Suppression of fatty acid synthase in MCF-7 breast cancer cells by tea and tea polyphenols: A possible mechanism for their hypolipidemic effects

Pharmacogenomics Journal

Volumn 3, Issue 5, 2003, Pages 267-276

  Yeh, C W ^a   Chen, W J ^a   Chiang, C T ^a   Lin Shiau, S Y ^a   Lin, J K ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

EGF; FAS; Lipogenesis; MCF 7 breast cancer cell; P13K Akt Sp 1 signalling; Proliferation; Tea polyphenols

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTILIPEMIC AGENT; BLACK TEA EXTRACT; CATECHIN; EPICATECHIN; EPICATECHIN GALLATE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; FATTY ACID SYNTHASE; GALLOCATECHIN; GREEN TEA EXTRACT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; OOLONG TEA EXTRACT; PLANT EXTRACT; POLYPHENOL DERIVATIVE; PROTEIN KINASE B; THEAFLAVIN; THEAFLAVIN 3,3' DIGALLATE; THEAFLAVINE 3 GALLATE; THEAFLAVINE 3' GALLATE; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

AROMA; ARTICLE; BEVERAGE; BREAST CARCINOMA; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; ENZYME REPRESSION; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; ISOTOPE LABELING; LIPOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TEA;

CAMELLIA SINENSIS; MINK CELL FOCUS-FORMING VIRUS;

EID: 0242490895     PISSN: 1470269X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.tpj.6500192     Document Type: Article

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