Role of receptor internalization in opioid tolerance and dependence

Pharmacology and Therapeutics

Volumn 117, Issue 2, 2008, Pages 199-206

  Koch, Thomas ^a   Höllt, Volker ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Dependence; Desensitization; Endocytosis; Internalization; Opioid receptor; Tolerance

Indexed keywords

FENTANYL; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; OPIATE;

CELL SURFACE; DESENSITIZATION; DOWN REGULATION; DRUG DEPENDENCE; DRUG TOLERANCE; ENDOCYTOSIS; HUMAN; IN VIVO STUDY; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; UPREGULATION;

ANALGESICS, OPIOID; ANIMALS; CYCLIC AMP; DOWN-REGULATION; DRUG TOLERANCE; ENDOCYTOSIS; HUMANS; OPIOID-RELATED DISORDERS; PHOSPHORYLATION; RECEPTORS, OPIOID; RECEPTORS, OPIOID, MU; SECOND MESSENGER SYSTEMS; TIME FACTORS; UP-REGULATION;

EID: 38349103412     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2007.10.003     Document Type: Review

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