CD40-CD40 ligand interactions in human microglia induce CXCL8 (interleukin-8) secretion by a mechanism dependent on activation of ERK1/2 and nuclear translocation of nuclear factor-κB (NFκB) and activator protein-1 (AP-1)

Journal of Neuroscience Research

Volumn 86, Issue 3, 2008, Pages 630-639

  D'Aversa, Teresa G ^a,b   Eugenin, Eliseo A ^a   Berman, Joan W ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b IONA COLLEGE   (United States)

Author keywords

Chemokines; HIV dementia; Microglia; Neuro AIDS

Indexed keywords

CD40 LIGAND; CHLORDANE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TRANSCRIPTION FACTOR AP 1;

ADULT; ARTICLE; BRAIN TISSUE; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; ENCEPHALITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; INFANT; MALE; MICROGLIA; NEUROPATHOLOGY; PRIORITY JOURNAL; WESTERN BLOTTING;

ADOLESCENT; ADULT; AIDS DEMENTIA COMPLEX; ANTIGENS, CD; ANTIGENS, CD40; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; BIOLOGICAL TRANSPORT; BRAIN; CD40 LIGAND; CELL NUCLEUS; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CHILD; CHILD, PRESCHOOL; ENCEPHALITIS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FETUS; HUMANS; INFANT; INTERFERON TYPE II; INTERLEUKIN-8; MALE; MAP KINASE SIGNALING SYSTEM; MICROGLIA; MIDDLE AGED; NF-KAPPA B; RNA, MESSENGER; TISSUE DISTRIBUTION; TRANSCRIPTION FACTOR AP-1;

EID: 38849152403     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21525     Document Type: Article

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