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Volumn 29, Issue 6, 2007, Pages 701-711

Recent advances in metabonomics

Author keywords

Mass spectrometay; Metabolomics; Metabonomics; System biology

Indexed keywords

BIOLOGICAL MARKER;

EID: 38849175481     PISSN: 1000503X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial
Times cited : (19)

References (103)
  • 1
    • 0032694577 scopus 로고    scopus 로고
    • Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data [J]
    • Nicholson JK, Lindon JC, Holmes E. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data [J]. Xenobiotica, 1999, 29(11):1181-1189.
    • (1999) Xenobiotica , vol.29 , Issue.11 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 2
    • 0033757963 scopus 로고    scopus 로고
    • Metabolite profiling for plant functional genomics [J]
    • Fiehn O, Kopka J, Dormann P, et al. Metabolite profiling for plant functional genomics [J]. Nat Biotechnol, 2000, 18(11):1157-1161.
    • (2000) Nat Biotechnol , vol.18 , Issue.11 , pp. 1157-1161
    • Fiehn, O.1    Kopka, J.2    Dormann, P.3
  • 3
    • 0018137689 scopus 로고
    • Quantitative metabolic profiling based on gas chromatography [J]
    • Gates SC, Sweeley CC. Quantitative metabolic profiling based on gas chromatography [J]. Clin Chem, 1978, 24 (10):1663-1673.
    • (1978) Clin Chem , vol.24 , Issue.10 , pp. 1663-1673
    • Gates, S.C.1    Sweeley, C.C.2
  • 4
    • 0020548934 scopus 로고
    • Urine profile analysis by field desorption mass spectrometry, a technique for detecting metabolites of xenobiotics. Application to 3, 5-dinitro-2-hydroxytoluene [J]
    • van der Greef J, Leegwater DC. Urine profile analysis by field desorption mass spectrometry, a technique for detecting metabolites of xenobiotics. Application to 3, 5-dinitro-2-hydroxytoluene [J]. Biomed Mass Spectrom, 1983, 10 (1):1-4.
    • (1983) Biomed Mass Spectrom , vol.10 , Issue.1 , pp. 1-4
    • van der Greef, J.1    Leegwater, D.C.2
  • 5
    • 0036913503 scopus 로고    scopus 로고
    • Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using H-1-NMR-based metabonomics [J]
    • Brindle JT, Antti H, Holmes E, et al. Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using H-1-NMR-based metabonomics [J]. Nat Med, 2002, 8(12):1439-1444.
    • (2002) Nat Med , vol.8 , Issue.12 , pp. 1439-1444
    • Brindle, J.T.1    Antti, H.2    Holmes, E.3
  • 6
    • 0030750492 scopus 로고    scopus 로고
    • From gene to screen with yeast [J]
    • Oliver SG. From gene to screen with yeast [J]. Curr Opin Genet Dev, 1997, 7(3):405-409.
    • (1997) Curr Opin Genet Dev , vol.7 , Issue.3 , pp. 405-409
    • Oliver, S.G.1
  • 7
    • 33748081440 scopus 로고    scopus 로고
    • A special issue on data standards [J]
    • Field D, Sansone SA. A special issue on data standards [J]. Omics, 2006, 10(2):84-93.
    • (2006) Omics , vol.10 , Issue.2 , pp. 84-93
    • Field, D.1    Sansone, S.A.2
  • 8
    • 33748067327 scopus 로고    scopus 로고
    • Establishing reporting standards for metabolomic and metabonomic studies: A call for participation [J]
    • Fiehn O, Kristal B, Van Ommen B, et al. Establishing reporting standards for metabolomic and metabonomic studies: a call for participation [J]. Omics, 2006, 10(2): 158-163.
    • (2006) Omics , vol.10 , Issue.2 , pp. 158-163
    • Fiehn, O.1    Kristal, B.2    Van Ommen, B.3
  • 9
    • 24944444149 scopus 로고    scopus 로고
    • Summary recommendations for standardization and reporting of metabolic analyses [J]
    • Lindon JC, Nicholson JK, Holmes E, et al. Summary recommendations for standardization and reporting of metabolic analyses [J]. Nat Biotechnol, 2005, 23(7):833-838.
    • (2005) Nat Biotechnol , vol.23 , Issue.7 , pp. 833-838
    • Lindon, J.C.1    Nicholson, J.K.2    Holmes, E.3
  • 11
    • 33745753110 scopus 로고    scopus 로고
    • The role of mass spectrometry in biomarker discovery and measurement [J]
    • Ackermann BL, Hale JE, Duffin KL. The role of mass spectrometry in biomarker discovery and measurement [J]. Curr Drug Metab, 2006, 7(5):525-539.
    • (2006) Curr Drug Metab , vol.7 , Issue.5 , pp. 525-539
    • Ackermann, B.L.1    Hale, J.E.2    Duffin, K.L.3
  • 12
    • 16244402990 scopus 로고    scopus 로고
    • Dunn WB, Ellis DI. Metabolomics: current analytical platforms and methodologies [J]. Truc Trends Anal Chem, 2005, 24(4):285-294.
    • Dunn WB, Ellis DI. Metabolomics: current analytical platforms and methodologies [J]. Truc Trends Anal Chem, 2005, 24(4):285-294.
  • 13
    • 33748603444 scopus 로고    scopus 로고
    • Metabolomics: Current technologies and future trends [J]
    • Hollywood K, Brison DR, Goodacre R. Metabolomics: current technologies and future trends [J]. Proteomics, 2006, 6(17):4716-4723.
    • (2006) Proteomics , vol.6 , Issue.17 , pp. 4716-4723
    • Hollywood, K.1    Brison, D.R.2    Goodacre, R.3
  • 14
    • 18844406001 scopus 로고    scopus 로고
    • Measuring the metabolome: Current analytical technologies [J]
    • Dunn WB, Bailey NJC, Johnson HE. Measuring the metabolome: current analytical technologies [J]. Analyst, 2005, 130(5):606-625.
    • (2005) Analyst , vol.130 , Issue.5 , pp. 606-625
    • Dunn, W.B.1    Bailey, N.J.C.2    Johnson, H.E.3
  • 15
    • 8844261879 scopus 로고    scopus 로고
    • Diagnosis of liver cancer using HPLC-based metabonomics avoiding false-positive result from hepatitis and hepatocirrhosis diseases [J]
    • Yang J, Xu GW, Zheng YF, et al. Diagnosis of liver cancer using HPLC-based metabonomics avoiding false-positive result from hepatitis and hepatocirrhosis diseases [J]. J Chromatogr B, 2004, 813(1-2):59-65.
    • (2004) J Chromatogr B , vol.813 , Issue.1-2 , pp. 59-65
    • Yang, J.1    Xu, G.W.2    Zheng, Y.F.3
  • 16
    • 34547712615 scopus 로고    scopus 로고
    • Metabonomics: A new frontier of nuclear magnetic resonance (NMR) [J]
    • Govil G. Metabonomics: a new frontier of nuclear magnetic resonance (NMR) [J]. Natl Acad Sci Lett India, 2004, 27(9-10):289-299.
    • (2004) Natl Acad Sci Lett India , vol.27 , Issue.9-10 , pp. 289-299
    • Govil, G.1
  • 18
    • 0038439465 scopus 로고    scopus 로고
    • On-line preconcentration strategies for trace analysis of metabolites by capillary electrophoresis [J]
    • Britz-McKibbin P, Terabe S. On-line preconcentration strategies for trace analysis of metabolites by capillary electrophoresis [J]. J Chromatogr A, 2003, 1000(1-2):917-934.
    • (2003) J Chromatogr A , vol.1000 , Issue.1-2 , pp. 917-934
    • Britz-McKibbin, P.1    Terabe, S.2
  • 19
    • 0037185964 scopus 로고    scopus 로고
    • FT-IR spectroscopic investigations of single cells on the subcellular level [J]
    • Lasch P, Boese M, Pacifico A, et al. FT-IR spectroscopic investigations of single cells on the subcellular level [J]. Vib Spectrosc, 2002, 28(1):147-157.
    • (2002) Vib Spectrosc , vol.28 , Issue.1 , pp. 147-157
    • Lasch, P.1    Boese, M.2    Pacifico, A.3
  • 20
    • 0036683501 scopus 로고    scopus 로고
    • Identification of scrapie infection from blood serum by Fourier transform infrared spectroscopy [J]
    • Schmitt J, Beekes M, Brauer A, et al. Identification of scrapie infection from blood serum by Fourier transform infrared spectroscopy [J]. Anal Chem, 2002, 74(15): 3865-3868.
    • (2002) Anal Chem , vol.74 , Issue.15 , pp. 3865-3868
    • Schmitt, J.1    Beekes, M.2    Brauer, A.3
  • 21
    • 10044257788 scopus 로고    scopus 로고
    • Metabolomic applications of electrochemistry/mass spectrometry [J]
    • Gamache PH, Meyer DF, Granger MC, et al. Metabolomic applications of electrochemistry/mass spectrometry [J]. J Am Soc Mass Spectrom, 2004, 15(12):1717-1726.
    • (2004) J Am Soc Mass Spectrom , vol.15 , Issue.12 , pp. 1717-1726
    • Gamache, P.H.1    Meyer, D.F.2    Granger, M.C.3
  • 22
    • 0035866674 scopus 로고    scopus 로고
    • Application of directly coupled HPLC MMR to separation and characterization of lipoproteins from human serum [J]
    • Daykin CA, Corcoran O, Hansen SH, et al. Application of directly coupled HPLC MMR to separation and characterization of lipoproteins from human serum [J]. Anal Chem, 2001, 73(6):1084-1090.
    • (2001) Anal Chem , vol.73 , Issue.6 , pp. 1084-1090
    • Daykin, C.A.1    Corcoran, O.2    Hansen, S.H.3
  • 23
    • 13244264923 scopus 로고    scopus 로고
    • Metabolite finger-printing and profiling in plants using NMR [J]
    • Krishnan P, Kruger NJ, Ratcliffe RG. Metabolite finger-printing and profiling in plants using NMR [J]. J Exp Bot, 2005, 56(410):255-265.
    • (2005) J Exp Bot , vol.56 , Issue.410 , pp. 255-265
    • Krishnan, P.1    Kruger, N.J.2    Ratcliffe, R.G.3
  • 24
    • 0033743932 scopus 로고    scopus 로고
    • NMR spectroscopy based metabonomic studies on the comparative biochemistry of the kidney and urine of the bank vole (Clethrionomys glareolus), wood mouse (Apodemus sylvaticus), white toothed shrew (Crocidura suaveolens) and the laboratory rat [J]
    • Griffin JL, Walker LA, Garrod S, et al. NMR spectroscopy based metabonomic studies on the comparative biochemistry of the kidney and urine of the bank vole (Clethrionomys glareolus), wood mouse (Apodemus sylvaticus), white toothed shrew (Crocidura suaveolens) and the laboratory rat [J]. Comp Biochem Physiol B Biochem Mol Biol, 2000, 127(3):357-367.
    • (2000) Comp Biochem Physiol B Biochem Mol Biol , vol.127 , Issue.3 , pp. 357-367
    • Griffin, J.L.1    Walker, L.A.2    Garrod, S.3
  • 25
    • 4644262109 scopus 로고    scopus 로고
    • Metabonomics: Its potential as a tool in toxicology for safety assessment and data integration [J]
    • Griffin JL, Bollard ME. Metabonomics: its potential as a tool in toxicology for safety assessment and data integration [J]. Curr Drug Metab, 2004, 5(5):389-398.
    • (2004) Curr Drug Metab , vol.5 , Issue.5 , pp. 389-398
    • Griffin, J.L.1    Bollard, M.E.2
  • 26
    • 0142138236 scopus 로고    scopus 로고
    • Metabonomics: NMR spectroscopy and pattern recognition analysis of body fluids and tissues for characterisation of xenobiotic toxicity and disease diagnosis [J]
    • Griffin JL. Metabonomics: NMR spectroscopy and pattern recognition analysis of body fluids and tissues for characterisation of xenobiotic toxicity and disease diagnosis [J]. Curr Opin Chem Biol, 2003, 7(5):648-654.
    • (2003) Curr Opin Chem Biol , vol.7 , Issue.5 , pp. 648-654
    • Griffin, J.L.1
  • 27
    • 12244269071 scopus 로고    scopus 로고
    • High-resolution NMR for metabomics [J]
    • Pelczer I. High-resolution NMR for metabomics [J]. Curr Opin Drug Discov Dev, 2005, 8(1):127-133.
    • (2005) Curr Opin Drug Discov Dev , vol.8 , Issue.1 , pp. 127-133
    • Pelczer, I.1
  • 28
    • 0034634448 scopus 로고    scopus 로고
    • An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: Application to the C57BL10J and Alpk: ApfCD mouse [J]
    • Gavaghan CL, Holmes E, Lenz E, et al. An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk: ApfCD mouse [J]. FEBS Lett, 2000, 484(3):169-174.
    • (2000) FEBS Lett , vol.484 , Issue.3 , pp. 169-174
    • Gavaghan, C.L.1    Holmes, E.2    Lenz, E.3
  • 29
    • 0035107971 scopus 로고    scopus 로고
    • Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks [J]
    • Holmes E, Nicholson JK, Tranter G. Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks [J]. Chem Res Toxicol, 2001, 14(2):182-191.
    • (2001) Chem Res Toxicol , vol.14 , Issue.2 , pp. 182-191
    • Holmes, E.1    Nicholson, J.K.2    Tranter, G.3
  • 30
    • 20044389660 scopus 로고    scopus 로고
    • A functional analysis of mouse models of cardiac disease through metabolic profiling [J]
    • Jones G, Sang E, Goddard C, et al. A functional analysis of mouse models of cardiac disease through metabolic profiling [J]. J Biol Chem, 2005, 280(9):7530-7539.
    • (2005) J Biol Chem , vol.280 , Issue.9 , pp. 7530-7539
    • Jones, G.1    Sang, E.2    Goddard, C.3
  • 31
    • 33847378014 scopus 로고    scopus 로고
    • Rapid and noninvasive metabonomic characterization of inflammatory bowel disease [J]
    • Marchesi JR, Holmes E, Khan F, et al. Rapid and noninvasive metabonomic characterization of inflammatory bowel disease [J]. J Proteome Res, 2007, 6(2):546-551.
    • (2007) J Proteome Res , vol.6 , Issue.2 , pp. 546-551
    • Marchesi, J.R.1    Holmes, E.2    Khan, F.3
  • 32
    • 33644896212 scopus 로고    scopus 로고
    • The role of mass spectrometry in plant systems biology [J]
    • Glinski M, Weckwerth W. The role of mass spectrometry in plant systems biology [J]. Mass Spectrom Rev, 2006, 25(2):173-214.
    • (2006) Mass Spectrom Rev , vol.25 , Issue.2 , pp. 173-214
    • Glinski, M.1    Weckwerth, W.2
  • 33
    • 33845314350 scopus 로고    scopus 로고
    • Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors [J]
    • Denkert C, Budczies J, Kind T, et al. Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors [J]. Cancer Res, 2006, 66(22):10795-10804.
    • (2006) Cancer Res , vol.66 , Issue.22 , pp. 10795-10804
    • Denkert, C.1    Budczies, J.2    Kind, T.3
  • 34
    • 33847002010 scopus 로고    scopus 로고
    • Systematic identification of conserved metabolites in GC/MS data for metabolomics and biomarker discovery [J]
    • Styczynski MP, Moxley JF, Tong LV, et al. Systematic identification of conserved metabolites in GC/MS data for metabolomics and biomarker discovery [J]. Anal Chem, 2007, 79(3):966-973.
    • (2007) Anal Chem , vol.79 , Issue.3 , pp. 966-973
    • Styczynski, M.P.1    Moxley, J.F.2    Tong, L.V.3
  • 35
    • 33847358695 scopus 로고    scopus 로고
    • Analytical strategies in metabonomics [J]
    • Lenz EM, Wilson ID. Analytical strategies in metabonomics [J]. J Proteome Res, 2007, 6(2):443-458.
    • (2007) J Proteome Res , vol.6 , Issue.2 , pp. 443-458
    • Lenz, E.M.1    Wilson, I.D.2
  • 36
    • 12944320855 scopus 로고    scopus 로고
    • HPLC-MS-based methods for the study of metabonomics [J]
    • Wilson ID, Plumb R, Granger J, et al. HPLC-MS-based methods for the study of metabonomics [J]. J Chromatogr B, 2005, 817(1):67-76.
    • (2005) J Chromatogr B , vol.817 , Issue.1 , pp. 67-76
    • Wilson, I.D.1    Plumb, R.2    Granger, J.3
  • 37
    • 33644835571 scopus 로고    scopus 로고
    • High performance liquid chromatography-mass spectrometry for metabonomics: Potential biomarkers for acute deterioration of liver function in chronic hepatitis B [J]
    • Yang J, Zhao XJ, Liu XL, et al. High performance liquid chromatography-mass spectrometry for metabonomics: potential biomarkers for acute deterioration of liver function in chronic hepatitis B [J]. J Proteome Res, 2006, 5(3): 554-561.
    • (2006) J Proteome Res , vol.5 , Issue.3 , pp. 554-561
    • Yang, J.1    Zhao, X.J.2    Liu, X.L.3
  • 38
    • 34247115128 scopus 로고    scopus 로고
    • Tools in metabonomics: An integrated validation approach for LC-MS metabolic profiling of mercapturic acids in human urine [J]
    • Wagner S, Scholz K, Sieber M, et al. Tools in metabonomics: an integrated validation approach for LC-MS metabolic profiling of mercapturic acids in human urine [J]. Anal Chem, 2007, 79(7):2918-2926.
    • (2007) Anal Chem , vol.79 , Issue.7 , pp. 2918-2926
    • Wagner, S.1    Scholz, K.2    Sieber, M.3
  • 39
    • 33746606019 scopus 로고    scopus 로고
    • Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry [J]
    • Bajad SU, Lu WY, Kimball EH, et al. Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry [J]. J Chromatogr A, 2006, 1125(1):76-88.
    • (2006) J Chromatogr A , vol.1125 , Issue.1 , pp. 76-88
    • Bajad, S.U.1    Lu, W.Y.2    Kimball, E.H.3
  • 40
    • 33748316468 scopus 로고    scopus 로고
    • Metabonomics study of intestinal fistulas based on ultraperformance liquid chromatography coupled with Q-TOF mass spectrometry (UPLC/Q-TOF MS) [J]
    • Yin PY, Zhao XJ, Li QR, et al. Metabonomics study of intestinal fistulas based on ultraperformance liquid chromatography coupled with Q-TOF mass spectrometry (UPLC/Q-TOF MS) [J]. J Proteome Res, 2006, 5(9):2135-2143.
    • (2006) J Proteome Res , vol.5 , Issue.9 , pp. 2135-2143
    • Yin, P.Y.1    Zhao, X.J.2    Li, Q.R.3
  • 41
    • 33749512402 scopus 로고    scopus 로고
    • The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry [J]
    • Plumb RS, Johnson KA, Rainville P, et al. The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry [J]. Rapid Commun Mass Spectrom, 2006, 20(19):2800-2806.
    • (2006) Rapid Commun Mass Spectrom , vol.20 , Issue.19 , pp. 2800-2806
    • Plumb, R.S.1    Johnson, K.A.2    Rainville, P.3
  • 42
    • 17644385894 scopus 로고    scopus 로고
    • Metabonomic studies comparing capillary and conventional HPLC-oa-TOF MS for the analysis of urine from Zucker obese rats [J]
    • Granger J, Plumb R, Castro-Perez J, et al. Metabonomic studies comparing capillary and conventional HPLC-oa-TOF MS for the analysis of urine from Zucker obese rats [J]. Chromatographia, 2005, 61(7-8):375-380.
    • (2005) Chromatographia , vol.61 , Issue.7-8 , pp. 375-380
    • Granger, J.1    Plumb, R.2    Castro-Perez, J.3
  • 43
    • 33750055741 scopus 로고    scopus 로고
    • Clarification of pathway-specific inhibition by Fourier transform ion cyclotron resonance/ mass spectrometry-based metabolic phenotyping studies [J]
    • Oikawa A, Nakamura Y, Ogura T, et al. Clarification of pathway-specific inhibition by Fourier transform ion cyclotron resonance/ mass spectrometry-based metabolic phenotyping studies [J]. Plant Physiol, 2006, 142(2): 398-413.
    • (2006) Plant Physiol , vol.142 , Issue.2 , pp. 398-413
    • Oikawa, A.1    Nakamura, Y.2    Ogura, T.3
  • 44
    • 38849206850 scopus 로고    scopus 로고
    • Chinese source.
    • Chinese source.
  • 45
    • 38849137189 scopus 로고    scopus 로고
    • Chinese source.
    • Chinese source.
  • 46
    • 38849209119 scopus 로고    scopus 로고
    • Chinese source.
    • Chinese source.
  • 47
    • 0036798490 scopus 로고    scopus 로고
    • Application of orthogonal signal correction to minimise the effects of physical and biological variation in high resolution H-1 NMR spectra of biofluids [J]
    • Beckwith-Hall BM, Brindle JT, Barton RH, et al. Application of orthogonal signal correction to minimise the effects of physical and biological variation in high resolution H-1 NMR spectra of biofluids [J]. Analyst, 2002, 127(10): 1283-1288.
    • (2002) Analyst , vol.127 , Issue.10 , pp. 1283-1288
    • Beckwith-Hall, B.M.1    Brindle, J.T.2    Barton, R.H.3
  • 48
    • 38849121311 scopus 로고    scopus 로고
    • Evaluation of filtering effects of orthogonal signal correction on metalmonomic analysis of healthy human serum H-1 NMR spectra [J]
    • Mao HL, Xu M, Wang B, et al. Evaluation of filtering effects of orthogonal signal correction on metalmonomic analysis of healthy human serum H-1 NMR spectra [J]. Acta Chim Sin, 2007, 65(2):152-158.
    • (2007) Acta Chim Sin , vol.65 , Issue.2 , pp. 152-158
    • Mao, H.L.1    Xu, M.2    Wang, B.3
  • 49
    • 0032076034 scopus 로고    scopus 로고
    • Aligning of single and multiple wavelength chromatographic profiles for chemometric data analysis using correlation optimised warping [J]
    • Nielsen NPV, Carstensen JM, Smedsgaard J. Aligning of single and multiple wavelength chromatographic profiles for chemometric data analysis using correlation optimised warping [J]. J Chromatogr A, 1998, 805(1-2):17-35.
    • (1998) J Chromatogr A , vol.805 , Issue.1-2 , pp. 17-35
    • Nielsen, N.P.V.1    Carstensen, J.M.2    Smedsgaard, J.3
  • 50
    • 1542408614 scopus 로고    scopus 로고
    • A strategy for identifying differences in large series of metabolomic samples analyzed by GC/MS [J]
    • Jonsson P, Gullberg J, Nordstrom A, et al. A strategy for identifying differences in large series of metabolomic samples analyzed by GC/MS [J]. Anal Chem, 2004, 76 (6):1738-1745.
    • (2004) Anal Chem , vol.76 , Issue.6 , pp. 1738-1745
    • Jonsson, P.1    Gullberg, J.2    Nordstrom, A.3
  • 51
    • 22044449913 scopus 로고    scopus 로고
    • Strategy for metabonomics research based on high-performance liquid chromatography and liquid chromatography coupled with tandem mass spectrometry [J]
    • Yang J, Xu GW, Zheng WF, et al. Strategy for metabonomics research based on high-performance liquid chromatography and liquid chromatography coupled with tandem mass spectrometry [J]. J Chromatogr A, 2005, 1084(1-2):214-221.
    • (2005) J Chromatogr A , vol.1084 , Issue.1-2 , pp. 214-221
    • Yang, J.1    Xu, G.W.2    Zheng, W.F.3
  • 52
    • 33746819836 scopus 로고    scopus 로고
    • Metabolomic approaches to phenotype characterization and applications to complex diseases [J]
    • Oresic M, Vidal-Puig A, Hanninen V. Metabolomic approaches to phenotype characterization and applications to complex diseases [J]. Expert Rev Mol Diagn, 2006, 6 (4):575-585.
    • (2006) Expert Rev Mol Diagn , vol.6 , Issue.4 , pp. 575-585
    • Oresic, M.1    Vidal-Puig, A.2    Hanninen, V.3
  • 53
    • 34247397544 scopus 로고    scopus 로고
    • Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in type 2 diabetes mellitus patients and healthy volunteers [J]
    • van Doorn M, Vogels J, Tas A, et al. Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in type 2 diabetes mellitus patients and healthy volunteers [J]. Br J Clin Pharmacol, 2007, 63(5):562-574.
    • (2007) Br J Clin Pharmacol , vol.63 , Issue.5 , pp. 562-574
    • van Doorn, M.1    Vogels, J.2    Tas, A.3
  • 54
    • 33947205645 scopus 로고    scopus 로고
    • Metabolomics by proton nuclear magnetic resonance spectroscopy of the response to chloro-ethylnitrosourea reveals drug efficacy and tumor adaptive metabolic pathways [J]
    • Morvan D, Demidem A. Metabolomics by proton nuclear magnetic resonance spectroscopy of the response to chloro-ethylnitrosourea reveals drug efficacy and tumor adaptive metabolic pathways [J]. Cancer Res, 2007, 67(5): 2150-2159.
    • (2007) Cancer Res , vol.67 , Issue.5 , pp. 2150-2159
    • Morvan, D.1    Demidem, A.2
  • 55
    • 33745700438 scopus 로고    scopus 로고
    • Targeted profiling: Quantitative analysis of H-1 NMR metabolomics data [J]
    • Weljie AM, Newton J, Mercier P, et al. Targeted profiling: quantitative analysis of H-1 NMR metabolomics data [J]. Anal Chem, 2006, 78(13):4430-4442.
    • (2006) Anal Chem , vol.78 , Issue.13 , pp. 4430-4442
    • Weljie, A.M.1    Newton, J.2    Mercier, P.3
  • 56
    • 0036917875 scopus 로고    scopus 로고
    • Chemometric contributions to the evolution of metabonomics: Mathematical solutions to characterising and interpreting complex biological NMR spectra [J]
    • Holmes E, Antti H. Chemometric contributions to the evolution of metabonomics: mathematical solutions to characterising and interpreting complex biological NMR spectra [J]. Analyst, 2002, 127(12):1549-1557.
    • (2002) Analyst , vol.127 , Issue.12 , pp. 1549-1557
    • Holmes, E.1    Antti, H.2
  • 57
    • 2442651602 scopus 로고    scopus 로고
    • Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles [J]
    • Keun HC, Ebbels TMD, Bollard ME, et al. Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles [J]. Chem Res Toxicol, 2004, 17(5):579-587.
    • (2004) Chem Res Toxicol , vol.17 , Issue.5 , pp. 579-587
    • Keun, H.C.1    Ebbels, T.M.D.2    Bollard, M.E.3
  • 58
    • 33745714500 scopus 로고    scopus 로고
    • Metabolic profiling of glucuronides in human urine by LC-MS/MS and partial least-squares discriminant analysis for classification and prediction of gender [J]
    • Lutz U, Lutz RW, Lutz WK. Metabolic profiling of glucuronides in human urine by LC-MS/MS and partial least-squares discriminant analysis for classification and prediction of gender [J]. Anal Chem, 2006, 78(13):4564-4571.
    • (2006) Anal Chem , vol.78 , Issue.13 , pp. 4564-4571
    • Lutz, U.1    Lutz, R.W.2    Lutz, W.K.3
  • 59
    • 0034130232 scopus 로고    scopus 로고
    • Chemometric models for toxicity classification based on NMR spectra of biofluids [J]
    • Holmes E, Nicholls AW, Lindon JC, et al. Chemometric models for toxicity classification based on NMR spectra of biofluids [J]. Chem Res Toxicol, 2000, 13(6):471-478.
    • (2000) Chem Res Toxicol , vol.13 , Issue.6 , pp. 471-478
    • Holmes, E.1    Nicholls, A.W.2    Lindon, J.C.3
  • 60
    • 21644479604 scopus 로고    scopus 로고
    • Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis [J]
    • Wang C, Kong HW, Guan YF, et al. Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis [J]. Anal Chem, 2005, 77(13):4108-4116.
    • (2005) Anal Chem , vol.77 , Issue.13 , pp. 4108-4116
    • Wang, C.1    Kong, H.W.2    Guan, Y.F.3
  • 61
    • 33745700684 scopus 로고    scopus 로고
    • Impact of analytical bias in metabonomic studies of human blood serum and plasma [J]
    • Teahan O, Gamble S, Holmes E, et al. Impact of analytical bias in metabonomic studies of human blood serum and plasma [J]. Anal Chem, 2006, 78(13):4307-4318.
    • (2006) Anal Chem , vol.78 , Issue.13 , pp. 4307-4318
    • Teahan, O.1    Gamble, S.2    Holmes, E.3
  • 62
    • 33645663178 scopus 로고    scopus 로고
    • Scaling and normalization effects in NMR spectroscopic metabonomic data sets [J]
    • Craig A, Cloareo O, Holmes E, et al. Scaling and normalization effects in NMR spectroscopic metabonomic data sets [J]. Anal Chem, 2006, 78(7):2262-2267.
    • (2006) Anal Chem , vol.78 , Issue.7 , pp. 2262-2267
    • Craig, A.1    Cloareo, O.2    Holmes, E.3
  • 63
    • 33747019547 scopus 로고    scopus 로고
    • Centering, scaling, and transformations: Improving the biological information content of metabolomics data [J]
    • van den Berg RA, Hoefsloot HCJ, Westerhuis JA, et al. Centering, scaling, and transformations: improving the biological information content of metabolomics data [J]. BMC Genomics, 2006, 7:15.
    • (2006) BMC Genomics , vol.7 , pp. 15
    • van den Berg, R.A.1    Hoefsloot, H.C.J.2    Westerhuis, J.A.3
  • 64
    • 33847388440 scopus 로고    scopus 로고
    • Robertson DG, Reily MD, Baker JD. Metabonomics in pharmaceutical discovery and development [J]. J Proteome Res, 2007, 6(2):526-539.
    • Robertson DG, Reily MD, Baker JD. Metabonomics in pharmaceutical discovery and development [J]. J Proteome Res, 2007, 6(2):526-539.
  • 65
    • 28444480986 scopus 로고    scopus 로고
    • Metabonomic modeling of drug toxicity [J]
    • Keun HC. Metabonomic modeling of drug toxicity [J]. Pharmacol Ther, 2006, 109(1-2):92-106.
    • (2006) Pharmacol Ther , vol.109 , Issue.1-2 , pp. 92-106
    • Keun, H.C.1
  • 66
    • 33751356224 scopus 로고    scopus 로고
    • Systems biology, metabolic modelling and metabolomics in drug discovery and development [J]
    • Kell DB. Systems biology, metabolic modelling and metabolomics in drug discovery and development [J]. Drug Discov Today, 2006, 11(23-24):1085-1092.
    • (2006) Drug Discov Today , vol.11 , Issue.23-24 , pp. 1085-1092
    • Kell, D.B.1
  • 67
    • 1542268299 scopus 로고    scopus 로고
    • Metabonomics and its role in drug development and disease diagnosis [J]
    • Lindon JC, Holmes E, Nicholson JK. Metabonomics and its role in drug development and disease diagnosis [J]. Expert Rev Mol Diagn, 2004, 4(2):189-199.
    • (2004) Expert Rev Mol Diagn , vol.4 , Issue.2 , pp. 189-199
    • Lindon, J.C.1    Holmes, E.2    Nicholson, J.K.3
  • 68
    • 33745823913 scopus 로고    scopus 로고
    • Systems toxicology: Integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat [J]
    • Craig A, Sidaway J, Holmes E, et al. Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat [J]. J Proteome Res, 2006, 5(7):1586-1601.
    • (2006) J Proteome Res , vol.5 , Issue.7 , pp. 1586-1601
    • Craig, A.1    Sidaway, J.2    Holmes, E.3
  • 69
    • 0036639485 scopus 로고    scopus 로고
    • NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate [J]
    • Waters NJ, Holmes E, Waterfield CJ, et al. NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate [J]. Biochem Pharmacol, 2002, 64(1):67-77.
    • (2002) Biochem Pharmacol , vol.64 , Issue.1 , pp. 67-77
    • Waters, N.J.1    Holmes, E.2    Waterfield, C.J.3
  • 70
    • 26944489574 scopus 로고    scopus 로고
    • The consortium for metabonomic toxicology (COMET): Aims, activities and achievements [J]
    • Lindon JC, Keun HC, Ebbels TMD, et al. The consortium for metabonomic toxicology (COMET): aims, activities and achievements [J]. Pharmacogenomics, 2005, 6(7): 691-699.
    • (2005) Pharmacogenomics , vol.6 , Issue.7 , pp. 691-699
    • Lindon, J.C.1    Keun, H.C.2    Ebbels, T.M.D.3
  • 71
    • 0037444362 scopus 로고    scopus 로고
    • Contemporary issues in toxicology-the role of metabonomics in toxicology and its evaluation by the COMET project [J]
    • Lindon JC, Nicholson JK, Holmes E, et al. Contemporary issues in toxicology-the role of metabonomics in toxicology and its evaluation by the COMET project [J]. Toxicol Appl. Pharmacol, 2003, 187(3):137-146.
    • (2003) Toxicol Appl. Pharmacol , vol.187 , Issue.3 , pp. 137-146
    • Lindon, J.C.1    Nicholson, J.K.2    Holmes, E.3
  • 72
    • 33846242976 scopus 로고    scopus 로고
    • Are 4-hydroxy-2 (E) -nonenal derived mercapturic acids and H-1 NMR metabonomics potential biomarkers of chemically induced oxidative stress in the kidney [J]?
    • Mally A, Amberg A, Hard GC, et al. Are 4-hydroxy-2 (E) -nonenal derived mercapturic acids and H-1 NMR metabonomics potential biomarkers of chemically induced oxidative stress in the kidney [J]? Toxicology, 2007, 230 (2-3):244-255.
    • (2007) Toxicology , vol.230 , Issue.2-3 , pp. 244-255
    • Mally, A.1    Amberg, A.2    Hard, G.C.3
  • 74
    • 33746065648 scopus 로고    scopus 로고
    • Understanding mouse models of disease through metabolomics [J]
    • Griffin JL. Understanding mouse models of disease through metabolomics [J]. Curr Opin Chem Biol, 2006, 10(4): 309-315.
    • (2006) Curr Opin Chem Biol , vol.10 , Issue.4 , pp. 309-315
    • Griffin, J.L.1
  • 75
    • 33750453370 scopus 로고    scopus 로고
    • Monitoring the health to disease continuum with global metabolic profiling and systems biology [J]
    • Schnackenberg LK, Beger RD. Monitoring the health to disease continuum with global metabolic profiling and systems biology [J]. Pharmacogenomics, 2006, 7(7):1077-1086.
    • (2006) Pharmacogenomics , vol.7 , Issue.7 , pp. 1077-1086
    • Schnackenberg, L.K.1    Beger, R.D.2
  • 76
    • 33846064843 scopus 로고    scopus 로고
    • Principal component analysis of urine metabolites detected by NMR and DESI-MS in patients with inborn errors of metabolism [J]
    • Pan ZZ, Gu HW, Talaty N, et al. Principal component analysis of urine metabolites detected by NMR and DESI-MS in patients with inborn errors of metabolism [J]. Anal Bioanal Chem, 2007, 387(2):539-549.
    • (2007) Anal Bioanal Chem , vol.387 , Issue.2 , pp. 539-549
    • Pan, Z.Z.1    Gu, H.W.2    Talaty, N.3
  • 77
    • 27844510139 scopus 로고    scopus 로고
    • Gas chromatographic-mass spectrometric urinary metabolome analysis to study mutations of inborn errors of metabolism [J]
    • Kuhara T. Gas chromatographic-mass spectrometric urinary metabolome analysis to study mutations of inborn errors of metabolism [J]. Mass Spectrom Rev, 2005, 24(6):814-827.
    • (2005) Mass Spectrom Rev , vol.24 , Issue.6 , pp. 814-827
    • Kuhara, T.1
  • 78
    • 33749427046 scopus 로고    scopus 로고
    • The gut microbiota and lipid metabolism: Implications for human health and coronary heart disease [J]
    • Fava F, Lovegrove JA, Gitau R, et al. The gut microbiota and lipid metabolism: implications for human health and coronary heart disease [J]. Curr Med Chem, 2006, 13 (25):3005-3021.
    • (2006) Curr Med Chem , vol.13 , Issue.25 , pp. 3005-3021
    • Fava, F.1    Lovegrove, J.A.2    Gitau, R.3
  • 79
    • 3042788092 scopus 로고    scopus 로고
    • The use of urine proteomic and metabonomic patterns for the diagnosis of interstitial cystitis and bacterial cystitis [J]
    • Van QN, Klose JR, Lucas DA, et al. The use of urine proteomic and metabonomic patterns for the diagnosis of interstitial cystitis and bacterial cystitis [J]. Dis Markers, 2003, 19(4-5):169-183.
    • (2003) Dis Markers , vol.19 , Issue.4-5 , pp. 169-183
    • Van, Q.N.1    Klose, J.R.2    Lucas, D.A.3
  • 80
    • 0037208170 scopus 로고    scopus 로고
    • Application of chemometrics to H-1 NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension [J]
    • Brindle JT, Nicholson JK, Schofield PM, et al. Application of chemometrics to H-1 NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension [J]. Analyst, 2003, 128(1): 32-36.
    • (2003) Analyst , vol.128 , Issue.1 , pp. 32-36
    • Brindle, J.T.1    Nicholson, J.K.2    Schofield, P.M.3
  • 81
    • 24644508329 scopus 로고    scopus 로고
    • Metabolic investigation in psychiatric disorders [J]
    • Yao JK, Reddy RD. Metabolic investigation in psychiatric disorders [J]. Mol Neurobiol, 2005, 31(1-3):193-203.
    • (2005) Mol Neurobiol , vol.31 , Issue.1-3 , pp. 193-203
    • Yao, J.K.1    Reddy, R.D.2
  • 82
    • 33845656562 scopus 로고    scopus 로고
    • Effect of PA-MSHA vaccine on plasma phospholipids metabolic profiling and the ratio of Th2/Th1 cells within immune organ of mouse IgA nephropathy [J]
    • Jia LW, Wang C, Kong HW, et al. Effect of PA-MSHA vaccine on plasma phospholipids metabolic profiling and the ratio of Th2/Th1 cells within immune organ of mouse IgA nephropathy [J]. J Pharm Biomed Anal, 2007, 43 (2):646-654.
    • (2007) J Pharm Biomed Anal , vol.43 , Issue.2 , pp. 646-654
    • Jia, L.W.1    Wang, C.2    Kong, H.W.3
  • 83
    • 33751277894 scopus 로고    scopus 로고
    • Urinary profiling investigation of metabolites with cis-diol structure from cancer patients based on UPLC-MS and HPLC-MS as well as multivariate statistical analysis [J]
    • Zhao XJ, Wang WZ, Wang JS, et al. Urinary profiling investigation of metabolites with cis-diol structure from cancer patients based on UPLC-MS and HPLC-MS as well as multivariate statistical analysis [J]. J Sep Sci, 2006, 29 (16):2444-2451.
    • (2006) J Sep Sci , vol.29 , Issue.16 , pp. 2444-2451
    • Zhao, X.J.1    Wang, W.Z.2    Wang, J.S.3
  • 84
    • 8844226701 scopus 로고    scopus 로고
    • Discrimination of type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles [J]
    • Yang J, Xu GW, Hong QF, et al. Discrimination of type 2 diabetic patients from healthy controls by using metabonomics method based on their serum fatty acid profiles [J]. J Chromatogr B, 2004, 813(1-2):53-58.
    • (2004) J Chromatogr B , vol.813 , Issue.1-2 , pp. 53-58
    • Yang, J.1    Xu, G.W.2    Hong, Q.F.3
  • 85
    • 33746885119 scopus 로고    scopus 로고
    • Plasma phospholipid metabolic profiling and biomarkers of mouse IgA nephropathy [J]
    • Jia LW, Wang C, Kong HW, et al. Plasma phospholipid metabolic profiling and biomarkers of mouse IgA nephropathy [J]. Metabolomics, 2006, 2(2):95-104.
    • (2006) Metabolomics , vol.2 , Issue.2 , pp. 95-104
    • Jia, L.W.1    Wang, C.2    Kong, H.W.3
  • 86
    • 34247216724 scopus 로고    scopus 로고
    • A GC-based metabonomics investigation of type 2 diabetes by organic acids metabolic profile [J]
    • Yuan KL, Kong HW, Guan YF, et al. A GC-based metabonomics investigation of type 2 diabetes by organic acids metabolic profile [J]. J Chromatogr B, 2007, 850(1-2): 236-240.
    • (2007) J Chromatogr B , vol.850 , Issue.1-2 , pp. 236-240
    • Yuan, K.L.1    Kong, H.W.2    Guan, Y.F.3
  • 87
    • 22844447210 scopus 로고    scopus 로고
    • Determination of urinary nucleosides by direct injection and coupled-column high-performance liquid chromatography [J]
    • Zheng YF, Xu GW, Yang J, et al. Determination of urinary nucleosides by direct injection and coupled-column high-performance liquid chromatography [J]. J Chromatogr B, 2005, 819(1):85-90.
    • (2005) J Chromatogr B , vol.819 , Issue.1 , pp. 85-90
    • Zheng, Y.F.1    Xu, G.W.2    Yang, J.3
  • 88
    • 10644236443 scopus 로고    scopus 로고
    • Clinical significance and prognostic value of urinary nucleosides in breast cancer patients [J]
    • Zheng YF, Kong HW, Xiong JH, et al. Clinical significance and prognostic value of urinary nucleosides in breast cancer patients [J]. Clin Biochem, 2005, 38(1):24-30.
    • (2005) Clin Biochem , vol.38 , Issue.1 , pp. 24-30
    • Zheng, Y.F.1    Kong, H.W.2    Xiong, J.H.3
  • 89
    • 33845612720 scopus 로고    scopus 로고
    • Perspective-applications of metabolomics in agriculture [J]
    • Dixon RA, Gang DR, Charlton AJ, et al. Perspective-applications of metabolomics in agriculture [J]. J Agric Food Chem, 2006, 54(24):8984-8994.
    • (2006) J Agric Food Chem , vol.54 , Issue.24 , pp. 8984-8994
    • Dixon, R.A.1    Gang, D.R.2    Charlton, A.J.3
  • 90
    • 4444309760 scopus 로고    scopus 로고
    • Potential of metabolomics as a functional genomics tool [J]
    • Bino RJ, Hall RD, Fiehn O, et al. Potential of metabolomics as a functional genomics tool [J]. Trends Plant Sci, 2004, 9(9):418-425.
    • (2004) Trends Plant Sci , vol.9 , Issue.9 , pp. 418-425
    • Bino, R.J.1    Hall, R.D.2    Fiehn, O.3
  • 91
    • 0037370412 scopus 로고    scopus 로고
    • Metabolic networks of cucurbita maxima phloem [J]
    • Fiehn O. Metabolic networks of cucurbita maxima phloem [J]. Phytochemistry, 2003, 62(6):875-886.
    • (2003) Phytochemistry , vol.62 , Issue.6 , pp. 875-886
    • Fiehn, O.1
  • 92
    • 34247586024 scopus 로고    scopus 로고
    • Analysis of Artemisia annua L. volatile oil by comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry [J]
    • Ma C, Wang H, Lu X, et al. Analysis of Artemisia annua L. volatile oil by comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry [J]. J Chromatogr A, 2007, 1150(1-2):50-53.
    • (2007) J Chromatogr A , vol.1150 , Issue.1-2 , pp. 50-53
    • Ma, C.1    Wang, H.2    Lu, X.3
  • 93
    • 85120112154 scopus 로고    scopus 로고
    • Ma C, Wang H, Lu X, et al. Metabolic fingerprinting investigation of Artemisia annua L. in different stages of development by gas chromatography and gas chromatography-mass spectrometry [J/OL]. J Chromatogr A, 2007, [2007-09-17]. http://www.ncbi.nlm.nih.gov/sites/ entrez?Db=puhmed&Cmd=ShowDetailView&TermToSearch= 17915234&ordinalpos=1&itool= EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum.
    • Ma C, Wang H, Lu X, et al. Metabolic fingerprinting investigation of Artemisia annua L. in different stages of development by gas chromatography and gas chromatography-mass spectrometry [J/OL]. J Chromatogr A, 2007, [2007-09-17]. http://www.ncbi.nlm.nih.gov/sites/ entrez?Db=puhmed&Cmd=ShowDetailView&TermToSearch= 17915234&ordinalpos=1&itool= EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum.
  • 94
    • 0026578070 scopus 로고
    • Evaluation of chromatographic methods for the detection of bacterial-contamination in biotechnical processes [J]
    • Elmroth I, Sundin P, Valeur A, et al. Evaluation of chromatographic methods for the detection of bacterial-contamination in biotechnical processes [J]. J Microbiol Methods, 1992, 15(3):215-228.
    • (1992) J Microbiol Methods , vol.15 , Issue.3 , pp. 215-228
    • Elmroth, I.1    Sundin, P.2    Valeur, A.3
  • 95
    • 11144257813 scopus 로고    scopus 로고
    • Discrimination of pathogenic clinical isolates and laboratorv strains of Bacillus cereus by NMR-based metabolomic profiling [J]
    • Bandy JG, Willey Th, Castell RS, et al. Discrimination of pathogenic clinical isolates and laboratorv strains of Bacillus cereus by NMR-based metabolomic profiling [J]. FEMS Microbiol Lett, 2005, 242(1):127-136.
    • (2005) FEMS Microbiol Lett , vol.242 , Issue.1 , pp. 127-136
    • Bandy, J.G.1    Willey, T.2    Castell, R.S.3
  • 96
    • 0035160371 scopus 로고    scopus 로고
    • A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations [J]
    • Raamsdonk LM, Teusink B, Broadhurst D, et al. A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations [J]. Nat Biotechnol, 2001, 19(1):45-50.
    • (2001) Nat Biotechnol , vol.19 , Issue.1 , pp. 45-50
    • Raamsdonk, L.M.1    Teusink, B.2    Broadhurst, D.3
  • 97
    • 0036298294 scopus 로고    scopus 로고
    • Metabolomics: Quantification of intracellular metabolite dynamics [J]
    • Buchholz A, Hurlebaus J, Wandrey C, et al. Metabolomics: quantification of intracellular metabolite dynamics [J]. Biomol Eng, 2002, 19(1):5-15.
    • (2002) Biomol Eng , vol.19 , Issue.1 , pp. 5-15
    • Buchholz, A.1    Hurlebaus, J.2    Wandrey, C.3
  • 98
    • 0035922877 scopus 로고    scopus 로고
    • Metabolic oscillations in an E-coli fermentation [J]
    • Andersen DC, Swartz J, Ryll T, et al. Metabolic oscillations in an E-coli fermentation [J]. Biotechnol Bioeng, 2001, 75(2):212-218.
    • (2001) Biotechnol Bioeng , vol.75 , Issue.2 , pp. 212-218
    • Andersen, D.C.1    Swartz, J.2    Ryll, T.3
  • 99
    • 0034847930 scopus 로고    scopus 로고
    • Dauner M, Bailey JE, Sauer U. Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis [J]. Biotecbnol Bioeng, 2001, 76(2):144-156.
    • Dauner M, Bailey JE, Sauer U. Metabolic flux analysis with a comprehensive isotopomer model in Bacillus subtilis [J]. Biotecbnol Bioeng, 2001, 76(2):144-156.
  • 100
    • 3242667214 scopus 로고    scopus 로고
    • Potential of fermentation profiling via rapid measurement of amino acid metabolism by liquid chromatography-tandem mass spectrometry [J]
    • Dalluge JJ, Smith S, Sanchez-Riera F, et al. Potential of fermentation profiling via rapid measurement of amino acid metabolism by liquid chromatography-tandem mass spectrometry [J]. J Chromatogr A, 2004, 1043(1):3-7.
    • (2004) J Chromatogr A , vol.1043 , Issue.1 , pp. 3-7
    • Dalluge, J.J.1    Smith, S.2    Sanchez-Riera, F.3
  • 101
    • 0034743610 scopus 로고    scopus 로고
    • F-19 NMR metabolomics for the elucidation of microbial degradation pathways of fluorophenols [J]
    • Boersma MG, Solyanikova IP, van Berkel WJH, et al. F-19 NMR metabolomics for the elucidation of microbial degradation pathways of fluorophenols [J]. J Ind Microbiol Biotechnol, 2001, 26(1-2):22-34.
    • (2001) J Ind Microbiol Biotechnol , vol.26 , Issue.1-2 , pp. 22-34
    • Boersma, M.G.1    Solyanikova, I.P.2    van Berkel, W.J.H.3
  • 102
    • 0038521716 scopus 로고    scopus 로고
    • Enhancement of plant-microbe interactions using a rhizosphere metabolomics-driven approach and its application in the removal of polychlorinated biphenyls [J]
    • Narasimhan K, Basheer C, Bajic VB, et al. Enhancement of plant-microbe interactions using a rhizosphere metabolomics-driven approach and its application in the removal of polychlorinated biphenyls [J]. Plant Physiol, 2003, 132 (1):146-153.
    • (2003) Plant Physiol , vol.132 , Issue.1 , pp. 146-153
    • Narasimhan, K.1    Basheer, C.2    Bajic, V.B.3
  • 103
    • 34047270405 scopus 로고    scopus 로고
    • Investigation on response of the metabolites in tricarboxylic acid cycle of Escherichi coli and Pseudomonas aeruginosa to antibiotic perturbation by capillary electrophoresis [J]
    • Gao P, Shi CY, Tian J, et al. Investigation on response of the metabolites in tricarboxylic acid cycle of Escherichi coli and Pseudomonas aeruginosa to antibiotic perturbation by capillary electrophoresis [J]. J Pharm Biomed Anal, 2007, 44(1):180-187.
    • (2007) J Pharm Biomed Anal , vol.44 , Issue.1 , pp. 180-187
    • Gao, P.1    Shi, C.Y.2    Tian, J.3


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