Phosphorylation of Ser363, Thr370, and Ser 375 Residues within the Carboxyl Tail Differentially Regulates μ-Opioid Receptor Internalization

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 12774-12780

  El Kouhen, Rachid ^a   Burd, Amy L ^b   Erickson Herbrandson, Laurie J ^c   Chang, Chia Yu ^c   Law, Ping Yee ^c   Loh, Horace H ^c  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEXATION; CYTOLOGY; MUTAGENESIS; REACTION KINETICS;

PHOSPHORYLATION;

BIOCHEMISTRY;

ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; SERINE; THREONINE; ALANINE; DIPRENORPHINE; PHOSPHATE; PHOSPHOSERINE; PHOSPHOTHREONINE; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DESENSITIZATION; EMBRYO; GENE CONSTRUCT; HORMONE RECEPTOR TRANSLOCATION; HUMAN; HUMAN CELL; INTERNALIZATION; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY; AMINO ACID SUBSTITUTION; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECT; ENDOCYTOSIS; GENETIC TRANSFECTION; KINETICS; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; RAT; SITE DIRECTED MUTAGENESIS;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; DIPRENORPHINE; ENDOCYTOSIS; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; HUMANS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHATES; PHOSPHORYLATION; PHOSPHOSERINE; PHOSPHOTHREONINE; RATS; RECEPTORS, OPIOID, MU; RECOMBINANT PROTEINS; SERINE; THREONINE; TRANSFECTION;

EID: 0035918284     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009571200     Document Type: Article

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