiple tissues in the fetus. Dev. Biol. 75: 315.
22. Dyck M.K., Parlow A.F., Senechal J.F., Sirard M.A., and Pothier F. 2001. Ovarian expression of human insulin-like growth factor-I in transgenic mice results in cyst formation. Mol. Reprod. Dev. 59: 178.
23. Dyck M.K., Ouellet M., Gagn M., Petitclerc D., Sirard M.A., and Pothier F. 1999. Testes-specific transgene expression in insulin-like growth factor-I transgenic mice. Mol. Reprod. Dev. 54: 32.
24. Engert J., Berglund E.B., and Rosenthal N. 1996. Proliferation precedes differentiation in IGF-I stimulated myogenesis. J. Cell Biol. 135: 431.
25. Ervasti J.M. and Campbell K.P. 1993. A role for the dystrophinglycoprotein complex as a transmembrane linker between laminin and actin. J. Cell Biol. 122: 809.
26. Florini J.R. and Ewton D.Z. 1990. Highly specific inhibition of IGF-I-stimulated differentiation by an antisense oligodeoxyribonucleotide to myogenin mRNA. No effects on other actions of IGF-T. J. Biol. Chem. 265: 13435.
27. Florini J.R., Ewton D.Z., and Coolican S.A. 1996. Growth hormone and the insulin-like growth factor system in myogenesis. Endocr. Rev. 17: 481.
28. Florini J.R., Ewton D.Z., and Magri K.A. 1991. Hormones, growth factors, and myogenic differentiation. Annu. Rev. Physiol. 53: 201.
29. Fryburg D.A. 1994. Insulin-like growth factor I exerts growth hormone- and insulin-like actions on human muscle protein metabolism. Am. J. Physiol. 267: E331.
30. Gao W.Q., Shinsky N., Ingle G., Beck K., Elias K.A., and Powell-Braxton L. 1999. IGF-I deficient mice show reduced peripheral nerve conduction velocities and decreased axonal diameters and respond to exogenous IGF-I treatment. J. Neurobiol. 39: 142.
31. Goldspink G., Yang S.Y., Skarli M., and Vrbova G. 1996. Local growth regulation is associated with an isoform of IGF-1 that is expressed in normal but not in dystrophic muscle when subjected to stretch. J. Physiol. 495P: 162.
32. Gurney M.E., Pu H., Chiu A.Y., Dal Canto M.C., Polchow C.Y., Alexander D.D., Caliendo J., Hentati A., Kwon Y.W., and Deng H.X., et al. 1994. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 264: 1772.
33. Hoyt E., Van Wyk J.J., and Lund P.K. 1988. Tissue and development specific regulation of a complex family of rat insulin-like growth factor I messenger ribonucleic acids. Mol. Endocrinol. 2: 1077.
34. Julien J.P. 2001. Amyotrophic lateral sclerosis. Unfolding the toxicity of the misfolded. Cell 104: 581.
35. Kajstura J., Fiordaliso F., Andreoli A.M., Li B., Chimenti S., Medow M.S., Limana F., Nadal-Ginard B., Leri A., and Anversa P. 2001. IGF-1 overexpression inhibits the development of diabetic cardiomyopathy and angiotensin II-mediated oxidative stress. Diabetes 50: 1414.
36. Lee K.H., Calikoglu A.S., Ye P., and D'Ercole A.J. 1999. Insulin-like growth factor-I (IGF-I) ameliorates and IGF binding protein-1 (IGFBP-1) exacerbates the effects of undernutrition on brain growth during early postnatal life: Studies in IGF-I and IGFBP-1 transgenic mice. Pediatr. Res. 45: 331.
37. Leri A., Liu Y., Wang X., Kajstura J., Malhotra A., Meggs L.G., and Anversa P. 1999. Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice. Circ. Res. 84: 752.
38. LeRoith D. and Roberts C.T., Jr. 1991. Insulin-like growth factor I (IGF-1): A molecular basis for endocrine versus local action. Mol. Cell. Endocrinol. 77: C57.
39. LeRoith D., Bondy C., Yakar S., Liu J.L., and Butler A. 2001. The somatomedin hypothesis: 2001. Endocr. Rev. 22: 53.
40. Li B., Setoguchi M., Wang X., Andreoli A.M., Leri A., Malhotra A., Kajstura J., and Anversa P. 1999. Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart. Circ. Res. 84: 1007.
41. Li Q., Li B., Wang X., Leri A., Jana K.P., Liu Y., Kajstura J., Baserga R., and Anversa P. 1997. Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J. Clin. Invest. 100: 1991.
42. Liu J., Baker J., Perkins A.S., Robertson E.J., and Efstratiadis A. 1993. Mice carrying null mutations of the genes encoding insulin-like growth factor I (IGF-I) and type I IGF receptor (IGF-Ir). Cell 75: 59.
43. Lowe W.L., Jr., Lasky S.R., LeRoith D., and Roberts C.T., Jr. 1988. Distribution and regulation of rat insulin-like growth factor I messenger ribonucleic acids encoding alternative carboxyterminal E- peptides: Evidence for differential processing and regulation in liver. Mol. Endocrinol. 2: 528.
44. McArdle A., Edwards R.H., and Jackson M.J. 1995. How does dystrophin deficiency lead to muscle degeneration? Evidence from the mdx mouse. Neuromuscul. Disord. 5: 445.
45. McKoy G., Ashley W., Mander J., Yang S.Y., Williams N., Russell B., and Goldspink G. 1999. Expression of insulin growth factor-1 splice variants and structural genes in rabbit skeletal muscle induced by stretch and stimulation. J. Physiol. 516: 583.
46. Musaró A. and Rosenthal N. 1999a. Maturation of the myogenic program is induced by post-mitotic expression of IGF-I. Mol. Cell. Biol. 19: 3115.
47. -. 1999b. Transgenic mouse models of muscle aging. Exp. Gerontol. 34: 147.
48. -. 2002. The role of local insulin-like growth factor-1 isoforms in the pathophysiology of skeletal muscle. Curr. Genomics 3: 149.
49. Musaró A., Cusella De Angelis M.G., Germani A., Ciccarelli C., Molinaro M., and Zani B.M. 1995. Enhanced expression of myogenic regulatory factors in aging skeletal muscle. Exp. Cell Res. 221: 241.
50. Musaró A.; McCullagh K., Paul A., Houghton L., Dobrowolny G., Molinaro M., Barton E.R., Sweeney H.L., and Rosenthal N. 2001. Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle. Nat. Genet. 27: 195.
51. O'Kusky J.R., Ye P., and D'Ercole A.J. 2000. Insulin-like growth factor-I promotes neurogenesis and synaptogenesis in the hippocampal dentate gyrus during postnatal development. J. Neurosci. 20: 8435.
52. Pastoret C. and Sebille A. 1993. Further aspects of muscular dystrophy in mdx mice. Neuromuscul. Disord. 3: 471.
53. Powell-Braxton L., P. Hollingshead P., Warburton C., Dowd M., Pitts-Meek S., Dalton D., Gillett N., and Stewart T.A. 1993. IGF-I is required for normal embryonic growth in mice. Genes Dev. 7: 2609.
54. Reiss K., Cheng W., Ferber A., Kajstura J., Li P., Li B., Olivetti G., Homcy C.J., Baserga R., and Anversa P. 1996. Overexpression of insulin-like growth factor-I in the heart is coupled with myocyte proliferation in transgenic mice. Proc. Natl. Acad. Sci. 93: 8630.
55. Renganathan M. and Delbono O. 1998. Caloric restriction prevents age-related decline in skeletal muscle dihydropyridine receptor and ryanodine receptor expression. FEBS Lett. 434: 346.
56. Renganathan M., Messi M.L., Schwartz R., and Delbono O. 1997. Overexpression of hIGF-1 exclusively in skeletal muscle increases the number of dihydropyridine receptors in adult transgenic mice. FEBS Lett. 417: 13.
57. Rinderknecht E. and Humbel R.E. 1978. The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. J. Biol. Chem. 253: 2769.
58. Rowland L.P. and Shneider N.A. 2001. Amyotrophic lateral sclerosis. N. Engl. J. Med. 344: 1688.
59. Shimatsu A. and Rotwein P. 1987a. Mosaic evolution of the insulin-like growth factors: Organization, sequence, and expression of the rat insulin-like growth factor I gene. J. Biol. Chem. 262: 7894.
60. -. 1987b. Sequence of two rat insulin-like growth factor I mRNAs differing within the 5′ untranslated region. Nucleic Acids Res. 15: 7196.
61. Sicinski P., Geng Y., Ryder-Cook A.S., Barnard E.A., Darlison M.G., and Barnard P.J. 1989. The molecular basis of muscular dystrophy in the mdx mouse: A point mutation. Science 244: 1578.
62. Simmons J.G., Van Wyk J.J., Hoyt E.C., and Lund P.K. 1993. Multiple transcription start sites in the rat insulin-like growth factor-I gene give rise to IGF-I mRNAs that encode different IGF-I precursors and are processed differently in vitro. Growth Factors 9: 205.
63. Sjogren K., Liu J.L., Blad K., Skrtic S., Vidal O., Wallenius V., LeRoith D., Tornell J., Isaksson O.G., Jansson J.O., and Ohlsson C. 1999. Liver-derived IGF-I is the principal source of IGF-I in blood but is not required for postnatal body growth in mice. Proc. Natl. Acad. Sci. 96: 7088.
64. Stedman H.H., Sweeney H.L., Shrager J.B., Maguire H.C., Panettieri R.A., Petrof B., Narusawa M., Leferovich J.M., Sladky J.T., and Kelly A.M. 1991. The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy. Nature 352: 536.
65. Stewart C.E. and Rotwein P. 1996. Growth, differentation, and survival: Multiple physiological functions for insulin-like growth factors. Physiol. Rev. 76: 1005.
66. Tiangco D.A., Papakonstantinou K.C., Mullinax K.A., and Terzis J.K. 2001. IGF-I and end-to-side nerve repair: A dose-response study. J. Reconstr. Microsurg. 17: 247.
67. van Buul-Offers S.C. and Kooijman R. 1998. The role of growth hormone and insulin-like growth factors in the immune system. Cell Mol. Life Sci. 54: 1083.
68. Velasco B., Cacicedo L., Escalada J., Lopez-Fernandez J., and Sanchez-Franco F. 1998. Growth hormone gene expression and secretion in aging rats is age dependent and not age-associated weight increase related. Endocrinology 139: 1314.
69. Vickers M.H., Ikenasio B.A., and Breier B.H. 2001. IGF-I treatment reduces hyperphagia, obesity, and hypertension in metabolic disorders induced by fetal programming. Endocrinology 142: 3964.
70. Yang S., Alnaqeeb M., Simpson H., and Goldspink G. 1996. Cloning and characterization of an IGF-1 isoform expressed in skeletal muscle subjected to stretch. J. Muscle Res. Cell Motil. 17: 487.
71. Ye P., Lee K.H., and D'Ercole A.J. 2000. Insulin-like growth factor-I (IGF-I) protects myelination from undernutritional insult: Studies of transgenic mice overexpressing IGF-I in brain. J. Neurosci. Res. 62: 700.