메뉴 건너뛰기




Volumn 167, Issue 3, 2004, Pages 1293-1304

Selective and mutational patterns associated with gene expression in humans: Influences on synonymous composition and intron presence

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; TRANSFER RNA;

EID: 3843068862     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: 10.1534/genetics.104.026351     Document Type: Article
Times cited : (172)

References (95)
  • 1
    • 0028797897 scopus 로고
    • Inferring weak selection from patterns of polymorphism and divergence at "silent" sites in Drosophila DNA
    • AKASHI, H., 1995 Inferring weak selection from patterns of polymorphism and divergence at "silent" sites in Drosophila DNA. Genetics 139: 1067-1076.
    • (1995) Genetics , vol.139 , pp. 1067-1076
    • Akashi, H.1
  • 2
    • 0029985179 scopus 로고    scopus 로고
    • Molecular evolution between Drosophila melanogaster and D. simulons: Reduced codon bias, faster rates of amino acid substitution, and larger proteins in D. melanogaster
    • AKASHI, H., 1996 Molecular evolution between Drosophila melanogaster and D. simulons: reduced codon bias, faster rates of amino acid substitution, and larger proteins in D. melanogaster. Genetics 144: 1297-1307.
    • (1996) Genetics , vol.144 , pp. 1297-1307
    • Akashi, H.1
  • 3
    • 0041817645 scopus 로고    scopus 로고
    • Translational selection and yeast proteome evolution
    • AKASHI, H., 2003 Translational selection and yeast proteome evolution. Genetics 164: 1291-1303.
    • (2003) Genetics , vol.164 , pp. 1291-1303
    • Akashi, H.1
  • 4
    • 0037133671 scopus 로고    scopus 로고
    • Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis
    • AKASHI, H., and T. GOJOBORI, 2002 Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis. Proc. Natl. Acad. Sci. USA 99: 3695-3700.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 3695-3700
    • Akashi, H.1    Gojobori, T.2
  • 5
    • 0030801002 scopus 로고    scopus 로고
    • Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
    • ALTSCHUL, S. F., T. L. MADDEN, A. A. SCHAFFER, J. ZHANG, Z. ZHANG et al., 1997 Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25: 3389-3402.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3389-3402
    • Altschul, S.F.1    Madden, T.L.2    Schaffer, A.A.3    Zhang, J.4    Zhang, Z.5
  • 6
    • 0034938613 scopus 로고    scopus 로고
    • The frequency distribution of nucleotide variation in Drosophila simulans
    • BEGUN, D. J., 2001 The frequency distribution of nucleotide variation in Drosophila simulans. Mol. Biol. Evol. 18: 1343-1352.
    • (2001) Mol. Biol. Evol. , vol.18 , pp. 1343-1352
    • Begun, D.J.1
  • 7
    • 0029587471 scopus 로고
    • The human genome: Organization and evolutionary history
    • BERNARDI, G., 1995 The human genome: organization and evolutionary history. Annu. Rev. Genet. 29: 445-476.
    • (1995) Annu. Rev. Genet. , vol.29 , pp. 445-476
    • Bernardi, G.1
  • 8
    • 0037108764 scopus 로고    scopus 로고
    • Linkage limits the power of natural selection in Drosophila
    • BETANCOURT, A. J., and D. C. PRESGRAVES, 2002 Linkage limits the power of natural selection in Drosophila. Proc. Natl. Acad. Sci. USA 99: 13616-13620.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13616-13620
    • Betancourt, A.J.1    Presgraves, D.C.2
  • 9
    • 0025941139 scopus 로고
    • The selection-mutation-drift theory of synonymous codon usage
    • BULMER, M., 1991 The selection-mutation-drift theory of synonymous codon usage. Genetics 129: 897-907.
    • (1991) Genetics , vol.129 , pp. 897-907
    • Bulmer, M.1
  • 10
    • 0037274714 scopus 로고    scopus 로고
    • In vivo introduction of unpreferred synonymous codons into the Drosophila Adh gene results in reduced levels of ADH protein
    • CARLINI, D. B., and W. STEPHAN, 2003 In vivo introduction of unpreferred synonymous codons into the Drosophila Adh gene results in reduced levels of ADH protein. Genetics 163: 239-243.
    • (2003) Genetics , vol.163 , pp. 239-243
    • Carlini, D.B.1    Stephan, W.2
  • 11
    • 0345035503 scopus 로고    scopus 로고
    • Intron size and natural selection
    • CARVALHO, A. B., and A. G. CLARK, 1999 Intron size and natural selection. Nature 401: 344.
    • (1999) Nature , vol.401 , pp. 344
    • Carvalho, A.B.1    Clark, A.G.2
  • 13
    • 0034666040 scopus 로고    scopus 로고
    • Relationship of codon bias to mRNA concentration and protein length in Saccharomyces cerevisiae
    • COGHLAN, A., and K. H. WOLFE, 2000 Relationship of codon bias to mRNA concentration and protein length in Saccharomyces cerevisiae. Yeast 16: 1131-1145.
    • (2000) Yeast , vol.16 , pp. 1131-1145
    • Coghlan, A.1    Wolfe, K.H.2
  • 14
    • 0031694427 scopus 로고    scopus 로고
    • An evaluation of measures of synonymous codon usage bias
    • COMERON, J. M., and M. AGUADE, 1998 An evaluation of measures of synonymous codon usage bias. J. Mol. Evol. 47: 268-274.
    • (1998) J. Mol. Evol. , vol.47 , pp. 268-274
    • Comeron, J.M.1    Aguade, M.2
  • 15
    • 0033767383 scopus 로고    scopus 로고
    • The correlation between intron length and recombination in Drosophila: Dynamic equilibrium between mutational and selective forces
    • COMERON, J. M., and M. KREITMAN, 2000 The correlation between intron length and recombination in Drosophila: dynamic equilibrium between mutational and selective forces. Genetics 156: 1175-1190.
    • (2000) Genetics , vol.156 , pp. 1175-1190
    • Comeron, J.M.1    Kreitman, M.2
  • 16
    • 0036263105 scopus 로고    scopus 로고
    • Population, evolutionary and genomic consequences of interference selection
    • COMERON, J. M., and M. KREITMAN, 2002 Population, evolutionary and genomic consequences of interference selection. Genetics 161: 389-410.
    • (2002) Genetics , vol.161 , pp. 389-410
    • Comeron, J.M.1    Kreitman, M.2
  • 17
    • 0032894285 scopus 로고    scopus 로고
    • Natural selection on synonymous sites is correlated with gene length and recombination in Drosophila
    • COMERON, J. M., M. KREITMAN and M. AGUADE, 1999 Natural selection on synonymous sites is correlated with gene length and recombination in Drosophila. Genetics 151: 239-249.
    • (1999) Genetics , vol.151 , pp. 239-249
    • Comeron, J.M.1    Kreitman, M.2    Aguade, M.3
  • 18
    • 0026039804 scopus 로고
    • Selection of splice sites in pre-mRNAs with short internal exons
    • DOMINSKI, Z., and R. KOLE, 1991 Selection of splice sites in pre-mRNAs with short internal exons. Mol. Cell. Biol. 11: 6075-6083.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 6075-6083
    • Dominski, Z.1    Kole, R.2
  • 19
    • 0037202366 scopus 로고    scopus 로고
    • Expression patterns and gene distribution in the human genome
    • D'ONOFRIO, G., 2002 Expression patterns and gene distribution in the human genome. Gene 300: 155-160.
    • (2002) Gene , vol.300 , pp. 155-160
    • D'onofrio, G.1
  • 20
    • 0037320652 scopus 로고    scopus 로고
    • Synonymous mutations in the human dopamine receptor D2 (DRJD2) affect mRNA stability and synthesis of the receptor
    • DUAN, J., M. S. WAINWRICHT, J. M. COMERON, N. SAITOU, A. R. SANDERS et al., 2003 Synonymous mutations in the human dopamine receptor D2 (DRJD2) affect mRNA stability and synthesis of the receptor. Hum. Mol. Genet. 12: 205-216.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 205-216
    • Duan, J.1    Wainwricht, M.S.2    Comeron, J.M.3    Saitou, N.4    Sanders, A.R.5
  • 21
    • 0034237669 scopus 로고    scopus 로고
    • tRNA gene number and codon usage in the C. elegans genome are co-adapted for optimal translation of highly expressed genes
    • DURET, L., 2000 tRNA gene number and codon usage in the C. elegans genome are co-adapted for optimal translation of highly expressed genes. Trends Genet. 16: 287-289.
    • (2000) Trends Genet. , vol.16 , pp. 287-289
    • Duret, L.1
  • 22
    • 0036889468 scopus 로고    scopus 로고
    • Evolution of synonymous codon usage in metazoans
    • DURET, L., 2002 Evolution of synonymous codon usage in metazoans. Curr. Opin. Genet. Dev. 12: 640-649.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 640-649
    • Duret, L.1
  • 23
    • 0035035673 scopus 로고    scopus 로고
    • The elevated GC content at exonic third sites is not evidence against neutralist models of isochore evolution
    • DURET, L., and L. D. HURST, 2001 The elevated GC content at exonic third sites is not evidence against neutralist models of isochore evolution. Mol. Biol. Evol. 18: 757-762.
    • (2001) Mol. Biol. Evol. , vol.18 , pp. 757-762
    • Duret, L.1    Hurst, L.D.2
  • 24
    • 0033551151 scopus 로고    scopus 로고
    • Expression pattern and, surprisingly, gene length shape codon usage in Caenorhabditis, Drosophila, and Arabidopsis
    • DURET, L., and D. MOUCHIROUD, 1999 Expression pattern and, surprisingly, gene length shape codon usage in Caenorhabditis, Drosophila, and Arabidopsis. Proc. Natl. Acad. Sci. USA 96: 4482-4487.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4482-4487
    • Duret, L.1    Mouchiroud, D.2
  • 25
    • 0033977618 scopus 로고    scopus 로고
    • Determinants of substitution rates in mammalian genes: Expression pattern affects selection intensity but not mutation rate
    • DURET, L., and D. MOUCHIROUD, 2000 Determinants of substitution rates in mammalian genes: expression pattern affects selection intensity but not mutation rate. Mol. Biol. Evol. 17: 68-74.
    • (2000) Mol. Biol. Evol. , vol.17 , pp. 68-74
    • Duret, L.1    Mouchiroud, D.2
  • 26
    • 0028963020 scopus 로고
    • Statistical analysis of vertebrate sequences reveals that long genes are scarce in GC-rich isochores
    • DURET, L., D. MOUCHIROUD and C. GAUTIER, 1995 Statistical analysis of vertebrate sequences reveals that long genes are scarce in GC-rich isochores. J. Mol. Evol. 40: 308-317.
    • (1995) J. Mol. Evol. , vol.40 , pp. 308-317
    • Duret, L.1    Mouchiroud, D.2    Gautier, C.3
  • 28
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • EDGAR, R., M. DOMRACHEV and A. E. LASH, 2002 Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res. 30: 207-210.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 29
    • 0033018384 scopus 로고    scopus 로고
    • Evidence of selection on silent site base composition in mammals: Potential implications for the evolution of isochores and junk DNA
    • EYRE-WALKER, A., 1999 Evidence of selection on silent site base composition in mammals: potential implications for the evolution of isochores and junk DNA. Genetics 152: 675-683.
    • (1999) Genetics , vol.152 , pp. 675-683
    • Eyre-Walker, A.1
  • 30
    • 0016110957 scopus 로고
    • The evolutionary advantage of recombination
    • FELSENSTEIN J., 1974 The evolutionary advantage of recombination. Genetics 78: 737-756.
    • (1974) Genetics , vol.78 , pp. 737-756
    • Felsenstein, J.1
  • 31
    • 0035924345 scopus 로고    scopus 로고
    • Stimulatory effect of splicing factors on transcriptional elongation
    • FONG, Y. W., and Q. ZHOU, 2001 Stimulatory effect of splicing factors on transcriptional elongation. Nature 414: 929-933.
    • (2001) Nature , vol.414 , pp. 929-933
    • Fong, Y.W.1    Zhou, Q.2
  • 32
    • 0037303814 scopus 로고    scopus 로고
    • Gene conversion drives GC content evolution in mammalian histones
    • GALTIER, N., 2003 Gene conversion drives GC content evolution in mammalian histones. Trends Genet. 19: 65-68.
    • (2003) Trends Genet. , vol.19 , pp. 65-68
    • Galtier, N.1
  • 33
    • 0037380022 scopus 로고    scopus 로고
    • Transcription-associated mutational asymmetry in mammalian evolution
    • GREEN, P., B. EWING, W. MILLER, P. J. THOMAS and E. D. GREEN, 2003 Transcription-associated mutational asymmetry in mammalian evolution. Nat. Genet. 33: 514-517.
    • (2003) Nat. Genet. , vol.33 , pp. 514-517
    • Green, P.1    Ewing, B.2    Miller, W.3    Thomas, P.J.4    Green, E.D.5
  • 34
    • 0028596398 scopus 로고
    • Transcription-coupled repair and human disease
    • HANAWALT, P. C., 1994 Transcription-coupled repair and human disease. Science 266: 1957-1958.
    • (1994) Science , vol.266 , pp. 1957-1958
    • Hanawalt, P.C.1
  • 35
    • 0030722935 scopus 로고    scopus 로고
    • Long human-mouse sequence alignments reveal novel regulatory elements: A reason to sequence the mouse genome
    • HARDISON, R. C., J. OELTJEN and W. MILLER, 1997 Long human-mouse sequence alignments reveal novel regulatory elements: a reason to sequence the mouse genome. Genome Res. 7: 959-966.
    • (1997) Genome Res. , vol.7 , pp. 959-966
    • Hardison, R.C.1    Oeltjen, J.2    Miller, W.3
  • 36
    • 0027978722 scopus 로고
    • Selection intensity for codon bias
    • HARTL, D. L., E. N. MORIYAMA and S. A. SAWYER, 1994 Selection intensity for codon bias. Genetics 138: 227-234.
    • (1994) Genetics , vol.138 , pp. 227-234
    • Hartl, D.L.1    Moriyama, E.N.2    Sawyer, S.A.3
  • 37
    • 0036188913 scopus 로고    scopus 로고
    • Interactions between natural selection, recombination and gene density in the genes of Drosophila
    • HEY, J., and R. M. KLIMAN, 2002 Interactions between natural selection, recombination and gene density in the genes of Drosophila. Genetics 160: 595-608.
    • (2002) Genetics , vol.160 , pp. 595-608
    • Hey, J.1    Kliman, R.M.2
  • 38
    • 0013979181 scopus 로고
    • The effect of linkage on limits to artificial selection
    • HILL, W. G., and A. ROBERTSON, 1966 The effect of linkage on limits to artificial selection. Genet. Res. 8: 269-294.
    • (1966) Genet. Res. , vol.8 , pp. 269-294
    • Hill, W.G.1    Robertson, A.2
  • 39
    • 0034736528 scopus 로고    scopus 로고
    • A test of translational selection at 'silent' sites in the human genome: Base composition comparisons in alternatively spliced genes
    • IIDA, K., and H. AKASHI, 2000 A test of translational selection at 'silent' sites in the human genome: base composition comparisons in alternatively spliced genes. Gene 261: 93-105.
    • (2000) Gene , vol.261 , pp. 93-105
    • Iida, K.1    Akashi, H.2
  • 40
    • 0021958933 scopus 로고
    • Codon usage and tRNA content in unicellular and multicellular organisms
    • IKEMURA, T., 1985 Codon usage and tRNA content in unicellular and multicellular organisms. Mol. Biol. Evol. 2: 13-34.
    • (1985) Mol. Biol. Evol. , vol.2 , pp. 13-34
    • Ikemura, T.1
  • 41
    • 0034653294 scopus 로고    scopus 로고
    • Analysis of the yeast transcriptome with structural and functional categories: Characterizing highly expressed proteins
    • JANSEN, R., and M. GERSTEIN, 2000 Analysis of the yeast transcriptome with structural and functional categories: characterizing highly expressed proteins. Nucleic Acids Res. 28: 1481-1488.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 1481-1488
    • Jansen, R.1    Gerstein, M.2
  • 42
    • 0032884653 scopus 로고    scopus 로고
    • Comparative analysis of noncoding regions of 77 orthologous mouse and human gene pairs
    • JAREBORG, N., E. BIRNEY and R. DURBIN, 1999 Comparative analysis of noncoding regions of 77 orthologous mouse and human gene pairs. Genome Res. 9: 815-824.
    • (1999) Genome Res. , vol.9 , pp. 815-824
    • Jareborg, N.1    Birney, E.2    Durbin, R.3
  • 43
    • 0033634824 scopus 로고    scopus 로고
    • Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm
    • KATAOKA, N., J. YONG, V. N. KIM, F. VELAZQUEZ, R. A. PERKINSON el al., 2000 Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm. Mol. Cell 6: 673-682.
    • (2000) Mol. Cell , vol.6 , pp. 673-682
    • Kataoka, N.1    Yong, J.2    Kim, V.N.3    Velazquez, F.4    Perkinson, R.A.5
  • 44
    • 0027383354 scopus 로고
    • Reduced natural selection associated with low recombination in Drosophila melanogaster
    • KIIMAN, R. M., and J. HEY, 1993 Reduced natural selection associated with low recombination in Drosophila melanogaster. Mol. Biol. Evol. 10: 1239-1258.
    • (1993) Mol. Biol. Evol. , vol.10 , pp. 1239-1258
    • Kiiman, R.M.1    Hey, J.2
  • 45
    • 0022423415 scopus 로고
    • Size and position of intervening sequences are critical for the splicing efficiency of pre-mRNA in the yeast Saccharomyces cerevisiae
    • KLINZ, F.J., and D. GALLWITZ, 1985 Size and position of intervening sequences are critical for the splicing efficiency of pre-mRNA in the yeast Saccharomyces cerevisiae. Nucleic Acids Res. 13: 3791-3804.
    • (1985) Nucleic Acids Res. , vol.13 , pp. 3791-3804
    • Klinz, F.J.1    Gallwitz, D.2
  • 46
    • 0027104840 scopus 로고
    • Translational accuracy and the fitness of bacteria
    • KURLAND, C., 1992 Translational accuracy and the fitness of bacteria. Annu. Rev. Genet. 26: 29-50.
    • (1992) Annu. Rev. Genet. , vol.26 , pp. 29-50
    • Kurland, C.1
  • 47
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • LANDER, E. S., L. M. LINTON, B. BIRREN, C. NUSBAUM, M. C. ZODY el al., 2001 Initial sequencing and analysis of the human genome. Nature 409: 860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3    Nusbaum, C.4    Zody, M.C.5
  • 48
    • 0034193569 scopus 로고    scopus 로고
    • Pre-mRNA splicing alters mRNP composition: Evidence for stable association of proteins at exon-exon junctions
    • LE HIR, H., M.J. MOORE and L. E. MAQUAT, 2000 Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions. Genes Dev. 14: 1098-1108.
    • (2000) Genes Dev. , vol.14 , pp. 1098-1108
    • Le Hir, H.1    Moore, M.J.2    Maquat, L.E.3
  • 49
    • 0035801373 scopus 로고    scopus 로고
    • The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
    • LE HIR, H., D. GATFIELD, E. IZAURRALDE and M.J. MOORE, 2001 The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay. EMBO J. 20: 4987-4997.
    • (2001) EMBO J. , vol.20 , pp. 4987-4997
    • Le Hir, H.1    Gatfield, D.2    Izaurralde, E.3    Moore, M.J.4
  • 50
    • 0028799521 scopus 로고
    • Constraints on intron evolution in the gene encoding the myosin alkali light chain in Drosophila
    • LEICHT, B. G., S. V. MUSE, M. HANCZYC and A. G. CLARK, 1995 Constraints on intron evolution in the gene encoding the myosin alkali light chain in Drosophila. Genetics 139: 299-308.
    • (1995) Genetics , vol.139 , pp. 299-308
    • Leicht, B.G.1    Muse, S.V.2    Hanczyc, M.3    Clark, A.G.4
  • 51
    • 0036613754 scopus 로고    scopus 로고
    • Clustering of housekeeping genes provides a unified model of gene order in the human genome
    • LERCHER, M. J., A. O. URRUTIA and L. D. HURST, 2002 Clustering of housekeeping genes provides a unified model of gene order in the human genome. Nat. Genet. 31: 180-183.
    • (2002) Nat. Genet. , vol.31 , pp. 180-183
    • Lercher, M.J.1    Urrutia, A.O.2    Hurst, L.D.3
  • 53
    • 0023064998 scopus 로고
    • Models of nearly neutral mutations with particular implications for nonrandom usage of synonymous codons
    • LI, W. H., 1987 Models of nearly neutral mutations with particular implications for nonrandom usage of synonymous codons. J. Mol. Evol. 24: 337-345.
    • (1987) J. Mol. Evol. , vol.24 , pp. 337-345
    • Li, W.H.1
  • 54
    • 0026053092 scopus 로고
    • Low nucleotide diversity in man
    • LI, W. H., and L. A. SADLER, 1991 Low nucleotide diversity in man. Genetics 129: 513-523.
    • (1991) Genetics , vol.129 , pp. 513-523
    • Li, W.H.1    Sadler, L.A.2
  • 55
    • 0033927222 scopus 로고    scopus 로고
    • Nucleotide polymorphism at the RpII215 gene in Drosophila subobscura. Weak selection on synonymous mutations
    • LLOPART, A., and M. AGUADE, 2000 Nucleotide polymorphism at the RpII215 gene in Drosophila subobscura. Weak selection on synonymous mutations. Genetics 155: 1245-1252.
    • (2000) Genetics , vol.155 , pp. 1245-1252
    • Llopart, A.1    Aguade, M.2
  • 56
    • 0037062440 scopus 로고    scopus 로고
    • Intron presence-absence polymorphism in Drosophila driven by positive Darwinian selection
    • LLOPART, A., J. M. COMERON, F. G. BRUNET, D. LACHAISE and M. LONG, 2002 Intron presence-absence polymorphism in Drosophila driven by positive Darwinian selection. Proc. Natl. Acad. Sci. USA 99: 8121-8126.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 8121-8126
    • Llopart, A.1    Comeron, J.M.2    Brunet, F.G.3    Lachaise, D.4    Long, M.5
  • 57
    • 0037197986 scopus 로고    scopus 로고
    • Intron evolution as a population-genetic process
    • LYNCH, M., 2002 Intron evolution as a population-genetic process. Proc. Natl. Acad. Sci. USA 99: 6118-6123.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 6118-6123
    • Lynch, M.1
  • 58
    • 0042887665 scopus 로고    scopus 로고
    • Dependence of mutational asymmetry on gene-expression levels in the human genome
    • MAJEWSKI, J., 2003 Dependence of mutational asymmetry on gene-expression levels in the human genome. Am. J. Hum. Genet. 73: 688-692.
    • (2003) Am. J. Hum. Genet. , vol.73 , pp. 688-692
    • Majewski, J.1
  • 59
    • 0036911605 scopus 로고    scopus 로고
    • Distribution and characterization of regulatory elements in the human genome
    • MAJEWSKI, J., and J. OTT, 2002 Distribution and characterization of regulatory elements in the human genome. Genome Res. 12: 1827-1836.
    • (2002) Genome Res. , vol.12 , pp. 1827-1836
    • Majewski, J.1    Ott, J.2
  • 60
    • 0035877813 scopus 로고    scopus 로고
    • Identification and prevention of a GC content bias in SAGE libraries
    • MARGULIES, E. H., S. L. KARDIA and J. W. INNIS, 2001 Identification and prevention of a GC content bias in SAGE libraries. Nucleic Acids Res. 29: E60.
    • (2001) Nucleic Acids Res. , vol.29
    • Margulies, E.H.1    Kardia, S.L.2    Innis, J.W.3
  • 61
    • 0034099647 scopus 로고    scopus 로고
    • The effects of Hill-Robertson interference between weakly selected mutations on patterns of molecular evolution and variation
    • MCVEAN, G. A., and B. CHARLESWORTH, 2000 The effects of Hill-Robertson interference between weakly selected mutations on patterns of molecular evolution and variation. Genetics 155: 929-944.
    • (2000) Genetics , vol.155 , pp. 929-944
    • Mcvean, G.A.1    Charlesworth, B.2
  • 62
    • 0035157374 scopus 로고    scopus 로고
    • Inferring parameters of mutation, selection and demography from patterns of synonymous site evolution in Drosophila
    • MCVEAN, G. A., and J. VIEIRA, 2001 Inferring parameters of mutation, selection and demography from patterns of synonymous site evolution in Drosophila. Genetics 157: 245-257.
    • (2001) Genetics , vol.157 , pp. 245-257
    • Mcvean, G.A.1    Vieira, J.2
  • 63
    • 0027153966 scopus 로고
    • Codon usage bias and base composition of nuclear genes in Drosophila
    • MORIYAMA, E. N., and D. L. HARTL, 1993 Codon usage bias and base composition of nuclear genes in Drosophila. Genetics 134: 847-858.
    • (1993) Genetics , vol.134 , pp. 847-858
    • Moriyama, E.N.1    Hartl, D.L.2
  • 64
    • 0030731696 scopus 로고    scopus 로고
    • Codon usage bias and tRNA abundance in Drosophila
    • MORIYAMA, E. N., and J. R. POWELL, 1997 Codon usage bias and tRNA abundance in Drosophila. J. Mol. Evol. 45: 514-523.
    • (1997) J. Mol. Evol. , vol.45 , pp. 514-523
    • Moriyama, E.N.1    Powell, J.R.2
  • 65
    • 0032126484 scopus 로고    scopus 로고
    • Gene length and codon usage bias in Drosophila melanogaster, Saccharomyces cerevisiae and Escherichia coli
    • MORIYAMA, E. N., and J. R. POWELL, 1998 Gene length and codon usage bias in Drosophila melanogaster, Saccharomyces cerevisiae and Escherichia coli. Nucleic Acids Res. 26: 3188-3193.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 3188-3193
    • Moriyama, E.N.1    Powell, J.R.2
  • 67
    • 0034520771 scopus 로고    scopus 로고
    • Assessment of compositional heterogeneity within and between eukaryotic genomes
    • NEKRUTENKO, A., and W. H. LI, 2000 Assessment of compositional heterogeneity within and between eukaryotic genomes. Genome Res. 10: 1986-1995.
    • (2000) Genome Res. , vol.10 , pp. 1986-1995
    • Nekrutenko, A.1    Li, W.H.2
  • 68
    • 0030586280 scopus 로고    scopus 로고
    • The size differences among mammalian introns are due to the accumulation of small deletions
    • OGATA, H., W. FUJIBUCHI and M. KANEHISA, 1996 The size differences among mammalian introns are due to the accumulation of small deletions. FEBS Lett. 390: 99-103.
    • (1996) FEBS Lett. , vol.390 , pp. 99-103
    • Ogata, H.1    Fujibuchi, W.2    Kanehisa, M.3
  • 69
    • 0031593238 scopus 로고    scopus 로고
    • Patterns and rates of indel evolution in processed pseudogenes from humans and murids
    • OPHIR, R., and D. GRAUR, 1997 Patterns and rates of indel evolution in processed pseudogenes from humans and murids. Gene 205: 191-202.
    • (1997) Gene , vol.205 , pp. 191-202
    • Ophir, R.1    Graur, D.2
  • 70
    • 0347361692 scopus 로고    scopus 로고
    • Selective constraints on intron evolution in Drosophila
    • PARSCH, J., 2003 Selective constraints on intron evolution in Drosophila. Genetics 165: 1843-1851.
    • (2003) Genetics , vol.165 , pp. 1843-1851
    • Parsch, J.1
  • 71
    • 17444449538 scopus 로고    scopus 로고
    • Transfer RNA gene redundancy and translational selection in Saccharomyces cerevisiae
    • PERCUDANI, R., A. PAVESI and S. OTTONELLO, 1997 Transfer RNA gene redundancy and translational selection in Saccharomyces cerevisiae. J. Mol. Biol. 268: 322-330.
    • (1997) J. Mol. Biol. , vol.268 , pp. 322-330
    • Percudani, R.1    Pavesi, A.2    Ottonello, S.3
  • 72
    • 0030861159 scopus 로고    scopus 로고
    • Evolution of codon usage bias in Drosophila
    • POWELL, J. R., and E. N. MORIYAMA, 1997 Evolution of codon usage bias in Drosophila. Proc. Natl. Acad. Sci. USA 94: 7784-7790.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7784-7790
    • Powell, J.R.1    Moriyama, E.N.2
  • 73
    • 0000625869 scopus 로고
    • Analyzing tables of statistical tests
    • RICE, W. R., 1989 Analyzing tables of statistical tests. Evolution 43: 223-225.
    • (1989) Evolution , vol.43 , pp. 223-225
    • Rice, W.R.1
  • 74
    • 0036999964 scopus 로고    scopus 로고
    • Molecular population genetics of sequence length diversity in the Adh region of Drosophila pseudoobscura
    • SCHAEFFER, S. W., 2002 Molecular population genetics of sequence length diversity in the Adh region of Drosophila pseudoobscura. Genet. Res. 80: 163-175.
    • (2002) Genet. Res. , vol.80 , pp. 163-175
    • Schaeffer, S.W.1
  • 76
    • 0022856787 scopus 로고
    • An evolutionary perspective on synonymous codon usage in unicellular organisms
    • SHARP, P. M., and W. H. LI, 1986 An evolutionary perspective on synonymous codon usage in unicellular organisms. J. Mol. Evol. 24: 28-38.
    • (1986) J. Mol. Evol. , vol.24 , pp. 28-38
    • Sharp, P.M.1    Li, W.H.2
  • 77
    • 0023650543 scopus 로고
    • The codon Adaptation Index-a measure of directional synonymous codon usage bias, and its potential applications
    • SHARP, P. M., and W. H. LI, 1987 The codon Adaptation Index-a measure of directional synonymous codon usage bias, and its potential applications. Nucleic Acids Res. 15: 1281-1295.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 1281-1295
    • Sharp, P.M.1    Li, W.H.2
  • 78
    • 0033529188 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms can cause different structural folds of mRNA
    • SHEN, L. X., J. P. BASILION and V. P. STANTON, JR., 1999 Single-nucleotide polymorphisms can cause different structural folds of mRNA. Proc. Natl. Acad. Sci. USA 96: 7871-7876.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7871-7876
    • Shen, L.X.1    Basilion, J.P.2    Stanton Jr., V.P.3
  • 79
    • 0024116811 scopus 로고
    • "Silent" sites in Drosophila genes are not neutral: Evidence of selection among synonymous codons
    • SHIELDS, D., P. SHARP, D. HIGGINS and F. WRIGHT, 1988 "Silent" sites in Drosophila genes are not neutral: evidence of selection among synonymous codons. Mol. Biol. Evol. 5: 704-716.
    • (1988) Mol. Biol. Evol. , vol.5 , pp. 704-716
    • Shields, D.1    Sharp, P.2    Higgins, D.3    Wright, F.4
  • 80
    • 0027963390 scopus 로고
    • Molecular evolution of the metallothionein gene Mtn in the melanogaster species group: Results from Drosophila ananassae
    • STEPHAN, W., V. S. RODRIGUEZ, B. ZHOU and J. PARSCH, 1994 Molecular evolution of the metallothionein gene Mtn in the melanogaster species group: results from Drosophila ananassae. Genetics 138: 135-143.
    • (1994) Genetics , vol.138 , pp. 135-143
    • Stephan, W.1    Rodriguez, V.S.2    Zhou, B.3    Parsch, J.4
  • 83
    • 0029557771 scopus 로고
    • DNA excision repair and transcription: Implications for genome evolution
    • SULLIVAN, D. T., 1995 DNA excision repair and transcription: implications for genome evolution. Curr. Opin. Genet. Dev. 5: 786-791.
    • (1995) Curr. Opin. Genet. Dev. , vol.5 , pp. 786-791
    • Sullivan, D.T.1
  • 84
    • 0033956022 scopus 로고    scopus 로고
    • mRNA surveillance in mammalian cells: The relationship between introns and translation termination
    • SUN, X., and L. E. MAQUAT, 2000 mRNA surveillance in mammalian cells: the relationship between introns and translation termination. RNA 6: 1-8.
    • (2000) RNA , vol.6 , pp. 1-8
    • Sun, X.1    Maquat, L.E.2
  • 85
    • 0036363646 scopus 로고    scopus 로고
    • Mechanisms of transcription-coupled DNA repair
    • SVEJSTRUP, J. Q., 2002 Mechanisms of transcription-coupled DNA repair. Nat. Rev. Mol. Cell. Biol. 3: 21-29.
    • (2002) Nat. Rev. Mol. Cell. Biol. , vol.3 , pp. 21-29
    • Svejstrup, J.Q.1
  • 86
    • 0033939003 scopus 로고    scopus 로고
    • Molecular evolution in a multisite nearly neutral mutation model
    • TACHIDA, H., 2000 Molecular evolution in a multisite nearly neutral mutation model. J. Mol. Evol. 50: 69-81.
    • (2000) J. Mol. Evol. , vol.50 , pp. 69-81
    • Tachida, H.1
  • 87
    • 0022550189 scopus 로고
    • Exon/intron organization of the chicken type II procollagen gene: Intron size distribution suggests a minimal intron size
    • UPHOLT, W. B., and L. J. SANDELL, 1986 Exon/intron organization of the chicken type II procollagen gene: intron size distribution suggests a minimal intron size. Proc. Natl. Acad. Sci. USA 83: 2325-2329.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2325-2329
    • Upholt, W.B.1    Sandell, L.J.2
  • 88
    • 0035671698 scopus 로고    scopus 로고
    • Codon usage bias covaries with expression breadth and the rate of synonymous evolution in humans, but this is not evidence for selection
    • URRUTIA, A. O., and L. D. HURST, 2001 Codon usage bias covaries with expression breadth and the rate of synonymous evolution in humans, but this is not evidence for selection. Genetics 159: 1191-1199.
    • (2001) Genetics , vol.159 , pp. 1191-1199
    • Urrutia, A.O.1    Hurst, L.D.2
  • 89
    • 0142092546 scopus 로고    scopus 로고
    • The signature of selection mediated by expression on human genes
    • URRUTIA, A. O., and L. D. HURST, 2003 The signature of selection mediated by expression on human genes. Genome Res. 13: 2260-2264.
    • (2003) Genome Res. , vol.13 , pp. 2260-2264
    • Urrutia, A.O.1    Hurst, L.D.2
  • 90
    • 0037277564 scopus 로고    scopus 로고
    • Estimating ancestral population sizes and divergence times
    • WALL, J. D., 2003 Estimating ancestral population sizes and divergence times. Genetics 163: 395-404.
    • (2003) Genetics , vol.163 , pp. 395-404
    • Wall, J.D.1
  • 92
    • 0025318864 scopus 로고
    • The 'effective number of codons' used in a gene
    • WRIGHT, F., 1990 The 'effective number of codons' used in a gene. Gene 87: 23-29.
    • (1990) Gene , vol.87 , pp. 23-29
    • Wright, F.1
  • 94
    • 0034699472 scopus 로고    scopus 로고
    • The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans
    • ZHOU, Z., M. J. LUO, K. STRAESSER, J. KATAHIRA, E. HURT et al., 2000 The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans. Nature 407: 401-405.
    • (2000) Nature , vol.407 , pp. 401-405
    • Zhou, Z.1    Luo, M.J.2    Straesser, K.3    Katahira, J.4    Hurt, E.5
  • 95
    • 0030603239 scopus 로고    scopus 로고
    • The gene distribution of the human genome
    • ZOUBAK, S., O. CLAY and G. BERNARDI, 1996 The gene distribution of the human genome. Gene 174: 95-102.
    • (1996) Gene , vol.174 , pp. 95-102
    • Zoubak, S.1    Clay, O.2    Bernardi, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.