Evaluation of epigallocatechin gallate and related plant polyphenols as inhibitors of the FabG and FabI reductases of bacterial type II fatty-acid synthase

Journal of Biological Chemistry

Volumn 279, Issue 30, 2004, Pages 30994-31001

  Zhang, Yong Mei ^a   Rock, Charles O ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOSYNTHESIS; ENZYME INHIBITION; ENZYMES; METABOLITES; PLANTS (BOTANY);

EPIGALLOCATECHIN GALLATE (EGCG); FATTY ACID ELONGATION CYCLES; GREEN TEA EXTRACTS; PLANT POLYPHENOLS;

FATTY ACIDS;

ACETIC ACID; BACTERIAL ENZYME; BUTEIN; CATECHIN GALLATE; COUMESTROL; EPICATECHIN; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; FABG REDUCTASE; FABI REDUCTASE; FATTY ACID SYNTHASE; FISETIN; FUSTIN; GALLIC ACID; GALLIC ACID PROPYL ESTER; GALLOCATECHIN; GALLOCATECHIN GALLATE; ISOLIQUIRITIGENIN; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE; PICEATANNOL; PLUMBAGIN; POLYPHENOL DERIVATIVE; QUERCETIN; RESVERATROL; RHEIN; TAXIFOLIN; THIOLACTOMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; EVALUATION; FATTY ACID SYNTHESIS; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; TEA;

ACETYLTRANSFERASES; ALCOHOL OXIDOREDUCTASES; ANTI-BACTERIAL AGENTS; CATECHIN; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); ENZYME INHIBITORS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FLAVONOIDS; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; OXIDOREDUCTASES; PHENOLS; TEA;

BACTERIA (MICROORGANISMS);

EID: 3843101649     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403697200     Document Type: Article

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