Tolerance to morphine at the μ-opioid receptor differentially induced by cAMP-dependent protein kinase activation and morphine

European Journal of Pharmacology

Volumn 389, Issue 2-3, 2000, Pages 165-171

  Wang, Zaijie ^a,b   Sadée, Wolfgang ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Opioid receptor; cAMP dependent protein kinase; Desensitization; Morphine; N (2 aminoethyl) 5 isoquinolinesulfonamide (H8); Tolerance

Indexed keywords

8 BROMO CYCLIC AMP; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; MORPHINE; MU OPIATE RECEPTOR; N (2 METHYLAMINOETHYL) 5 ISOQUINOLINESULFONAMIDE;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVATION; DRUG TOLERANCE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DRUG TOLERANCE; ENZYME ACTIVATION; FORSKOLIN; HUMANS; MORPHINE; NARCOTICS; PHOSPHORYLATION; RECEPTORS, OPIOID, MU; TUMOR CELLS, CULTURED;

EID: 0034681348     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00881-X     Document Type: Article

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